Result of FASTA (omim) for
pFN21AE4316
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4316, 323 aa
1>>>pF1KE4316 323 - 323 aa - 323 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9477+/-0.000372; mu= 17.8100+/- 0.023
mean_var=63.5204+/-13.084, 0's: 0 Z-trim(112.8): 59 B-trim: 0 in 0/52
Lambda= 0.160923
statistics sampled from 21751 (21810) to 21751 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.256), width: 16
Scan time: 7.350
The best scores are: opt bits E(85289)
NP_001344 (OMIM: 600449) aldo-keto reductase famil ( 323) 2173 513.2 2.9e-145
NP_001345 (OMIM: 600450,614279) aldo-keto reductas ( 323) 2123 501.6 9.1e-142
NP_995317 (OMIM: 600450,614279) aldo-keto reductas ( 323) 2123 501.6 9.1e-142
NP_003730 (OMIM: 603966) aldo-keto reductase famil ( 323) 1927 456.1 4.5e-128
NP_001240837 (OMIM: 603966) aldo-keto reductase fa ( 323) 1923 455.1 8.6e-128
NP_001809 (OMIM: 600451,614279) aldo-keto reductas ( 323) 1845 437.0 2.4e-122
NP_005980 (OMIM: 235555,604741) 3-oxo-5-beta-stero ( 326) 1321 315.4 1e-85
XP_016871280 (OMIM: 600449) PREDICTED: aldo-keto r ( 297) 1185 283.8 3.1e-76
NP_001177836 (OMIM: 235555,604741) 3-oxo-5-beta-st ( 290) 1171 280.5 2.8e-75
NP_001307956 (OMIM: 600450,614279) aldo-keto reduc ( 297) 1165 279.1 7.6e-75
NP_001619 (OMIM: 103880) aldose reductase isoform ( 316) 1069 256.9 4.1e-68
NP_064695 (OMIM: 604707) aldo-keto reductase famil ( 316) 1008 242.7 7.5e-64
XP_011514543 (OMIM: 616336) PREDICTED: aldo-keto r ( 316) 971 234.1 2.9e-61
XP_016867713 (OMIM: 616336) PREDICTED: aldo-keto r ( 344) 946 228.3 1.7e-59
NP_001074007 (OMIM: 616336) aldo-keto reductase fa ( 344) 946 228.3 1.7e-59
NP_001189343 (OMIM: 103830) alcohol dehydrogenase ( 325) 922 222.8 7.9e-58
NP_697021 (OMIM: 103830) alcohol dehydrogenase [NA ( 325) 922 222.8 7.9e-58
NP_006057 (OMIM: 103830) alcohol dehydrogenase [NA ( 325) 922 222.8 7.9e-58
NP_001189342 (OMIM: 103830) alcohol dehydrogenase ( 325) 922 222.8 7.9e-58
NP_001128713 (OMIM: 600450,614279) aldo-keto reduc ( 139) 788 191.4 9.3e-49
NP_001240838 (OMIM: 603966) aldo-keto reductase fa ( 138) 728 177.5 1.4e-44
XP_011514718 (OMIM: 604707) PREDICTED: aldo-keto r ( 277) 665 163.0 6.3e-40
NP_001333071 (OMIM: 103880) aldose reductase isofo ( 172) 597 147.1 2.5e-35
XP_005250291 (OMIM: 103880) PREDICTED: aldose redu ( 172) 597 147.1 2.5e-35
NP_001177835 (OMIM: 235555,604741) 3-oxo-5-beta-st ( 285) 585 144.5 2.5e-34
XP_011538794 (OMIM: 103830) PREDICTED: alcohol deh ( 214) 562 139.1 8.2e-33
XP_011538793 (OMIM: 103830) PREDICTED: alcohol deh ( 214) 562 139.1 8.2e-33
XP_011514719 (OMIM: 604707) PREDICTED: aldo-keto r ( 175) 420 106.0 5.8e-23
NP_036199 (OMIM: 608477) aflatoxin B1 aldehyde red ( 331) 176 49.6 1.1e-05
XP_011539348 (OMIM: 608477) PREDICTED: aflatoxin B ( 375) 176 49.6 1.2e-05
NP_003680 (OMIM: 603418) aflatoxin B1 aldehyde red ( 359) 163 46.6 9.4e-05
XP_016856203 (OMIM: 608477) PREDICTED: aflatoxin B ( 304) 139 41.0 0.0039
NP_001307908 (OMIM: 603418) aflatoxin B1 aldehyde ( 324) 136 40.3 0.0067
>>NP_001344 (OMIM: 600449) aldo-keto reductase family 1 (323 aa)
initn: 2173 init1: 2173 opt: 2173 Z-score: 2728.9 bits: 513.2 E(85289): 2.9e-145
Smith-Waterman score: 2173; 100.0% identity (100.0% similar) in 323 aa overlap (1-323:1-323)
10 20 30 40 50 60
pF1KE4 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
250 260 270 280 290 300
310 320
pF1KE4 RNVRYLTLDIFAGPPNYPFSDEY
:::::::::::::::::::::::
NP_001 RNVRYLTLDIFAGPPNYPFSDEY
310 320
>>NP_001345 (OMIM: 600450,614279) aldo-keto reductase fa (323 aa)
initn: 2123 init1: 2123 opt: 2123 Z-score: 2666.2 bits: 501.6 E(85289): 9.1e-142
Smith-Waterman score: 2123; 97.8% identity (99.4% similar) in 323 aa overlap (1-323:1-323)
10 20 30 40 50 60
pF1KE4 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
