Result of FASTA (omim) for
pFN21AE4418
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4418, 431 aa
1>>>pF1KE4418 431 - 431 aa - 431 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2899+/-0.000555; mu= 6.9803+/- 0.034
mean_var=166.5503+/-36.220, 0's: 0 Z-trim(109.5): 259 B-trim: 29 in 1/53
Lambda= 0.099381
statistics sampled from 17365 (17681) to 17365 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.558), E-opt: 0.2 (0.207), width: 16
Scan time: 8.120
The best scores are: opt bits E(85289)
XP_011526902 (OMIM: 600369) PREDICTED: cleavage st ( 431) 2889 427.5 3.3e-119
NP_001028694 (OMIM: 600369) cleavage stimulation f ( 431) 2889 427.5 3.3e-119
NP_001315 (OMIM: 600369) cleavage stimulation fact ( 431) 2889 427.5 3.3e-119
NP_001028693 (OMIM: 600369) cleavage stimulation f ( 431) 2889 427.5 3.3e-119
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 324 59.6 1.4e-08
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 324 59.6 1.4e-08
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 324 59.6 1.4e-08
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300) 267 51.4 3.7e-06
XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326) 267 51.4 3.9e-06
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 267 51.5 4.2e-06
XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321) 266 51.3 4.3e-06
XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374) 267 51.5 4.3e-06
NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 267 51.5 4.6e-06
NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369) 266 51.3 4.8e-06
XP_011531867 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 261 50.5 5.8e-06
XP_011531865 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 261 50.5 5.8e-06
XP_011531866 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 261 50.5 5.8e-06
NP_055317 (OMIM: 608330) pre-mRNA-processing facto ( 504) 261 50.7 9.8e-06
NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436) 244 48.3 4.8e-05
NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478) 244 48.3 5.1e-05
NP_620640 (OMIM: 601787) transcription initiation ( 745) 243 48.3 7.8e-05
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 241 48.0 8.6e-05
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 241 48.0 8.6e-05
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 241 48.0 8.6e-05
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 241 48.0 8.7e-05
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 241 48.0 8.8e-05
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 241 48.0 8.8e-05
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672) 241 48.0 8.8e-05
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675) 241 48.0 8.8e-05
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675) 241 48.0 8.8e-05
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675) 241 48.0 8.8e-05
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675) 241 48.0 8.8e-05
NP_008882 (OMIM: 601787) transcription initiation ( 800) 232 46.8 0.00024
NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 214 43.8 0.00075
XP_011527969 (OMIM: 601475) PREDICTED: periodic tr ( 734) 218 44.7 0.00092
NP_005040 (OMIM: 601475) periodic tryptophan prote ( 919) 218 44.8 0.0011
XP_005267076 (OMIM: 215100,266500,601757,614879) P ( 285) 209 43.1 0.0011
XP_016880191 (OMIM: 601545,607432) PREDICTED: plat ( 345) 210 43.3 0.0012
NP_000279 (OMIM: 215100,266500,601757,614879) pero ( 323) 209 43.1 0.0012
NP_000421 (OMIM: 601545,607432) platelet-activatin ( 410) 210 43.4 0.0013
XP_016880189 (OMIM: 601545,607432) PREDICTED: plat ( 410) 210 43.4 0.0013
XP_016880190 (OMIM: 601545,607432) PREDICTED: plat ( 410) 210 43.4 0.0013
XP_016880188 (OMIM: 601545,607432) PREDICTED: plat ( 410) 210 43.4 0.0013
XP_011522204 (OMIM: 601545,607432) PREDICTED: plat ( 428) 210 43.4 0.0014
XP_011522203 (OMIM: 601545,607432) PREDICTED: plat ( 428) 210 43.4 0.0014
XP_011522205 (OMIM: 601545,607432) PREDICTED: plat ( 428) 210 43.4 0.0014
NP_002066 (OMIM: 139130,145500,617024) guanine nuc ( 340) 196 41.3 0.0047
NP_037361 (OMIM: 602233) apoptotic protease-activa (1237) 205 43.1 0.0049
NP_863651 (OMIM: 602233) apoptotic protease-activa (1248) 205 43.1 0.0049
NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 194 40.9 0.005
