Result of FASTA (omim) for
pFN21AE4319
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4319, 325 aa
1>>>pF1KE4319 325 - 325 aa - 325 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3864+/-0.000363; mu= 15.5291+/- 0.023
mean_var=70.2915+/-14.311, 0's: 0 Z-trim(113.7): 38 B-trim: 0 in 0/49
Lambda= 0.152976
statistics sampled from 23091 (23129) to 23091 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.271), width: 16
Scan time: 7.830
The best scores are: opt bits E(85289)
NP_001189342 (OMIM: 103830) alcohol dehydrogenase ( 325) 2218 498.6 7.2e-141
NP_001189343 (OMIM: 103830) alcohol dehydrogenase ( 325) 2218 498.6 7.2e-141
NP_006057 (OMIM: 103830) alcohol dehydrogenase [NA ( 325) 2218 498.6 7.2e-141
NP_697021 (OMIM: 103830) alcohol dehydrogenase [NA ( 325) 2218 498.6 7.2e-141
XP_011538794 (OMIM: 103830) PREDICTED: alcohol deh ( 214) 1473 334.1 1.6e-91
XP_011538793 (OMIM: 103830) PREDICTED: alcohol deh ( 214) 1473 334.1 1.6e-91
NP_001619 (OMIM: 103880) aldose reductase isoform ( 316) 1080 247.4 2.8e-65
NP_064695 (OMIM: 604707) aldo-keto reductase famil ( 316) 1055 241.9 1.3e-63
XP_011514543 (OMIM: 616336) PREDICTED: aldo-keto r ( 316) 1016 233.3 5.1e-61
XP_016867713 (OMIM: 616336) PREDICTED: aldo-keto r ( 344) 932 214.8 2.1e-55
NP_001074007 (OMIM: 616336) aldo-keto reductase fa ( 344) 932 214.8 2.1e-55
NP_001344 (OMIM: 600449) aldo-keto reductase famil ( 323) 922 212.6 9.1e-55
NP_995317 (OMIM: 600450,614279) aldo-keto reductas ( 323) 918 211.7 1.7e-54
NP_001345 (OMIM: 600450,614279) aldo-keto reductas ( 323) 918 211.7 1.7e-54
NP_005980 (OMIM: 235555,604741) 3-oxo-5-beta-stero ( 326) 914 210.8 3.1e-54
NP_001809 (OMIM: 600451,614279) aldo-keto reductas ( 323) 906 209.1 1.1e-53
NP_003730 (OMIM: 603966) aldo-keto reductase famil ( 323) 870 201.1 2.6e-51
NP_001240837 (OMIM: 603966) aldo-keto reductase fa ( 323) 866 200.2 4.8e-51
NP_001177836 (OMIM: 235555,604741) 3-oxo-5-beta-st ( 290) 786 182.5 9e-46
XP_011514718 (OMIM: 604707) PREDICTED: aldo-keto r ( 277) 631 148.3 1.7e-35
XP_005250291 (OMIM: 103880) PREDICTED: aldose redu ( 172) 567 134.1 2.1e-31
NP_001333071 (OMIM: 103880) aldose reductase isofo ( 172) 567 134.1 2.1e-31
XP_011514719 (OMIM: 604707) PREDICTED: aldo-keto r ( 175) 497 118.6 9.4e-27
XP_016871280 (OMIM: 600449) PREDICTED: aldo-keto r ( 297) 492 117.7 3.1e-26
NP_001307956 (OMIM: 600450,614279) aldo-keto reduc ( 297) 485 116.1 9.1e-26
NP_001177835 (OMIM: 235555,604741) 3-oxo-5-beta-st ( 285) 418 101.3 2.5e-21
NP_001128713 (OMIM: 600450,614279) aldo-keto reduc ( 139) 356 87.5 1.8e-17
NP_001240838 (OMIM: 603966) aldo-keto reductase fa ( 138) 334 82.6 5.2e-16
>>NP_001189342 (OMIM: 103830) alcohol dehydrogenase [NAD (325 aa)
initn: 2218 init1: 2218 opt: 2218 Z-score: 2650.0 bits: 498.6 E(85289): 7.2e-141
Smith-Waterman score: 2218; 100.0% identity (100.0% similar) in 325 aa overlap (1-325:1-325)
10 20 30 40 50 60
pF1KE4 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV
250 260 270 280 290 300
310 320
pF1KE4 PMLTVDGKRVPRDAGHPLYPFNDPY
:::::::::::::::::::::::::
NP_001 PMLTVDGKRVPRDAGHPLYPFNDPY
310 320
>>NP_001189343 (OMIM: 103830) alcohol dehydrogenase [NAD (325 aa)
initn: 2218 init1: 2218 opt: 2218 Z-score: 2650.0 bits: 498.6 E(85289): 7.2e-141
Smith-Waterman score: 2218; 100.0% identity (100.0% similar) in 325 aa overlap (1-325:1-325)
10 20 30 40 50 60
pF1KE4 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV
250 260 270 280 290 300
310 320
pF1KE4 PMLTVDGKRVPRDAGHPLYPFNDPY
:::::::::::::::::::::::::
NP_001 PMLTVDGKRVPRDAGHPLYPFNDPY
310 320
>>NP_006057 (OMIM: 103830) alcohol dehydrogenase [NADP(+ (325 aa)
initn: 2218 init1: 2218 opt: 2218 Z-score: 2650.0 bits: 498.6 E(85289): 7.2e-141
Smith-Waterman score: 2218; 100.0% identity (100.0% similar) in 325 aa overlap (1-325:1-325)
