Result of FASTA (omim) for
pFN21AE4463
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4463, 480 aa
1>>>pF1KE4463 480 - 480 aa - 480 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2648+/-0.000451; mu= 18.3579+/- 0.028
mean_var=69.0650+/-13.916, 0's: 0 Z-trim(111.1): 64 B-trim: 16 in 1/53
Lambda= 0.154328
statistics sampled from 19527 (19591) to 19527 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.597), E-opt: 0.2 (0.23), width: 16
Scan time: 7.660
The best scores are: opt bits E(85289)
NP_001076440 (OMIM: 107930,608643) aromatic-L-amin ( 480) 3250 733.1 4.2e-211
NP_000781 (OMIM: 107930,608643) aromatic-L-amino-a ( 480) 3250 733.1 4.2e-211
XP_005271802 (OMIM: 107930,608643) PREDICTED: arom ( 442) 2516 569.6 6.2e-162
NP_001229815 (OMIM: 107930,608643) aromatic-L-amin ( 442) 2515 569.4 7.2e-162
XP_011513463 (OMIM: 107930,608643) PREDICTED: arom ( 461) 2506 567.4 3e-161
NP_001229817 (OMIM: 107930,608643) aromatic-L-amin ( 402) 2239 507.9 2.1e-143
NP_001229819 (OMIM: 107930,608643) aromatic-L-amin ( 338) 2138 485.4 1.1e-136
NP_002103 (OMIM: 137580,142704) histidine decarbox ( 662) 1825 415.9 1.8e-115
NP_001229818 (OMIM: 107930,608643) aromatic-L-amin ( 387) 1678 383.0 8.1e-106
NP_001229816 (OMIM: 107930,608643) aromatic-L-amin ( 432) 1675 382.4 1.4e-105
NP_001293075 (OMIM: 137580,142704) histidine decar ( 629) 1407 322.8 1.8e-87
XP_016877584 (OMIM: 137580,142704) PREDICTED: hist ( 664) 1215 280.1 1.4e-74
XP_016877588 (OMIM: 137580,142704) PREDICTED: hist ( 437) 1016 235.6 2.1e-61
XP_016877583 (OMIM: 137580,142704) PREDICTED: hist ( 697) 1016 235.8 3.1e-61
XP_016877587 (OMIM: 137580,142704) PREDICTED: hist ( 553) 797 186.9 1.2e-46
XP_016877586 (OMIM: 137580,142704) PREDICTED: hist ( 618) 797 187.0 1.3e-46
XP_016877585 (OMIM: 137580,142704) PREDICTED: hist ( 621) 697 164.7 6.7e-40
NP_001127838 (OMIM: 138275) glutamate decarboxylas ( 585) 456 111.0 9.1e-24
NP_000809 (OMIM: 138275) glutamate decarboxylase 2 ( 585) 456 111.0 9.1e-24
XP_011509224 (OMIM: 603513,605363) PREDICTED: glut ( 594) 453 110.4 1.5e-23
NP_000808 (OMIM: 603513,605363) glutamate decarbox ( 594) 453 110.4 1.5e-23
XP_016859245 (OMIM: 603513,605363) PREDICTED: glut ( 594) 453 110.4 1.5e-23
XP_016861786 (OMIM: 615601) PREDICTED: acidic amin ( 502) 438 107.0 1.3e-22
NP_997242 (OMIM: 615601) acidic amino acid decarbo ( 521) 438 107.0 1.3e-22
NP_001231634 (OMIM: 616569) cysteine sulfinic acid ( 493) 405 99.6 2.1e-20
XP_011536748 (OMIM: 616569) PREDICTED: cysteine su ( 520) 405 99.6 2.2e-20
NP_057073 (OMIM: 616569) cysteine sulfinic acid de ( 520) 405 99.6 2.2e-20
XP_016861787 (OMIM: 615601) PREDICTED: acidic amin ( 275) 370 91.7 2.9e-18
XP_011536753 (OMIM: 616569) PREDICTED: cysteine su ( 275) 368 91.2 3.9e-18
XP_016874907 (OMIM: 616569) PREDICTED: cysteine su ( 275) 368 91.2 3.9e-18
XP_016874906 (OMIM: 616569) PREDICTED: cysteine su ( 293) 360 89.5 1.4e-17
XP_011536751 (OMIM: 616569) PREDICTED: cysteine su ( 293) 360 89.5 1.4e-17
NP_001231635 (OMIM: 616569) cysteine sulfinic acid ( 260) 359 89.2 1.5e-17
XP_016874908 (OMIM: 616569) PREDICTED: cysteine su ( 368) 360 89.5 1.7e-17
XP_016874905 (OMIM: 616569) PREDICTED: cysteine su ( 422) 360 89.6 1.9e-17
XP_011536744 (OMIM: 616569) PREDICTED: cysteine su ( 551) 360 89.6 2.3e-17
XP_016859246 (OMIM: 603513,605363) PREDICTED: glut ( 395) 293 74.6 5.5e-13
>>NP_001076440 (OMIM: 107930,608643) aromatic-L-amino-ac (480 aa)
initn: 3250 init1: 3250 opt: 3250 Z-score: 3911.0 bits: 733.1 E(85289): 4.2e-211
Smith-Waterman score: 3250; 100.0% identity (100.0% similar) in 480 aa overlap (1-480:1-480)
10 20 30 40 50 60
pF1KE4 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
430 440 450 460 470 480
>>NP_000781 (OMIM: 107930,608643) aromatic-L-amino-acid (480 aa)
initn: 3250 init1: 3250 opt: 3250 Z-score: 3911.0 bits: 733.1 E(85289): 4.2e-211
Smith-Waterman score: 3250; 100.0% identity (100.0% similar) in 480 aa overlap (1-480:1-480)
10 20 30 40 50 60
pF1KE4 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
430 440 450 460 470 480
>>XP_005271802 (OMIM: 107930,608643) PREDICTED: aromatic (442 aa)
