Result of FASTA (ccds) for
pFN21AE4339
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4339, 351 aa
1>>>pF1KE4339 351 - 351 aa - 351 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4535+/-0.000966; mu= 15.1858+/- 0.058
mean_var=64.3099+/-12.687, 0's: 0 Z-trim(104.1): 21 B-trim: 0 in 0/50
Lambda= 0.159932
statistics sampled from 7708 (7717) to 7708 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.615), E-opt: 0.2 (0.237), width: 16
Scan time: 2.610
The best scores are: opt bits E(32554)
CCDS9836.1 EIF2B2 gene_id:8892|Hs108|chr14 ( 351) 2262 530.9 6.3e-151
CCDS31924.1 EIF2B1 gene_id:1967|Hs108|chr12 ( 305) 319 82.5 5e-16
CCDS46244.1 EIF2B4 gene_id:8890|Hs108|chr2 ( 522) 295 77.1 3.7e-14
CCDS33164.1 EIF2B4 gene_id:8890|Hs108|chr2 ( 523) 295 77.1 3.7e-14
CCDS46245.1 EIF2B4 gene_id:8890|Hs108|chr2 ( 543) 295 77.1 3.9e-14
CCDS82432.1 EIF2B4 gene_id:8890|Hs108|chr2 ( 544) 295 77.1 3.9e-14
>>CCDS9836.1 EIF2B2 gene_id:8892|Hs108|chr14 (351 aa)
initn: 2262 init1: 2262 opt: 2262 Z-score: 2823.1 bits: 530.9 E(32554): 6.3e-151
Smith-Waterman score: 2262; 99.4% identity (100.0% similar) in 351 aa overlap (1-351:1-351)
10 20 30 40 50 60
pF1KE4 MPGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 MPGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 IRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRTDESDQQESLHKLLTSGGLNE
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
CCDS98 IRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 DFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 AARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 AARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 ANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEG
250 260 270 280 290 300
310 320 330 340 350
pF1KE4 DILEKVSVHCPVFDYVPPELITLFISNIGGNSPSYIYRLMSELYHPDDHVL
:::::::::::::::::::::::::::::::.:::::::::::::::::::
CCDS98 DILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL
310 320 330 340 350
>>CCDS31924.1 EIF2B1 gene_id:1967|Hs108|chr12 (305 aa)
initn: 235 init1: 166 opt: 319 Z-score: 401.2 bits: 82.5 E(32554): 5e-16
Smith-Waterman score: 327; 27.3% identity (60.7% similar) in 308 aa overlap (56-344:5-304)
30 40 50 60 70 80
pF1KE4 GGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQPSETTVGNMVRRV
::.: .. . .. .:. ... .: .
CCDS31 MDDKELIEYFKSQMKE----DPDMASAVAAIRTL
10 20 30
90 100 110 120
pF1KE4 LKIIREEYGR-LHG-RTDESDQQESLHKL-----LTSGG---------LNEDFSFHYAQL
:...... :. ..: :.. .. :.: . ..::: . ..: :..
CCDS31 LEFLKRDKGETIQGLRANLTSAIETLCGVDSSVAVSSGGELFLRFISLASLEYS-DYSKC
40 50 60 70 80
130 140 150 160 170 180
pF1KE4 QSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEA-ARKRKFH
.. .:: . .: .. . ..:: :... .:.: ..::.: :. : : :..:
CCDS31 KKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFS
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE4 VIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAV
: :.: : .:..:: : . .. .::. :::. .: ... ::.:.. .. ::..
CCDS31 VYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINK
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE4 TGTHTLALAAKHHSTPLIVCAPMFKLSPQFP-NEEDSFHKFVAPEEVLPFTE-GDILEKV
::. .:. :: .. :. : : ::. :: :..: :: ..: .. :. :..
CCDS31 IGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKE-
210 220 230 240 250 260
310 320 330 340 350
pF1KE4 SVHCPVFDYVPPELITLFISNIGGNSPSYIYRLMSELYHPDDHVL
: : ::. : ::::.....: .:: . . .::
CCDS31 -EH-PWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYL
270 280 290 300
>>CCDS46244.1 EIF2B4 gene_id:8890|Hs108|chr2 (522 aa)
initn: 196 init1: 155 opt: 295 Z-score: 367.6 bits: 77.1 E(32554): 3.7e-14
Smith-Waterman score: 295; 28.4% identity (62.9% similar) in 232 aa overlap (109-329:279-504)
80 90 100 110 120 130
pF1KE4 GNMVRRVLKIIREEYGRLHGRTDESDQQESLHKLLTSGGLNEDFSFHYAQLQSNIIEAIN
:.: .:: : .. ..:.. : . ..
CCDS46 RDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQ
250 260 270 280 290 300
140 150 160 170 180 190
pF1KE4 ELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEA-ARKRKFHVIVAECAPF
: .: . . :. : ..: ...::.. : : : .:.:: .. :.:.:.:.. :.
CCDS46 EKIVL---AAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPW
310 320 330 340 350 360
200 210 220 230 240 250
pF1KE4 CQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALA
.:.. .: .::. .. . : :. .:.::..:....::::.. . .:: :::.
