Result of FASTA (omim) for
pFN21AE4370
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4370, 387 aa
1>>>pF1KE4370 387 - 387 aa - 387 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1163+/-0.000393; mu= 17.8393+/- 0.024
mean_var=70.4612+/-14.201, 0's: 0 Z-trim(112.5): 125 B-trim: 0 in 0/52
Lambda= 0.152792
statistics sampled from 21291 (21429) to 21291 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.621), E-opt: 0.2 (0.251), width: 16
Scan time: 8.460
The best scores are: opt bits E(85289)
NP_002144 (OMIM: 109685) estradiol 17-beta-dehydro ( 387) 2618 586.5 3.7e-167
NP_000187 (OMIM: 218030,614232) corticosteroid 11- ( 405) 836 193.7 6.7e-49
XP_016862498 (OMIM: 603063) PREDICTED: D-beta-hydr ( 324) 594 140.2 6.5e-33
XP_016862499 (OMIM: 603063) PREDICTED: D-beta-hydr ( 324) 594 140.2 6.5e-33
XP_016862501 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330) 594 140.3 6.6e-33
XP_016862500 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330) 594 140.3 6.6e-33
XP_016862497 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330) 594 140.3 6.6e-33
XP_005269409 (OMIM: 603063) PREDICTED: D-beta-hydr ( 343) 594 140.3 6.8e-33
XP_016862496 (OMIM: 603063) PREDICTED: D-beta-hydr ( 343) 594 140.3 6.8e-33
NP_976059 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343) 594 140.3 6.8e-33
NP_976060 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343) 594 140.3 6.8e-33
NP_004042 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343) 594 140.3 6.8e-33
XP_011511369 (OMIM: 603063) PREDICTED: D-beta-hydr ( 347) 594 140.3 6.8e-33
XP_011508777 (OMIM: 612131) PREDICTED: dehydrogena ( 319) 590 139.4 1.2e-32
NP_001135742 (OMIM: 612131) dehydrogenase/reductas ( 319) 590 139.4 1.2e-32
NP_001135743 (OMIM: 612131) dehydrogenase/reductas ( 319) 590 139.4 1.2e-32
NP_954674 (OMIM: 612131) dehydrogenase/reductase S ( 319) 590 139.4 1.2e-32
NP_001276692 (OMIM: 612131) dehydrogenase/reductas ( 379) 590 139.4 1.3e-32
NP_683695 (OMIM: 609769) short-chain dehydrogenase ( 313) 560 132.7 1.1e-30
XP_005269264 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 559 132.5 1.3e-30
NP_003716 (OMIM: 606623) 17-beta-hydroxysteroid de ( 317) 559 132.5 1.3e-30
XP_011537227 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 559 132.5 1.3e-30
XP_005269265 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 559 132.5 1.3e-30
XP_011537229 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 559 132.5 1.3e-30
XP_005269266 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 559 132.5 1.3e-30
XP_006719735 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 559 132.5 1.3e-30
XP_011537228 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 559 132.5 1.3e-30
NP_002896 (OMIM: 136880,601617) 11-cis retinol deh ( 318) 519 123.7 6e-28
NP_001186700 (OMIM: 136880,601617) 11-cis retinol ( 318) 519 123.7 6e-28
XP_005269412 (OMIM: 603063) PREDICTED: D-beta-hydr ( 206) 414 100.4 4e-21
XP_016862503 (OMIM: 603063) PREDICTED: D-beta-hydr ( 206) 414 100.4 4e-21
XP_016862504 (OMIM: 603063) PREDICTED: D-beta-hydr ( 206) 414 100.4 4e-21
