Result of FASTA (omim) for
pFN21AE4331
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4331, 338 aa
1>>>pF1KE4331 338 - 338 aa - 338 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2837+/-0.000393; mu= 16.6173+/- 0.024
mean_var=67.6396+/-13.899, 0's: 0 Z-trim(112.1): 27 B-trim: 51 in 1/49
Lambda= 0.155946
statistics sampled from 20942 (20962) to 20942 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.246), width: 16
Scan time: 7.940
The best scores are: opt bits E(85289)
NP_005909 (OMIM: 154100) malate dehydrogenase, mit ( 338) 2166 496.3 3.8e-140
NP_001269333 (OMIM: 154100) malate dehydrogenase, ( 231) 1482 342.3 5.9e-94
NP_001269332 (OMIM: 154100) malate dehydrogenase, ( 296) 980 229.4 7.3e-60
NP_002292 (OMIM: 150150) L-lactate dehydrogenase C ( 332) 217 57.8 3.8e-08
NP_059144 (OMIM: 150150) L-lactate dehydrogenase C ( 332) 217 57.8 3.8e-08
NP_001167568 (OMIM: 150100,614128) L-lactate dehyd ( 334) 213 56.9 7.1e-08
NP_002291 (OMIM: 150100,614128) L-lactate dehydrog ( 334) 213 56.9 7.1e-08
NP_001302466 (OMIM: 150100,614128) L-lactate dehyd ( 341) 213 56.9 7.2e-08
XP_006719137 (OMIM: 150100,614128) PREDICTED: L-la ( 353) 193 52.4 1.7e-06
NP_005557 (OMIM: 150000,612933) L-lactate dehydrog ( 332) 185 50.6 5.5e-06
NP_001158886 (OMIM: 150000,612933) L-lactate dehyd ( 361) 185 50.6 5.9e-06
NP_005908 (OMIM: 154200) malate dehydrogenase, cyt ( 334) 182 49.9 8.9e-06
NP_001186040 (OMIM: 154200) malate dehydrogenase, ( 352) 182 50.0 9.3e-06
NP_001303303 (OMIM: 154200) malate dehydrogenase, ( 353) 182 50.0 9.3e-06
>>NP_005909 (OMIM: 154100) malate dehydrogenase, mitocho (338 aa)
initn: 2166 init1: 2166 opt: 2166 Z-score: 2637.0 bits: 496.3 E(85289): 3.8e-140
Smith-Waterman score: 2166; 99.7% identity (100.0% similar) in 338 aa overlap (1-338:1-338)
10 20 30 40 50 60
pF1KE4 MLSALARPVSAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MLSALARPASAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 VATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 KAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIE
250 260 270 280 290 300
310 320 330
pF1KE4 KNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
::::::::::::::::::::::::::::::::::::::
NP_005 KNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
310 320 330
>>NP_001269333 (OMIM: 154100) malate dehydrogenase, mito (231 aa)
initn: 1482 init1: 1482 opt: 1482 Z-score: 1807.7 bits: 342.3 E(85289): 5.9e-94
Smith-Waterman score: 1482; 100.0% identity (100.0% similar) in 231 aa overlap (108-338:1-231)
80 90 100 110 120 130
pF1KE4 KGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMI
::::::::::::::::::::::::::::::
NP_001 MTRDDLFNTNATIVATLTAACAQHCPEAMI
10 20 30
140 150 160 170 180 190
pF1KE4 CVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVI
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE4 GGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGAR
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE4 FVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMIS
160 170 180 190 200 210
320 330
pF1KE4 DAIPELKASIKKGEDFVKTLK
:::::::::::::::::::::
NP_001 DAIPELKASIKKGEDFVKTLK
220 230
>>NP_001269332 (OMIM: 154100) malate dehydrogenase, mito (296 aa)
initn: 1890 init1: 977 opt: 980 Z-score: 1195.8 bits: 229.4 E(85289): 7.3e-60
Smith-Waterman score: 1810; 87.3% identity (87.6% similar) in 338 aa overlap (1-338:1-296)
10 20 30 40 50 60
pF1KE4 MLSALARPVSAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLSALARPASAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 VATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTF
:::::::::::::::::::::::
NP_001 VATLTAACAQHCPEAMICVIANP-------------------------------------
130 140
190 200 210 220 230 240
pF1KE4 VAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -----GLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKA
150 160 170 180 190
250 260 270 280 290 300
pF1KE4 KAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIE
200 210 220 230 240 250
310 320 330
pF1KE4 KNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
::::::::::::::::::::::::::::::::::::::
NP_001 KNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
260 270 280 290
>>NP_002292 (OMIM: 150150) L-lactate dehydrogenase C cha (332 aa)
initn: 92 init1: 92 opt: 217 Z-score: 267.3 bits: 57.8 E(85289): 3.8e-08
Smith-Waterman score: 217; 23.4% identity (55.4% similar) in 316 aa overlap (26-323:22-323)
10 20 30 40 50
pF1KE4 MLSALARPVSAALRRSFSTSAQNNAKVAVLGASGGIGQP--LSLLLKNSPLVSRLTLYDI
:....: .:..:. .:.:::. :...:.: :.
