Result of FASTA (omim) for
pFN21AE4369
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4369, 386 aa
1>>>pF1KE4369 386 - 386 aa - 386 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3267+/-0.000372; mu= 17.0574+/- 0.023
mean_var=69.0536+/-13.989, 0's: 0 Z-trim(113.7): 23 B-trim: 645 in 1/54
Lambda= 0.154341
statistics sampled from 23168 (23191) to 23168 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.272), width: 16
Scan time: 6.280
The best scores are: opt bits E(85289)
NP_001090 (OMIM: 171790) prostatic acid phosphatas ( 386) 2595 586.9 2.8e-167
XP_011511248 (OMIM: 171790) PREDICTED: prostatic a ( 387) 2560 579.1 6.2e-165
NP_001127666 (OMIM: 171790) prostatic acid phospha ( 418) 2550 576.9 3.1e-164
NP_001278966 (OMIM: 171790) prostatic acid phospha ( 353) 1357 311.2 2.5e-84
XP_011511249 (OMIM: 171790) PREDICTED: prostatic a ( 385) 1312 301.2 2.8e-81
NP_001601 (OMIM: 171650,200950) lysosomal acid pho ( 423) 1271 292.1 1.7e-78
NP_001289418 (OMIM: 171650,200950) lysosomal acid ( 395) 1233 283.6 5.6e-76
NP_001289419 (OMIM: 171650,200950) lysosomal acid ( 391) 1058 244.6 3e-64
NP_149059 (OMIM: 606362) testicular acid phosphata ( 426) 1007 233.3 8.3e-61
NP_001289421 (OMIM: 171650,200950) lysosomal acid ( 236) 621 147.2 3.8e-35
NP_001289420 (OMIM: 171650,200950) lysosomal acid ( 360) 574 136.8 7.7e-32
NP_057445 (OMIM: 611471) lysophosphatidic acid pho ( 428) 232 60.7 7.4e-09
XP_016856911 (OMIM: 611471) PREDICTED: lysophospha ( 386) 199 53.3 1.1e-06
XP_011507903 (OMIM: 611471) PREDICTED: lysophospha ( 401) 196 52.7 1.8e-06
NP_001310554 (OMIM: 611471) lysophosphatidic acid ( 403) 196 52.7 1.8e-06
>>NP_001090 (OMIM: 171790) prostatic acid phosphatase is (386 aa)
initn: 2595 init1: 2595 opt: 2595 Z-score: 3124.2 bits: 586.9 E(85289): 2.8e-167
Smith-Waterman score: 2595; 99.2% identity (99.5% similar) in 386 aa overlap (1-386:1-386)
10 20 30 40 50 60
pF1KE4 MRAAPLLLARAASLNLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AALVPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKR
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSRATEDTMTKLRELSE
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
NP_001 LHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 DVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELV
310 320 330 340 350 360
370 380
pF1KE4 GPVIPQDWSTECMTTNSHQGTEDSTD
::::::::::::::::::::::::::
NP_001 GPVIPQDWSTECMTTNSHQGTEDSTD
370 380
>>XP_011511248 (OMIM: 171790) PREDICTED: prostatic acid (387 aa)
initn: 2605 init1: 2560 opt: 2560 Z-score: 3082.1 bits: 579.1 E(85289): 6.2e-165
Smith-Waterman score: 2560; 99.0% identity (99.5% similar) in 381 aa overlap (1-381:1-381)
10 20 30 40 50 60
pF1KE4 MRAAPLLLARAASLNLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AALVPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKR
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSRATEDTMTKLRELSE
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_011 LHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 DVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELV
310 320 330 340 350 360
370 380
pF1KE4 GPVIPQDWSTECMTTNSHQGTEDSTD
::::::::::::::::::::.
