Result of FASTA (omim) for
pFN21AE4308
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4308, 318 aa
1>>>pF1KE4308 318 - 318 aa - 318 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0165+/-0.000341; mu= 17.2824+/- 0.021
mean_var=63.1460+/-12.766, 0's: 0 Z-trim(115.0): 126 B-trim: 78 in 1/55
Lambda= 0.161399
statistics sampled from 25116 (25248) to 25116 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.296), width: 16
Scan time: 8.140
The best scores are: opt bits E(85289)
NP_001186700 (OMIM: 136880,601617) 11-cis retinol ( 318) 2133 505.1 7.5e-143
NP_002896 (OMIM: 136880,601617) 11-cis retinol deh ( 318) 2133 505.1 7.5e-143
XP_005269265 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 1059 255.0 1.4e-67
XP_011537227 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 1059 255.0 1.4e-67
XP_006719735 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 1059 255.0 1.4e-67
XP_005269266 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 1059 255.0 1.4e-67
XP_011537228 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 1059 255.0 1.4e-67
XP_005269264 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 1059 255.0 1.4e-67
XP_011537229 (OMIM: 606623) PREDICTED: 17-beta-hyd ( 317) 1059 255.0 1.4e-67
NP_003716 (OMIM: 606623) 17-beta-hydroxysteroid de ( 317) 1059 255.0 1.4e-67
NP_683695 (OMIM: 609769) short-chain dehydrogenase ( 313) 999 241.1 2.3e-63
NP_954674 (OMIM: 612131) dehydrogenase/reductase S ( 319) 923 223.4 4.9e-58
NP_001135742 (OMIM: 612131) dehydrogenase/reductas ( 319) 923 223.4 4.9e-58
XP_011508777 (OMIM: 612131) PREDICTED: dehydrogena ( 319) 923 223.4 4.9e-58
NP_001135743 (OMIM: 612131) dehydrogenase/reductas ( 319) 923 223.4 4.9e-58
NP_001276692 (OMIM: 612131) dehydrogenase/reductas ( 379) 923 223.4 5.7e-58
XP_016862501 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330) 605 149.3 9.9e-36
XP_016862500 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330) 605 149.3 9.9e-36
XP_016862497 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330) 605 149.3 9.9e-36
XP_011511369 (OMIM: 603063) PREDICTED: D-beta-hydr ( 347) 605 149.4 1e-35
XP_016862499 (OMIM: 603063) PREDICTED: D-beta-hydr ( 324) 604 149.1 1.1e-35
XP_016862498 (OMIM: 603063) PREDICTED: D-beta-hydr ( 324) 604 149.1 1.1e-35
XP_016862496 (OMIM: 603063) PREDICTED: D-beta-hydr ( 343) 604 149.1 1.2e-35
NP_004042 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343) 604 149.1 1.2e-35
XP_005269409 (OMIM: 603063) PREDICTED: D-beta-hydr ( 343) 604 149.1 1.2e-35
NP_976059 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343) 604 149.1 1.2e-35
NP_976060 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343) 604 149.1 1.2e-35
NP_000187 (OMIM: 218030,614232) corticosteroid 11- ( 405) 534 132.9 1.1e-30
NP_002144 (OMIM: 109685) estradiol 17-beta-dehydro ( 387) 520 129.6 1e-29
XP_016862504 (OMIM: 603063) PREDICTED: D-beta-hydr ( 206) 428 108.0 1.7e-23
XP_005269412 (OMIM: 603063) PREDICTED: D-beta-hydr ( 206) 428 108.0 1.7e-23
XP_016862503 (OMIM: 603063) PREDICTED: D-beta-hydr ( 206) 428 108.0 1.7e-23
NP_056540 (OMIM: 608575) retinol dehydrogenase 8 [ ( 331) 304 79.3 1.2e-14
