Result of FASTA (omim) for
pFN21AE4464
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4464, 486 aa
1>>>pF1KE4464 486 - 486 aa - 486 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9465+/-0.000396; mu= 15.0398+/- 0.025
mean_var=79.7091+/-16.616, 0's: 0 Z-trim(112.2): 25 B-trim: 1010 in 1/52
Lambda= 0.143655
statistics sampled from 20991 (21008) to 20991 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.609), E-opt: 0.2 (0.246), width: 16
Scan time: 7.890
The best scores are: opt bits E(85289)
XP_016870616 (OMIM: 610558) PREDICTED: target of r ( 486) 3186 670.3 3.4e-192
NP_077022 (OMIM: 610558) target of rapamycin compl ( 486) 3186 670.3 3.4e-192
XP_016870615 (OMIM: 610558) PREDICTED: target of r ( 522) 2130 451.4 2.8e-126
NP_001006618 (OMIM: 610558) target of rapamycin co ( 522) 2130 451.4 2.8e-126
NP_001006620 (OMIM: 610558) target of rapamycin co ( 475) 2121 449.5 9.3e-126
NP_001006619 (OMIM: 610558) target of rapamycin co ( 323) 2115 448.2 1.6e-125
XP_011517308 (OMIM: 610558) PREDICTED: target of r ( 533) 2079 440.9 4.3e-123
XP_011517311 (OMIM: 610558) PREDICTED: target of r ( 370) 1113 240.6 5.8e-63
XP_011517310 (OMIM: 610558) PREDICTED: target of r ( 482) 1113 240.6 7.3e-63
XP_011517309 (OMIM: 610558) PREDICTED: target of r ( 522) 1113 240.6 7.8e-63
XP_011517307 (OMIM: 610558) PREDICTED: target of r ( 569) 1113 240.7 8.4e-63
NP_001006621 (OMIM: 610558) target of rapamycin co ( 330) 1073 232.3 1.7e-60
NP_001006622 (OMIM: 610558) target of rapamycin co ( 330) 1073 232.3 1.7e-60
XP_011517312 (OMIM: 610558) PREDICTED: target of r ( 330) 1073 232.3 1.7e-60
>>XP_016870616 (OMIM: 610558) PREDICTED: target of rapam (486 aa)
initn: 3186 init1: 3186 opt: 3186 Z-score: 3571.4 bits: 670.3 E(85289): 3.4e-192
Smith-Waterman score: 3186; 100.0% identity (100.0% similar) in 486 aa overlap (1-486:1-486)
10 20 30 40 50 60
pF1KE4 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 VDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 MKEILLKAVKRRKGSQKVSGSRADGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKEILLKAVKRRKGSQKVSGSRADGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TTDVQLGISGDKVEIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTDVQLGISGDKVEIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 YLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKE
430 440 450 460 470 480
pF1KE4 KKSGQQ
::::::
XP_016 KKSGQQ
>>NP_077022 (OMIM: 610558) target of rapamycin complex 2 (486 aa)
initn: 3186 init1: 3186 opt: 3186 Z-score: 3571.4 bits: 670.3 E(85289): 3.4e-192
Smith-Waterman score: 3186; 100.0% identity (100.0% similar) in 486 aa overlap (1-486:1-486)
10 20 30 40 50 60
pF1KE4 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 LPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 VDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 VDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 MKEILLKAVKRRKGSQKVSGSRADGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 MKEILLKAVKRRKGSQKVSGSRADGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TTDVQLGISGDKVEIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 TTDVQLGISGDKVEIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 YLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 YLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKE
430 440 450 460 470 480
pF1KE4 KKSGQQ
::::::
NP_077 KKSGQQ
>>XP_016870615 (OMIM: 610558) PREDICTED: target of rapam (522 aa)
initn: 2114 init1: 2114 opt: 2130 Z-score: 2388.2 bits: 451.4 E(85289): 2.8e-126
Smith-Waterman score: 3077; 93.1% identity (93.1% similar) in 518 aa overlap (1-482:1-518)
10 20 30 40 50 60
pF1KE4 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 VDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVT
250 260 270 280 290 300
310 320
pF1KE4 MKEILLKAVKRRKGSQKVSG------------------------------------SRAD
:::::::::::::::::::: ::::
XP_016 MKEILLKAVKRRKGSQKVSGPQYRLEKQSEPNVAVDLDSTLESQSAWEFCLVRENSSRAD
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE4 GVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRFTTDVQLGISGDKVEIDPVTNQKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRFTTDVQLGISGDKVEIDPVTNQKAS
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE4 TKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFESDAATVNEIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFESDAATVNEIVL
430 440 450 460 470 480
450 460 470 480
pF1KE4 KVNYILESRASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ
::::::::::::::::::::::::::::::::::::::
XP_016 KVNYILESRASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ
490 500 510 520
>>NP_001006618 (OMIM: 610558) target of rapamycin comple (522 aa)
initn: 2114 init1: 2114 opt: 2130 Z-score: 2388.2 bits: 451.4 E(85289): 2.8e-126
Smith-Waterman score: 3077; 93.1% identity (93.1% similar) in 518 aa overlap (1-482:1-518)
10 20 30 40 50 60
pF1KE4 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 VDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVT
250 260 270 280 290 300
310 320
pF1KE4 MKEILLKAVKRRKGSQKVSG------------------------------------SRAD
:::::::::::::::::::: ::::
NP_001 MKEILLKAVKRRKGSQKVSGPQYRLEKQSEPNVAVDLDSTLESQSAWEFCLVRENSSRAD
