Result of FASTA (omim) for
pFN21AE4443
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4443, 459 aa
1>>>pF1KE4443 459 - 459 aa - 459 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7372+/-0.000309; mu= 12.4984+/- 0.019
mean_var=119.2478+/-23.696, 0's: 0 Z-trim(120.0): 168 B-trim: 224 in 1/57
Lambda= 0.117449
statistics sampled from 34565 (34733) to 34565 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.748), E-opt: 0.2 (0.407), width: 16
Scan time: 9.810
The best scores are: opt bits E(85289)
NP_536341 (OMIM: 603696) septin-4 isoform 3 [Homo ( 459) 3143 543.3 5.2e-154
XP_006722012 (OMIM: 603696) PREDICTED: septin-4 is ( 483) 3143 543.3 5.4e-154
NP_001185642 (OMIM: 603696) septin-4 isoform 4 [Ho ( 470) 3136 542.1 1.2e-153
NP_004565 (OMIM: 603696) septin-4 isoform 1 [Homo ( 478) 3136 542.1 1.2e-153
NP_001243711 (OMIM: 603696) septin-4 isoform 5 [Ho ( 493) 3136 542.1 1.3e-153
XP_006722013 (OMIM: 603696) PREDICTED: septin-4 is ( 384) 2429 422.2 1.2e-117
XP_006722014 (OMIM: 603696) PREDICTED: septin-4 is ( 379) 2428 422.0 1.3e-117
XP_006722015 (OMIM: 603696) PREDICTED: septin-4 is ( 360) 2415 419.8 5.9e-117
XP_011523213 (OMIM: 603696) PREDICTED: septin-4 is ( 331) 2227 388.0 2.1e-107
XP_006722018 (OMIM: 603696) PREDICTED: septin-4 is ( 331) 2227 388.0 2.1e-107
NP_001243751 (OMIM: 603696) septin-4 isoform 6 [Ho ( 331) 2227 388.0 2.1e-107
XP_006722017 (OMIM: 603696) PREDICTED: septin-4 is ( 331) 2227 388.0 2.1e-107
XP_011523214 (OMIM: 603696) PREDICTED: septin-4 is ( 331) 2227 388.0 2.1e-107
NP_002679 (OMIM: 602724) septin-5 isoform 1 [Homo ( 369) 1869 327.3 4.2e-89
NP_536340 (OMIM: 603696) septin-4 isoform 2 [Homo ( 274) 1723 302.5 9.3e-82
NP_443070 (OMIM: 612897) septin-1 [Homo sapiens] ( 414) 1618 284.8 2.9e-76
XP_016878480 (OMIM: 612897) PREDICTED: septin-1 is ( 494) 1535 270.8 5.8e-72
NP_001009939 (OMIM: 602724) septin-5 isoform 2 [Ho ( 346) 1474 260.4 5.6e-69
NP_001307963 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1385 245.3 2e-64
NP_001307962 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1385 245.3 2e-64
NP_001307959 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1385 245.3 2e-64
NP_004395 (OMIM: 601506) septin-2 isoform a [Homo ( 361) 1385 245.3 2e-64
NP_001307964 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1385 245.3 2e-64
NP_001008491 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1385 245.3 2e-64
XP_016859694 (OMIM: 601506) PREDICTED: septin-2 is ( 361) 1385 245.3 2e-64
NP_001008492 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1385 245.3 2e-64
NP_001307960 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1385 245.3 2e-64
NP_001307961 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1385 245.3 2e-64
NP_006146 (OMIM: 601506) septin-2 isoform a [Homo ( 361) 1385 245.3 2e-64
XP_016859695 (OMIM: 601506) PREDICTED: septin-2 is ( 361) 1385 245.3 2e-64
XP_016859691 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1385 245.3 2.1e-64
XP_016859689 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1385 245.3 2.1e-64
XP_016859683 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1385 245.3 2.1e-64
XP_016859693 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1385 245.3 2.1e-64
XP_016859687 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1385 245.3 2.1e-64
XP_016859690 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1385 245.3 2.1e-64
XP_016859685 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1385 245.3 2.1e-64
XP_016859684 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1385 245.3 2.1e-64
XP_016859682 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1385 245.3 2.1e-64
XP_016859692 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1385 245.3 2.1e-64
XP_016859688 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1385 245.3 2.1e-64
XP_016859686 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1385 245.3 2.1e-64
XP_016859679 (OMIM: 601506) PREDICTED: septin-2 is ( 436) 1386 245.5 2.1e-64
NP_001307958 (OMIM: 601506) septin-2 isoform d [Ho ( 391) 1385 245.3 2.2e-64
NP_001269901 (OMIM: 601506) septin-2 isoform b [Ho ( 396) 1385 245.3 2.2e-64
XP_016859681 (OMIM: 601506) PREDICTED: septin-2 is ( 428) 1385 245.4 2.3e-64
XP_016859680 (OMIM: 601506) PREDICTED: septin-2 is ( 428) 1385 245.4 2.3e-64
XP_016859678 (OMIM: 601506) PREDICTED: septin-2 is ( 441) 1385 245.4 2.4e-64
XP_011513963 (OMIM: 603151) PREDICTED: septin-7 is ( 440) 1289 229.1 1.9e-59
XP_016868344 (OMIM: 603151) PREDICTED: septin-7 is ( 445) 1289 229.1 1.9e-59
>>NP_536341 (OMIM: 603696) septin-4 isoform 3 [Homo sapi (459 aa)
initn: 3143 init1: 3143 opt: 3143 Z-score: 2885.9 bits: 543.3 E(85289): 5.2e-154
Smith-Waterman score: 3143; 100.0% identity (100.0% similar) in 459 aa overlap (1-459:1-459)
10 20 30 40 50 60
pF1KE4 MIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQAPDLYDDDLEFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 MIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQAPDLYDDDLEFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 PPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 PPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 KKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 VRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 ISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 FPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 FPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 FVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 FVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIP
