Result of FASTA (ccds) for
pFN21AE4355
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4355, 372 aa
1>>>pF1KE4355 372 - 372 aa - 372 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2720+/-0.000877; mu= 16.4192+/- 0.053
mean_var=58.0853+/-11.592, 0's: 0 Z-trim(104.7): 17 B-trim: 6 in 1/49
Lambda= 0.168283
statistics sampled from 8003 (8013) to 8003 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.626), E-opt: 0.2 (0.246), width: 16
Scan time: 2.680
The best scores are: opt bits E(32554)
CCDS902.1 HSD3B2 gene_id:3284|Hs108|chr1 ( 372) 2463 606.3 1.3e-173
CCDS903.1 HSD3B1 gene_id:3283|Hs108|chr1 ( 373) 2337 575.8 2.2e-164
CCDS10698.1 HSD3B7 gene_id:80270|Hs108|chr16 ( 369) 820 207.5 1.6e-53
CCDS42205.1 SDR42E1 gene_id:93517|Hs108|chr16 ( 393) 462 120.5 2.5e-27
CCDS45466.1 HSD3B7 gene_id:80270|Hs108|chr16 ( 196) 396 104.4 8.8e-23
CCDS14717.1 NSDHL gene_id:50814|Hs108|chrX ( 373) 303 81.9 9.8e-16
>>CCDS902.1 HSD3B2 gene_id:3284|Hs108|chr1 (372 aa)
initn: 2463 init1: 2463 opt: 2463 Z-score: 3230.1 bits: 606.3 E(32554): 1.3e-173
Smith-Waterman score: 2463; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372)
10 20 30 40 50 60
pF1KE4 MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 DILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 YTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 YTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 TCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 TCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 DPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 DPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 SFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 SFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLV
310 320 330 340 350 360
370
pF1KE4 DRHKETLKSKTQ
::::::::::::
CCDS90 DRHKETLKSKTQ
370
>>CCDS903.1 HSD3B1 gene_id:3283|Hs108|chr1 (373 aa)
initn: 2337 init1: 2337 opt: 2337 Z-score: 3064.8 bits: 575.8 E(32554): 2.2e-164
Smith-Waterman score: 2337; 93.8% identity (98.1% similar) in 371 aa overlap (2-372:3-373)
10 20 30 40 50
pF1KE4 MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLE
:::::::::::.:::::.::::.::::::::.::::: ::::::::::::.:::::::
CCDS90 MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 GDILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVF
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
CCDS90 GDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 IYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTL
::::::::::::::::::::::::::::::::.:::.:::::::::::::::::::: ::
CCDS90 IYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 YTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRAL
::::::: ::::::. ::::::::::::::::::::::::::::::::::::::::::::
CCDS90 YTCALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRAL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 RDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEV
.:::::::.::::::::::::::::::::: ::::::::::::::.::.::::::::::.
CCDS90 QDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 VSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSL
::::: :::.:.:::::: :::::::::::::::::::::::::::::::::::::::::
CCDS90 VSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSL
310 320 330 340 350 360
360 370
pF1KE4 VDRHKETLKSKTQ
:::::::::::::
CCDS90 VDRHKETLKSKTQ
370
>>CCDS10698.1 HSD3B7 gene_id:80270|Hs108|chr16 (369 aa)
initn: 583 init1: 525 opt: 820 Z-score: 1074.4 bits: 207.5 E(32554): 1.6e-53
Smith-Waterman score: 820; 40.4% identity (69.5% similar) in 354 aa overlap (6-356:13-361)
10 20 30 40 50
pF1KE4 MGWSCLVTGAGGLLGQRIVRLLVE-EKELKEIRALDKAFRPELREEFSKLQNR
::::. :.::...::.:.. : .: :.:..:. . : : ::.. .
CCDS10 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWL-EELKT--GP
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 TKLTVLEGDILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACV
...:...::. . . : . :::::: ..:::: . ..: .:::.::. ..::::
CCDS10 VRVTAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 QASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWN
:... ..::::.::.:::. . . :.:. : : . ::: :: ::: :: ::: .
CCDS10 QTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 LKNGDTLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNP-VYVGNVAWA
...: : ::::::: ::::: .. ..: .: : . :. . ::::::::
CCDS10 VRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 HILALRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRL-DSRWSLPLTLM
:.:: : :. ..: . :: :. : .:..::...:. . :::: .: :: :.
CCDS10 HVLAARELE--QRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 YWIGFLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQ
... : ....:: :. : : .: .:....:..:: : :::: ..:.::.:::...
CCDS10 VFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRT
300 310 320 330 340 350
360 370
pF1KE4 KTVEWVGSLVDRHKETLKSKTQ
.:. ::
CCDS10 RTILWVQAATGSAQ
360
>>CCDS42205.1 SDR42E1 gene_id:93517|Hs108|chr16 (393 aa)
initn: 293 init1: 149 opt: 462 Z-score: 604.3 bits: 120.5 E(32554): 2.5e-27
Smith-Waterman score: 462; 34.8% identity (61.6% similar) in 310 aa overlap (58-355:54-349)
30 40 50 60 70 80
pF1KE4 LKEIRALDKAFRPELREEFSKLQNRTKLTVLEGDILDEPFLKRACQDVSVVIHTACIIDV
..::: ...: ::..:. :.. .
