Result of FASTA (omim) for
pFN21AE4363
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4363, 381 aa
1>>>pF1KE4363 381 - 381 aa - 381 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9628+/-0.000312; mu= 15.6184+/- 0.019
mean_var=113.1730+/-23.204, 0's: 0 Z-trim(119.7): 11 B-trim: 541 in 1/54
Lambda= 0.120560
statistics sampled from 34061 (34072) to 34061 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.755), E-opt: 0.2 (0.399), width: 16
Scan time: 8.470
The best scores are: opt bits E(85289)
XP_016860191 (OMIM: 178640,265120) PREDICTED: pulm ( 393) 2721 483.7 3.1e-136
XP_005264544 (OMIM: 178640,265120) PREDICTED: pulm ( 393) 2721 483.7 3.1e-136
NP_000533 (OMIM: 178640,265120) pulmonary surfacta ( 393) 2721 483.7 3.1e-136
NP_942140 (OMIM: 178640,265120) pulmonary surfacta ( 393) 2721 483.7 3.1e-136
XP_016860192 (OMIM: 178640,265120) PREDICTED: pulm ( 377) 2675 475.7 7.8e-134
XP_005264545 (OMIM: 178640,265120) PREDICTED: pulm ( 377) 2675 475.7 7.8e-134
XP_005264547 (OMIM: 178640,265120) PREDICTED: pulm ( 339) 2375 423.5 3.7e-118
>>XP_016860191 (OMIM: 178640,265120) PREDICTED: pulmonar (393 aa)
initn: 2721 init1: 2721 opt: 2721 Z-score: 2566.7 bits: 483.7 E(85289): 3.1e-136
Smith-Waterman score: 2721; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:13-393)
10 20 30 40
pF1KE4 MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQ
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MHQAGYPGCRGAMAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 CRALGHCLQEVWGHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRALGHCLQEVWGHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 MPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 PDPLLDKLVLPVLPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDPLLDKLVLPVLPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALA
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 VAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSP
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 TGEWLPRDSECHLCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGEWLPRDSECHLCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLT
310 320 330 340 350 360
350 360 370 380
pF1KE4 LVPRGWDAHTTCQALGVCGTMSSPLQCIHSPDL
:::::::::::::::::::::::::::::::::
XP_016 LVPRGWDAHTTCQALGVCGTMSSPLQCIHSPDL
370 380 390
>>XP_005264544 (OMIM: 178640,265120) PREDICTED: pulmonar (393 aa)
initn: 2721 init1: 2721 opt: 2721 Z-score: 2566.7 bits: 483.7 E(85289): 3.1e-136
Smith-Waterman score: 2721; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:13-393)
10 20 30 40
pF1KE4 MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQ
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MHQAGYPGCRGAMAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 CRALGHCLQEVWGHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CRALGHCLQEVWGHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 MPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 PDPLLDKLVLPVLPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDPLLDKLVLPVLPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALA
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 VAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSP
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 TGEWLPRDSECHLCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGEWLPRDSECHLCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLT
310 320 330 340 350 360
350 360 370 380
pF1KE4 LVPRGWDAHTTCQALGVCGTMSSPLQCIHSPDL
:::::::::::::::::::::::::::::::::
XP_005 LVPRGWDAHTTCQALGVCGTMSSPLQCIHSPDL
370 380 390
>>NP_000533 (OMIM: 178640,265120) pulmonary surfactant-a (393 aa)
initn: 2721 init1: 2721 opt: 2721 Z-score: 2566.7 bits: 483.7 E(85289): 3.1e-136
Smith-Waterman score: 2721; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:13-393)
10 20 30 40
pF1KE4 MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQ
::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MHQAGYPGCRGAMAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 CRALGHCLQEVWGHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CRALGHCLQEVWGHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 MPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 PDPLLDKLVLPVLPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PDPLLDKLVLPVLPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALA