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE4 GVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRFTTDVQLGISGDKVEIDPVTNQKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRFTTDVQLGISGDKVEIDPVTNQKAS
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE4 TKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFESDAATVNEIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFESDAATVNEIVL
430 440 450 460 470 480
450 460 470 480
pF1KE4 KVNYILESRASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ
::::::::::::::::::::::::::::::::::::::
NP_001 KVNYILESRASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ
490 500 510 520
>>NP_001006620 (OMIM: 610558) target of rapamycin comple (475 aa)
initn: 2869 init1: 2114 opt: 2121 Z-score: 2378.7 bits: 449.5 E(85289): 9.3e-126
Smith-Waterman score: 2859; 91.8% identity (94.9% similar) in 486 aa overlap (1-486:1-475)
10 20 30 40 50 60
pF1KE4 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 VDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 MKEILLKAVKRRKGSQKVSGSRADGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRF
:::::::::::::::::::: . .:..:. ..:. :. :. . .: .:
NP_001 MKEILLKAVKRRKGSQKVSGPQYR--LEKQSEPNVAV--DLDSTLESQS-------AWEF
310 320 330 340
370 380 390 400 410 420
pF1KE4 TTDVQLGISGDKVEIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLT
. .:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLVRENSISGDKVEIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLT
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE4 YLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLSNHDYKHLYFESDAATVNEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKE
410 420 430 440 450 460
pF1KE4 KKSGQQ
::::::
NP_001 KKSGQQ
470
>>NP_001006619 (OMIM: 610558) target of rapamycin comple (323 aa)
initn: 2115 init1: 2115 opt: 2115 Z-score: 2374.5 bits: 448.2 E(85289): 1.6e-125
Smith-Waterman score: 2115; 99.7% identity (100.0% similar) in 321 aa overlap (1-321:1-321)
10 20 30 40 50 60
pF1KE4 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 VDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 MKEILLKAVKRRKGSQKVSGSRADGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRF
::::::::::::::::::::.
NP_001 MKEILLKAVKRRKGSQKVSGACD
310 320
>>XP_011517308 (OMIM: 610558) PREDICTED: target of rapam (533 aa)
initn: 2079 init1: 2079 opt: 2079 Z-score: 2330.9 bits: 440.9 E(85289): 4.3e-123
Smith-Waterman score: 2985; 90.9% identity (90.9% similar) in 518 aa overlap (16-486:16-533)
10 20 30 40 50 60
pF1KE4 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
70 80 90 100 110 120
130 140 150 160
pF1KE4 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGK--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKHCSSLCRIIMNKCF
130 140 150 160 170 180
170 180 190
pF1KE4 ---------------------------------GHVGTTATKKIDVYLPLHSSQDRLLPM
:::::::::::::::::::::::::::
XP_011 LQSLALNSSLQRKSLKTLQKSMKPPRNVANSEKGHVGTTATKKIDVYLPLHSSQDRLLPM
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE4 TVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGEVDTDFPPLDSNEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGEVDTDFPPLDSNEP
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE4 IHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVTMKEILLKAVKRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVTMKEILLKAVKRRK
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE4 GSQKVSGSRADGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRFTTDVQLGISGDKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSQKVSGSRADGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRFTTDVQLGISGDKV
370 380 390 400 410 420
380 390 400 410 420 430
pF1KE4 EIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFE
430 440 450 460 470 480
440 450 460 470 480
pF1KE4 SDAATVNEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDAATVNEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ
490 500 510 520 530
>>XP_011517311 (OMIM: 610558) PREDICTED: target of rapam (370 aa)
initn: 2107 init1: 1113 opt: 1113 Z-score: 1251.3 bits: 240.6 E(85289): 5.8e-63
Smith-Waterman score: 2011; 87.0% identity (87.2% similar) in 368 aa overlap (1-321:1-368)
10 20 30 40 50 60
pF1KE4 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
70 80 90 100 110 120
130 140 150 160
pF1KE4 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGK--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKHCSSLCRIIMNKCF
130 140 150 160 170 180
170 180 190
pF1KE4 ---------------------------------GHVGTTATKKIDVYLPLHSSQDRLLPM
:::::::::::::::::::::::::::
XP_011 LQSLALNSSLQRKSLKTLQKSMKPPRNVANSEKGHVGTTATKKIDVYLPLHSSQDRLLPM
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE4 TVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGEVDTDFPPLDSNEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGEVDTDFPPLDSNEP
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE4 IHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVTMKEILLKAVKRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVTMKEILLKAVKRRK
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE4 GSQKVSGSRADGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRFTTDVQLGISGDKV
:::::::.