370 380 390 400 410 420
430 440 450
pF1KE4 AVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
:::::::::::::::::::::::::::::::::::::::
NP_536 AVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
430 440 450
>>XP_006722012 (OMIM: 603696) PREDICTED: septin-4 isofor (483 aa)
initn: 3143 init1: 3143 opt: 3143 Z-score: 2885.6 bits: 543.3 E(85289): 5.4e-154
Smith-Waterman score: 3143; 100.0% identity (100.0% similar) in 459 aa overlap (1-459:25-483)
10 20 30
pF1KE4 MIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTW
::::::::::::::::::::::::::::::::::::
XP_006 MGPVPTSFGKRRGGPQTLPASPGGMIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTW
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE4 ASRPQVPEPRPQAPDLYDDDLEFRPPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASRPQVPEPRPQAPDLYDDDLEFRPPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPY
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE4 DSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE4 LGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQ
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE4 YFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE4 PPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEA
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE4 RGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSM
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE4 TRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMK
430 440 450 460 470 480
pF1KE4 ENY
:::
XP_006 ENY
>>NP_001185642 (OMIM: 603696) septin-4 isoform 4 [Homo s (470 aa)
initn: 3136 init1: 3136 opt: 3136 Z-score: 2879.4 bits: 542.1 E(85289): 1.2e-153
Smith-Waterman score: 3136; 100.0% identity (100.0% similar) in 458 aa overlap (2-459:13-470)
10 20 30 40
pF1KE4 MIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQA
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGFYSVMTDEEIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 PDLYDDDLEFRPPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDLYDDDLEFRPPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 TLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 TKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNI
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 QDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIRE
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 EIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWG
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE4 IVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKL
370 380 390 400 410 420
410 420 430 440 450
pF1KE4 TRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
430 440 450 460 470
>>NP_004565 (OMIM: 603696) septin-4 isoform 1 [Homo sapi (478 aa)
initn: 3136 init1: 3136 opt: 3136 Z-score: 2879.3 bits: 542.1 E(85289): 1.2e-153
Smith-Waterman score: 3136; 100.0% identity (100.0% similar) in 458 aa overlap (2-459:21-478)
10 20 30 40
pF1KE4 MIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQ
::::::::::::::::::::::::::::::::::::::::
NP_004 MDRSLGWQGNSVPEDRTEAGIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 VPEPRPQAPDLYDDDLEFRPPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VPEPRPQAPDLYDDDLEFRPPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSED
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEE
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 RIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDE
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 SGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVD
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 HKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRV
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE4 RGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVV
370 380 390 400 410 420
410 420 430 440 450
pF1KE4 KERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
430 440 450 460 470
>>NP_001243711 (OMIM: 603696) septin-4 isoform 5 [Homo s (493 aa)
initn: 3136 init1: 3136 opt: 3136 Z-score: 2879.1 bits: 542.1 E(85289): 1.3e-153
Smith-Waterman score: 3136; 100.0% identity (100.0% similar) in 458 aa overlap (2-459:36-493)
10 20 30
pF1KE4 MIKRFLEDTTDDGELSKFVKDFSGNASCHPP
::::::::::::::::::::::::::::::
NP_001 ALFSSRAAPQKPRKEGSQAAGLLVFSDSLEIKRFLEDTTDDGELSKFVKDFSGNASCHPP
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE4 EAKTWASRPQVPEPRPQAPDLYDDDLEFRPPSRPQSSDNQQYFCAPAPLSPSARPRSPWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAKTWASRPQVPEPRPQAPDLYDDDLEFRPPSRPQSSDNQQYFCAPAPLSPSARPRSPWG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE4 KLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLY
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE4 RDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYID
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE4 QQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAK
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE4 ADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSN
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE4 TVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQ
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE4 CIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKI
430 440 450 460 470 480
pF1KE4 QKQMKENY
::::::::
NP_001 QKQMKENY
490
>>XP_006722013 (OMIM: 603696) PREDICTED: septin-4 isofor (384 aa)
initn: 2415 init1: 2415 opt: 2429 Z-score: 2233.2 bits: 422.2 E(85289): 1.2e-117
Smith-Waterman score: 2429; 95.3% identity (96.6% similar) in 383 aa overlap (77-459:3-384)
50 60 70 80 90 100