NP_000404 (OMIM: 109684) estradiol 17-beta-dehydro ( 328) 278 73.2 8.2e-13
NP_001317088 (OMIM: 616160) dehydrogenase/reductas ( 310) 266 70.4 5.4e-12
NP_056325 (OMIM: 616160) dehydrogenase/reductase S ( 325) 266 70.4 5.6e-12
XP_016879915 (OMIM: 616160) PREDICTED: dehydrogena ( 325) 266 70.4 5.6e-12
NP_001317148 (OMIM: 109684) estradiol 17-beta-dehy ( 329) 266 70.4 5.7e-12
XP_011522088 (OMIM: 616160) PREDICTED: dehydrogena ( 334) 266 70.4 5.8e-12
XP_005256652 (OMIM: 616160) PREDICTED: dehydrogena ( 372) 266 70.4 6.3e-12
XP_016879914 (OMIM: 616160) PREDICTED: dehydrogena ( 372) 266 70.4 6.3e-12
XP_011523032 (OMIM: 109684) PREDICTED: estradiol 1 ( 383) 263 69.8 1e-11
NP_057113 (OMIM: 612833) dehydrogenase/reductase S ( 339) 257 68.3 2.5e-11
XP_016876857 (OMIM: 612833) PREDICTED: dehydrogena ( 404) 257 68.4 2.9e-11
NP_620419 (OMIM: 608989) epidermal retinol dehydro ( 309) 254 67.6 3.8e-11
NP_001304978 (OMIM: 608989) epidermal retinol dehy ( 318) 254 67.6 3.8e-11
XP_011523031 (OMIM: 109684) PREDICTED: estradiol 1 ( 384) 251 67.0 7.3e-11
NP_001309209 (OMIM: 612833) dehydrogenase/reductas ( 289) 235 63.2 7.6e-10
XP_005257349 (OMIM: 109684) PREDICTED: estradiol 1 ( 359) 232 62.5 1.5e-09
NP_057329 (OMIM: 612831) estradiol 17-beta-dehydro ( 300) 229 61.8 2.1e-09
>>NP_001186700 (OMIM: 136880,601617) 11-cis retinol dehy (318 aa)
initn: 2133 init1: 2133 opt: 2133 Z-score: 2685.6 bits: 505.1 E(85289): 7.5e-143
Smith-Waterman score: 2133; 99.7% identity (100.0% similar) in 318 aa overlap (1-318:1-318)
10 20 30 40 50 60
pF1KE4 MWLPLLLGALLWAVLWLLRDRQSLPASNALVFITGCDSGFGRLLALQLDQRGFRVLASCL
:::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
NP_001 MWLPLLLGALLWAVLWLLRDRQSLPASNAFVFITGCDSGFGRLLALQLDQRGFRVLASCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 TPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSKF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQAHYGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQAHYGGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 FLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPAS
250 260 270 280 290 300
310
pF1KE4 LVDAVLTWVLPKPAQAVY
::::::::::::::::::
NP_001 LVDAVLTWVLPKPAQAVY
310
>>NP_002896 (OMIM: 136880,601617) 11-cis retinol dehydro (318 aa)
initn: 2133 init1: 2133 opt: 2133 Z-score: 2685.6 bits: 505.1 E(85289): 7.5e-143
Smith-Waterman score: 2133; 99.7% identity (100.0% similar) in 318 aa overlap (1-318:1-318)
10 20 30 40 50 60
pF1KE4 MWLPLLLGALLWAVLWLLRDRQSLPASNALVFITGCDSGFGRLLALQLDQRGFRVLASCL
:::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
NP_002 MWLPLLLGALLWAVLWLLRDRQSLPASNAFVFITGCDSGFGRLLALQLDQRGFRVLASCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 TPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSKF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQAHYGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQAHYGGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 FLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYLPAS
250 260 270 280 290 300
310
pF1KE4 LVDAVLTWVLPKPAQAVY
::::::::::::::::::
NP_002 LVDAVLTWVLPKPAQAVY
310