NP_057330 (OMIM: 612832) 17-beta-hydroxysteroid de ( 270) 275 69.9 8.3e-12
XP_005256652 (OMIM: 616160) PREDICTED: dehydrogena ( 372) 254 65.3 2.6e-10
NP_001317088 (OMIM: 616160) dehydrogenase/reductas ( 310) 249 64.2 4.9e-10
NP_056325 (OMIM: 616160) dehydrogenase/reductase S ( 325) 249 64.2 5.1e-10
XP_016879915 (OMIM: 616160) PREDICTED: dehydrogena ( 325) 249 64.2 5.1e-10
XP_011522088 (OMIM: 616160) PREDICTED: dehydrogena ( 334) 249 64.2 5.2e-10
XP_016879914 (OMIM: 616160) PREDICTED: dehydrogena ( 372) 249 64.2 5.6e-10
XP_005259026 (OMIM: 612832) PREDICTED: 17-beta-hyd ( 212) 246 63.4 5.7e-10
NP_057113 (OMIM: 612833) dehydrogenase/reductase S ( 339) 245 63.3 9.7e-10
XP_016876857 (OMIM: 612833) PREDICTED: dehydrogena ( 404) 245 63.4 1.1e-09
NP_001309209 (OMIM: 612833) dehydrogenase/reductas ( 289) 229 59.8 9.8e-09
NP_835236 (OMIM: 612127) 17-beta-hydroxysteroid de ( 300) 204 54.3 4.6e-07
XP_016873370 (OMIM: 609574) PREDICTED: very-long-c ( 280) 195 52.2 1.7e-06
NP_057329 (OMIM: 612831) estradiol 17-beta-dehydro ( 300) 195 52.3 1.8e-06
NP_057226 (OMIM: 609574) very-long-chain 3-oxoacyl ( 312) 193 51.8 2.6e-06
XP_011516921 (OMIM: 264300,605573) PREDICTED: test ( 310) 192 51.6 3e-06
XP_011516920 (OMIM: 264300,605573) PREDICTED: test ( 310) 192 51.6 3e-06
XP_016870161 (OMIM: 264300,605573) PREDICTED: test ( 310) 192 51.6 3e-06
>>NP_002144 (OMIM: 109685) estradiol 17-beta-dehydrogena (387 aa)
initn: 2618 init1: 2618 opt: 2618 Z-score: 3122.1 bits: 586.5 E(85289): 3.7e-167
Smith-Waterman score: 2618; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387)
10 20 30 40 50 60
pF1KE4 MSTFFSDTAWICLAVPTVLCGTVFCKYKKSSGQLWSWMVCLAGLCAVCLLILSPFWGLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSTFFSDTAWICLAVPTVLCGTVFCKYKKSSGQLWSWMVCLAGLCAVCLLILSPFWGLIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 FSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 MFSSVMRLELSKWGIKVASIQPGGFLTNIAGTSDKWEKLEKDILDHLPAEVQEDYGQDYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MFSSVMRLELSKWGIKVASIQPGGFLTNIAGTSDKWEKLEKDILDHLPAEVQEDYGQDYI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LAQRNFLLLINSLASKDFSPVLRDIQHAILAKSPFAYYTPGKGAYLWICLAHYLPIGIYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LAQRNFLLLINSLASKDFSPVLRDIQHAILAKSPFAYYTPGKGAYLWICLAHYLPIGIYD
310 320 330 340 350 360
370 380
pF1KE4 YFAKRHFGQDKPMPRALRMPNYKKKAT
:::::::::::::::::::::::::::
NP_002 YFAKRHFGQDKPMPRALRMPNYKKKAT
370 380
>>NP_000187 (OMIM: 218030,614232) corticosteroid 11-beta (405 aa)
initn: 784 init1: 784 opt: 836 Z-score: 998.9 bits: 193.7 E(85289): 6.7e-49
Smith-Waterman score: 836; 39.4% identity (66.8% similar) in 373 aa overlap (6-378:8-377)
10 20 30 40 50
pF1KE4 MSTFFSDTAWICLAVPTVLCGTVFCKYKKSSGQLWSWMVCLAGLCAVCLLILSPFWGL
: ::. .:. ..: .. . . . : . .. ::.: .: .: : .:
NP_000 MERWPWPSGGAWLLVAARALL--QLLRSDLRLGRPLLAALALLAALDWLCQRLLPPPAAL
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 ILFSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENG
..... .. . :. . ::: .:::.:: : :.:. : :: .::::.: ::. :.