XP_011 GSQKVSGACD
370
>>XP_011517310 (OMIM: 610558) PREDICTED: target of rapam (482 aa)
initn: 1397 init1: 1113 opt: 1113 Z-score: 1249.6 bits: 240.6 E(85289): 7.3e-63
Smith-Waterman score: 2230; 77.0% identity (79.7% similar) in 482 aa overlap (1-395:1-482)
10 20 30 40 50 60
pF1KE4 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
70 80 90 100 110 120
130 140 150 160
pF1KE4 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGK--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKHCSSLCRIIMNKCF
130 140 150 160 170 180
170 180 190
pF1KE4 ---------------------------------GHVGTTATKKIDVYLPLHSSQDRLLPM
:::::::::::::::::::::::::::
XP_011 LQSLALNSSLQRKSLKTLQKSMKPPRNVANSEKGHVGTTATKKIDVYLPLHSSQDRLLPM
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE4 TVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGEVDTDFPPLDSNEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGEVDTDFPPLDSNEP
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE4 IHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVTMKEILLKAVKRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVTMKEILLKAVKRRK
310 320 330 340 350 360
320 330
pF1KE4 GSQKVSG------------------------------------SRADGVFEEDSQIDIAT
::::::: :::::::::::::::::
XP_011 GSQKVSGPQYRLEKQSEPNVAVDLDSTLESQSAWEFCLVRENSSRADGVFEEDSQIDIAT
370 380 390 400 410 420
340 350 360 370 380 390
pF1KE4 VQDMLSSHHYKSFKVSMIHRLRFTTDVQLGISGDKVEIDPV----TNQKASTKFWIKQKP
::::::::::::::::::::::::::::: . . ... :. :.. . :. . . :
XP_011 VQDMLSSHHYKSFKVSMIHRLRFTTDVQLDVVYQPLRFLPLGPDLTSEFVPTQSYKQPLP
430 440 450 460 470 480
400 410 420 430 440 450
pF1KE4 ISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFESDAATVNEIVLKVNYILESR
:.
XP_011 IN
>>XP_011517309 (OMIM: 610558) PREDICTED: target of rapam (522 aa)
initn: 1868 init1: 1113 opt: 1113 Z-score: 1249.0 bits: 240.6 E(85289): 7.8e-63
Smith-Waterman score: 2728; 83.6% identity (86.4% similar) in 529 aa overlap (1-482:1-518)
10 20 30 40 50 60
pF1KE4 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
70 80 90 100 110 120
130 140 150 160
pF1KE4 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGK--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKHCSSLCRIIMNKCF
130 140 150 160 170 180
170 180 190
pF1KE4 ---------------------------------GHVGTTATKKIDVYLPLHSSQDRLLPM
:::::::::::::::::::::::::::
XP_011 LQSLALNSSLQRKSLKTLQKSMKPPRNVANSEKGHVGTTATKKIDVYLPLHSSQDRLLPM
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE4 TVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGEVDTDFPPLDSNEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGEVDTDFPPLDSNEP
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE4 IHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVTMKEILLKAVKRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVTMKEILLKAVKRRK
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE4 GSQKVSGSRADGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRFTTDVQLGISGDKV
::::::: . .:..:. ..:. :. :. . .: .: . .::::::
XP_011 GSQKVSGPQYR--LEKQSEPNVAV--DLDSTLESQS-------AWEFCLVRENSISGDKV
370 380 390 400
380 390 400 410 420 430
pF1KE4 EIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIDPVTNQKASTKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFE
410 420 430 440 450 460
440 450 460 470 480
pF1KE4 SDAATVNEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDAATVNEIVLKVNYILESRASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ
470 480 490 500 510 520
486 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:56:31 2016 done: Sun Nov 6 00:56:32 2016
Total Scan time: 7.890 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]