CCDS42 LGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLSDVEKAFQDADVT----CVFHI
30 40 50 60 70
90 100 110 120 130 140
pF1KE4 --FGVTHRES-----IMNVNVKGTQLLLEACVQASVPVFIYTSSIEVAGPNSYKEIIQNG
.:.. ::. : .:::.::. .:..: . :: ..:::...: . ..:.::
CCDS42 ASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIFGG---QVIRNG
80 90 100 110 120 130
150 160 170 180 190
pF1KE4 HEEEPLE--NTWPTPYPYSKKLAEKAVLAANGWNLKNGD-TLYTCALRPTYIYGEGGPFL
: : . : : .:..::. :: ::. : :: .: ::::::. ::: :
CCDS42 DESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTCALRPAGIYGPGEQRH
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE4 SASINEALNNNGILSSV--GKFSTVNPVYVGNVAWAHILALRALRDPKKAPSVRGQFYYI
: ... :... : : :. :.: :.. ::::: .::: :. . :: :.:
CCDS42 LPRIVSYIEK-GLFKFVYGDPRSLVEFVHVDNLVQAHILASEALR-ADKGHIASGQPYFI
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE4 SDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVVSFLLSPIYSYQPPFN
:: : .... . : . .: . : :::::.: ..:: :.: :.:. .:..:: ..
CCDS42 SDGRPVNNFEFFRP-LVEGLGYTFPST-RLPLTLVYCFAFLTEMVHFILGRLYNFQPFLT
260 270 280 290 300 310
320 330 340 350 360 370
pF1KE4 RHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLVDRHKETLKSKTQ
: : .. . :: .::...:.:: . :..:::
CCDS42 RTEVYKTGVTHYFSLEKAKKELGYK---AQPFDLQEAVEWFKAHGHGRSSGSRDSECFVW
320 330 340 350 360
CCDS42 DGLLVFLLIIAVLMWLPSSVILSL
370 380 390
>>CCDS45466.1 HSD3B7 gene_id:80270|Hs108|chr16 (196 aa)
initn: 370 init1: 312 opt: 396 Z-score: 522.5 bits: 104.4 E(32554): 8.8e-23
Smith-Waterman score: 396; 42.2% identity (72.3% similar) in 166 aa overlap (6-170:13-175)
10 20 30 40 50
pF1KE4 MGWSCLVTGAGGLLGQRIVRLLVE-EKELKEIRALDKAFRPELREEFSKLQNR
::::. :.::...::.:.. : .: :.:..:. . : : ::.. .
CCDS45 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWL-EELKT--GP
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 TKLTVLEGDILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACV
...:...::. . . : . :::::: ..:::: . ..: .:::.::. ..::::
CCDS45 VRVTAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 QASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWN
:... ..::::.::.:::. . . :.:. : : . ::: :: ::: :: :::
CCDS45 QTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 LKNGDTLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAH
CCDS45 AMLPGCTCWQPGSWSSGQP
180 190
>>CCDS14717.1 NSDHL gene_id:50814|Hs108|chrX (373 aa)
initn: 285 init1: 127 opt: 303 Z-score: 396.0 bits: 81.9 E(32554): 9.8e-16
Smith-Waterman score: 407; 29.2% identity (60.1% similar) in 353 aa overlap (5-354:40-364)
10 20 30
pF1KE4 MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRAL
: : :..:.:::..: :. : . :.
CCDS14 RDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMV-----EQLLARGYAV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE4 DKAFRPELREEFSKLQNRTKLTVLEGDILDEPFLKRACQDVSVVIHTACIIDVFGVTHRE
. .: .... :.. : : : ::. .. : : . :..:.: : . ...:
CCDS14 N-VF--DIQQGFDNPQVRFFL----GDLCSRQDLYPALKGVNTVFH--CASPPPSSNNKE
70 80 90 100 110
100 110 120 130 140 150
pF1KE4 SIMNVNVKGTQLLLEACVQASVPVFIYTSSIEVAGPNSYKEI-IQNGHEEEPLENTWPTP
.. :: ::. ..:.: .:.: .: ::: : .. . :.:: :. :
CCDS14 LFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDY
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE4 YPYSKKLAEKAVLAANGWNLKNGDTLYTCALRPTYIYGEGGPFLSASINEALNNNGILSS
: .: : :.:::.:: . :: . : :.:: :.: : : . :: :. .
CCDS14 YTETKILQERAVLGANDPE-KN---FLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFV
180 190 200 210 220
220 230 240 250 260 270
pF1KE4 VGKFST-VNPVYVGNVAWAHILALRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILS
.:. .. :. ..: ::. .:::: . : .. .. :. ..:..: : . :. ::.
CCDS14 IGNGKNLVDFTFVENVVHGHILAAEQL---SRDSTLGGKAFHITNDEPIPFWTFLSRILT
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE4 KEFGLRLDS-RWSLPLTLMYWIGFLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYK
:: .. .. .: . :....:: .. ...::. . :: :. :.:... .: .
CCDS14 ---GLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCE
290 300 310 320 330 340
340 350 360 370
pF1KE4 KAQRDLAYKPLYSWEEAKQKTVEWVGSLVDRHKETLKSKTQ
.:.. ..:.:: . ..: ..::.
CCDS14 RAKKAMGYQPLVTMDDAMERTVQSFRHLRRVK
350 360 370
372 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 02:06:30 2016 done: Sun Nov 6 02:06:30 2016
Total Scan time: 2.680 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]