>>XP_011526902 (OMIM: 600369) PREDICTED: cleavage stimul (431 aa)
initn: 2889 init1: 2889 opt: 2889 Z-score: 2261.2 bits: 427.5 E(85289): 3.3e-119
Smith-Waterman score: 2889; 100.0% identity (100.0% similar) in 431 aa overlap (1-431:1-431)
10 20 30 40 50 60
pF1KE4 MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 QLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 EKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 FNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFR
370 380 390 400 410 420
430
pF1KE4 ARFWYRRSTTD
:::::::::::
XP_011 ARFWYRRSTTD
430
>>NP_001028694 (OMIM: 600369) cleavage stimulation facto (431 aa)
initn: 2889 init1: 2889 opt: 2889 Z-score: 2261.2 bits: 427.5 E(85289): 3.3e-119
Smith-Waterman score: 2889; 100.0% identity (100.0% similar) in 431 aa overlap (1-431:1-431)
10 20 30 40 50 60
pF1KE4 MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 QLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 EKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 FNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFR
370 380 390 400 410 420
430
pF1KE4 ARFWYRRSTTD
:::::::::::
NP_001 ARFWYRRSTTD
430
>>NP_001315 (OMIM: 600369) cleavage stimulation factor s (431 aa)
initn: 2889 init1: 2889 opt: 2889 Z-score: 2261.2 bits: 427.5 E(85289): 3.3e-119
Smith-Waterman score: 2889; 100.0% identity (100.0% similar) in 431 aa overlap (1-431:1-431)
10 20 30 40 50 60
pF1KE4 MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 QLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 EKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 FNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFR
370 380 390 400 410 420
430
pF1KE4 ARFWYRRSTTD
:::::::::::
NP_001 ARFWYRRSTTD
430
>>NP_001028693 (OMIM: 600369) cleavage stimulation facto (431 aa)
initn: 2889 init1: 2889 opt: 2889 Z-score: 2261.2 bits: 427.5 E(85289): 3.3e-119
Smith-Waterman score: 2889; 100.0% identity (100.0% similar) in 431 aa overlap (1-431:1-431)
10 20 30 40 50 60
pF1KE4 MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 QLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 EKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 FNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFR
370 380 390 400 410 420
430
pF1KE4 ARFWYRRSTTD
:::::::::::
NP_001 ARFWYRRSTTD
430
>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta (334 aa)
initn: 278 init1: 110 opt: 324 Z-score: 275.1 bits: 59.6 E(85289): 1.4e-08
Smith-Waterman score: 324; 26.2% identity (60.0% similar) in 260 aa overlap (167-424:81-330)
140 150 160 170 180 190
pF1KE4 TERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYT
.:. : .. .:. ..:.:.: : :
XP_005 VKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKT
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE4 LKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCN
::..: :. . ...: ..... .:.:....:. :. ..:..:..: .:. .
XP_005 LKIWDVSSGKCLKTLK--GHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL-
120 130 140 150 160
260 270 280 290 300 310
pF1KE4 PQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSK
: :.: . .:..: .... :..: :: ..:: .:..:. :. :. : . ::
XP_005 PA--HSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTL-IDDDNPPVSFVKFSP
170 180 190 200 210 220
320 330 340 350 360 370
pF1KE4 NSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYVLLPDERTI
:.::::.. :.. :::. : :. : ::: . . : :. : .. .
XP_005 NGKYILAATLDNTLKLWDYSKGKCLKTYTG---HKNEKYCIFANFSVTGGKWIVSGSEDN
230 240 250 260 270 280
380 390 400 410 420 430
pF1KE4 SLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCS--DDFRARFWYRRSTTD
. :. .: : . :. ::...: . ::. . . . .: ..:
XP_005 LVYIWNLQTKEIVQKLQ-GHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
290 300 310 320 330
>>NP_438172 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 278 init1: 110 opt: 324 Z-score: 275.1 bits: 59.6 E(85289): 1.4e-08
Smith-Waterman score: 324; 26.2% identity (60.0% similar) in 260 aa overlap (167-424:81-330)
140 150 160 170 180 190
pF1KE4 TERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYT
.:. : .. .:. ..:.:.: : :
NP_438 VKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKT
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE4 LKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCN
::..: :. . ...: ..... .:.:....:. :. ..:..:..: .:. .