10 20 30 40 50 60
pF1KE4 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV
250 260 270 280 290 300
310 320
pF1KE4 PMLTVDGKRVPRDAGHPLYPFNDPY
:::::::::::::::::::::::::
NP_006 PMLTVDGKRVPRDAGHPLYPFNDPY
310 320
>>NP_697021 (OMIM: 103830) alcohol dehydrogenase [NADP(+ (325 aa)
initn: 2218 init1: 2218 opt: 2218 Z-score: 2650.0 bits: 498.6 E(85289): 7.2e-141
Smith-Waterman score: 2218; 100.0% identity (100.0% similar) in 325 aa overlap (1-325:1-325)
10 20 30 40 50 60
pF1KE4 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_697 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_697 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_697 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_697 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_697 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV
250 260 270 280 290 300
310 320
pF1KE4 PMLTVDGKRVPRDAGHPLYPFNDPY
:::::::::::::::::::::::::
NP_697 PMLTVDGKRVPRDAGHPLYPFNDPY
310 320
>>XP_011538794 (OMIM: 103830) PREDICTED: alcohol dehydro (214 aa)
initn: 1473 init1: 1473 opt: 1473 Z-score: 1764.1 bits: 334.1 E(85289): 1.6e-91
Smith-Waterman score: 1473; 100.0% identity (100.0% similar) in 214 aa overlap (112-325:1-214)
90 100 110 120 130 140
pF1KE4 WNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYK
::::::::::::::::::::::::::::::
XP_011 MHWPYAFERGDNPFPKNADGTICYDSTHYK
10 20 30
150 160 170 180 190 200
pF1KE4 ETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQ
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE4 ARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICI
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE4 PKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPF
160 170 180 190 200 210
pF1KE4 NDPY
::::
XP_011 NDPY
>>XP_011538793 (OMIM: 103830) PREDICTED: alcohol dehydro (214 aa)
initn: 1473 init1: 1473 opt: 1473 Z-score: 1764.1 bits: 334.1 E(85289): 1.6e-91
Smith-Waterman score: 1473; 100.0% identity (100.0% similar) in 214 aa overlap (112-325:1-214)
90 100 110 120 130 140
pF1KE4 WNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYK
::::::::::::::::::::::::::::::
XP_011 MHWPYAFERGDNPFPKNADGTICYDSTHYK
10 20 30
150 160 170 180 190 200
pF1KE4 ETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQ
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE4 ARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVICI
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE4 PKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPF
160 170 180 190 200 210
pF1KE4 NDPY
::::
XP_011 NDPY
>>NP_001619 (OMIM: 103880) aldose reductase isoform 1 [H (316 aa)
initn: 1076 init1: 484 opt: 1080 Z-score: 1292.8 bits: 247.4 E(85289): 2.8e-65
Smith-Waterman score: 1087; 49.5% identity (75.7% similar) in 325 aa overlap (3-325:2-316)
10 20 30 40 50 60
pF1KE4 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
:: .::..: :::..::::::: :::: ::: :..::::::::: .: :: :.: :.
NP_001 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
.: . ..: :::::..:::: : :. :. : .:::.::.:.::::::.::: .:.
NP_001 QEKLRE-QVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP
60 70 80 90 100 110
130 140 150 160 170
pF1KE4 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR-
: . :: . .:.. ..:. .:: :.: :: .:::.:.:.:::: :.. ::. ...
NP_001 GKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 -PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALA
::: :.::::::.:..:: .::..:. ::::::::: :: : :..: :::.: . :.:
NP_001 KPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY
:.... ::.:.:. .::... ::::.:: :: .:.::::: .: ..: : . :.:::
NP_001 AKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR-
240 250 260 270 280 290
300 310 320
pF1KE4 IVPMLTVDGKRVPRDAGHPLYPFNDPY
. .:. ..: :::.. .
