FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4331, 338 aa
  1>>>pF1KE4331 338 - 338 aa - 338 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6466+/-0.000871; mu= 14.0600+/- 0.052
 mean_var=63.0350+/-12.573, 0's: 0 Z-trim(105.3): 21  B-trim: 4 in 1/49
 Lambda= 0.161541
 statistics sampled from 8352 (8369) to 8352 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.257), width:  16
 Scan time:  2.640

The best scores are:                                      opt bits E(32554)
CCDS5581.1 MDH2 gene_id:4191|Hs108|chr7            ( 338) 2166 513.5  1e-145
CCDS75622.1 MDH2 gene_id:4191|Hs108|chr7           ( 231) 1482 354.0   7e-98
CCDS64691.1 MDH2 gene_id:4191|Hs108|chr7           ( 296)  980 237.0 1.4e-62


>>CCDS5581.1 MDH2 gene_id:4191|Hs108|chr7                 (338 aa)
 initn: 2166 init1: 2166 opt: 2166  Z-score: 2729.6  bits: 513.5 E(32554): 1e-145
Smith-Waterman score: 2166; 99.7% identity (100.0% similar) in 338 aa overlap (1-338:1-338)

               10        20        30        40        50        60
pF1KE4 MLSALARPVSAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
       ::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MLSALARPASAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 VATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 VATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 VAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 VAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 KAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIE
              250       260       270       280       290       300

              310       320       330        
pF1KE4 KNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
       ::::::::::::::::::::::::::::::::::::::
CCDS55 KNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
              310       320       330        

>>CCDS75622.1 MDH2 gene_id:4191|Hs108|chr7                (231 aa)
 initn: 1482 init1: 1482 opt: 1482  Z-score: 1870.8  bits: 354.0 E(32554): 7e-98
Smith-Waterman score: 1482; 100.0% identity (100.0% similar) in 231 aa overlap (108-338:1-231)

        80        90       100       110       120       130       
pF1KE4 KGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMI
                                     ::::::::::::::::::::::::::::::
CCDS75                               MTRDDLFNTNATIVATLTAACAQHCPEAMI
                                             10        20        30

       140       150       160       170       180       190       
pF1KE4 CVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 CVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVI
               40        50        60        70        80        90

       200       210       220       230       240       250       
pF1KE4 GGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 GGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGAR
              100       110       120       130       140       150

       260       270       280       290       300       310       
pF1KE4 FVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 FVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMIS
              160       170       180       190       200       210

       320       330        
pF1KE4 DAIPELKASIKKGEDFVKTLK
       :::::::::::::::::::::
CCDS75 DAIPELKASIKKGEDFVKTLK
              220       230 

>>CCDS64691.1 MDH2 gene_id:4191|Hs108|chr7                (296 aa)
 initn: 1890 init1: 977 opt: 980  Z-score: 1236.8  bits: 237.0 E(32554): 1.4e-62
Smith-Waterman score: 1810; 87.3% identity (87.6% similar) in 338 aa overlap (1-338:1-296)

               10        20        30        40        50        60
pF1KE4 MLSALARPVSAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
       ::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 MLSALARPASAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 VATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTF
       :::::::::::::::::::::::                                     
CCDS64 VATLTAACAQHCPEAMICVIANP-------------------------------------
              130       140                                        

              190       200       210       220       230       240
pF1KE4 VAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKA
            :::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 -----GLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKA
                150       160       170       180       190        

              250       260       270       280       290       300
pF1KE4 KAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 KAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIE
      200       210       220       230       240       250        

              310       320       330        
pF1KE4 KNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
       ::::::::::::::::::::::::::::::::::::::
CCDS64 KNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
      260       270       280       290      




338 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 06:27:01 2016 done: Thu Nov  3 06:27:02 2016
 Total Scan time:  2.640 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]