NP_002 MSTVKEQLIEKLIEDDENSQCKITIVG-TGAVGMACAISILLKD--LADELALVDV
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 A--HTPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT
: . : ::.: ... . .. . . .:.. ::. .. : :: : .
NP_002 ALDKLKGEMMDLQHGSLFFSTSKITSGKDY-SVSANSRIVIVTAGARQQEGETRLALVQR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 NATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVR
:..:. .. : ... :. : :..:::. .: :.: :. : . .:: .:
NP_002 NVAIMKSIIPAIVHYSPDCKILVVSNPVDI---LTYIVWKISGLPVTRVIGSGCNLDSAR
120 130 140 150 160
180 190 200 210 220
pF1KE4 ANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCT----------PKV--DFPQDQLT
...: :. :. . .:: : : . .:: : . ::. : ...
NP_002 FRYLIGEKLGVHPTSCHGWIIGEH-GDSSVPLWSGVNVAGVALKTLDPKLGTDSDKEHWK
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE4 ALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQE--
. .. ... :..: : : .. ... . .: :.. . . : ..::.
NP_002 NIHKQVIQSAYEIIKLK---GYTSWAIGLSVMDLVGSILKNLRRVHPV--STMVKGLYGI
230 240 250 260 270 280
290 300 310 320 330
pF1KE4 TECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
: ..: : .::..:. . :. ..: :: ... . :
NP_002 KEELFLSIPCVLGRNGVSDVVKIN-LNSEEEALFKKSAETLWNIQKDLIF
290 300 310 320 330
>>NP_059144 (OMIM: 150150) L-lactate dehydrogenase C cha (332 aa)
initn: 92 init1: 92 opt: 217 Z-score: 267.3 bits: 57.8 E(85289): 3.8e-08
Smith-Waterman score: 217; 23.4% identity (55.4% similar) in 316 aa overlap (26-323:22-323)
10 20 30 40 50
pF1KE4 MLSALARPVSAALRRSFSTSAQNNAKVAVLGASGGIGQP--LSLLLKNSPLVSRLTLYDI
:....: .:..:. .:.:::. :...:.: :.
NP_059 MSTVKEQLIEKLIEDDENSQCKITIVG-TGAVGMACAISILLKD--LADELALVDV
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 A--HTPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT
: . : ::.: ... . .. . . .:.. ::. .. : :: : .
NP_059 ALDKLKGEMMDLQHGSLFFSTSKITSGKDY-SVSANSRIVIVTAGARQQEGETRLALVQR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 NATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVR
:..:. .. : ... :. : :..:::. .: :.: :. : . .:: .:
NP_059 NVAIMKSIIPAIVHYSPDCKILVVSNPVDI---LTYIVWKISGLPVTRVIGSGCNLDSAR
120 130 140 150 160
180 190 200 210 220
pF1KE4 ANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCT----------PKV--DFPQDQLT
...: :. :. . .:: : : . .:: : . ::. : ...
NP_059 FRYLIGEKLGVHPTSCHGWIIGEH-GDSSVPLWSGVNVAGVALKTLDPKLGTDSDKEHWK
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE4 ALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQE--
. .. ... :..: : : .. ... . .: :.. . . : ..::.
NP_059 NIHKQVIQSAYEIIKLK---GYTSWAIGLSVMDLVGSILKNLRRVHPV--STMVKGLYGI
230 240 250 260 270 280
290 300 310 320 330
pF1KE4 TECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
: ..: : .::..:. . :. ..: :: ... . :
NP_059 KEELFLSIPCVLGRNGVSDVVKIN-LNSEEEALFKKSAETLWNIQKDLIF
290 300 310 320 330
>>NP_001167568 (OMIM: 150100,614128) L-lactate dehydroge (334 aa)
initn: 103 init1: 103 opt: 213 Z-score: 262.4 bits: 56.9 E(85289): 7.1e-08
Smith-Waterman score: 213; 21.8% identity (55.0% similar) in 331 aa overlap (24-338:21-332)
10 20 30 40 50 60
pF1KE4 MLSALARPVSAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
: :..:.:. : .:. .. . .. :...:.: :. .