initn: 2944 init1: 2506 opt: 2516 Z-score: 3028.3 bits: 569.6 E(85289): 6.2e-162
Smith-Waterman score: 2872; 91.9% identity (92.1% similar) in 480 aa overlap (1-480:1-442)
10 20 30 40 50 60
pF1KE4 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
XP_005 MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
::::::: :::::::::::::::
XP_005 EKIIMPG--------------------------------------AASPACTELETVMMD
70 80
130 140 150 160 170 180
pF1KE4 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE4 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE4 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE4 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE4 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE4 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
390 400 410 420 430 440
>>NP_001229815 (OMIM: 107930,608643) aromatic-L-amino-ac (442 aa)
initn: 2948 init1: 2506 opt: 2515 Z-score: 3027.1 bits: 569.4 E(85289): 7.2e-162
Smith-Waterman score: 2876; 92.1% identity (92.1% similar) in 480 aa overlap (1-480:1-442)
10 20 30 40 50 60
pF1KE4 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
::::::: :::::::::::::::
NP_001 EKIIMPG--------------------------------------AASPACTELETVMMD
70 80
130 140 150 160 170 180
pF1KE4 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE4 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE4 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE4 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE4 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE4 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
390 400 410 420 430 440
>>XP_011513463 (OMIM: 107930,608643) PREDICTED: aromatic (461 aa)
initn: 2506 init1: 2506 opt: 2506 Z-score: 3016.0 bits: 567.4 E(85289): 3e-161
Smith-Waterman score: 2506; 100.0% identity (100.0% similar) in 375 aa overlap (106-480:87-461)
80 90 100 110 120 130
pF1KE4 FFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNE
::::::::::::::::::::::::::::::
XP_011 IRCVQSLGAGGSLEKGLAPACKPPVPPYLEAASPACTELETVMMDWLGKMLELPKAFLNE
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE4 KAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSV
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE4 ERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLL
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE4 EVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMW
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE4 VKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQ
300 310 320 330 340 350
380 390 400 410 420 430
pF1KE4 AYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVNEALLQRINSAKKIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVNEALLQRINSAKKIHL
360 370 380 390 400 410
440 450 460 470 480
pF1KE4 VPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
420 430 440 450 460
>>NP_001229817 (OMIM: 107930,608643) aromatic-L-amino-ac (402 aa)
initn: 2681 init1: 2239 opt: 2239 Z-score: 2695.6 bits: 507.9 E(85289): 2.1e-143
Smith-Waterman score: 2529; 83.8% identity (83.8% similar) in 480 aa overlap (1-480:1-402)
10 20 30 40 50 60
pF1KE4 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
:::::::
NP_001 EKIIMPG-----------------------------------------------------
130 140 150 160 170 180
pF1KE4 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
:::::::::::::::::::::::::::::::::::
NP_001 -------------------------GSASEATLVALLAARTKVIHRLQAASPELTQAAIM
70 80 90 100
190 200 210 220 230 240
pF1KE4 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE4 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE4 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE4 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
290 300 310 320 330 340
430 440 450 460 470 480
pF1KE4 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
350 360 370 380 390 400
>>NP_001229819 (OMIM: 107930,608643) aromatic-L-amino-ac (338 aa)
initn: 2160 init1: 2138 opt: 2138 Z-score: 2575.1 bits: 485.4 E(85289): 1.1e-136
Smith-Waterman score: 2138; 99.1% identity (99.7% similar) in 318 aa overlap (1-318:1-318)
10 20 30 40 50 60
pF1KE4 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
::::::::::::::: ..