NP_438 LKIWDVSSGKCLKTLK--GHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL-
120 130 140 150 160
260 270 280 290 300 310
pF1KE4 PQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSK
: :.: . .:..: .... :..: :: ..:: .:..:. :. :. : . ::
NP_438 PA--HSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTL-IDDDNPPVSFVKFSP
170 180 190 200 210 220
320 330 340 350 360 370
pF1KE4 NSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYVLLPDERTI
:.::::.. :.. :::. : :. : ::: . . : :. : .. .
NP_438 NGKYILAATLDNTLKLWDYSKGKCLKTYTG---HKNEKYCIFANFSVTGGKWIVSGSEDN
230 240 250 260 270 280
380 390 400 410 420 430
pF1KE4 SLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCS--DDFRARFWYRRSTTD
. :. .: : . :. ::...: . ::. . . . .: ..:
NP_438 LVYIWNLQTKEIVQKLQ-GHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
290 300 310 320 330
>>NP_060058 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 278 init1: 110 opt: 324 Z-score: 275.1 bits: 59.6 E(85289): 1.4e-08
Smith-Waterman score: 324; 26.2% identity (60.0% similar) in 260 aa overlap (167-424:81-330)
140 150 160 170 180 190
pF1KE4 TERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYT
.:. : .. .:. ..:.:.: : :
NP_060 VKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKT
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE4 LKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCN
::..: :. . ...: ..... .:.:....:. :. ..:..:..: .:. .
NP_060 LKIWDVSSGKCLKTLK--GHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL-
120 130 140 150 160
260 270 280 290 300 310
pF1KE4 PQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSK
: :.: . .:..: .... :..: :: ..:: .:..:. :. :. : . ::
NP_060 PA--HSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTL-IDDDNPPVSFVKFSP
170 180 190 200 210 220
320 330 340 350 360 370
pF1KE4 NSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYVLLPDERTI
:.::::.. :.. :::. : :. : ::: . . : :. : .. .
NP_060 NGKYILAATLDNTLKLWDYSKGKCLKTYTG---HKNEKYCIFANFSVTGGKWIVSGSEDN
230 240 250 260 270 280
380 390 400 410 420 430
pF1KE4 SLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCS--DDFRARFWYRRSTTD
. :. .: : . :. ::...: . ::. . . . .: ..:
NP_060 LVYIWNLQTKEIVQKLQ-GHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
290 300 310 320 330
>>XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 cen (300 aa)
initn: 216 init1: 95 opt: 267 Z-score: 231.5 bits: 51.4 E(85289): 3.7e-06
Smith-Waterman score: 285; 24.4% identity (59.4% similar) in 303 aa overlap (44-327:5-292)
20 30 40 50 60 70
pF1KE4 LYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSD
:: . .: . .: : .. : :...:. .
XP_011 MAAPCAEDPSLERHFK-GHRDAVTCVDFSIN-TK
10 20 30
80 90 100 110 120 130
pF1KE4 TVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIK
.: :. .. : :.:.. :. :.:: ...: .:.:.:.:: : ...
XP_011 QLASGS---MDSCLMVWHMKPQSRAYR---FTGHKDAVTCVNFSPSGHLLASGSRDKTVR
40 50 60 70 80
140 150 160 170
pF1KE4 IL------DTERMLAKSAMPIEVMMNETAQQ--NMENHPVIR-----------TLYDHVD
: .. . :..: : . .:. . . ... .: .:..
XP_011 IWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHIN
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE4 EVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILV
: : : : ....:.: : :.::.: : : . . .: ... .. ..::::: : .
XP_011 WVRCAKFSPDGRLIVSASDDKTVKLWD--KSSRECVHSYCEHGGFVTYVDFHPSGTCIAA
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE4 GTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSN
. . :....:. : . . . . :. :. ..... :.:. .:.:.:. .:. : . .