NP_001 MATLKEKLIAPVAEEEATVPNNKITVVGV-GQVGMACAISILGKSLADELALVDVLE
10 20 30 40 50
70 80 90 100 110
pF1KE4 TP--GVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNA
: ::.: . .. .. . . .::. ::: .. : .: .: . :.
NP_001 DKLKGEMMDLQHGSLFLQTPKIVADKDY-SVTANSKIVVVTAGVRQQEGESRLNLVQRNV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 TIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRAN
.. . ... :. .: :..:::. .: .: :. . : . .:: .:
NP_001 NVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT---WKLSGLPKHRVIGSGCNLDSARFR
120 130 140 150 160 170
180 190 200 210 220
pF1KE4 TFVAELKGLDPARVNVPVIGGHAGKTI-------IPLIS--QCTPKV--DFPQDQLTALT
..:: :. :. . ..: :. ... . .: . .:.. : ... .
NP_001 YLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVH
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 GRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQ---ETE
. :.. ::.: : : .. ... . : .. :.. .. . : ..::.. :.:
NP_001 KMVVESAYEVIKLK---GYTNWAIGLSVADLIESMLKNLSRIHPV--STMVKGMYGIENE
240 250 260 270 280
290 300 310 320 330
pF1KE4 CTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
...: : .:. .:. .: ...:. .: . .:: : :. : ::
NP_001 -VFLSLPCILNARGL--------TSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL
290 300 310 320 330
>>NP_002291 (OMIM: 150100,614128) L-lactate dehydrogenas (334 aa)
initn: 103 init1: 103 opt: 213 Z-score: 262.4 bits: 56.9 E(85289): 7.1e-08
Smith-Waterman score: 213; 21.8% identity (55.0% similar) in 331 aa overlap (24-338:21-332)
10 20 30 40 50 60
pF1KE4 MLSALARPVSAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
: :..:.:. : .:. .. . .. :...:.: :. .
NP_002 MATLKEKLIAPVAEEEATVPNNKITVVGV-GQVGMACAISILGKSLADELALVDVLE
10 20 30 40 50
70 80 90 100 110
pF1KE4 TP--GVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNA
: ::.: . .. .. . . .::. ::: .. : .: .: . :.
NP_002 DKLKGEMMDLQHGSLFLQTPKIVADKDY-SVTANSKIVVVTAGVRQQEGESRLNLVQRNV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 TIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRAN
.. . ... :. .: :..:::. .: .: :. . : . .:: .:
NP_002 NVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT---WKLSGLPKHRVIGSGCNLDSARFR
120 130 140 150 160 170
180 190 200 210 220
pF1KE4 TFVAELKGLDPARVNVPVIGGHAGKTI-------IPLIS--QCTPKV--DFPQDQLTALT
..:: :. :. . ..: :. ... . .: . .:.. : ... .
NP_002 YLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVH
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 GRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQ---ETE
. :.. ::.: : : .. ... . : .. :.. .. . : ..::.. :.:
NP_002 KMVVESAYEVIKLK---GYTNWAIGLSVADLIESMLKNLSRIHPV--STMVKGMYGIENE
240 250 260 270 280
290 300 310 320 330
pF1KE4 CTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
...: : .:. .:. .: ...:. .: . .:: : :. : ::
NP_002 -VFLSLPCILNARGL--------TSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL
290 300 310 320 330
>>NP_001302466 (OMIM: 150100,614128) L-lactate dehydroge (341 aa)
initn: 103 init1: 103 opt: 213 Z-score: 262.3 bits: 56.9 E(85289): 7.2e-08
Smith-Waterman score: 213; 21.8% identity (55.0% similar) in 331 aa overlap (24-338:21-332)
10 20 30 40 50 60
pF1KE4 MLSALARPVSAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
: :..:.:. : .:. .. . .. :...:.: :. .
NP_001 MATLKEKLIAPVAEEEATVPNNKITVVGV-GQVGMACAISILGKSLADELALVDVLE
10 20 30 40 50
70 80 90 100 110
pF1KE4 TP--GVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNA
: ::.: . .. .. . . .::. ::: .. : .: .: . :.
NP_001 DKLKGEMMDLQHGSLFLQTPKIVADKDY-SVTANSKIVVVTAGVRQQEGESRLNLVQRNV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 TIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRAN
.. . ... :. .: :..:::. .: .: :. . : . .:: .:
NP_001 NVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT---WKLSGLPKHRVIGSGCNLDSARFR
120 130 140 150 160 170
180 190 200 210 220
pF1KE4 TFVAELKGLDPARVNVPVIGGHAGKTI-------IPLIS--QCTPKV--DFPQDQLTALT
..:: :. :. . ..: :. ... . .: . .:.. : ... .