XP_011 GPVIPQDWSTECMTTNSHQGSSFHIQY
370 380
>>NP_001127666 (OMIM: 171790) prostatic acid phosphatase (418 aa)
initn: 2550 init1: 2550 opt: 2550 Z-score: 3069.6 bits: 576.9 E(85289): 3.1e-164
Smith-Waterman score: 2550; 99.2% identity (99.5% similar) in 379 aa overlap (1-379:1-379)
10 20 30 40 50 60
pF1KE4 MRAAPLLLARAASLNLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AALVPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKR
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSRATEDTMTKLRELSE
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
NP_001 LHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 DVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELV
310 320 330 340 350 360
370 380
pF1KE4 GPVIPQDWSTECMTTNSHQGTEDSTD
:::::::::::::::::::
NP_001 GPVIPQDWSTECMTTNSHQVLKVIFAVAFCLISAVLMVLLFIHIRRGLCWQRESYGNI
370 380 390 400 410
>>NP_001278966 (OMIM: 171790) prostatic acid phosphatase (353 aa)
initn: 1357 init1: 1357 opt: 1357 Z-score: 1635.0 bits: 311.2 E(85289): 2.5e-84
Smith-Waterman score: 2291; 90.7% identity (90.9% similar) in 386 aa overlap (1-386:1-353)
10 20 30 40 50 60
pF1KE4 MRAAPLLLARAASLNLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AALVPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKR
::: ::::::::::::::::::::::::::::
NP_001 AALFPPEGVSIWNPILLWQPIPVHTVPLSEDQ----------------------------
130 140 150
190 200 210 220 230 240
pF1KE4 LHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSRATEDTMTKLRELSE
:::::::::::::::::::::::::::::::::::::::: ::::::::::::::
NP_001 -----DFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSE
160 170 180 190 200
250 260 270 280 290 300
pF1KE4 LSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMAL
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE4 DVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELV
270 280 290 300 310 320
370 380
pF1KE4 GPVIPQDWSTECMTTNSHQGTEDSTD
::::::::::::::::::::::::::
NP_001 GPVIPQDWSTECMTTNSHQGTEDSTD
330 340 350
>>XP_011511249 (OMIM: 171790) PREDICTED: prostatic acid (385 aa)
initn: 1312 init1: 1312 opt: 1312 Z-score: 1580.3 bits: 301.2 E(85289): 2.8e-81
Smith-Waterman score: 2246; 90.5% identity (90.8% similar) in 379 aa overlap (1-379:1-346)
10 20 30 40 50 60
pF1KE4 MRAAPLLLARAASLNLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 AALVPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKR
::: ::::::::::::::::::::::::::::
XP_011 AALFPPEGVSIWNPILLWQPIPVHTVPLSEDQ----------------------------
130 140 150
190 200 210 220 230 240
pF1KE4 LHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSRATEDTMTKLRELSE
:::::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_011 -----DFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSE
160 170 180 190 200
250 260 270 280 290 300
pF1KE4 LSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMAL
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE4 DVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELV
270 280 290 300 310 320
370 380
pF1KE4 GPVIPQDWSTECMTTNSHQGTEDSTD
:::::::::::::::::::
XP_011 GPVIPQDWSTECMTTNSHQVLKVIFAVAFCLISAVLMVLLFIHIRRGLCWQRESYGNI
330 340 350 360 370 380
>>NP_001601 (OMIM: 171650,200950) lysosomal acid phospha (423 aa)
initn: 830 init1: 830 opt: 1271 Z-score: 1530.4 bits: 292.1 E(85289): 1.7e-78
Smith-Waterman score: 1271; 51.5% identity (78.0% similar) in 355 aa overlap (32-382:30-380)
10 20 30 40 50 60
pF1KE4 RAAPLLLARAASLNLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKES
:. :.::::..:::::::. :.: :: .:
NP_001 MAGKRSGWSRAALLQLLLGVNLVVMPPTRARSLRFVTLLYRHGDRSPVKTYPKDPYQEE
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 SWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNLA
:::::::::. :: ::.:::. .:.::. ::: ::....::.:::: ::::::: .:::
NP_001 EWPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 ALVPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKRL
.: ::.:.. .:: . ::::::::::..::.:: .:. :::...:..:: .. :.:..
NP_001 GLFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNES
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 HPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSRATEDTMTKLRELSEL
.:. ... .:: : .:. ::: :.::..:.. :: :. .:: .: .:...
