Result of FASTA (omim) for
pFN21AE4324
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4324, 326 aa
1>>>pF1KE4324 326 - 326 aa - 326 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8020+/-0.000361; mu= 15.7742+/- 0.023
mean_var=131.6654+/-27.212, 0's: 0 Z-trim(118.2): 478 B-trim: 1060 in 1/52
Lambda= 0.111773
statistics sampled from 30332 (30864) to 30332 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.362), width: 16
Scan time: 6.720
The best scores are: opt bits E(85289)
NP_001994 (OMIM: 601252) ficolin-1 precursor [Homo ( 326) 2279 378.5 1e-104
XP_011516694 (OMIM: 601624) PREDICTED: ficolin-2 i ( 302) 1422 240.3 3.8e-63
NP_004099 (OMIM: 601624) ficolin-2 isoform a precu ( 313) 1422 240.3 3.9e-63
XP_006717078 (OMIM: 601624) PREDICTED: ficolin-2 i ( 264) 1380 233.5 3.9e-61
NP_056652 (OMIM: 601624) ficolin-2 isoform b precu ( 275) 1380 233.5 4e-61
NP_003656 (OMIM: 604973,613860) ficolin-3 isoform ( 299) 955 165.0 1.8e-40
NP_775628 (OMIM: 604973,613860) ficolin-3 isoform ( 288) 925 160.1 5e-39
NP_116232 (OMIM: 613357) fibrinogen C domain-conta ( 461) 779 136.8 8.3e-32
NP_001138578 (OMIM: 613357) fibrinogen C domain-co ( 461) 779 136.8 8.3e-32
NP_002395 (OMIM: 600596) microfibril-associated gl ( 255) 728 128.3 1.7e-29
NP_001185624 (OMIM: 600596) microfibril-associated ( 279) 728 128.4 1.8e-29
NP_001315564 (OMIM: 601995) tenascin-R isoform 2 [ (1025) 701 124.7 8.5e-28
XP_011508251 (OMIM: 601995) PREDICTED: tenascin-R (1199) 701 124.7 9.4e-28
XP_016857707 (OMIM: 601995) PREDICTED: tenascin-R (1358) 701 124.8 1e-27
NP_003276 (OMIM: 601995) tenascin-R isoform 1 prec (1358) 701 124.8 1e-27
XP_016857708 (OMIM: 601995) PREDICTED: tenascin-R (1358) 701 124.8 1e-27
NP_115859 (OMIM: 600985,606408,615963) tenascin-X ( 673) 670 119.4 2.1e-26
NP_061978 (OMIM: 600985,606408,615963) tenascin-X (4242) 670 120.4 6.8e-26
NP_036230 (OMIM: 605001) angiopoietin-related prot ( 493) 652 116.4 1.3e-25
NP_001300980 (OMIM: 601667) angiopoietin-1 isoform ( 298) 641 114.4 3.1e-25
NP_001186788 (OMIM: 601667) angiopoietin-1 isoform ( 497) 641 114.6 4.3e-25
NP_001137 (OMIM: 601667) angiopoietin-1 isoform 1 ( 498) 641 114.6 4.3e-25
XP_005252032 (OMIM: 187380,615629) PREDICTED: tena (1564) 644 115.7 6.5e-25
XP_005252031 (OMIM: 187380,615629) PREDICTED: tena (1655) 644 115.7 6.8e-25
XP_006717164 (OMIM: 187380,615629) PREDICTED: tena (1655) 644 115.7 6.8e-25
XP_011516930 (OMIM: 187380,615629) PREDICTED: tena (1746) 644 115.7 7e-25
XP_011516931 (OMIM: 187380,615629) PREDICTED: tena (1746) 644 115.7 7e-25
XP_005252030 (OMIM: 187380,615629) PREDICTED: tena (1837) 644 115.8 7.2e-25
XP_011516928 (OMIM: 187380,615629) PREDICTED: tena (1929) 644 115.8 7.5e-25
XP_011516927 (OMIM: 187380,615629) PREDICTED: tena (2019) 644 115.8 7.7e-25
XP_006717161 (OMIM: 187380,615629) PREDICTED: tena (2019) 644 115.8 7.7e-25
XP_016870170 (OMIM: 187380,615629) PREDICTED: tena (2020) 644 115.8 7.7e-25
XP_006717160 (OMIM: 187380,615629) PREDICTED: tena (2110) 644 115.8 7.9e-25
XP_005252029 (OMIM: 187380,615629) PREDICTED: tena (2110) 644 115.8 7.9e-25
NP_002151 (OMIM: 187380,615629) tenascin precursor (2201) 644 115.9 8.1e-25
