Result of FASTA (omim) for
pFN21AE4323
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4323, 326 aa
1>>>pF1KE4323 326 - 326 aa - 326 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.2930+/-0.000332; mu= -9.2734+/- 0.021
mean_var=376.0269+/-76.318, 0's: 0 Z-trim(126.4): 8 B-trim: 0 in 0/59
Lambda= 0.066140
statistics sampled from 52319 (52327) to 52319 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.859), E-opt: 0.2 (0.614), width: 16
Scan time: 10.720
The best scores are: opt bits E(85289)
NP_003398 (OMIM: 190700) tristetraprolin [Homo sap ( 332) 2313 233.6 4.4e-61
NP_004917 (OMIM: 601064) zinc finger protein 36, C ( 338) 509 61.5 3e-09
NP_001231627 (OMIM: 601064) zinc finger protein 36 ( 338) 509 61.5 3e-09
NP_001231630 (OMIM: 601064) zinc finger protein 36 ( 407) 509 61.5 3.4e-09
NP_008818 (OMIM: 612053) zinc finger protein 36, C ( 494) 455 56.5 1.4e-07
>>NP_003398 (OMIM: 190700) tristetraprolin [Homo sapiens (332 aa)
initn: 2313 init1: 2313 opt: 2313 Z-score: 1217.6 bits: 233.6 E(85289): 4.4e-61
Smith-Waterman score: 2313; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:7-332)
10 20 30 40 50
pF1KE4 MDLTAIYESLLSLSPDVPVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MANRYTMDLTAIYESLLSLSPDVPVPSDHGGTESSPGWGSSGPWSLSPSDSSPSGVTSRL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 PGRSTSLVEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PGRSTSLVEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 SGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 PGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PGHPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPLSPSAFSA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 APGTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 APGTPLARRDPTPVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEYASSGSSLGGS
250 260 270 280 290 300
300 310 320
pF1KE4 DSPVFEAGVFAPPQPVAAPRRLPIFNRISVSE
::::::::::::::::::::::::::::::::
NP_003 DSPVFEAGVFAPPQPVAAPRRLPIFNRISVSE
310 320 330
>>NP_004917 (OMIM: 601064) zinc finger protein 36, C3H1 (338 aa)
initn: 494 init1: 377 opt: 509 Z-score: 287.2 bits: 61.5 E(85289): 3e-09
Smith-Waterman score: 530; 40.2% identity (56.0% similar) in 266 aa overlap (84-326:95-337)
60 70 80 90 100 110
pF1KE4 LPGRSTSLVEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFS
: .: :. .: . ... ::::::::: :
NP_004 NQLLSSLKGEPAPALSSRDSRFRDRSFSEGGERLLPTQKQPGGGQVNSSRYKTELCRPFE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 ESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLA
:.: :.:: :::::::. :::. .::::::::::. :. : :::: ::::::: : :
NP_004 ENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERRA
130 140 150 160 170 180
180 190 200 210 220
pF1KE4 APG------HPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPL
: : :..:.::.:.::. :. :: ::.: ::: :
NP_004 LAGARDLSADRPRLQHSFSFAGFPSAAATAAAT-GLLD--------SPTSITPPP---IL
190 200 210 220 230
230 240 250 260 270
pF1KE4 SPSAFSAAPGTPLARRDPTPVCCPSCRRATPISVWGPLGG-----LVRT-----------
: . . ..: : . .: :. : :: : :
NP_004 SADDLLGSPTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSP
240 250 260 270 280 290
280 290 300 310 320
pF1KE4 PSVQSLGSDPDEY-ASSGSSLGGSDSPVFEAGVFAPPQPVAAPRRLPIFNRISVSE
:: :. :: . : .::.:: .:::::... . ::::::.:.:.:.
NP_004 PSPQDSLSDQEGYLSSSSSSHSGSDSPTLDNS-----------RRLPIFSRLSISDD
300 310 320 330
>>NP_001231627 (OMIM: 601064) zinc finger protein 36, C3 (338 aa)
initn: 494 init1: 377 opt: 509 Z-score: 287.2 bits: 61.5 E(85289): 3e-09
Smith-Waterman score: 530; 40.2% identity (56.0% similar) in 266 aa overlap (84-326:95-337)
60 70 80 90 100 110
pF1KE4 LPGRSTSLVEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFS
: .: :. .: . ... ::::::::: :
NP_001 NQLLSSLKGEPAPALSSRDSRFRDRSFSEGGERLLPTQKQPGGGQVNSSRYKTELCRPFE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 ESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLA
:.: :.:: :::::::. :::. .::::::::::. :. : :::: ::::::: : :
NP_001 ENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERRA
130 140 150 160 170 180
180 190 200 210 220
pF1KE4 APG------HPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPL
: : :..:.::.:.::. :. :: ::.: ::: :
NP_001 LAGARDLSADRPRLQHSFSFAGFPSAAATAAAT-GLLD--------SPTSITPPP---IL
190 200 210 220 230
230 240 250 260 270
pF1KE4 SPSAFSAAPGTPLARRDPTPVCCPSCRRATPISVWGPLGG-----LVRT-----------
: . . ..: : . .: :. : :: : :
NP_001 SADDLLGSPTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSP
240 250 260 270 280 290
280 290 300 310 320
pF1KE4 PSVQSLGSDPDEY-ASSGSSLGGSDSPVFEAGVFAPPQPVAAPRRLPIFNRISVSE
:: :. :: . : .::.:: .:::::... . ::::::.:.:.:.