NP_001 SRNAQFLDMVANETGLTDLTLETVWN-VYDTLFCEQTHGLRLPPWASPQTMQRLSRLKDF
180 190 200 210 220 230
250 260 270 280 290
pF1KE4 SLLSLYGIHKQKEKSRLQGGVLVNEI---LNHMKRATQIPSYKKLIMYSAHDTTVSGLQM
:. :.::..: ::.:::::::. .: :. : ..:.: ::..:::::::. .:::
NP_001 SFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLP---KLLVYSAHDTTLVALQM
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 ALDVYNGLLPPYASCHLTELYFE-KGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFA
::::::: ::::::. ::: : .:.. ::::.:::... :.:: :::: :::. :
NP_001 ALDVYNGEQAPYASCHIFELYQEDSGNFSVEMYFRNESDKAPWPLSLPGCPHRCPLQDFL
300 310 320 330 340 350
360 370 380
pF1KE4 ELVGPVIPQDWSTECMTTNSHQGTEDSTD
.:. ::.:.::. ::. ... ::
NP_001 RLTEPVVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLFRMQAQPPGYRH
360 370 380 390 400 410
>>NP_001289418 (OMIM: 171650,200950) lysosomal acid phos (395 aa)
initn: 792 init1: 792 opt: 1233 Z-score: 1485.1 bits: 283.6 E(85289): 5.6e-76
Smith-Waterman score: 1233; 51.2% identity (77.7% similar) in 346 aa overlap (41-382:11-352)
20 30 40 50 60 70
pF1KE4 AASLNLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQL
..:::::::. :.: :: .: ::::::::
NP_001 MGVRMTEYVGLYRHGDRSPVKTYPKDPYQEEEWPQGFGQL
10 20 30 40
80 90 100 110 120 130
pF1KE4 TQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALVPPEGVS
:. :: ::.:::. .:.::. ::: ::....::.:::: ::::::: .:::.: ::.:..
NP_001 TKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAGLFPPNGMQ
50 60 70 80 90 100
140 150 160 170 180 190
pF1KE4 IWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIAT
.:: . ::::::::::..::.:: .:. :::...:..:: .. :.:.. .:.
NP_001 RFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNESSRNAQFLDM
110 120 130 140 150 160
200 210 220 230 240 250
pF1KE4 LGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSRATEDTMTKLRELSELSLLSLYGIH
... .:: : .:. ::: :.::..:.. :: :. .:: .: .:...:. :.::.
NP_001 VANETGLTDLTLETVWN-VYDTLFCEQTHGLRLPPWASPQTMQRLSRLKDFSFRFLFGIY
170 180 190 200 210
260 270 280 290 300
pF1KE4 KQKEKSRLQGGVLVNEI---LNHMKRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNGLL
.: ::.:::::::. .: :. : ..:.: ::..:::::::. .::::::::::
NP_001 QQAEKARLQGGVLLAQIRKNLTLMATTSQLP---KLLVYSAHDTTLVALQMALDVYNGEQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE4 PPYASCHLTELYFE-KGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQ
::::::. ::: : .:.. ::::.:::... :.:: :::: :::. : .:. ::.:.
NP_001 APYASCHIFELYQEDSGNFSVEMYFRNESDKAPWPLSLPGCPHRCPLQDFLRLTEPVVPK
280 290 300 310 320 330
370 380
pF1KE4 DWSTECMTTNSHQGTEDSTD
::. ::. ... ::
NP_001 DWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLFRMQAQPPGYRHVADGEDHA
340 350 360 370 380 390
>>NP_001289419 (OMIM: 171650,200950) lysosomal acid phos (391 aa)
initn: 616 init1: 616 opt: 1058 Z-score: 1274.6 bits: 244.6 E(85289): 3e-64
Smith-Waterman score: 1058; 49.5% identity (77.0% similar) in 317 aa overlap (70-382:36-348)
40 50 60 70 80 90
pF1KE4 LVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKH
.: :: ::.:::. .:.::. ::: ::..
NP_001 SGWSRAALLQLLLGVNLVVMPPTRARSLRFVTLEGMLQHWELGQALRQRYHGFLNTSYHR
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE4 EQVYIRSTDVDRTLMSAMTNLAALVPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFR
..::.:::: ::::::: .:::.: ::.:.. .:: . ::::::::::..::.:: .:.
NP_001 QEVYVRSTDFDRTLMSAEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLG
70 80 90 100 110 120
160 170 180 190 200 210
pF1KE4 NCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVH
:::...:..:: .. :.:.. .:. ... .:: : .:. ::: :.::..:
NP_001 PCPRYEQLQNETRQTPEYQNESSRNAQFLDMVANETGLTDLTLETVWN-VYDTLFCEQTH
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE4 NFTLPSRATEDTMTKLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEI---LNHMKRATQ
.. :: :. .:: .: .:...:. :.::..: ::.:::::::. .: :. : ..:
NP_001 GLRLPPWASPQTMQRLSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQ
190 200 210 220 230 240
280 290 300 310 320 330
pF1KE4 IPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFE-KGEYFVEMYYRNET
.: ::..:::::::. .:::::::::: ::::::. ::: : .:.. ::::.:::.
