Result of FASTA (ccds) for
pFN21AE4341
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4341, 354 aa
1>>>pF1KE4341 354 - 354 aa - 354 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4072+/-0.00092; mu= 15.7821+/- 0.055
mean_var=69.1166+/-13.837, 0's: 0 Z-trim(105.1): 12 B-trim: 0 in 0/51
Lambda= 0.154271
statistics sampled from 8233 (8239) to 8233 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.253), width: 16
Scan time: 2.300
The best scores are: opt bits E(32554)
CCDS5639.1 PON3 gene_id:5446|Hs108|chr7 ( 354) 2326 526.9 1e-149
CCDS5640.1 PON2 gene_id:5445|Hs108|chr7 ( 354) 1606 366.6 1.8e-101
CCDS5638.1 PON1 gene_id:5444|Hs108|chr7 ( 355) 1495 341.9 4.9e-94
CCDS47644.1 PON2 gene_id:5445|Hs108|chr7 ( 342) 1015 235.1 6.8e-62
>>CCDS5639.1 PON3 gene_id:5446|Hs108|chr7 (354 aa)
initn: 2326 init1: 2326 opt: 2326 Z-score: 2801.4 bits: 526.9 E(32554): 1e-149
Smith-Waterman score: 2326; 99.7% identity (100.0% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KE4 MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELENGSEDIDILPS
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
CCDS56 MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELESGSEDIDILPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGGFDKELFNPHGISIFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 GLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGGFDKELFNPHGISIFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 RDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 AKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 AKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPPG
250 260 270 280 290 300
310 320 330 340 350
pF1KE4 SEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 SEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL
310 320 330 340 350
>>CCDS5640.1 PON2 gene_id:5445|Hs108|chr7 (354 aa)
initn: 1606 init1: 1606 opt: 1606 Z-score: 1935.3 bits: 366.6 E(32554): 1.8e-101
Smith-Waterman score: 1606; 65.5% identity (89.5% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KE4 MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELENGSEDIDILPS
::.:::. :::..:.:.:: .::.:.:..:::::: :. .::::. .: :::::::::.
CCDS56 MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGGFDKELFNPHGISIFI
::::.: :::.::. .::::.:: :..:::.:..:::. :.:: ::: ::::::: ::
CCDS56 GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYAT
:.:.::::.:::::..:.::::::::: . ::..:::.::::: :::::...:: .::::
CCDS56 DNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 RDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVA
::::.. .:...: :.:.:. :..::: ::::::.:: :::::..: :.::.::::.
CCDS56 NDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 AKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPPG
:..::..::: : .::::::..: ::::::..::..::: .::::: .::. :.:..::.
CCDS56 AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPS
250 260 270 280 290 300
310 320 330 340 350
pF1KE4 SEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL
::::::::.::::: :.::::::::::::.:::::: ::.::::..:..:::::
CCDS56 SEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
310 320 330 340 350
>>CCDS5638.1 PON1 gene_id:5444|Hs108|chr7 (355 aa)
initn: 1486 init1: 1102 opt: 1495 Z-score: 1801.8 bits: 341.9 E(32554): 4.9e-94
Smith-Waterman score: 1495; 60.8% identity (85.6% similar) in 355 aa overlap (1-354:1-355)
10 20 30 40 50 60
pF1KE4 MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELENGSEDIDILPS
:.::.::.:::.::.: . ... :.:: :::.::: ::.:.. .:.::::..:::.
CCDS56 MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN
10 20 30 40 50 60
70 80 90 100 110
pF1KE4 GLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGG-FDKELFNPHGISIF
:::::::::::::. .: :. ::::.::::::..: . : :.:. :: ::::::: :
CCDS56 GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 IDKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYA
:.::..:: ::::: :::::.:::.:...::..::::.:.:: ..::::..:::.::.
CCDS56 TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 TRDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADV
: :::: . :. .:: : : :.::..::: ::.:::.:: ::::..: : ::::.:..
CCDS56 TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 AAKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPP
:..::..::: :: :: :: ....:::::..::: :::. .::::: ::.. :. :.::
CCDS56 LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 GSEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL
.::::::::.:.:.:.:. :::.::.::::..:::::.::.::::::::.:::::
CCDS56 ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
310 320 330 340 350
>>CCDS47644.1 PON2 gene_id:5445|Hs108|chr7 (342 aa)
initn: 1541 init1: 1013 opt: 1015 Z-score: 1224.7 bits: 235.1 E(32554): 6.8e-62
Smith-Waterman score: 1500; 62.7% identity (86.2% similar) in 354 aa overlap (1-354:1-342)
10 20 30 40 50 60
pF1KE4 MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELENGSEDIDILPS
::.:::. :::..:.:.:: .::.:.:..:::::: :. .::::. .: :::::::::.
CCDS47 MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGGFDKELFNPHGISIFI
::::.: :::.::. .::::.:: :..:::.:..:::. :.:: ::: ::::::: ::
CCDS47 GLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYAT
:.. .:.::::::::: . ::..:::.::::: :::::...:: .::::
CCDS47 DNE------------FKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYAT
130 140 150 160
190 200 210 220 230 240
pF1KE4 RDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVA
::::.. .:...: :.:.:. :..::: ::::::.:: :::::..: :.::.::::.
CCDS47 NDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADIL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE4 AKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPPG
:..::..::: : .::::::..: ::::::..::..::: .::::: .::. :.:..::.
CCDS47 AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPS
230 240 250 260 270 280
310 320 330 340 350
pF1KE4 SEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL
::::::::.::::: :.::::::::::::.:::::: ::.::::..:..:::::
CCDS47 SEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL
290 300 310 320 330 340
354 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:37:33 2016 done: Mon Nov 7 17:37:33 2016
Total Scan time: 2.300 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]