XP_011 AGMDNTVKVWDVRTHRLL---QHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEG
210 220 230 240 250 260
300 310 320 330 340 350
pF1KE4 RCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQV
: . :.. .:.: . : ::....:. :.:.:
XP_011 RLLYTLH-GHQGPATTVA-FSRTGEYFASGGSDEQVICARP
270 280 290 300
360 370 380 390 400 410
pF1KE4 HRTQAVFNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMT
>>XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 cen (326 aa)
initn: 216 init1: 95 opt: 267 Z-score: 231.1 bits: 51.4 E(85289): 3.9e-06
Smith-Waterman score: 285; 24.4% identity (59.4% similar) in 303 aa overlap (44-327:5-292)
20 30 40 50 60 70
pF1KE4 LYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSD
:: . .: . .: : .. : :...:. .
XP_011 MAAPCAEDPSLERHFK-GHRDAVTCVDFSIN-TK
10 20 30
80 90 100 110 120 130
pF1KE4 TVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIK
.: :. .. : :.:.. :. :.:: ...: .:.:.:.:: : ...
XP_011 QLASGS---MDSCLMVWHMKPQSRAYR---FTGHKDAVTCVNFSPSGHLLASGSRDKTVR
40 50 60 70 80
140 150 160 170
pF1KE4 IL------DTERMLAKSAMPIEVMMNETAQQ--NMENHPVIR-----------TLYDHVD
: .. . :..: : . .:. . . ... .: .:..
XP_011 IWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHIN
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE4 EVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILV
: : : : ....:.: : :.::.: : : . . .: ... .. ..::::: : .
XP_011 WVRCAKFSPDGRLIVSASDDKTVKLWD--KSSRECVHSYCEHGGFVTYVDFHPSGTCIAA
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE4 GTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSN
. . :....:. : . . . . :. :. ..... :.:. .:.:.:. .:. : . .
XP_011 AGMDNTVKVWDVRTHRLL---QHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEG
210 220 230 240 250 260
300 310 320 330 340 350
pF1KE4 RCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQV
: . :.. .:.: . : ::....:. :.:.:
XP_011 RLLYTLH-GHQGPATTVA-FSRTGEYFASGGSDEQTVSILEQRLTLTEDKLKQCLENQQL
270 280 290 300 310
360 370 380 390 400 410
pF1KE4 HRTQAVFNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMT
XP_011 IMQRATP
320
>>NP_001155052 (OMIM: 614783,614813) POC1 centriolar pro (359 aa)
initn: 216 init1: 95 opt: 267 Z-score: 230.5 bits: 51.5 E(85289): 4.2e-06
Smith-Waterman score: 296; 24.2% identity (59.4% similar) in 310 aa overlap (44-334:5-299)
20 30 40 50 60 70
pF1KE4 LYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSD
:: . .: . .: : .. : :...:. .
NP_001 MAAPCAEDPSLERHFK-GHRDAVTCVDFSIN-TK
10 20 30
80 90 100 110 120 130
pF1KE4 TVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIK
.: :. .. : :.:.. :. :.:: ...: .:.:.:.:: : ...
NP_001 QLASGS---MDSCLMVWHMKPQSRAYR---FTGHKDAVTCVNFSPSGHLLASGSRDKTVR
40 50 60 70 80
140 150 160 170
pF1KE4 IL------DTERMLAKSAMPIEVMMNETAQQ--NMENHPVIR-----------TLYDHVD
: .. . :..: : . .:. . . ... .: .:..
NP_001 IWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHIN
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE4 EVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILV
: : : : ....:.: : :.::.: : : . . .: ... .. ..::::: : .
NP_001 WVRCAKFSPDGRLIVSASDDKTVKLWD--KSSRECVHSYCEHGGFVTYVDFHPSGTCIAA
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE4 GTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSN
. . :....:. : . . . . :. :. ..... :.:. .:.:.:. .:. : . .
NP_001 AGMDNTVKVWDVRTHRLL---QHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEG
210 220 230 240 250 260
300 310 320 330 340 350
pF1KE4 RCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQV
: . :.. .:.: . : ::....:. :.:.: . .:.
NP_001 RLLYTLH-GHQGPATTVA-FSRTGEYFASGGSDEQVMVWKSNFDIVDHGEVTKVPRPPAT
270 280 290 300 310
360 370 380 390 400 410
pF1KE4 HRTQAVFNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMT
NP_001 LASSMGNLTVSILEQRLTLTEDKLKQCLENQQLIMQRATP
320 330 340 350
431 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 00:42:50 2016 done: Sun Nov 6 00:42:51 2016
Total Scan time: 8.120 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]