>>XP_005269265 (OMIM: 606623) PREDICTED: 17-beta-hydroxy (317 aa)
initn: 1085 init1: 761 opt: 1059 Z-score: 1334.1 bits: 255.0 E(85289): 1.4e-67
Smith-Waterman score: 1059; 51.6% identity (75.3% similar) in 320 aa overlap (1-317:1-317)
10 20 30 40 50
pF1KE4 MWLPLLLGALLWAVLWLLRDRQSLPA-SNALVFITGCDSGFGRLLALQLDQRGFRVLASC
::: : . :. .: :.:: . .. ::::::::::: ::: ::: ::.::::.:
XP_005 MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 LTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIG
:: .:::.:. .:.::.:. ::.: .:. :..::. :: . ::.:::::::. :
XP_005 LTEKGAEQLRGQTSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 PTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSK
::. .: . .:.:: .: : :::..:::...::::..:..:.:::.: :::::::
XP_005 LCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 FGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNL-ESLEKTLQACWARLPPATQAHYG
.:.::::: :::.. :::...::::::.::: .::. .:::. :. : . : . ::
XP_005 YGVEAFSDILRREIQHFGVKISIVEPGYFRTGMTNMTQSLERMKQS-WKEAPKHIKETYG
190 200 210 220 230
240 250 260 270 280 290
pF1KE4 GAFLTK-YLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYL
.. : :.. ..: :. .:. :. :.:::::. ::::::: :::::....: :::
XP_005 QQYFDALYNIMKEGLLN--CSTNLNLVTDCMEHALTSVHPRTRYSAGWDAKFFFIPLSYL
240 250 260 270 280 290
300 310
pF1KE4 PASLVDAVLTWVLPKPAQAVY
:.::.: .:: :::::::
XP_005 PTSLADYILTRSWPKPAQAV
300 310
>>XP_011537227 (OMIM: 606623) PREDICTED: 17-beta-hydroxy (317 aa)
initn: 1085 init1: 761 opt: 1059 Z-score: 1334.1 bits: 255.0 E(85289): 1.4e-67
Smith-Waterman score: 1059; 51.6% identity (75.3% similar) in 320 aa overlap (1-317:1-317)
10 20 30 40 50
pF1KE4 MWLPLLLGALLWAVLWLLRDRQSLPA-SNALVFITGCDSGFGRLLALQLDQRGFRVLASC
::: : . :. .: :.:: . .. ::::::::::: ::: ::: ::.::::.:
XP_011 MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 LTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIG
:: .:::.:. .:.::.:. ::.: .:. :..::. :: . ::.:::::::. :
XP_011 LTEKGAEQLRGQTSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 PTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSK
::. .: . .:.:: .: : :::..:::...::::..:..:.:::.: :::::::
XP_011 LCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 FGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNL-ESLEKTLQACWARLPPATQAHYG
.:.::::: :::.. :::...::::::.::: .::. .:::. :. : . : . ::
XP_011 YGVEAFSDILRREIQHFGVKISIVEPGYFRTGMTNMTQSLERMKQS-WKEAPKHIKETYG
190 200 210 220 230
240 250 260 270 280 290
pF1KE4 GAFLTK-YLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYL
.. : :.. ..: :. .:. :. :.:::::. ::::::: :::::....: :::
XP_011 QQYFDALYNIMKEGLLN--CSTNLNLVTDCMEHALTSVHPRTRYSAGWDAKFFFIPLSYL
240 250 260 270 280 290
300 310
pF1KE4 PASLVDAVLTWVLPKPAQAVY
:.::.: .:: :::::::
XP_011 PTSLADYILTRSWPKPAQAV
300 310
>>XP_006719735 (OMIM: 606623) PREDICTED: 17-beta-hydroxy (317 aa)
initn: 1085 init1: 761 opt: 1059 Z-score: 1334.1 bits: 255.0 E(85289): 1.4e-67
Smith-Waterman score: 1059; 51.6% identity (75.3% similar) in 320 aa overlap (1-317:1-317)
10 20 30 40 50
pF1KE4 MWLPLLLGALLWAVLWLLRDRQSLPA-SNALVFITGCDSGFGRLLALQLDQRGFRVLASC
::: : . :. .: :.:: . .. ::::::::::: ::: ::: ::.::::.:
XP_006 MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 LTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIG
:: .:::.:. .:.::.:. ::.: .:. :..::. :: . ::.:::::::. :
XP_006 LTEKGAEQLRGQTSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 PTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSK
::. .: . .:.:: .: : :::..:::...::::..:..:.:::.: :::::::
XP_006 LCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 FGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNL-ESLEKTLQACWARLPPATQAHYG
.:.::::: :::.. :::...::::::.::: .::. .:::. :. : . : . ::
XP_006 YGVEAFSDILRREIQHFGVKISIVEPGYFRTGMTNMTQSLERMKQS-WKEAPKHIKETYG
190 200 210 220 230
240 250 260 270 280 290
pF1KE4 GAFLTK-YLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYL
.. : :.. ..: :. .:. :. :.:::::. ::::::: :::::....: :::
XP_006 QQYFDALYNIMKEGLLN--CSTNLNLVTDCMEHALTSVHPRTRYSAGWDAKFFFIPLSYL
240 250 260 270 280 290
300 310
pF1KE4 PASLVDAVLTWVLPKPAQAVY
:.::.: .:: :::::::
XP_006 PTSLADYILTRSWPKPAQAV
300 310
>>XP_005269266 (OMIM: 606623) PREDICTED: 17-beta-hydroxy (317 aa)
initn: 1085 init1: 761 opt: 1059 Z-score: 1334.1 bits: 255.0 E(85289): 1.4e-67
Smith-Waterman score: 1059; 51.6% identity (75.3% similar) in 320 aa overlap (1-317:1-317)
10 20 30 40 50
pF1KE4 MWLPLLLGALLWAVLWLLRDRQSLPA-SNALVFITGCDSGFGRLLALQLDQRGFRVLASC
::: : . :. .: :.:: . .. ::::::::::: ::: ::: ::.::::.:
XP_005 MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 LTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIG
:: .:::.:. .:.::.:. ::.: .:. :..::. :: . ::.:::::::. :
XP_005 LTEKGAEQLRGQTSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 PTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSK
::. .: . .:.:: .: : :::..:::...::::..:..:.:::.: :::::::
XP_005 LCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 FGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNL-ESLEKTLQACWARLPPATQAHYG
.:.::::: :::.. :::...::::::.::: .::. .:::. :. : . : . ::
XP_005 YGVEAFSDILRREIQHFGVKISIVEPGYFRTGMTNMTQSLERMKQS-WKEAPKHIKETYG
190 200 210 220 230
240 250 260 270 280 290
pF1KE4 GAFLTK-YLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYL
.. : :.. ..: :. .:. :. :.:::::. ::::::: :::::....: :::
XP_005 QQYFDALYNIMKEGLLN--CSTNLNLVTDCMEHALTSVHPRTRYSAGWDAKFFFIPLSYL
240 250 260 270 280 290
300 310
pF1KE4 PASLVDAVLTWVLPKPAQAVY
:.::.: .:: :::::::
XP_005 PTSLADYILTRSWPKPAQAV
300 310
>>XP_011537228 (OMIM: 606623) PREDICTED: 17-beta-hydroxy (317 aa)
initn: 1085 init1: 761 opt: 1059 Z-score: 1334.1 bits: 255.0 E(85289): 1.4e-67
Smith-Waterman score: 1059; 51.6% identity (75.3% similar) in 320 aa overlap (1-317:1-317)
10 20 30 40 50
pF1KE4 MWLPLLLGALLWAVLWLLRDRQSLPA-SNALVFITGCDSGFGRLLALQLDQRGFRVLASC
::: : . :. .: :.:: . .. ::::::::::: ::: ::: ::.::::.:
XP_011 MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 LTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIG
:: .:::.:. .:.::.:. ::.: .:. :..::. :: . ::.:::::::. :
XP_011 LTEKGAEQLRGQTSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 PTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSK
::. .: . .:.:: .: : :::..:::...::::..:..:.:::.: :::::::