XP_016870169 (OMIM: 187380,615629) PREDICTED: tena (2292) 644 115.9 8.4e-25
XP_016870168 (OMIM: 187380,615629) PREDICTED: tena (2293) 644 115.9 8.4e-25
XP_006717159 (OMIM: 187380,615629) PREDICTED: tena (2293) 644 115.9 8.4e-25
XP_016870167 (OMIM: 187380,615629) PREDICTED: tena (2384) 644 115.9 8.6e-25
XP_005245634 (OMIM: 603874) PREDICTED: angiopoieti ( 491) 604 108.6 2.7e-23
NP_004664 (OMIM: 603874) angiopoietin-related prot ( 491) 604 108.6 2.7e-23
XP_011527541 (OMIM: 603705) PREDICTED: angiopoieti ( 451) 594 107.0 7.8e-23
NP_057069 (OMIM: 603705) angiopoietin-4 isoform 1 ( 503) 594 107.0 8.4e-23
XP_016868807 (OMIM: 601922) PREDICTED: angiopoieti ( 443) 587 105.9 1.7e-22
NP_001112360 (OMIM: 601922) angiopoietin-2 isoform ( 444) 587 105.9 1.7e-22
NP_001112359 (OMIM: 601922) angiopoietin-2 isoform ( 495) 587 105.9 1.8e-22
NP_001138 (OMIM: 601922) angiopoietin-2 isoform a ( 496) 587 105.9 1.8e-22
NP_114123 (OMIM: 609336) angiopoietin-related prot ( 470) 576 104.1 6e-22
NP_001308340 (OMIM: 609336) angiopoietin-related p ( 470) 576 104.1 6e-22
XP_016882836 (OMIM: 609336) PREDICTED: angiopoieti ( 470) 576 104.1 6e-22
>>NP_001994 (OMIM: 601252) ficolin-1 precursor [Homo sap (326 aa)
initn: 2279 init1: 2279 opt: 2279 Z-score: 2001.1 bits: 378.5 E(85289): 1e-104
Smith-Waterman score: 2279; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326)
10 20 30 40 50 60
pF1KE4 MELSGATMARGLAVLLVLFLHIKNLPAQAADTCPEVKVVGLEGSDKLTILRGCPGLPGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MELSGATMARGLAVLLVLFLHIKNLPAQAADTCPEVKVVGLEGSDKLTILRGCPGLPGAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEKGDAGQSQSCATGPRNCKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEKGDAGQSQSCATGPRNCKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESY
250 260 270 280 290 300
310 320
pF1KE4 ANGINWSAAKGYKYSYKVSEMKVRPA
::::::::::::::::::::::::::
NP_001 ANGINWSAAKGYKYSYKVSEMKVRPA
310 320
>>XP_011516694 (OMIM: 601624) PREDICTED: ficolin-2 isofo (302 aa)
initn: 1420 init1: 1420 opt: 1422 Z-score: 1254.6 bits: 240.3 E(85289): 3.8e-63
Smith-Waterman score: 1679; 77.2% identity (86.4% similar) in 316 aa overlap (11-326:2-302)
10 20 30 40 50 60
pF1KE4 MELSGATMARGLAVLLVLFLHIKNLPAQAADTCPEVKVVGLEGSDKLTILRGCPGLPGAP
: :.: . :: : . :::::::.::::::::::::::::::::::
XP_011 MGPALLALSFLWTMAL---TEDTCPEVKMVGLEGSDKLTILRGCPGLPGAP
10 20 30 40
70 80 90 100 110 120
pF1KE4 GPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEKGDAGQSQSCATGPRNCKD
:::::::. :.::::: :: :::::: ::.: :: : : ::::.:::
XP_011 GPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEP------------QPCLTGPRTCKD
50 60 70 80 90
130 140 150 160 170 180
pF1KE4 LLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFG
:::::.:::::::::::::::::::::::::::::::::::.:::::::::::.::::::
XP_011 LLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFG
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE4 SQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFV
:.::::::::::::::::::.::::::::::: :.:::::.:::::::::::.:::::::
XP_011 SRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE4 GGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESY
::::.::: :::. :::::::::....::: ::::::: .::.::::: :: : : :.