:::::::::::::::::::::::::::::::::::::.::::::::.::::::.::::::
NP_001 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
NP_001 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP
::::::::::::::::::::::::::::::.::::::::::::::::::.: ::::::::
NP_001 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
250 260 270 280 290 300
310 320
pF1KE4 RNVRYLTLDIFAGPPNYPFSDEY
:::::::::::::::::::::::
NP_001 RNVRYLTLDIFAGPPNYPFSDEY
310 320
>>NP_995317 (OMIM: 600450,614279) aldo-keto reductase fa (323 aa)
initn: 2123 init1: 2123 opt: 2123 Z-score: 2666.2 bits: 501.6 E(85289): 9.1e-142
Smith-Waterman score: 2123; 97.8% identity (99.4% similar) in 323 aa overlap (1-323:1-323)
10 20 30 40 50 60
pF1KE4 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
:::::::::::::::::::::::::::::::::::::.::::::::.::::::.::::::
NP_995 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
NP_995 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP
::::::::::::::::::::::::::::::.::::::::::::::::::.: ::::::::
NP_995 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
250 260 270 280 290 300
310 320
pF1KE4 RNVRYLTLDIFAGPPNYPFSDEY
:::::::::::::::::::::::
NP_995 RNVRYLTLDIFAGPPNYPFSDEY
310 320
>>NP_003730 (OMIM: 603966) aldo-keto reductase family 1 (323 aa)
initn: 1927 init1: 1927 opt: 1927 Z-score: 2420.2 bits: 456.1 E(85289): 4.5e-128
Smith-Waterman score: 1927; 87.9% identity (95.7% similar) in 323 aa overlap (1-323:1-323)
10 20 30 40 50 60
pF1KE4 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
::::.::::::::::::::::::::: :::.:::::.:::::::::::::::::::::::
NP_003 MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
:::::::::::::::::::::::::: . ::::::::::: :::. ::::::::::: :.
NP_003 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP
:.:::::. : :::::..:: ::::.::::.:::::::::::::::::::::::::::::
NP_003 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
::::::::::::::::::. :::::::::::::::::::::.:.. ::::::::::::::
NP_003 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
:::::::::::::::::::::::::::::::::::::::::::::::::.:.:::::::.
NP_003 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD
250 260 270 280 290 300
310 320
pF1KE4 RNVRYLTLDIFAGPPNYPFSDEY
::..:.. : ::. ::::.::::
NP_003 RNLHYFNSDSFASHPNYPYSDEY
310 320
>>NP_001240837 (OMIM: 603966) aldo-keto reductase family (323 aa)
initn: 1923 init1: 1923 opt: 1923 Z-score: 2415.2 bits: 455.1 E(85289): 8.6e-128
Smith-Waterman score: 1923; 87.6% identity (95.7% similar) in 323 aa overlap (1-323:1-323)
10 20 30 40 50 60
pF1KE4 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
::::.::.:::::::::::::::::: :::.:::::.:::::::::::::::::::::::
NP_001 MDSKHQCLKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
:::::::::::::::::::::::::: . ::::::::::: :::. ::::::::::: :.
NP_001 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP
:.:::::. : :::::..:: ::::.::::.:::::::::::::::::::::::::::::
NP_001 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
::::::::::::::::::. :::::::::::::::::::::.:.. ::::::::::::::
NP_001 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
:::::::::::::::::::::::::::::::::::::::::::::::::.:.:::::::.
NP_001 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD
250 260 270 280 290 300
310 320
pF1KE4 RNVRYLTLDIFAGPPNYPFSDEY
::..:.. : ::. ::::.::::
NP_001 RNLHYFNSDSFASHPNYPYSDEY
310 320
>>NP_001809 (OMIM: 600451,614279) aldo-keto reductase fa (323 aa)
initn: 1845 init1: 1845 opt: 1845 Z-score: 2317.4 bits: 437.0 E(85289): 2.4e-122
Smith-Waterman score: 1845; 83.0% identity (95.0% similar) in 323 aa overlap (1-323:1-323)
10 20 30 40 50 60
pF1KE4 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
:: ::: :.::::::::::::::::: :::...:.:.:::::::::::::::.:::::::
NP_001 MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
:::::::::::::::::::::::::::. .:..:.:::: :::.::::::::::.:::.