NP_001 PSPQDSLSDQEGYLSSSSSSHSGSDSPTLDNS-----------RRLPIFSRLSISDD
300 310 320 330
>>NP_001231630 (OMIM: 601064) zinc finger protein 36, C3 (407 aa)
initn: 494 init1: 377 opt: 509 Z-score: 286.1 bits: 61.5 E(85289): 3.4e-09
Smith-Waterman score: 530; 40.2% identity (56.0% similar) in 266 aa overlap (84-326:164-406)
60 70 80 90 100 110
pF1KE4 LPGRSTSLVEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFS
: .: :. .: . ... ::::::::: :
NP_001 NQLLSSLKGEPAPALSSRDSRFRDRSFSEGGERLLPTQKQPGGGQVNSSRYKTELCRPFE
140 150 160 170 180 190
120 130 140 150 160 170
pF1KE4 ESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLA
:.: :.:: :::::::. :::. .::::::::::. :. : :::: ::::::: : :
NP_001 ENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERRA
200 210 220 230 240 250
180 190 200 210 220
pF1KE4 APG------HPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPL
: : :..:.::.:.::. :. :: ::.: ::: :
NP_001 LAGARDLSADRPRLQHSFSFAGFPSAAATAAAT-GLLD--------SPTSITPPP---IL
260 270 280 290 300
230 240 250 260 270
pF1KE4 SPSAFSAAPGTPLARRDPTPVCCPSCRRATPISVWGPLGG-----LVRT-----------
: . . ..: : . .: :. : :: : :
NP_001 SADDLLGSPTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSP
310 320 330 340 350 360
280 290 300 310 320
pF1KE4 PSVQSLGSDPDEY-ASSGSSLGGSDSPVFEAGVFAPPQPVAAPRRLPIFNRISVSE
:: :. :: . : .::.:: .:::::... . ::::::.:.:.:.
NP_001 PSPQDSLSDQEGYLSSSSSSHSGSDSPTLDNS-----------RRLPIFSRLSISDD
370 380 390 400
>>NP_008818 (OMIM: 612053) zinc finger protein 36, C3H1 (494 aa)
initn: 440 init1: 384 opt: 455 Z-score: 257.1 bits: 56.5 E(85289): 1.4e-07
Smith-Waterman score: 499; 45.6% identity (60.1% similar) in 193 aa overlap (102-267:152-339)
80 90 100 110 120 130
pF1KE4 PPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKCQFAHGLG
.:::::::: : ::: :.:: :::::::.
NP_008 RSFSENGDRSQHLLHLQQQQKGGGGSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGFH
130 140 150 160 170 180
140 150 160 170
pF1KE4 ELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAP----------------
:::. .::::::::::. :. : :::: ::::::: .: ::
NP_008 ELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGGASGDLRAFGTRDA
190 200 210 220 230 240
180 190 200 210 220
pF1KE4 ---GHP----PVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSS-SPPPPGDLPL
: : : :..:.::::.:::.. :: :: .: : .: :.: .::::.
NP_008 LHLGFPREPRPKLHHSLSFSGFPSGHHQ--PPGGLESPLLLDS---PTSRTPPPPSCSSA
250 260 270 280 290
230 240 250 260 270 280
pF1KE4 SPSAFSAAP-GTPLARRDPT--PVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEY
: . ::. .. : :. :.:: : :. .. ::
NP_008 SSCSSSASSCSSASAASTPSGAPTCCASAAAAAAAALLYGTGGAEDLLAPGAPCAACSSA
300 310 320 330 340 350
290 300 310 320
pF1KE4 ASSGSSLGGSDSPVFEAGVFAPPQPVAAPRRLPIFNRISVSE
NP_008 SCANNAFAFGPELSSLITPLAIQTHNFAAVAAAAYYRSQQQQQQQGLAPPAQPPAPPSAT
360 370 380 390 400 410
326 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 06:44:34 2016 done: Thu Nov 3 06:44:35 2016
Total Scan time: 10.720 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]