Result of FASTA (omim) for
pFN21AE4336
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4336, 347 aa
1>>>pF1KE4336 347 - 347 aa - 347 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2466+/-0.000372; mu= 16.3641+/- 0.023
mean_var=63.2223+/-13.203, 0's: 0 Z-trim(113.7): 18 B-trim: 184 in 1/50
Lambda= 0.161302
statistics sampled from 23168 (23182) to 23168 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.272), width: 16
Scan time: 7.900
The best scores are: opt bits E(85289)
XP_011536306 (OMIM: 124050,181500) PREDICTED: D-am ( 347) 2415 570.6 1.7e-162
NP_001908 (OMIM: 124050,181500) D-amino-acid oxida ( 347) 2415 570.6 1.7e-162
XP_011536307 (OMIM: 124050,181500) PREDICTED: D-am ( 347) 2415 570.6 1.7e-162
XP_005268749 (OMIM: 124050,181500) PREDICTED: D-am ( 325) 1366 326.5 5e-89
NP_003640 (OMIM: 124450) D-aspartate oxidase isofo ( 369) 852 206.9 5.6e-53
NP_004023 (OMIM: 124450) D-aspartate oxidase isofo ( 310) 469 117.8 3.3e-26
>>XP_011536306 (OMIM: 124050,181500) PREDICTED: D-amino- (347 aa)
initn: 2415 init1: 2415 opt: 2415 Z-score: 3038.2 bits: 570.6 E(85289): 1.7e-162
Smith-Waterman score: 2415; 100.0% identity (100.0% similar) in 347 aa overlap (1-347:1-347)
10 20 30 40 50 60
pF1KE4 MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
250 260 270 280 290 300
310 320 330 340
pF1KE4 SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
310 320 330 340
>>NP_001908 (OMIM: 124050,181500) D-amino-acid oxidase [ (347 aa)
initn: 2415 init1: 2415 opt: 2415 Z-score: 3038.2 bits: 570.6 E(85289): 1.7e-162
Smith-Waterman score: 2415; 100.0% identity (100.0% similar) in 347 aa overlap (1-347:1-347)
10 20 30 40 50 60
pF1KE4 MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
250 260 270 280 290 300
310 320 330 340
pF1KE4 SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
310 320 330 340
>>XP_011536307 (OMIM: 124050,181500) PREDICTED: D-amino- (347 aa)
initn: 2415 init1: 2415 opt: 2415 Z-score: 3038.2 bits: 570.6 E(85289): 1.7e-162
Smith-Waterman score: 2415; 100.0% identity (100.0% similar) in 347 aa overlap (1-347:1-347)
10 20 30 40 50 60
pF1KE4 MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
250 260 270 280 290 300
310 320 330 340
pF1KE4 SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
310 320 330 340
>>XP_005268749 (OMIM: 124050,181500) PREDICTED: D-amino- (325 aa)
initn: 2242 init1: 1366 opt: 1366 Z-score: 1719.4 bits: 326.5 E(85289): 5e-89
Smith-Waterman score: 2202; 93.7% identity (93.7% similar) in 347 aa overlap (1-347:1-325)
10 20 30 40 50 60
pF1KE4 MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
::::::::: :::::::::::::::::::::::::::::
XP_005 ELDMFPDYG----------------------LTERGVKFFQRKVESFEEVAREGADVIVN
130 140 150
190 200 210 220 230 240
pF1KE4 CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE4 IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
220 230 240 250 260 270
310 320 330 340
pF1KE4 SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
280 290 300 310 320
>>NP_003640 (OMIM: 124450) D-aspartate oxidase isoform a (369 aa)
initn: 716 init1: 334 opt: 852 Z-score: 1072.1 bits: 206.9 E(85289): 5.6e-53
Smith-Waterman score: 852; 39.6% identity (66.4% similar) in 351 aa overlap (2-347:33-369)
10 20 30
pF1KE4 MRVVVIGAGVIGLSTALCIHERYHSVLQP-L
:..:.::::.:::::.:: : : :
NP_003 PARHWETRFGARDFGGFQDCFFRDRLMDTARIAVVGAGVVGLSTAVCI-----SKLVPRC
10 20 30 40 50
40 50 60 70 80
pF1KE4 DIKVYADRFTPLTTTDVAAGLWQPYLSDPNNP--QEADWSQQTFDYLLSHVHSPNAENLG
.. . .:.::: ::.:::::. :. . :..: . .: ..::..:.. ..: .: . :
NP_003 SVTIISDKFTPDTTSDVAAGMLIPH-TYPDTPIHTQKQWFRETFNHLFAIANSAEAGDAG
60 70 80 90 100 110
90 100 110 120 130 140
pF1KE4 LFLISGYNLFHEAIPD--PSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQ
. :.::...:. . . : : :.::::::.: :: ::.: .: :.: : ::
NP_003 VHLVSGWQIFQSTPTEEVPFWADVVLGFRKMTEAELKKFPQYVFGQAFTTLKCECPAYLP
120 130 140 150 160 170
150 160 170 180 190 200
pF1KE4 WLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVD
:: .:. : . :..:.. :. . . :..:::.:. . : : . : :::...:.
