Result of FASTA (omim) for
pFN21AE4416
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4416, 429 aa
1>>>pF1KE4416 429 - 429 aa - 429 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1500+/-0.000389; mu= 17.6723+/- 0.024
mean_var=63.6205+/-12.798, 0's: 0 Z-trim(111.6): 49 B-trim: 0 in 0/50
Lambda= 0.160796
statistics sampled from 20278 (20290) to 20278 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.61), E-opt: 0.2 (0.238), width: 16
Scan time: 5.880
The best scores are: opt bits E(85289)
NP_000160 (OMIM: 300644,301500) alpha-galactosidas ( 429) 3046 715.7 5.7e-206
XP_005261673 (OMIM: 104170,609241,609242) PREDICTE ( 411) 1282 306.4 8.5e-83
NP_000253 (OMIM: 104170,609241,609242) alpha-N-ace ( 411) 1282 306.4 8.5e-83
XP_005261672 (OMIM: 104170,609241,609242) PREDICTE ( 411) 1282 306.4 8.5e-83
>>NP_000160 (OMIM: 300644,301500) alpha-galactosidase A (429 aa)
initn: 3046 init1: 3046 opt: 3046 Z-score: 3818.7 bits: 715.7 E(85289): 5.7e-206
Smith-Waterman score: 3046; 100.0% identity (100.0% similar) in 429 aa overlap (1-429:1-429)
10 20 30 40 50 60
pF1KE4 MQLRNPELHLGCALALRFLALVSWDIPGARALDNGLARTPTMGWLHWERFMCNLDCQEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MQLRNPELHLGCALALRFLALVSWDIPGARALDNGLARTPTMGWLHWERFMCNLDCQEEP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFADWGVDLLKFDGCYCDSLENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFADWGVDLLKFDGCYCDSLENL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 ADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 SILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSNDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 RHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNFEVWERPLSGLAWAVAMINRQEIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNFEVWERPLSGLAWAVAMINRQEIG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 GPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLLQLENT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLLQLENT
370 380 390 400 410 420
pF1KE4 MQMSLKDLL
:::::::::
NP_000 MQMSLKDLL
>>XP_005261673 (OMIM: 104170,609241,609242) PREDICTED: a (411 aa)
initn: 1102 init1: 774 opt: 1282 Z-score: 1607.5 bits: 306.4 E(85289): 8.5e-83
Smith-Waterman score: 1282; 49.9% identity (72.9% similar) in 399 aa overlap (32-424:18-409)
10 20 30 40 50 60
pF1KE4 QLRNPELHLGCALALRFLALVSWDIPGARALDNGLARTPTMGWLHWERFMCNLDCQEEPD
::::: .:: :::: :::: ::..:.:.:
XP_005 MLLKTVLLLGHVAQVLMLDNGLLQTPPMGWLAWERFRCNINCDEDPK
10 20 30 40
70 80 90 100 110 120
pF1KE4 SCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLA
.::::.::::::. :...::.: :: :: :::::.. ::. :::. ::.:::::: ::
XP_005 NCISEQLFMEMADRMAQDGWRDMGYTYLNIDDCWIGG-RDASGRLMPDPKRFPHGIPFLA
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 NYVHSKGLKLGIYADVGNKTCAGFPGS-FGYYDIDAQTFADWGVDLLKFDGCYCDSLENL
.:::: :::::::::.:: :: :.::. . ::::::.: ::.::.:::. .. :.
XP_005 DYVHSLGLKLGIYADMGNFTCMGYPGTTLDKVVQDAQTFAEWKVDMLKLDGCF-STPEER
110 120 130 140 150 160
190 200 210 220 230
pF1KE4 ADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQ-KPNYTEIRQYCNHWRNFADIDDSWKSI
:.:: .:. ::: ::: :..:: :: : . . ::. . . :: :::. ::.::: :.
XP_005 AQGYPKMAAALNATGRPIAFSCSWPAYEGGLPPRVNYSLLADICNLWRNYDDIQDSWWSV
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE4 KSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSND
:::.: .:. . ::::: :::::::.::::::: .:. .:::::...::::.::.:
XP_005 LSILNWFVEHQDILQPVAGPGHWNDPDMLLIGNFGLSLEQSRAQMALWTVLAAPLLMSTD
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE4 LRHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNF-EVWERPLSGLAWAVAMIN-RQ
:: :: : .::. .: ::::::: :: .... .. ::. ::::. : :..... :
XP_005 LRTISAQNMDILQNPLMIKINQDPLGIQGRRIHKEKSLIEVYMRPLSNKASALVFFSCRT
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE4 EIGGPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLLQL
.. : : .:::. . . . .: . .. . . . :::.:.:. :
XP_005 DM--PYRYH---SSLGQLNFTGSVIYEAQDVYSGDIISGLRDETNFTVIINPSGVVMWYL
350 360 370 380 390 400
420
pF1KE4 E--NTMQMSLKDLL
....::
XP_005 YPIKNLEMSQQ
410
>>NP_000253 (OMIM: 104170,609241,609242) alpha-N-acetylg (411 aa)
initn: 1102 init1: 774 opt: 1282 Z-score: 1607.5 bits: 306.4 E(85289): 8.5e-83
Smith-Waterman score: 1282; 49.9% identity (72.9% similar) in 399 aa overlap (32-424:18-409)
10 20 30 40 50 60
pF1KE4 QLRNPELHLGCALALRFLALVSWDIPGARALDNGLARTPTMGWLHWERFMCNLDCQEEPD
::::: .:: :::: :::: ::..:.:.:
NP_000 MLLKTVLLLGHVAQVLMLDNGLLQTPPMGWLAWERFRCNINCDEDPK
10 20 30 40
70 80 90 100 110 120
pF1KE4 SCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLA
.::::.::::::. :...::.: :: :: :::::.. ::. :::. ::.:::::: ::
NP_000 NCISEQLFMEMADRMAQDGWRDMGYTYLNIDDCWIGG-RDASGRLMPDPKRFPHGIPFLA
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 NYVHSKGLKLGIYADVGNKTCAGFPGS-FGYYDIDAQTFADWGVDLLKFDGCYCDSLENL
.:::: :::::::::.:: :: :.::. . ::::::.: ::.::.:::. .. :.