NP_001 LP---KLLVYSAHDTTLVALQMALDVYNGEQAPYASCHIFELYQEDSGNFSVEMYFRNES
250 260 270 280 290 300
340 350 360 370 380
pF1KE4 QHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD
.. :.:: :::: :::. : .:. ::.:.::. ::. ... ::
NP_001 DKAPWPLSLPGCPHRCPLQDFLRLTEPVVPKDWQQECQLASGPADTEVIVALAVCGSILF
310 320 330 340 350 360
NP_001 LLIVLLLTVLFRMQAQPPGYRHVADGEDHA
370 380 390
>>NP_149059 (OMIM: 606362) testicular acid phosphatase p (426 aa)
initn: 945 init1: 289 opt: 1007 Z-score: 1212.6 bits: 233.3 E(85289): 8.3e-61
Smith-Waterman score: 1007; 42.8% identity (70.0% similar) in 367 aa overlap (18-372:15-378)
10 20 30 40 50 60
pF1KE4 MRAAPLLLARAASLNLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE
.:.::. :.. : ::.::::::::.:. ..: :: ::
NP_149 MAGLGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKE
10 20 30 40 50
70 80 90 100 110
pF1KE4 SS---WPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAM
. ::.:.:::: :..:. :::...:.::. ::. :..:.::::::: :::: ::.
NP_149 VASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 TNLAALVPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEF
.:::.: : . . .: :.::::::::..::.:: .:.:.:::..:: :. .. :.
NP_149 ANLAGLFPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 QKRLHPYKDFIATLGKLSGLH--GQDLFGIWSKVYDPLYCESVHNFTLPSRATEDTMTKL
:. :. . :.. : ...:: :. : : :: : :.:...:.. ::. :. :.. :
NP_149 QEALEGWTGFLSRLENFTGLSLVGEPLRRAW-KVLDTLMCQQAHGLPLPAWASPDVLRTL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 RELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSG
..: :.. . : . ::..: ::.:.: :: ...:. .. :..::::::.:. .
NP_149 AQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLA
240 250 260 270 280 290
300 310 320 330 340
pF1KE4 LQMALDVYNGLLPPYASC-------HLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCS
:: :: .:.: ::::.: :: . . :. : ..:::.. : : :: ::::
NP_149 LQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCP
300 310 320 330 340 350
350 360 370 380
pF1KE4 PSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD
::: :: .:..:. : .. :
NP_149 APCPLGRFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAW
360 370 380 390 400 410
>>NP_001289421 (OMIM: 171650,200950) lysosomal acid phos (236 aa)
initn: 622 init1: 379 opt: 621 Z-score: 751.9 bits: 147.2 E(85289): 3.8e-35
Smith-Waterman score: 621; 49.5% identity (75.0% similar) in 192 aa overlap (195-382:6-193)
170 180 190 200 210 220
pF1KE4 QELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLP
.:: : .:. ::: :.::..:.. ::
NP_001 MVANETGLTDLTLETVWN-VYDTLFCEQTHGLRLP
10 20 30
230 240 250 260 270 280
pF1KE4 SRATEDTMTKLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEI---LNHMKRATQIPSYK
:. .:: .: .:...:. :.::..: ::.:::::::. .: :. : ..:.:
NP_001 PWASPQTMQRLSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLP---
40 50 60 70 80 90
290 300 310 320 330 340
pF1KE4 KLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFE-KGEYFVEMYYRNETQHEPY
::..:::::::. .:::::::::: ::::::. ::: : .:.. ::::.:::... :.
NP_001 KLLVYSAHDTTLVALQMALDVYNGEQAPYASCHIFELYQEDSGNFSVEMYFRNESDKAPW
100 110 120 130 140 150
350 360 370 380
pF1KE4 PLMLPGCSPSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD
:: :::: :::. : .:. ::.:.::. ::. ... ::
NP_001 PLSLPGCPHRCPLQDFLRLTEPVVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVL
160 170 180 190 200 210
NP_001 LLTVLFRMQAQPPGYRHVADGEDHA
220 230
386 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 19:03:23 2016 done: Mon Nov 7 19:03:24 2016
Total Scan time: 6.280 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]