NP_001 YLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVH
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 GRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQ---ETE
. :.. ::.: : : .. ... . : .. :.. .. . : ..::.. :.:
NP_001 KMVVESAYEVIKLK---GYTNWAIGLSVADLIESMLKNLSRIHPV--STMVKGMYGIENE
240 250 260 270 280
290 300 310 320 330
pF1KE4 CTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
...: : .:. .:. .: ...:. .: . .:: : :. : ::
NP_001 -VFLSLPCILNARGL--------TSVINQKLKDDEVAQLKKSADTLWDIQKDLKDLXLVS
290 300 310 320 330
NP_001 SRL
340
>>XP_006719137 (OMIM: 150100,614128) PREDICTED: L-lactat (353 aa)
initn: 103 init1: 103 opt: 193 Z-score: 237.7 bits: 52.4 E(85289): 1.7e-06
Smith-Waterman score: 193; 20.3% identity (54.6% similar) in 291 aa overlap (24-301:21-303)
10 20 30 40 50 60
pF1KE4 MLSALARPVSAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
: :..:.:. : .:. .. . .. :...:.: :. .
XP_006 MATLKEKLIAPVAEEEATVPNNKITVVGV-GQVGMACAISILGKSLADELALVDVLE
10 20 30 40 50
70 80 90 100 110
pF1KE4 TP--GVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNA
: ::.: . .. .. . . .::. ::: .. : .: .: . :.
XP_006 DKLKGEMMDLQHGSLFLQTPKIVADKDY-SVTANSKIVVVTAGVRQQEGESRLNLVQRNV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 TIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRAN
.. . ... :. .: :..:::. .: .: :. . : . .:: .:
XP_006 NVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVT---WKLSGLPKHRVIGSGCNLDSARFR
120 130 140 150 160 170
180 190 200 210 220
pF1KE4 TFVAELKGLDPARVNVPVIGGHAGKTI-------IPLIS--QCTPKV--DFPQDQLTALT
..:: :. :. . ..: :. ... . .: . .:.. : ... .
XP_006 YLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVH
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 GRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTY
. :.. ::.: : : .. ... . : .. :.. .. . : :.. :.:..
XP_006 KMVVESAYEVIKLK---GYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKVRQTTTKCNM
240 250 260 270 280
290 300 310 320 330
pF1KE4 FSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
.: .. : ...
XP_006 ISRIVFYKKIHLKRLRPDKIIVQGYFCLSKFYVNYSHFPTEVLDSKGRKLRESKTFNRLL
290 300 310 320 330 340
>>NP_005557 (OMIM: 150000,612933) L-lactate dehydrogenas (332 aa)
initn: 48 init1: 48 opt: 185 Z-score: 228.4 bits: 50.6 E(85289): 5.5e-06
Smith-Waterman score: 198; 22.7% identity (54.2% similar) in 321 aa overlap (20-319:18-320)
10 20 30 40 50 60
pF1KE4 MLSALARPVSAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
. ::. :. .:: : .. .:.:.:. :...:.: :. .
NP_005 MATLKDQLIYNLLKEEQTPQNKITVVGVGAVG-MACAISILMKD--LADELALVDVIE
10 20 30 40 50
70 80 90 100 110
pF1KE4 TP--GVAADLSH----IETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLF
: ::.: ..: :.: . . . .:.: ::. .. : .: .:
NP_005 DKLKGEMMDLQHGSLFLRTPKIVSG-----KDYNVTANSKLVIITAGARQQEGESRLNLV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 NTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGV-TTLD
. :..: . ... :. . ...:::. .: ..: : . :...: .::
NP_005 QRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDI---LTYVAWKISG-FPKNRVIGSGCNLD
120 130 140 150 160
180 190 200 210 220
pF1KE4 IVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPL--------ISQCTPKVDFPQD----
.: ...: :. : . :.: : : . .:. .: : . :. :
NP_005 SARFRYLMGERLGVHPLSCHGWVLGEH-GDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKE
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE4 QLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQ
: . .. :.. ::.: : : .. ... . : .. :.. . . : ...:.
NP_005 QWKEVHKQVVESAYEVIKLK---GYTSWAIGLSVADLAESIMKNLRRVHPV--STMIKGL
230 240 250 260 270 280
290 300 310 320 330
pF1KE4 E--TECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
. ...:.: .::..:: . . .: : .. ..:
NP_005 YGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF
290 300 310 320 330
338 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 06:27:02 2016 done: Thu Nov 3 06:27:03 2016
Total Scan time: 7.940 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]