NP_000 AVLAAAGWIALSRLARPQRLPVATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 PGAEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGE
::: ::: ::::: .::::.::: .:. . . : . :::...:::: .:.:
NP_000 PGAIELRTCCSPRLRLLQMDLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 LLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAA
: .. ...:: :::::..:.:: .:::::.:.::.:.:.: .: :. :..::.::::
NP_000 LSPVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 VTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTSDKWEKLEKDILDHLPAEVQEDYGQD
:... ... :: ::.::. :::: : :. . . .::: .. .: .:: :. . ::.:
NP_000 VALLMDTFSCELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLPQELLQAYGKD
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 YILAQRNFLLLINSLASKDFSPVLRDIQHAILAKSPFAYYTPGKGAYLWICLAHYLPIGI
:: .. .: :: .:..::. : :.:: : : ::.: : . .::: :.
NP_000 YIEHLHGQFLHSLRLAMSDLTPVVDAITDALLAARPRRRYYPGQGLGLMYFIHYYLPEGL
300 310 320 330 340 350
360 370 380
pF1KE4 YDYFAKRHFGQDKPMPRALRMPNYKKKAT
: . : .. .::::.
NP_000 RRRFLQAFF-ISHCLPRALQPGQPGTTPPQDAAQDPNLSPGPSPAVAR
360 370 380 390 400
>>XP_016862498 (OMIM: 603063) PREDICTED: D-beta-hydroxyb (324 aa)
initn: 469 init1: 246 opt: 594 Z-score: 711.9 bits: 140.2 E(85289): 6.5e-33
Smith-Waterman score: 594; 36.0% identity (62.7% similar) in 303 aa overlap (70-365:26-324)
40 50 60 70 80 90
pF1KE4 CLAGLCAVCLLILSPFWGLILFSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALC
:: :. : :: .::::::: : :.: .:
XP_016 MASNGIQKRRPLLLGSTSFIPIGRRTYASAAE--PVGSKAVLVTGCDSGFGFSLA
10 20 30 40 50
100 110 120 130 140 150
pF1KE4 KYLDELGFTVFAGVL--NENGPGAEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQ
:.: :: :::: : ... :..:: : :: ..:... . ... . : . :.
XP_016 KHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLK
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE4 D--RGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLV
: .:.:...::::. : . :. . ::: ::..:::..::.::::.:..:::.:
XP_016 DPEKGMWGLVNNAGISTFG-EVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVV
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE4 NVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTS-D
:.::: : . : .: .: ::. .: :. :.::. ..::.:.. . : .
XP_016 NISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPE
180 190 200 210 220 230
280 290 300 310 320 330
pF1KE4 KWEKLEKDILDHLPAEVQEDYGQDYILAQRNFLLLINSLASKDFSPVLRDIQHAILAKSP
. . . : . ..:: :..:::. :. . . : .: : :::. . ::. : .:
XP_016 SIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTP
240 250 260 270 280 290
340 350 360 370 380
pF1KE4 FAYYTPGKGAYLWICLA--HYLPIGIYDYFAKRHFGQDKPMPRALRMPNYKKKAT
.. : : : :. . .:: .: :.. :
XP_016 YTRYHP-MDYYWWLRMQIMTHLPGAISDMIYIR
300 310 320
>>XP_016862499 (OMIM: 603063) PREDICTED: D-beta-hydroxyb (324 aa)
initn: 469 init1: 246 opt: 594 Z-score: 711.9 bits: 140.2 E(85289): 6.5e-33
Smith-Waterman score: 594; 36.0% identity (62.7% similar) in 303 aa overlap (70-365:26-324)
40 50 60 70 80 90
pF1KE4 CLAGLCAVCLLILSPFWGLILFSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALC
:: :. : :: .::::::: : :.: .:
XP_016 MASNGIQKRRPLLLGSTSFIPIGRRTYASAAE--PVGSKAVLVTGCDSGFGFSLA
10 20 30 40 50
100 110 120 130 140 150
pF1KE4 KYLDELGFTVFAGVL--NENGPGAEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQ
:.: :: :::: : ... :..:: : :: ..:... . ... . : . :.
XP_016 KHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLK
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE4 D--RGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLV
: .:.:...::::. : . :. . ::: ::..:::..::.::::.:..:::.:
XP_016 DPEKGMWGLVNNAGISTFG-EVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVV
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE4 NVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTS-D
:.::: : . : .: .: ::. .: :. :.::. ..::.:.. . : .