pF1KE4 PQAPDLYDDDLEFRPPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYV
:.: : . : .: : .. ::::::
XP_006 MGPVPTSFGKRRGGPQ-TLPASPGGMDDKEYV
10 20 30
110 120 130 140 150 160
pF1KE4 GFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQT
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE4 VEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNR
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE4 KNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRK
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE4 IREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLY
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 PWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNR
280 290 300 310 320 330
410 420 430 440 450
pF1KE4 NKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
340 350 360 370 380
>>XP_006722014 (OMIM: 603696) PREDICTED: septin-4 isofor (379 aa)
initn: 2415 init1: 2415 opt: 2428 Z-score: 2232.4 bits: 422.0 E(85289): 1.3e-117
Smith-Waterman score: 2428; 97.6% identity (98.1% similar) in 373 aa overlap (90-459:7-379)
60 70 80 90 100 110
pF1KE4 RPPSRPQSSDNQQYFCAPAPLSPSARPRSPW-GKLDPYDSSE--DDKEYVGFATLPNQVH
: :. : : .: ::::::::::::::::
XP_006 MDRSLGWQGNSVPEDRTEAGDDKEYVGFATLPNQVH
10 20 30
120 130 140 150 160 170
pF1KE4 RKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDI
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE4 EEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHC
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE4 CLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGI
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE4 KIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENP
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE4 GHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTD
280 290 300 310 320 330
420 430 440 450
pF1KE4 FPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
:::::::::::::::::::::::::::::::::::::::::::
XP_006 FPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
340 350 360 370
>>XP_006722015 (OMIM: 603696) PREDICTED: septin-4 isofor (360 aa)
initn: 2415 init1: 2415 opt: 2415 Z-score: 2220.8 bits: 419.8 E(85289): 5.9e-117
Smith-Waterman score: 2415; 100.0% identity (100.0% similar) in 359 aa overlap (101-459:2-360)
80 90 100 110 120 130
pF1KE4 QQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMV
::::::::::::::::::::::::::::::
XP_006 MDDKEYVGFATLPNQVHRKSVKKGFDFTLMV
10 20 30
140 150 160 170 180 190
pF1KE4 AGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDT
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE4 PGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRP
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE4 LDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDE
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE4 DFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVR
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE4 THMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPGTDPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 THMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPGTDPET
280 290 300 310 320 330
440 450
pF1KE4 EKLIREKDEELRRMQEMLHKIQKQMKENY
:::::::::::::::::::::::::::::
XP_006 EKLIREKDEELRRMQEMLHKIQKQMKENY
340 350 360
>>XP_011523213 (OMIM: 603696) PREDICTED: septin-4 isofor (331 aa)
initn: 2227 init1: 2227 opt: 2227 Z-score: 2049.1 bits: 388.0 E(85289): 2.1e-107
Smith-Waterman score: 2227; 100.0% identity (100.0% similar) in 331 aa overlap (129-459:1-331)
100 110 120 130 140 150
pF1KE4 SEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLG
::::::::::::::::::::::::::::::
XP_011 MVAGESGLGKSTLVNSLFLTDLYRDRKLLG
10 20 30
160 170 180 190 200 210
pF1KE4 AEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYF
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE4 RDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPP
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE4 EVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARG
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE4 RRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTR
220 230 240 250 260 270
400 410 420 430 440 450
pF1KE4 LVVKERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVVKERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKEN
280 290 300 310 320 330
pF1KE4 Y
:
XP_011 Y
>>XP_006722018 (OMIM: 603696) PREDICTED: septin-4 isofor (331 aa)
initn: 2227 init1: 2227 opt: 2227 Z-score: 2049.1 bits: 388.0 E(85289): 2.1e-107
Smith-Waterman score: 2227; 100.0% identity (100.0% similar) in 331 aa overlap (129-459:1-331)
100 110 120 130 140 150
pF1KE4 SEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLG
::::::::::::::::::::::::::::::
XP_006 MVAGESGLGKSTLVNSLFLTDLYRDRKLLG
10 20 30
160 170 180 190 200 210
pF1KE4 AEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYF
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE4 RDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPP
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE4 EVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARG
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE4 RRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTR
220 230 240 250 260 270
400 410 420 430 440 450
pF1KE4 LVVKERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVVKERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKEN
280 290 300 310 320 330
pF1KE4 Y
:
XP_006 Y
459 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 22:37:50 2016 done: Sat Nov 5 22:37:51 2016
Total Scan time: 9.810 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]