XP_011 EGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSF
220 230 240 250 260 270
310 320
pF1KE4 ANGINWSAAKGYKYSYKVSEMKVRPA
::::::...:::.:::::::::::::
XP_011 ANGINWKSGKGYNYSYKVSEMKVRPA
280 290 300
>>NP_004099 (OMIM: 601624) ficolin-2 isoform a precursor (313 aa)
initn: 1420 init1: 1420 opt: 1422 Z-score: 1254.4 bits: 240.3 E(85289): 3.9e-63
Smith-Waterman score: 1719; 77.0% identity (86.8% similar) in 326 aa overlap (1-326:1-313)
10 20 30 40 50 60
pF1KE4 MELSGATMARGLAVLLVLFLHIKNLPAQAADTCPEVKVVGLEGSDKLTILRGCPGLPGAP
:::. :. . : :.::. :: . ::::::::::.::::::::::::::::::::::
NP_004 MELDRAVGVLGAATLLLSFLGMA-WALQAADTCPEVKMVGLEGSDKLTILRGCPGLPGAP
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 GPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEKGDAGQSQSCATGPRNCKD
:::::::. :.::::: :: :::::: ::.: :: : : ::::.:::
NP_004 GPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEP------------QPCLTGPRTCKD
60 70 80 90 100
130 140 150 160 170 180
pF1KE4 LLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFG
:::::.:::::::::::::::::::::::::::::::::::.:::::::::::.::::::
NP_004 LLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFG
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE4 SQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFV
:.::::::::::::::::::.::::::::::: :.:::::.:::::::::::.:::::::
NP_004 SRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE4 GGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESY
::::.::: :::. :::::::::....::: ::::::: .::.::::: :: : : :.
NP_004 EGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSF
230 240 250 260 270 280
310 320
pF1KE4 ANGINWSAAKGYKYSYKVSEMKVRPA
::::::...:::.:::::::::::::
NP_004 ANGINWKSGKGYNYSYKVSEMKVRPA
290 300 310
>>XP_006717078 (OMIM: 601624) PREDICTED: ficolin-2 isofo (264 aa)
initn: 1371 init1: 1371 opt: 1380 Z-score: 1218.6 bits: 233.5 E(85289): 3.9e-61
Smith-Waterman score: 1401; 78.7% identity (87.8% similar) in 254 aa overlap (73-326:23-264)
50 60 70 80 90 100
pF1KE4 GSDKLTILRGCPGLPGAPGPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEK
:::: :: :::::: ::.: ::
XP_006 MGPALLALSFLWTMALTEDTCPGERGPPGPPGKAGPPGPNGAPGEP------
10 20 30 40
110 120 130 140 150 160
pF1KE4 GDAGQSQSCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRM
: : ::::.::::::::.:::::::::::::::::::::::::::::::::::.