XP_016 NISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPE
180 190 200 210 220 230
280 290 300 310 320 330
pF1KE4 KWEKLEKDILDHLPAEVQEDYGQDYILAQRNFLLLINSLASKDFSPVLRDIQHAILAKSP
. . . : . ..:: :..:::. :. . . : .: : :::. . ::. : .:
XP_016 SIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTP
240 250 260 270 280 290
340 350 360 370 380
pF1KE4 FAYYTPGKGAYLWICLA--HYLPIGIYDYFAKRHFGQDKPMPRALRMPNYKKKAT
.. : : : :. . .:: .: :.. :
XP_016 YTRYHP-MDYYWWLRMQIMTHLPGAISDMIYIR
300 310 320
>>XP_016862501 (OMIM: 603063) PREDICTED: D-beta-hydroxyb (330 aa)
initn: 469 init1: 246 opt: 594 Z-score: 711.8 bits: 140.3 E(85289): 6.6e-33
Smith-Waterman score: 594; 36.0% identity (62.7% similar) in 303 aa overlap (70-365:32-330)
40 50 60 70 80 90
pF1KE4 CLAGLCAVCLLILSPFWGLILFSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALC
:: :. : :: .::::::: : :.: .:
XP_016 VIQFCKILPLGEMRRPLLLGSTSFIPIGRRTYASAAE--PVGSKAVLVTGCDSGFGFSLA
10 20 30 40 50
100 110 120 130 140 150
pF1KE4 KYLDELGFTVFAGVL--NENGPGAEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQ
:.: :: :::: : ... :..:: : :: ..:... . ... . : . :.
XP_016 KHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLK
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE4 D--RGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLV
: .:.:...::::. : . :. . ::: ::..:::..::.::::.:..:::.:
XP_016 DPEKGMWGLVNNAGISTFG-EVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVV
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE4 NVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTS-D
:.::: : . : .: .: ::. .: :. :.::. ..::.:.. . : .
XP_016 NISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPE
180 190 200 210 220 230
280 290 300 310 320 330
pF1KE4 KWEKLEKDILDHLPAEVQEDYGQDYILAQRNFLLLINSLASKDFSPVLRDIQHAILAKSP
. . . : . ..:: :..:::. :. . . : .: : :::. . ::. : .:
XP_016 SIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTP
240 250 260 270 280 290
340 350 360 370 380
pF1KE4 FAYYTPGKGAYLWICLA--HYLPIGIYDYFAKRHFGQDKPMPRALRMPNYKKKAT
.. : : : :. . .:: .: :.. :
XP_016 YTRYHP-MDYYWWLRMQIMTHLPGAISDMIYIR
300 310 320 330
>>XP_016862500 (OMIM: 603063) PREDICTED: D-beta-hydroxyb (330 aa)
initn: 469 init1: 246 opt: 594 Z-score: 711.8 bits: 140.3 E(85289): 6.6e-33
Smith-Waterman score: 594; 36.0% identity (62.7% similar) in 303 aa overlap (70-365:32-330)
40 50 60 70 80 90
pF1KE4 CLAGLCAVCLLILSPFWGLILFSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALC
:: :. : :: .::::::: : :.: .:
XP_016 VIQFCKILPLGEMRRPLLLGSTSFIPIGRRTYASAAE--PVGSKAVLVTGCDSGFGFSLA
10 20 30 40 50
100 110 120 130 140 150
pF1KE4 KYLDELGFTVFAGVL--NENGPGAEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQ
:.: :: :::: : ... :..:: : :: ..:... . ... . : . :.
XP_016 KHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLK
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE4 D--RGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLV
: .:.:...::::. : . :. . ::: ::..:::..::.::::.:..:::.:
XP_016 DPEKGMWGLVNNAGISTFG-EVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVV
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE4 NVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTS-D
:.::: : . : .: .: ::. .: :. :.::. ..::.:.. . : .