CCDS46 LEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALV
370 380 390 400 410 420
260 270 280 290 300 310
pF1KE4 AKHHSTPLIVCAPMFKLSPQFPNEEDSF--HKFVAPEEVLPFTEGD--ILEKVSVHCP--
:. :..:..:: .:. . . :.: ... :.. : .:. : . . :
CCDS46 ARAHNVPVLVCCETYKFCERV--QTDAFVSNELDDPDD-LQCKRGEHVALANWQNHASLR
430 440 450 460 470 480
320 330 340 350
pF1KE4 ----VFDYVPPELITLFISNIGGNSPSYIYRLMSELYHPDDHVL
:.: .::::. : :...:
CCDS46 LLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
490 500 510 520
>>CCDS33164.1 EIF2B4 gene_id:8890|Hs108|chr2 (523 aa)
initn: 196 init1: 155 opt: 295 Z-score: 367.6 bits: 77.1 E(32554): 3.7e-14
Smith-Waterman score: 295; 28.4% identity (62.9% similar) in 232 aa overlap (109-329:280-505)
80 90 100 110 120 130
pF1KE4 GNMVRRVLKIIREEYGRLHGRTDESDQQESLHKLLTSGGLNEDFSFHYAQLQSNIIEAIN
:.: .:: : .. ..:.. : . ..
CCDS33 RDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQ
250 260 270 280 290 300
140 150 160 170 180 190
pF1KE4 ELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEA-ARKRKFHVIVAECAPF
: .: . . :. : ..: ...::.. : : : .:.:: .. :.:.:.:.. :.
CCDS33 EKIVL---AAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPW
310 320 330 340 350 360
200 210 220 230 240 250
pF1KE4 CQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALA
.:.. .: .::. .. . : :. .:.::..:....::::.. . .:: :::.
CCDS33 LEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALV
370 380 390 400 410 420
260 270 280 290 300 310
pF1KE4 AKHHSTPLIVCAPMFKLSPQFPNEEDSF--HKFVAPEEVLPFTEGD--ILEKVSVHCP--
:. :..:..:: .:. . . :.: ... :.. : .:. : . . :
CCDS33 ARAHNVPVLVCCETYKFCERV--QTDAFVSNELDDPDD-LQCKRGEHVALANWQNHASLR
430 440 450 460 470 480
320 330 340 350
pF1KE4 ----VFDYVPPELITLFISNIGGNSPSYIYRLMSELYHPDDHVL
:.: .::::. : :...:
CCDS33 LLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
490 500 510 520
>>CCDS46245.1 EIF2B4 gene_id:8890|Hs108|chr2 (543 aa)
initn: 196 init1: 155 opt: 295 Z-score: 367.3 bits: 77.1 E(32554): 3.9e-14
Smith-Waterman score: 295; 28.4% identity (62.9% similar) in 232 aa overlap (109-329:300-525)
80 90 100 110 120 130
pF1KE4 GNMVRRVLKIIREEYGRLHGRTDESDQQESLHKLLTSGGLNEDFSFHYAQLQSNIIEAIN
:.: .:: : .. ..:.. : . ..
CCDS46 RDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQ
270 280 290 300 310 320
140 150 160 170 180 190
pF1KE4 ELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEA-ARKRKFHVIVAECAPF
: .: . . :. : ..: ...::.. : : : .:.:: .. :.:.:.:.. :.
CCDS46 EKIVL---AAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPW
330 340 350 360 370 380
200 210 220 230 240 250
pF1KE4 CQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALA
.:.. .: .::. .. . : :. .:.::..:....::::.. . .:: :::.
CCDS46 LEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALV
390 400 410 420 430 440
260 270 280 290 300 310
pF1KE4 AKHHSTPLIVCAPMFKLSPQFPNEEDSF--HKFVAPEEVLPFTEGD--ILEKVSVHCP--
:. :..:..:: .:. . . :.: ... :.. : .:. : . . :
CCDS46 ARAHNVPVLVCCETYKFCERV--QTDAFVSNELDDPDD-LQCKRGEHVALANWQNHASLR
450 460 470 480 490 500
320 330 340 350
pF1KE4 ----VFDYVPPELITLFISNIGGNSPSYIYRLMSELYHPDDHVL
:.: .::::. : :...:
CCDS46 LLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
510 520 530 540
>>CCDS82432.1 EIF2B4 gene_id:8890|Hs108|chr2 (544 aa)
initn: 196 init1: 155 opt: 295 Z-score: 367.3 bits: 77.1 E(32554): 3.9e-14
Smith-Waterman score: 295; 28.4% identity (62.9% similar) in 232 aa overlap (109-329:301-526)
80 90 100 110 120 130
pF1KE4 GNMVRRVLKIIREEYGRLHGRTDESDQQESLHKLLTSGGLNEDFSFHYAQLQSNIIEAIN
:.: .:: : .. ..:.. : . ..
CCDS82 RDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQ
280 290 300 310 320 330
140 150 160 170 180 190
pF1KE4 ELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEA-ARKRKFHVIVAECAPF
: .: . . :. : ..: ...::.. : : : .:.:: .. :.:.:.:.. :.
CCDS82 EKIVL---AAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPW
340 350 360 370 380
200 210 220 230 240 250
pF1KE4 CQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALA
.:.. .: .::. .. . : :. .:.::..:....::::.. . .:: :::.
CCDS82 LEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALV
390 400 410 420 430 440
260 270 280 290 300 310
pF1KE4 AKHHSTPLIVCAPMFKLSPQFPNEEDSF--HKFVAPEEVLPFTEGD--ILEKVSVHCP--
:. :..:..:: .:. . . :.: ... :.. : .:. : . . :
CCDS82 ARAHNVPVLVCCETYKFCERV--QTDAFVSNELDDPDD-LQCKRGEHVALANWQNHASLR
450 460 470 480 490 500
320 330 340 350
pF1KE4 ----VFDYVPPELITLFISNIGGNSPSYIYRLMSELYHPDDHVL
:.: .::::. : :...:
CCDS82 LLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
510 520 530 540
351 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 02:12:00 2016 done: Sun Nov 6 02:12:01 2016
Total Scan time: 2.610 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]