XP_006 ------QPCLTGPRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRV
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 DGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKS
:::::::::::.:::::::.::::::::::::::::::.::::::::::: :.:::::.:
XP_006 DGSVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRS
110 120 130 140 150 160
230 240 250 260 270 280
pF1KE4 FKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYAD
::::::::::.::::::: ::::.::: :::. :::::::::....::: ::::::: .
XP_006 FKVADEAEKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKN
170 180 190 200 210 220
290 300 310 320
pF1KE4 CHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA
::.::::: :: : : :.::::::...:::.:::::::::::::
XP_006 CHVSNLNGRYLRGTHGSFANGINWKSGKGYNYSYKVSEMKVRPA
230 240 250 260
>>NP_056652 (OMIM: 601624) ficolin-2 isoform b precursor (275 aa)
initn: 1410 init1: 1371 opt: 1380 Z-score: 1218.4 bits: 233.5 E(85289): 4e-61
Smith-Waterman score: 1401; 78.7% identity (87.8% similar) in 254 aa overlap (73-326:34-275)
50 60 70 80 90 100
pF1KE4 GSDKLTILRGCPGLPGAPGPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEK
:::: :: :::::: ::.: ::
NP_056 DRAVGVLGAATLLLSFLGMAWALQAADTCPGERGPPGPPGKAGPPGPNGAPGEP------
10 20 30 40 50
110 120 130 140 150 160
pF1KE4 GDAGQSQSCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRM
: : ::::.::::::::.:::::::::::::::::::::::::::::::::::.
NP_056 ------QPCLTGPRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRV
60 70 80 90 100 110
170 180 190 200 210 220
pF1KE4 DGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKS
:::::::::::.:::::::.::::::::::::::::::.::::::::::: :.:::::.:
NP_056 DGSVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRS
120 130 140 150 160 170
230 240 250 260 270 280
pF1KE4 FKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYAD
::::::::::.::::::: ::::.::: :::. :::::::::....::: ::::::: .
NP_056 FKVADEAEKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKN
180 190 200 210 220 230
290 300 310 320
pF1KE4 CHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA
::.::::: :: : : :.::::::...:::.:::::::::::::
NP_056 CHVSNLNGRYLRGTHGSFANGINWKSGKGYNYSYKVSEMKVRPA
240 250 260 270
>>NP_003656 (OMIM: 604973,613860) ficolin-3 isoform 1 pr (299 aa)
initn: 1042 init1: 925 opt: 955 Z-score: 847.6 bits: 165.0 E(85289): 1.8e-40
Smith-Waterman score: 982; 47.0% identity (68.8% similar) in 317 aa overlap (12-324:4-299)
10 20 30 40 50
pF1KE4 MELSGATMARGLAVLLVLFLHIKNLPA----QAADTCPEVKVVGLEGSDKLTILRGCPGL
: .: :.: . . :: : .:: . ::.: :...: .:::
NP_003 MDLLWILPSLWLLLLGGPACLKTQEHPSCPGPRE--LEAS-KVVLLPSCPGA
10 20 30 40
60 70 80 90 100 110
pF1KE4 PGAPGPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEKGDAGQSQSCATGPR
::.:: :: ::: :: :: : : :: : :: . : :::
NP_003 PGSPGEKG---------------APGPQGPPGPPGKMGPKG---EPGDPVNLLRCQEGPR
50 60 70 80 90
120 130 140 150 160 170
pF1KE4 NCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYK
::..::..: ::::. . ::. : : :.:::::.:::: :::::.::::::.:.:..:.
NP_003 NCRELLSQGATLSGWYHLCLPEGRALPVFCDMDTEGGGWLVFQRRQDGSVDFFRSWSSYR
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE4 QGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVL
:::.: .::::::.:.: :: ::. ::::.: ::.::. ::.: .:.. :...:.:.:
NP_003 AGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVDHYQLAL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE4 GAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGP
: : :.::.::. :.. :.: : :.: :.:::: .::::::.:. ::::: : ..