NP_003 WLEKRIKGSGGWTLTRRIEDLWEL-HPSFDIVVNCSGLGSRQLAGDSKIFPVRGQVLQVQ
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE4 APWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRL
:::..::: : . :: :::. ::::: : :.:. . .. : :: :
NP_003 APWVEHFI------RDGSGLTYIYPGTSHVTLGGTRQKGDWNLSPDAENSREILSRCCAL
240 250 260 270 280
270 280 290 300 310 320
pF1KE4 EPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEA
::.:..: : :..:.:: :: .::. : : . :.:.::::. :...::: ::::
NP_003 EPSLHGACNIREKVGLRPYRPGVRLQTELLARDGQRLPVVHHYGHGSGGISVHWGTALEA
290 300 310 320 330 340
330 340
pF1KE4 AKLFGRILEEKKLSRMPPSHL
:.: .. .. . . .: :.:
NP_003 ARLVSECVHALR-TPIPKSNL
350 360
>>NP_004023 (OMIM: 124450) D-aspartate oxidase isoform b (310 aa)
initn: 600 init1: 334 opt: 469 Z-score: 591.6 bits: 117.8 E(85289): 3.3e-26
Smith-Waterman score: 588; 33.5% identity (57.0% similar) in 349 aa overlap (2-347:33-310)
10 20 30
pF1KE4 MRVVVIGAGVIGLSTALCIHERYHSVLQP-L
:..:.::::.:::::.:: : : :
NP_004 PARHWETRFGARDFGGFQDCFFRDRLMDTARIAVVGAGVVGLSTAVCI-----SKLVPRC
10 20 30 40 50
40 50 60 70 80
pF1KE4 DIKVYADRFTPLTTTDVAAGLWQPYLSDPNNP--QEADWSQQTFDYLLSHVHSPNAENLG
.. . .:.::: ::.:::::. :. . :..: . .: ..::..:.. ..: .: . :
NP_004 SVTIISDKFTPDTTSDVAAGMLIPH-TYPDTPIHTQKQWFRETFNHLFAIANSAEAGDAG
60 70 80 90 100 110
90 100 110 120 130 140
pF1KE4 LFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWL
. :.:: . : . :: :
NP_004 VHLVSG----------------IKG---------------SGGWTLT-------------
120 130
150 160 170 180 190 200
pF1KE4 TERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAP
:..:.. :. . . :..:::.:. . : : . : :::...:.::
NP_004 -------------RRIEDLWEL-HPSFDIVVNCSGLGSRQLAGDSKIFPVRGQVLQVQAP
140 150 160 170
210 220 230 240 250 260
pF1KE4 WMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEP
:..::: : . :: :::. ::::: : :.:. . .. : :: :::
NP_004 WVEHFI------RDGSGLTYIYPGTSHVTLGGTRQKGDWNLSPDAENSREILSRCCALEP
180 190 200 210 220 230
270 280 290 300 310 320
pF1KE4 TLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEAAK
.:..: : :..:.:: :: .::. : : . :.:.::::. :...::: :::::.
NP_004 SLHGACNIREKVGLRPYRPGVRLQTELLARDGQRLPVVHHYGHGSGGISVHWGTALEAAR
240 250 260 270 280 290
330 340
pF1KE4 LFGRILEEKKLSRMPPSHL
: .. .. . . .: :.:
NP_004 LVSECVHALR-TPIPKSNL
300 310
347 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 02:13:15 2016 done: Sun Nov 6 02:13:16 2016
Total Scan time: 7.900 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]