FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4418, 431 aa
  1>>>pF1KE4418 431 - 431 aa - 431 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.2909+/-0.00136; mu= 6.5102+/- 0.079
 mean_var=123.9561+/-25.602, 0's: 0 Z-trim(102.7): 152  B-trim: 5 in 1/49
 Lambda= 0.115197
 statistics sampled from 6891 (7058) to 6891 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.572), E-opt: 0.2 (0.217), width:  16
 Scan time:  2.720

The best scores are:                                      opt bits E(32554)
CCDS13452.1 CSTF1 gene_id:1477|Hs108|chr20         ( 431) 2889 492.2  4e-139
CCDS3012.1 WDR5B gene_id:54554|Hs108|chr3          ( 330)  352 70.5 2.7e-12
CCDS6981.1 WDR5 gene_id:11091|Hs108|chr9           ( 334)  324 65.9 6.8e-11


>>CCDS13452.1 CSTF1 gene_id:1477|Hs108|chr20              (431 aa)
 initn: 2889 init1: 2889 opt: 2889  Z-score: 2611.2  bits: 492.2 E(32554): 4e-139
Smith-Waterman score: 2889; 100.0% identity (100.0% similar) in 431 aa overlap (1-431:1-431)

               10        20        30        40        50        60
pF1KE4 MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMEN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 DDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 DDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 QLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 QLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 FHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 FHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 LRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE4 EKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 EKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE4 FNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 FNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFR
              370       380       390       400       410       420

              430 
pF1KE4 ARFWYRRSTTD
       :::::::::::
CCDS13 ARFWYRRSTTD
              430 

>>CCDS3012.1 WDR5B gene_id:54554|Hs108|chr3               (330 aa)
 initn: 231 init1: 115 opt: 352  Z-score: 334.3  bits: 70.5 E(32554): 2.7e-12
Smith-Waterman score: 356; 26.0% identity (58.2% similar) in 311 aa overlap (116-424:31-326)

          90       100       110       120       130       140     
pF1KE4 DADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSA
                                     :.    :..   : .:.:.  . . ::.:.
CCDS30 MATKESRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSS
               10        20        30        40        50        60

         150       160       170       180       190       200     
pF1KE4 MPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKP
           ...  . . ..:     .::: :  :.. .:.    . :.:.: : ::::.:  . 
CCDS30 ADRLIIIWGAYDGKYE-----KTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSG
               70             80        90       100       110     

         210       220       230       240       250       260     
pF1KE4 SAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAI
       .  ...:   .....   .:.: ...:. :.   :.......: .:. . .    :.: .
CCDS30 KCLKTLK--GHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLS---AHSDPV
         120         130       140       150       160          170

         270       280       290       300       310       320     
pF1KE4 CSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSG
        .:..: :... :.:: ::  ..::..:..:. :.    :.  :  . :: :.::::.. 
CCDS30 SAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVD-DDNPPVSFVKFSPNGKYILTAT
              180       190       200        210       220         

         330       340       350       360       370       380     
pF1KE4 KDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYVLLPDERTISLCCWDSRT
        :.. :::. : :: :  :::       .    : :. :    ..   .   .  :. .:
CCDS30 LDNTLKLWDYSRGRCLKTYTGHKNEKYCIF---ANFSVTGGKWIVSGSEDNLVYIWNLQT
     230       240       250          260       270       280      

         390       400       410         420       430 
pF1KE4 AERRNLLSLGHNNIVRCIVHSPTNPGFMTCS--DDFRARFWYRRSTTD
        :  . :. ::...:   .  ::.  . . .  .:   ..:       
CCDS30 KEIVQKLQ-GHTDVVISAACHPTENLIASAALENDKTIKLWMSNH   
        290        300       310       320       330   

>>CCDS6981.1 WDR5 gene_id:11091|Hs108|chr9                (334 aa)
 initn: 278 init1: 110 opt: 324  Z-score: 309.0  bits: 65.9 E(32554): 6.8e-11
Smith-Waterman score: 324; 26.2% identity (60.0% similar) in 260 aa overlap (167-424:81-330)

        140       150       160       170       180       190      
pF1KE4 TERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYT
                                     .:.  :   .. .:.    ..:.:.: : :
CCDS69 VKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKT
               60        70        80        90       100       110

        200       210       220       230       240       250      
pF1KE4 LKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCN
       ::..: :. .  ...:   .....   .:.:....:. :.   ..:..:..: .:. .  
CCDS69 LKIWDVSSGKCLKTLK--GHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL-
              120         130       140       150       160        

        260       270       280       290       300       310      
pF1KE4 PQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSK
       :   :.: . .:..: .... :..: ::  ..:: .:..:. :.    :.  :  . :: 
CCDS69 PA--HSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTL-IDDDNPPVSFVKFSP
         170       180       190       200        210       220    

        320       330       340       350       360       370      
pF1KE4 NSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYVLLPDERTI
       :.::::..  :.. :::. : :. :  :::      . .   : :. :    ..   .  
CCDS69 NGKYILAATLDNTLKLWDYSKGKCLKTYTG---HKNEKYCIFANFSVTGGKWIVSGSEDN
          230       240       250          260       270       280 

        380       390       400       410         420       430 
pF1KE4 SLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCS--DDFRARFWYRRSTTD
        .  :. .: :  . :. ::...:   .  ::.  . . .  .:   ..:       
CCDS69 LVYIWNLQTKEIVQKLQ-GHTDVVISTACHPTENIIASAALENDKTIKLWKSDC   
             290        300       310       320       330       




431 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 00:42:49 2016 done: Sun Nov  6 00:42:49 2016
 Total Scan time:  2.720 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]