XP_016 NISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPE
180 190 200 210 220 230
280 290 300 310 320 330
pF1KE4 KWEKLEKDILDHLPAEVQEDYGQDYILAQRNFLLLINSLASKDFSPVLRDIQHAILAKSP
. . . : . ..:: :..:::. :. . . : .: : :::. . ::. : .:
XP_016 SIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTP
240 250 260 270 280 290
340 350 360 370 380
pF1KE4 FAYYTPGKGAYLWICLA--HYLPIGIYDYFAKRHFGQDKPMPRALRMPNYKKKAT
.. : : : :. . .:: .: :.. :
XP_016 YTRYHP-MDYYWWLRMQIMTHLPGAISDMIYIR
300 310 320 330
>>XP_016862497 (OMIM: 603063) PREDICTED: D-beta-hydroxyb (330 aa)
initn: 469 init1: 246 opt: 594 Z-score: 711.8 bits: 140.3 E(85289): 6.6e-33
Smith-Waterman score: 594; 36.0% identity (62.7% similar) in 303 aa overlap (70-365:32-330)
40 50 60 70 80 90
pF1KE4 CLAGLCAVCLLILSPFWGLILFSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALC
:: :. : :: .::::::: : :.: .:
XP_016 VIQFCKILPLGEMRRPLLLGSTSFIPIGRRTYASAAE--PVGSKAVLVTGCDSGFGFSLA
10 20 30 40 50
100 110 120 130 140 150
pF1KE4 KYLDELGFTVFAGVL--NENGPGAEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQ
:.: :: :::: : ... :..:: : :: ..:... . ... . : . :.
XP_016 KHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLK
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE4 D--RGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLV
: .:.:...::::. : . :. . ::: ::..:::..::.::::.:..:::.:
XP_016 DPEKGMWGLVNNAGISTFG-EVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVV
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE4 NVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTS-D
:.::: : . : .: .: ::. .: :. :.::. ..::.:.. . : .
XP_016 NISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPE
180 190 200 210 220 230
280 290 300 310 320 330
pF1KE4 KWEKLEKDILDHLPAEVQEDYGQDYILAQRNFLLLINSLASKDFSPVLRDIQHAILAKSP
. . . : . ..:: :..:::. :. . . : .: : :::. . ::. : .:
XP_016 SIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTP
240 250 260 270 280 290
340 350 360 370 380
pF1KE4 FAYYTPGKGAYLWICLA--HYLPIGIYDYFAKRHFGQDKPMPRALRMPNYKKKAT
.. : : : :. . .:: .: :.. :
XP_016 YTRYHP-MDYYWWLRMQIMTHLPGAISDMIYIR
300 310 320 330
>>XP_005269409 (OMIM: 603063) PREDICTED: D-beta-hydroxyb (343 aa)
initn: 469 init1: 246 opt: 594 Z-score: 711.6 bits: 140.3 E(85289): 6.8e-33
Smith-Waterman score: 594; 36.0% identity (62.7% similar) in 303 aa overlap (70-365:45-343)
40 50 60 70 80 90
pF1KE4 CLAGLCAVCLLILSPFWGLILFSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALC
:: :. : :: .::::::: : :.: .:
XP_005 GKTLSACDRENGARRPLLLGSTSFIPIGRRTYASAAE--PVGSKAVLVTGCDSGFGFSLA
20 30 40 50 60 70
100 110 120 130 140 150
pF1KE4 KYLDELGFTVFAGVL--NENGPGAEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQ
:.: :: :::: : ... :..:: : :: ..:... . ... . : . :.
XP_005 KHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLK
80 90 100 110 120 130
160 170 180 190 200 210
pF1KE4 D--RGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLV
: .:.:...::::. : . :. . ::: ::..:::..::.::::.:..:::.:
XP_005 DPEKGMWGLVNNAGISTFG-EVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVV
140 150 160 170 180 190
220 230 240 250 260 270
pF1KE4 NVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTS-D
:.::: : . : .: .: ::. .: :. :.::. ..::.:.. . : .
