FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4417, 430 aa
  1>>>pF1KE4417 430 - 430 aa - 430 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2689+/-0.000376; mu= 17.1311+/- 0.023
 mean_var=65.2093+/-12.991, 0's: 0 Z-trim(112.7): 17  B-trim: 0 in 0/54
 Lambda= 0.158825
 statistics sampled from 21673 (21689) to 21673 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.254), width:  16
 Scan time:  8.620

The best scores are:                                      opt bits E(85289)
NP_002071 (OMIM: 138150) aspartate aminotransferas ( 430) 2889 671.0 1.6e-192
NP_001273149 (OMIM: 138150) aspartate aminotransfe ( 387) 2070 483.3 4.5e-136
NP_002070 (OMIM: 138180,614419) aspartate aminotra ( 413) 1324 312.4 1.4e-84


>>NP_002071 (OMIM: 138150) aspartate aminotransferase, m  (430 aa)
 initn: 2889 init1: 2889 opt: 2889  Z-score: 3577.5  bits: 671.0 E(85289): 1.6e-192
Smith-Waterman score: 2889; 99.8% identity (100.0% similar) in 430 aa overlap (1-430:1-430)

               10        20        30        40        50        60
pF1KE4 MALLHSGRVLPGIAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MALLHSGRVLPGIAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 NLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENSEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENSEV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 LKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAGMQLQGYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAGMQLQGYR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 YYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIATVVKKRNLFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIATVVKKRNLFA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 FFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTMVCKDADE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTMVCKDADE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE4 AKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIGMRTQLVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIGMRTQLVS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE4 NLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKEFSIYMTKDGRISVAGVTSSNVGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKEFSIYMTKDGRISVAGVTSSNVGY
              370       380       390       400       410       420

              430
pF1KE4 LAHAIHQATK
       :::::::.::
NP_002 LAHAIHQVTK
              430

>>NP_001273149 (OMIM: 138150) aspartate aminotransferase  (387 aa)
 initn: 2068 init1: 2068 opt: 2070  Z-score: 2564.0  bits: 483.3 E(85289): 4.5e-136
Smith-Waterman score: 2526; 89.8% identity (90.0% similar) in 430 aa overlap (1-430:1-387)

               10        20        30        40        50        60
pF1KE4 MALLHSGRVLPGIAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALLHSGRVLPGIAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 NLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENSEV
       ::::::::::::::::::::::                                      
NP_001 NLGVGAYRDDNGKPYVLPSVRK--------------------------------------
               70        80                                        

              130       140       150       160       170       180
pF1KE4 LKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAGMQLQGYR
            :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -----FVTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAGMQLQGYR
                  90       100       110       120       130       

              190       200       210       220       230       240
pF1KE4 YYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIATVVKKRNLFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIATVVKKRNLFA
       140       150       160       170       180       190       

              250       260       270       280       290       300
pF1KE4 FFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTMVCKDADE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTMVCKDADE
       200       210       220       230       240       250       

              310       320       330       340       350       360
pF1KE4 AKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIGMRTQLVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIGMRTQLVS
       260       270       280       290       300       310       

              370       380       390       400       410       420
pF1KE4 NLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKEFSIYMTKDGRISVAGVTSSNVGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKEFSIYMTKDGRISVAGVTSSNVGY
       320       330       340       350       360       370       

              430
pF1KE4 LAHAIHQATK
       :::::::.::
NP_001 LAHAIHQVTK
       380       

>>NP_002070 (OMIM: 138180,614419) aspartate aminotransfe  (413 aa)
 initn: 1298 init1: 919 opt: 1324  Z-score: 1639.7  bits: 312.4 E(85289): 1.4e-84
Smith-Waterman score: 1324; 48.8% identity (78.2% similar) in 404 aa overlap (31-428:5-408)

               10        20        30        40        50        60
pF1KE4 MALLHSGRVLPGIAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKM
                                     : ...: .. :  .. .:  :..: . .:.
NP_002                           MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKV
                                         10        20        30    

               70        80        90        100       110         
pF1KE4 NLGVGAYRDDNGKPYVLPSVRKAEAQIAAKN-LDKEYLPIGGLAEFCKASAELALGENSE
       :::::::: :. .:.::: :.:.: .::  : :..::::: ::::: . ...::::..: 
NP_002 NLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNHEYLPILGLAEFRSCASRLALGDDSP
           40        50        60        70        80        90    

     120       130       140       150           160       170     
pF1KE4 VLKSGRFVTVQTISGTGALRIGASFLQRFFKFSRD----VFLPKPTWGNHTPIFRDAGMQ
       .::  :   ::...:::::::::.:: :... . .    :.. .::: ::. .:  ::..
NP_002 ALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTPVYVSSPTWENHNAVFSAAGFK
          100       110       120       130       140       150    

          180       190       200       210       220       230    
pF1KE4 -LQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIATVVK
        ...:::.: .  :.:. : ..:. . :: :...::::::::::.:: :::::.::.:.:
NP_002 DIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIVVLHACAHNPTGIDPTPEQWKQIASVMK
          160       170       180       190       200       210    

          240       250       260       270       280       290    
pF1KE4 KRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTMV
       .: :: ::: ::::::::. ..::::.:.:. .:..    ::..::.:::.:::: .:.:
NP_002 HRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCAQSFSKNFGLYNERVGNLTVV
          220       230       240       250       260       270    

          300       310       320       330       340       350    
pF1KE4 CKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIGM
        :. .   .: ::.. ..:  .:::: .::::.:. :..:.: ..:  .::.:::::. :
NP_002 GKEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRILTM
          280       290       300       310       320       330    

          360       370       380       390       400       410    
pF1KE4 RTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKEFSIYMTKDGRISVAGVT
       :..: . :.   .  .:.::::::::: ::::.:.::: :..:  ::.  .:::.:.:.:
NP_002 RSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLT
          340       350       360       370       380       390    

          420       430   
pF1KE4 SSNVGYLAHAIHQATK   
       ..:. :.: .::.:     
NP_002 TKNLDYVATSIHEAVTKIQ
          400       410   




430 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 00:43:25 2016 done: Sun Nov  6 00:43:26 2016
 Total Scan time:  8.620 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]