NP_001 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP
..:::: .:::::::..:::::: ::::..:::::::::::::::::: ::::::::::
NP_001 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
::::::::::::::::.:: :::::::::::::::.::::..:.. ::::::::::::::
NP_001 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
::::::::::::::::::::::::::::::::::::::.:.::::::::::.::..::::
NP_001 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN
250 260 270 280 290 300
310 320
pF1KE4 RNVRYLTLDIFAGPPNYPFSDEY
:: ::...:.. :.:::::::
NP_001 RNYRYVVMDFLMDHPDYPFSDEY
310 320
>>NP_005980 (OMIM: 235555,604741) 3-oxo-5-beta-steroid 4 (326 aa)
initn: 1310 init1: 1261 opt: 1321 Z-score: 1659.8 bits: 315.4 E(85289): 1e-85
Smith-Waterman score: 1321; 58.7% identity (85.2% similar) in 317 aa overlap (8-323:10-326)
10 20 30 40 50
pF1KE4 MDSKYQCVKLNDGHFMPVLGFGTYA-PAEVPKSKALEATKLAIEAGFRHIDSAHLYNN
. :.::. .:..:.:::. : .::. ..:.::..:.::::.:..:.:
NP_005 MDLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 EEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIH
:..:: ::: :::.:.:.:::::: .::: ..: ::.:::.:::.:. :::::::::.:.
NP_005 EHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 FPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMIL
:.. :::.:. :.::::: :. .:::::::.: ::::::.::.:::::::::::.::
NP_005 VPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELIL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 NKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLE
::::::.::: :::::::::.: ::: ::...:::..::: ::. :. ::. .:: ::.
NP_005 NKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 DPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAID
: .: .:.:....: : :.::...::::::. ::.: .::..: :.:.:.:: :::: :.
NP_005 DALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIE
250 260 270 280 290 300
300 310 320
pF1KE4 GLNRNVRYLTLDIFAGPPNYPFSDEY
.::.:::.. : .. :.::: :::
NP_005 ALNKNVRFVELLMWRDHPEYPFHDEY
310 320
>>XP_016871280 (OMIM: 600449) PREDICTED: aldo-keto reduc (297 aa)
initn: 1172 init1: 1172 opt: 1185 Z-score: 1489.8 bits: 283.8 E(85289): 3.1e-76
Smith-Waterman score: 1927; 92.0% identity (92.0% similar) in 323 aa overlap (1-323:1-297)
10 20 30 40 50 60
pF1KE4 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP
::: :::::::::::::::::::::::::::::::
XP_016 SVK--------------------------AVEKCKDAGLAKSIGVSNFNRRQLEMILNKP
130 140 150
190 200 210 220 230 240
pF1KE4 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE4 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
220 230 240 250 260 270
310 320
pF1KE4 RNVRYLTLDIFAGPPNYPFSDEY
:::::::::::::::::::::::
XP_016 RNVRYLTLDIFAGPPNYPFSDEY
280 290
>>NP_001177836 (OMIM: 235555,604741) 3-oxo-5-beta-steroi (290 aa)
initn: 1160 init1: 1111 opt: 1171 Z-score: 1472.4 bits: 280.5 E(85289): 2.8e-75
Smith-Waterman score: 1171; 59.6% identity (85.9% similar) in 277 aa overlap (8-283:10-286)
10 20 30 40 50
pF1KE4 MDSKYQCVKLNDGHFMPVLGFGTYA-PAEVPKSKALEATKLAIEAGFRHIDSAHLYNN
. :.::. .:..:.:::. : .::. ..:.::..:.::::.:..:.:
NP_001 MDLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 EEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIH
:..:: ::: :::.:.:.:::::: .::: ..: ::.:::.:::.:. :::::::::.:.
NP_001 EHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 FPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMIL
:.. :::.:. :.::::: :. .:::::::.: ::::::.::.:::::::::::.::
NP_001 VPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELIL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 NKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLE
::::::.::: :::::::::.: ::: ::...:::..::: ::. :. ::. .:: ::.
NP_001 NKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 DPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAID
: .: .:.:....: : :.::...::::::. ::.: .::..: ::
NP_001 DALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQVARSS
250 260 270 280 290
300 310 320
pF1KE4 GLNRNVRYLTLDIFAGPPNYPFSDEY
>>NP_001307956 (OMIM: 600450,614279) aldo-keto reductase (297 aa)
initn: 1152 init1: 1152 opt: 1165 Z-score: 1464.7 bits: 279.1 E(85289): 7.6e-75
Smith-Waterman score: 1877; 89.8% identity (91.3% similar) in 323 aa overlap (1-323:1-297)
10 20 30 40 50 60
pF1KE4 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
:::::::::::::::::::::::::::::::::::::.::::::::.::::::.::::::
NP_001 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
NP_001 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP
::: :.::::::::::::::::::.: ::::::::
NP_001 SVK--------------------------AMEKCKDAGLAKSIGVSNFNHRLLEMILNKP
130 140 150
190 200 210 220 230 240
pF1KE4 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE4 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
220 230 240 250 260 270
310 320
pF1KE4 RNVRYLTLDIFAGPPNYPFSDEY
:::::::::::::::::::::::
NP_001 RNVRYLTLDIFAGPPNYPFSDEY
280 290
323 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:13:36 2016 done: Sat Nov 5 23:13:37 2016
Total Scan time: 7.350 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]