NP_003 GKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNGRYAVSE
220 230 240 250 260 270
300 310 320
pF1KE4 HESYANGINWSAAKGYKYSYKVSEMKVRPA
.. ::.:....: . :. .: .:
NP_003 AAAHKYGIDWASGRGVGHPYRRVRMMLR
280 290
>>NP_775628 (OMIM: 604973,613860) ficolin-3 isoform 2 pr (288 aa)
initn: 1251 init1: 823 opt: 925 Z-score: 821.7 bits: 160.1 E(85289): 5e-39
Smith-Waterman score: 937; 45.7% identity (67.2% similar) in 317 aa overlap (12-324:4-288)
10 20 30 40 50
pF1KE4 MELSGATMARGLAVLLVLFLHIKNLPA----QAADTCPEVKVVGLEGSDKLTILRGCPGL
: .: :.: . . :: : .:: . ::.: :...: .:::
NP_775 MDLLWILPSLWLLLLGGPACLKTQEHPSCPGPRE--LEAS-KVVLLPSCPGA
10 20 30 40
60 70 80 90 100 110
pF1KE4 PGAPGPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEKGDAGQSQSCATGPR
::.:: :: ::: :: :: : : :: :::
NP_775 PGSPGEKG---------------APGPQGPPGPPGKMGPKG--------------EPGPR
50 60 70 80
120 130 140 150 160 170
pF1KE4 NCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYK
::..::..: ::::. . ::. : : :.:::::.:::: :::::.::::::.:.:..:.
NP_775 NCRELLSQGATLSGWYHLCLPEGRALPVFCDMDTEGGGWLVFQRRQDGSVDFFRSWSSYR
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE4 QGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVL
:::.: .::::::.:.: :: ::. ::::.: ::.::. ::.: .:.. :...:.:.:
NP_775 AGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVDHYQLAL
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE4 GAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGP
: : :.::.::. :.. :.: : :.: :.:::: .::::::.:. ::::: : ..
NP_775 GKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNGRYAVSE
210 220 230 240 250 260
300 310 320
pF1KE4 HESYANGINWSAAKGYKYSYKVSEMKVRPA
.. ::.:....: . :. .: .:
NP_775 AAAHKYGIDWASGRGVGHPYRRVRMMLR
270 280
>>NP_116232 (OMIM: 613357) fibrinogen C domain-containin (461 aa)
initn: 734 init1: 365 opt: 779 Z-score: 692.1 bits: 136.8 E(85289): 8.3e-32
Smith-Waterman score: 779; 47.9% identity (68.2% similar) in 261 aa overlap (74-325:210-456)
50 60 70 80 90 100
pF1KE4 SDKLTILRGCPGLPGAPGPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEKG
.::: : : . :.: . :: .
NP_116 GRLIQLLSESQGHMAHLVNSVSDILDALQRDRGL-GRPRN------KADLQRAPARGTR-
180 190 200 210 220 230
110 120 130 140 150
pF1KE4 DAGQSQSCATG--PRNCKDLLDRGYFLSGWHTIYLPDCRP--LTVLCDMDTDGGGWTVFQ
..:::: ::.: :.: : .: .... : : . : ::: ::::::::::
NP_116 ----PRGCATGSRPRDCLDVLLSGQQDDGVYSVF-PTHYPAGFQVYCDMRTDGGGWTVFQ
240 250 260 270 280
160 170 180 190 200 210
pF1KE4 RRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAK
:: ::::.:.: : ::..::: :: ::: :::::.:.. ::.::: :::.. .:.
NP_116 RREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYAR
290 300 310 320 330 340
220 230 240 250 260 270
pF1KE4 YKSFKVA-----DEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKF
: :: :. : . : :... . .:.::.:: :.. :.:::.:.: : .::: .