NP_000 DYVHSLGLKLGIYADMGNFTCMGYPGTTLDKVVQDAQTFAEWKVDMLKLDGCF-STPEER
110 120 130 140 150 160
190 200 210 220 230
pF1KE4 ADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQ-KPNYTEIRQYCNHWRNFADIDDSWKSI
:.:: .:. ::: ::: :..:: :: : . . ::. . . :: :::. ::.::: :.
NP_000 AQGYPKMAAALNATGRPIAFSCSWPAYEGGLPPRVNYSLLADICNLWRNYDDIQDSWWSV
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE4 KSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSND
:::.: .:. . ::::: :::::::.::::::: .:. .:::::...::::.::.:
NP_000 LSILNWFVEHQDILQPVAGPGHWNDPDMLLIGNFGLSLEQSRAQMALWTVLAAPLLMSTD
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE4 LRHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNF-EVWERPLSGLAWAVAMIN-RQ
:: :: : .::. .: ::::::: :: .... .. ::. ::::. : :..... :
NP_000 LRTISAQNMDILQNPLMIKINQDPLGIQGRRIHKEKSLIEVYMRPLSNKASALVFFSCRT
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE4 EIGGPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLLQL
.. : : .:::. . . . .: . .. . . . :::.:.:. :
NP_000 DM--PYRYH---SSLGQLNFTGSVIYEAQDVYSGDIISGLRDETNFTVIINPSGVVMWYL
350 360 370 380 390 400
420
pF1KE4 E--NTMQMSLKDLL
....::
NP_000 YPIKNLEMSQQ
410
>>XP_005261672 (OMIM: 104170,609241,609242) PREDICTED: a (411 aa)
initn: 1102 init1: 774 opt: 1282 Z-score: 1607.5 bits: 306.4 E(85289): 8.5e-83
Smith-Waterman score: 1282; 49.9% identity (72.9% similar) in 399 aa overlap (32-424:18-409)
10 20 30 40 50 60
pF1KE4 QLRNPELHLGCALALRFLALVSWDIPGARALDNGLARTPTMGWLHWERFMCNLDCQEEPD
::::: .:: :::: :::: ::..:.:.:
XP_005 MLLKTVLLLGHVAQVLMLDNGLLQTPPMGWLAWERFRCNINCDEDPK
10 20 30 40
70 80 90 100 110 120
pF1KE4 SCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLA
.::::.::::::. :...::.: :: :: :::::.. ::. :::. ::.:::::: ::
XP_005 NCISEQLFMEMADRMAQDGWRDMGYTYLNIDDCWIGG-RDASGRLMPDPKRFPHGIPFLA
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 NYVHSKGLKLGIYADVGNKTCAGFPGS-FGYYDIDAQTFADWGVDLLKFDGCYCDSLENL
.:::: :::::::::.:: :: :.::. . ::::::.: ::.::.:::. .. :.
XP_005 DYVHSLGLKLGIYADMGNFTCMGYPGTTLDKVVQDAQTFAEWKVDMLKLDGCF-STPEER
110 120 130 140 150 160
190 200 210 220 230
pF1KE4 ADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQ-KPNYTEIRQYCNHWRNFADIDDSWKSI
:.:: .:. ::: ::: :..:: :: : . . ::. . . :: :::. ::.::: :.
XP_005 AQGYPKMAAALNATGRPIAFSCSWPAYEGGLPPRVNYSLLADICNLWRNYDDIQDSWWSV
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE4 KSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSND
:::.: .:. . ::::: :::::::.::::::: .:. .:::::...::::.::.:
XP_005 LSILNWFVEHQDILQPVAGPGHWNDPDMLLIGNFGLSLEQSRAQMALWTVLAAPLLMSTD
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE4 LRHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNF-EVWERPLSGLAWAVAMIN-RQ
:: :: : .::. .: ::::::: :: .... .. ::. ::::. : :..... :
XP_005 LRTISAQNMDILQNPLMIKINQDPLGIQGRRIHKEKSLIEVYMRPLSNKASALVFFSCRT
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE4 EIGGPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLLQL
.. : : .:::. . . . .: . .. . . . :::.:.:. :
XP_005 DM--PYRYH---SSLGQLNFTGSVIYEAQDVYSGDIISGLRDETNFTVIINPSGVVMWYL
350 360 370 380 390 400
420
pF1KE4 E--NTMQMSLKDLL
....::
XP_005 YPIKNLEMSQQ
410
429 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 01:14:59 2016 done: Sun Nov 6 01:15:00 2016
Total Scan time: 5.880 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]