NP_001 VCALLSC--------TSHKDYPFHEEF
300 310
>>NP_064695 (OMIM: 604707) aldo-keto reductase family 1 (316 aa)
initn: 1097 init1: 486 opt: 1055 Z-score: 1263.0 bits: 241.9 E(85289): 1.3e-63
Smith-Waterman score: 1055; 51.5% identity (77.8% similar) in 297 aa overlap (3-297:2-297)
10 20 30 40 50 60
pF1KE4 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
:. : : : :::..::::::: :.:: ::: :...:::::::: .: :: :.:::.
NP_064 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAI
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
.: . ::: ::.::..:::: : . :. :..::: ::.: :::.::.::: .:.
NP_064 QEKIQE-KAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKS
60 70 80 90 100 110
130 140 150 160 170
pF1KE4 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR-
::. :::. :. .. . ..:.:.: :: .:::.:::.:::. ::. .:. ...
NP_064 GDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 -PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALA
:.. ::::::::.:..:: .:...:. ::::::::: :: : :..: :::.: . .:
NP_064 KPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY
:. .. ::.:.:...::.:: ::::.::.::..::.:::: .: ::: . ..:.:::
NP_064 AKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRA
240 250 260 270 280 290
300 310 320
pF1KE4 IVPMLTVDGKRVPRDAGHPLYPFNDPY
NP_064 CNVLQSSHLEDYPFNAEY
300 310
>>XP_011514543 (OMIM: 616336) PREDICTED: aldo-keto reduc (316 aa)
initn: 1034 init1: 471 opt: 1016 Z-score: 1216.5 bits: 233.3 E(85289): 5.1e-61
Smith-Waterman score: 1016; 49.8% identity (77.1% similar) in 297 aa overlap (3-297:2-297)
10 20 30 40 50 60
pF1KE4 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEAL
:. : : : :::..:::::.: :.:: ::: :... ::::::: .: :. :.:::.
XP_011 MATFVELSTKAKMPIVGLGTWRSLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAI
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 KEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER
.: . ::: ::.::..::.: : . :. :..::: ::.: :::.::.::: .:.
XP_011 QEKIQE-KAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKT
60 70 80 90 100 110
130 140 150 160 170
pF1KE4 GDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR-
::. :::. :.. . . ..:.:.: :: .:::.:::.:::: ::. .:. ...
XP_011 GDDFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 -PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALA
:.. ::::::::.:..:: .:...:. ::::::::: :: : :..: :::.: . .:
XP_011 KPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY
:. .. ::.:.:...::.: ::::.::..:..::.:::: .: ::: . ..:.:::
XP_011 AKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRA
240 250 260 270 280 290
300 310 320
pF1KE4 IVPMLTVDGKRVPRDAGHPLYPFNDPY
XP_011 FDFKEFSHLEDFPFDAEY
300 310
>>XP_016867713 (OMIM: 616336) PREDICTED: aldo-keto reduc (344 aa)
initn: 963 init1: 471 opt: 932 Z-score: 1115.8 bits: 214.8 E(85289): 2.1e-55
Smith-Waterman score: 932; 49.5% identity (77.7% similar) in 273 aa overlap (27-297:54-325)
10 20 30 40 50
pF1KE4 MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEI
:.:: ::: :... ::::::: .: :. :.
XP_016 VGPLTGLKSSLLKDTTSAGPLLRPYPASLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEV
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE4 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY
:::..: . ::: ::.::..::.: : . :. :..::: ::.: :::.::.:::
XP_016 GEAIQEKIQE-KAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE4 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA
.:. ::. :::. :.. . . ..:.:.: :: .:::.:::.:::: ::. .:.
XP_016 GFKTGDDFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKP
150 160 170 180 190 200
180 190 200 210 220 230
pF1KE4 SVR--PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVV
... :.. ::::::::.:..:: .:...:. ::::::::: :: : :..: :::.: .
XP_016 GLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKI
210 220 230 240 250 260
240 250 260 270 280 290
pF1KE4 LALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNK
.: :. .. ::.:.:...::.: ::::.::..:..::.:::: .: ::: . ..:.
XP_016 KEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNR
270 280 290 300 310 320
300 310 320
pF1KE4 NWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY
:::
XP_016 NWRAFDFKEFSHLEDFPFDAEY
330 340
325 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:11:56 2016 done: Sat Nov 5 23:11:57 2016
Total Scan time: 7.830 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]