NP_116 YGSFGVGLFSVDPEEDGYPLTVADY-SGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFY
350 360 370 380 390 400
280 290 300 310 320
pF1KE4 QGAWWYADCHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA
.::::: .::.::::: :: : : :::.:..::. :..:: : ::::.::
NP_116 RGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR
410 420 430 440 450 460
>>NP_001138578 (OMIM: 613357) fibrinogen C domain-contai (461 aa)
initn: 734 init1: 365 opt: 779 Z-score: 692.1 bits: 136.8 E(85289): 8.3e-32
Smith-Waterman score: 779; 47.9% identity (68.2% similar) in 261 aa overlap (74-325:210-456)
50 60 70 80 90 100
pF1KE4 SDKLTILRGCPGLPGAPGPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEKG
.::: : : . :.: . :: .
NP_001 GRLIQLLSESQGHMAHLVNSVSDILDALQRDRGL-GRPRN------KADLQRAPARGTR-
180 190 200 210 220 230
110 120 130 140 150
pF1KE4 DAGQSQSCATG--PRNCKDLLDRGYFLSGWHTIYLPDCRP--LTVLCDMDTDGGGWTVFQ
..:::: ::.: :.: : .: .... : : . : ::: ::::::::::
NP_001 ----PRGCATGSRPRDCLDVLLSGQQDDGVYSVF-PTHYPAGFQVYCDMRTDGGGWTVFQ
240 250 260 270 280
160 170 180 190 200 210
pF1KE4 RRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAK
:: ::::.:.: : ::..::: :: ::: :::::.:.. ::.::: :::.. .:.
NP_001 RREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYAR
290 300 310 320 330 340
220 230 240 250 260 270
pF1KE4 YKSFKVA-----DEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKF
: :: :. : . : :... . .:.::.:: :.. :.:::.:.: : .::: .
NP_001 YGSFGVGLFSVDPEEDGYPLTVADY-SGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFY
350 360 370 380 390 400
280 290 300 310 320
pF1KE4 QGAWWYADCHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA
.::::: .::.::::: :: : : :::.:..::. :..:: : ::::.::
NP_001 RGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR
410 420 430 440 450 460
>>NP_002395 (OMIM: 600596) microfibril-associated glycop (255 aa)
initn: 696 init1: 357 opt: 728 Z-score: 650.6 bits: 128.3 E(85289): 1.7e-29
Smith-Waterman score: 728; 47.9% identity (70.5% similar) in 234 aa overlap (100-326:24-255)
70 80 90 100 110 120
pF1KE4 GERGERGLPGAPGKAGPVGPKGDRGEKGMRGEKGDAGQSQSCATGPRNCKDLLDRGYFLS
: .::: . . : : .: :. .:: .
NP_002 MKALLALPLLLLLSTPPCAPQVSGIRGDALE-RFCLQQPLDCDDIYAQGYQSD
10 20 30 40 50
130 140 150 160 170 180
pF1KE4 GWHTIYLPD--CRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFW
: . :: :. :. :.::: :.:: :::::.:..:::.:.: : :: ::: ::.:
NP_002 GVYLIY-PSGPSVPVPVFCDMTTEGGKWTVFQKRFNGSVSFFRGWNDYKLGFGRADGEYW
60 70 80 90 100 110
190 200 210 220 230 240
pF1KE4 LGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEA-----EKYKLVLGAFVGG
:: .:.: :: . . :::::: :::.: .::: .:... .: . : : ...: :
NP_002 LGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADFSISPNAVSAEEDGYTLFVAGFEDG
120 130 140 150 160 170
250 260 270 280 290 300
pF1KE4 SAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYAN
.::.::. :... ::: :.:.:. .::: .::.:. .:: .::::.:: : : ::::
NP_002 GAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFANLNGFYLGGSHLSYAN
180 190 200 210 220 230
310 320
pF1KE4 GINWSAAKGYKYSYKVSEMKVRPA
::::. ::. :: : .:::.: :
NP_002 GINWAQWKGFYYSLKRTEMKIRRA
240 250
326 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:26:48 2016 done: Mon Nov 7 17:26:49 2016
Total Scan time: 6.720 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]