NP_001 PHKWLLVNFDCSAMWSRQPVRMLRLKKTCLVSAVVRRS
310 320 330
>>NP_002103 (OMIM: 137580,142704) histidine decarboxylas (662 aa)
initn: 1811 init1: 814 opt: 1825 Z-score: 2194.2 bits: 415.9 E(85289): 1.8e-115
Smith-Waterman score: 1825; 52.1% identity (82.6% similar) in 476 aa overlap (1-475:2-475)
10 20 30 40 50
pF1KE4 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIIND
:. :.:.::.:::::. .:. .. :.: :::.::::: .: .::..::....:..:
NP_002 MMEPEEYRERGREMVDYICQYLSTVRERRVTPDVQPGYLRAQLPESAPEDPDSWDSIFGD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 VEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMM
.:.::::::.::.::.. ::.:. .:.:..:.::: ::.:.::.::.:::::::: .:
NP_002 IERIIMPGVVHWQSPHMHAYYPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNVM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 DWLGKMLELPKAFLNEK-AGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAA
:::.::: ::. ::... ...::::.:...::.::.:::::: . : ..... :. ..
NP_002 DWLAKMLGLPEHFLHHHPSSQGGGVLQSTVSESTLIALLAARKNKILEMKTSEPDADESC
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 IMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFF
. .::::.:::::::::.::::. ::.: .: : ::..:. :::.:.:.:: ::.: :
NP_002 LNARLVAYASDQAHSSVEKAGLISLVKMKFLPVDDNFSLRGEALQKAIEEDKQRGLVPVF
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 MVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFN
. :::::: :.:: : :.:::: .: .:::.::::::.::.::::: .:.:.:.::::.
NP_002 VCATLGTTGVCAFDCLSELGPICAREGLWLHIDAAYAGTAFLCPEFRGFLKGIEYADSFT
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 FNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFR
::: ::..:.:::...::: . : .: ..: ::.:. .::. ::. ::::::.::::
NP_002 FNPSKWMMVHFDCTGFWVKDKYKLQQTFSVNPIYLRHA--NSGVATDFMHWQIPLSRRFR
310 320 330 340 350
360 370 380 390 400 410
pF1KE4 SLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNK
:.:.:::.: .:::.:::..:. ..... ::::::.:: ::: .. :::: ::::: :
NP_002 SVKLWFVIRSFGVKNLQAHVRHGTEMAKYFESLVRNDPSFEIPAKRHLGLVVFRLKGPNC
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE4 VNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAE
..: .:..: .: .. :.: ..::...::.. :. . . : :. :.. :. .:
NP_002 LTENVLKEIAKAGRLFLIPATIQDKLIIRFTVTSQFTTRDDILRDWNLIRDAATLILSQH
420 430 440 450 460 470
480
pF1KE4 RE
NP_002 CTSQPSPRVGNLISQIRGARAWACGTSLQSVSGAGDDPVQARKIIKQPQRVGAGPMKREN
480 490 500 510 520 530
>>NP_001229818 (OMIM: 107930,608643) aromatic-L-amino-ac (387 aa)
initn: 2672 init1: 1675 opt: 1678 Z-score: 2020.8 bits: 383.0 E(85289): 8.1e-106
Smith-Waterman score: 2490; 80.6% identity (80.6% similar) in 480 aa overlap (1-480:1-387)
10 20 30 40 50 60
pF1KE4 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
:::::::::::::::::::::::::
NP_001 WLGKMLELPKAFLNEKAGEGGGVIQ-----------------------------------
130 140
190 200 210 220 230 240
pF1KE4 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
::
NP_001 ----------------------------------------------------------MV
250 260 270 280 290 300
pF1KE4 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
150 160 170 180 190 200
310 320 330 340 350 360
pF1KE4 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
210 220 230 240 250 260
370 380 390 400 410 420
pF1KE4 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
270 280 290 300 310 320
430 440 450 460 470 480
pF1KE4 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
330 340 350 360 370 380
>>NP_001229816 (OMIM: 107930,608643) aromatic-L-amino-ac (432 aa)
initn: 2933 init1: 1675 opt: 1675 Z-score: 2016.4 bits: 382.4 E(85289): 1.4e-105
Smith-Waterman score: 2841; 90.0% identity (90.0% similar) in 480 aa overlap (1-480:1-432)
10 20 30 40 50 60
pF1KE4 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV
:::::::::: ::
NP_001 EKLVAYSSDQ------------------------------------------------MV
190
250 260 270 280 290 300
pF1KE4 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE4 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE4 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE4 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
380 390 400 410 420 430
480 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:57:13 2016 done: Sun Nov 6 00:57:14 2016
Total Scan time: 7.660 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]