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 VAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSP
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 TGEWLPRDSECHLCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TGEWLPRDSECHLCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLT
310 320 330 340 350 360
350 360 370 380
pF1KE4 LVPRGWDAHTTCQALGVCGTMSSPLQCIHSPDL
:::::::::::::::::::::::::::::::::
NP_000 LVPRGWDAHTTCQALGVCGTMSSPLQCIHSPDL
370 380 390
>>NP_942140 (OMIM: 178640,265120) pulmonary surfactant-a (393 aa)
initn: 2721 init1: 2721 opt: 2721 Z-score: 2566.7 bits: 483.7 E(85289): 3.1e-136
Smith-Waterman score: 2721; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:13-393)
10 20 30 40
pF1KE4 MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQ
::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MHQAGYPGCRGAMAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 CRALGHCLQEVWGHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 CRALGHCLQEVWGHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 MPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 PDPLLDKLVLPVLPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 PDPLLDKLVLPVLPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALA
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 VAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSP
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE4 TGEWLPRDSECHLCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 TGEWLPRDSECHLCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLT
310 320 330 340 350 360
350 360 370 380
pF1KE4 LVPRGWDAHTTCQALGVCGTMSSPLQCIHSPDL
:::::::::::::::::::::::::::::::::
NP_942 LVPRGWDAHTTCQALGVCGTMSSPLQCIHSPDL
370 380 390
>>XP_016860192 (OMIM: 178640,265120) PREDICTED: pulmonar (377 aa)
initn: 2033 init1: 2033 opt: 2675 Z-score: 2523.7 bits: 475.7 E(85289): 7.8e-134
Smith-Waterman score: 2675; 99.0% identity (99.0% similar) in 381 aa overlap (1-381:1-377)
10 20 30 40 50 60
pF1KE4 MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALAVAVAQVCRVVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALAVAVAQVCRVVPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 VAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECH
:::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 VAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPR----EWLPRDSECH
250 260 270 280 290
310 320 330 340 350 360
pF1KE4 LCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTC
300 310 320 330 340 350
370 380
pF1KE4 QALGVCGTMSSPLQCIHSPDL
:::::::::::::::::::::
XP_016 QALGVCGTMSSPLQCIHSPDL
360 370
>>XP_005264545 (OMIM: 178640,265120) PREDICTED: pulmonar (377 aa)
initn: 2033 init1: 2033 opt: 2675 Z-score: 2523.7 bits: 475.7 E(85289): 7.8e-134
Smith-Waterman score: 2675; 99.0% identity (99.0% similar) in 381 aa overlap (1-381:1-377)
10 20 30 40 50 60
pF1KE4 MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALAVAVAQVCRVVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALAVAVAQVCRVVPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 VAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECH
:::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_005 VAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPR----EWLPRDSECH
250 260 270 280 290
310 320 330 340 350 360
pF1KE4 LCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTC
300 310 320 330 340 350
370 380
pF1KE4 QALGVCGTMSSPLQCIHSPDL
:::::::::::::::::::::
XP_005 QALGVCGTMSSPLQCIHSPDL
360 370
>>XP_005264547 (OMIM: 178640,265120) PREDICTED: pulmonar (339 aa)
initn: 2375 init1: 2375 opt: 2375 Z-score: 2242.3 bits: 423.5 E(85289): 3.7e-118
Smith-Waterman score: 2375; 100.0% identity (100.0% similar) in 334 aa overlap (1-334:1-334)
10 20 30 40 50 60
pF1KE4 MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALAVAVAQVCRVVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALAVAVAQVCRVVPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 VAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTC
::::::::::::::::::::::::::::::::::
XP_005 LCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKLAPVC
310 320 330
370 380
pF1KE4 QALGVCGTMSSPLQCIHSPDL
381 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 02:03:23 2016 done: Sun Nov 6 02:03:24 2016
Total Scan time: 8.470 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]