XP_005 NISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPE
200 210 220 230 240 250
280 290 300 310 320 330
pF1KE4 KWEKLEKDILDHLPAEVQEDYGQDYILAQRNFLLLINSLASKDFSPVLRDIQHAILAKSP
. . . : . ..:: :..:::. :. . . : .: : :::. . ::. : .:
XP_005 SIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTP
260 270 280 290 300 310
340 350 360 370 380
pF1KE4 FAYYTPGKGAYLWICLA--HYLPIGIYDYFAKRHFGQDKPMPRALRMPNYKKKAT
.. : : : :. . .:: .: :.. :
XP_005 YTRYHP-MDYYWWLRMQIMTHLPGAISDMIYIR
320 330 340
>>XP_016862496 (OMIM: 603063) PREDICTED: D-beta-hydroxyb (343 aa)
initn: 469 init1: 246 opt: 594 Z-score: 711.6 bits: 140.3 E(85289): 6.8e-33
Smith-Waterman score: 594; 36.0% identity (62.7% similar) in 303 aa overlap (70-365:45-343)
40 50 60 70 80 90
pF1KE4 CLAGLCAVCLLILSPFWGLILFSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALC
:: :. : :: .::::::: : :.: .:
XP_016 GKTLSACDRENGARRPLLLGSTSFIPIGRRTYASAAE--PVGSKAVLVTGCDSGFGFSLA
20 30 40 50 60 70
100 110 120 130 140 150
pF1KE4 KYLDELGFTVFAGVL--NENGPGAEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQ
:.: :: :::: : ... :..:: : :: ..:... . ... . : . :.
XP_016 KHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLK
80 90 100 110 120 130
160 170 180 190 200 210
pF1KE4 D--RGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLV
: .:.:...::::. : . :. . ::: ::..:::..::.::::.:..:::.:
XP_016 DPEKGMWGLVNNAGISTFG-EVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVV
140 150 160 170 180 190
220 230 240 250 260 270
pF1KE4 NVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTS-D
:.::: : . : .: .: ::. .: :. :.::. ..::.:.. . : .
XP_016 NISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPE
200 210 220 230 240 250
280 290 300 310 320 330
pF1KE4 KWEKLEKDILDHLPAEVQEDYGQDYILAQRNFLLLINSLASKDFSPVLRDIQHAILAKSP
. . . : . ..:: :..:::. :. . . : .: : :::. . ::. : .:
XP_016 SIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTP
260 270 280 290 300 310
340 350 360 370 380
pF1KE4 FAYYTPGKGAYLWICLA--HYLPIGIYDYFAKRHFGQDKPMPRALRMPNYKKKAT
.. : : : :. . .:: .: :.. :
XP_016 YTRYHP-MDYYWWLRMQIMTHLPGAISDMIYIR
320 330 340
>>NP_976059 (OMIM: 603063) D-beta-hydroxybutyrate dehydr (343 aa)
initn: 469 init1: 246 opt: 594 Z-score: 711.6 bits: 140.3 E(85289): 6.8e-33
Smith-Waterman score: 594; 36.0% identity (62.7% similar) in 303 aa overlap (70-365:45-343)
40 50 60 70 80 90
pF1KE4 CLAGLCAVCLLILSPFWGLILFSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALC
:: :. : :: .::::::: : :.: .:
NP_976 GKTLSACDRENGARRPLLLGSTSFIPIGRRTYASAAE--PVGSKAVLVTGCDSGFGFSLA
20 30 40 50 60 70
100 110 120 130 140 150
pF1KE4 KYLDELGFTVFAGVL--NENGPGAEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQ
:.: :: :::: : ... :..:: : :: ..:... . ... . : . :.
NP_976 KHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLK
80 90 100 110 120 130
160 170 180 190 200 210
pF1KE4 D--RGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLV
: .:.:...::::. : . :. . ::: ::..:::..::.::::.:..:::.:
NP_976 DPEKGMWGLVNNAGISTFG-EVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVV
140 150 160 170 180 190
220 230 240 250 260 270
pF1KE4 NVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTS-D
:.::: : . : .: .: ::. .: :. :.::. ..::.:.. . : .
NP_976 NISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPE
200 210 220 230 240 250
280 290 300 310 320 330
pF1KE4 KWEKLEKDILDHLPAEVQEDYGQDYILAQRNFLLLINSLASKDFSPVLRDIQHAILAKSP
. . . : . ..:: :..:::. :. . . : .: : :::. . ::. : .:
NP_976 SIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTP
260 270 280 290 300 310
340 350 360 370 380
pF1KE4 FAYYTPGKGAYLWICLA--HYLPIGIYDYFAKRHFGQDKPMPRALRMPNYKKKAT
.. : : : :. . .:: .: :.. :
NP_976 YTRYHP-MDYYWWLRMQIMTHLPGAISDMIYIR
320 330 340
387 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:07:08 2016 done: Sat Nov 5 23:07:10 2016
Total Scan time: 8.460 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]