XP_011 LCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 FGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNL-ESLEKTLQACWARLPPATQAHYG
.:.::::: :::.. :::...::::::.::: .::. .:::. :. : . : . ::
XP_011 YGVEAFSDILRREIQHFGVKISIVEPGYFRTGMTNMTQSLERMKQS-WKEAPKHIKETYG
190 200 210 220 230
240 250 260 270 280 290
pF1KE4 GAFLTK-YLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYL
.. : :.. ..: :. .:. :. :.:::::. ::::::: :::::....: :::
XP_011 QQYFDALYNIMKEGLLN--CSTNLNLVTDCMEHALTSVHPRTRYSAGWDAKFFFIPLSYL
240 250 260 270 280 290
300 310
pF1KE4 PASLVDAVLTWVLPKPAQAVY
:.::.: .:: :::::::
XP_011 PTSLADYILTRSWPKPAQAV
300 310
>>XP_005269264 (OMIM: 606623) PREDICTED: 17-beta-hydroxy (317 aa)
initn: 1085 init1: 761 opt: 1059 Z-score: 1334.1 bits: 255.0 E(85289): 1.4e-67
Smith-Waterman score: 1059; 51.6% identity (75.3% similar) in 320 aa overlap (1-317:1-317)
10 20 30 40 50
pF1KE4 MWLPLLLGALLWAVLWLLRDRQSLPA-SNALVFITGCDSGFGRLLALQLDQRGFRVLASC
::: : . :. .: :.:: . .. ::::::::::: ::: ::: ::.::::.:
XP_005 MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 LTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIG
:: .:::.:. .:.::.:. ::.: .:. :..::. :: . ::.:::::::. :
XP_005 LTEKGAEQLRGQTSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 PTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSK
::. .: . .:.:: .: : :::..:::...::::..:..:.:::.: :::::::
XP_005 LCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 FGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNL-ESLEKTLQACWARLPPATQAHYG
.:.::::: :::.. :::...::::::.::: .::. .:::. :. : . : . ::
XP_005 YGVEAFSDILRREIQHFGVKISIVEPGYFRTGMTNMTQSLERMKQS-WKEAPKHIKETYG
190 200 210 220 230
240 250 260 270 280 290
pF1KE4 GAFLTK-YLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYL
.. : :.. ..: :. .:. :. :.:::::. ::::::: :::::....: :::
XP_005 QQYFDALYNIMKEGLLN--CSTNLNLVTDCMEHALTSVHPRTRYSAGWDAKFFFIPLSYL
240 250 260 270 280 290
300 310
pF1KE4 PASLVDAVLTWVLPKPAQAVY
:.::.: .:: :::::::
XP_005 PTSLADYILTRSWPKPAQAV
300 310
>>XP_011537229 (OMIM: 606623) PREDICTED: 17-beta-hydroxy (317 aa)
initn: 1085 init1: 761 opt: 1059 Z-score: 1334.1 bits: 255.0 E(85289): 1.4e-67
Smith-Waterman score: 1059; 51.6% identity (75.3% similar) in 320 aa overlap (1-317:1-317)
10 20 30 40 50
pF1KE4 MWLPLLLGALLWAVLWLLRDRQSLPA-SNALVFITGCDSGFGRLLALQLDQRGFRVLASC
::: : . :. .: :.:: . .. ::::::::::: ::: ::: ::.::::.:
XP_011 MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 LTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIG
:: .:::.:. .:.::.:. ::.: .:. :..::. :: . ::.:::::::. :
XP_011 LTEKGAEQLRGQTSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 PTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSK
::. .: . .:.:: .: : :::..:::...::::..:..:.:::.: :::::::
XP_011 LCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 FGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNL-ESLEKTLQACWARLPPATQAHYG
.:.::::: :::.. :::...::::::.::: .::. .:::. :. : . : . ::
XP_011 YGVEAFSDILRREIQHFGVKISIVEPGYFRTGMTNMTQSLERMKQS-WKEAPKHIKETYG
190 200 210 220 230
240 250 260 270 280 290
pF1KE4 GAFLTK-YLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYL
.. : :.. ..: :. .:. :. :.:::::. ::::::: :::::....: :::
XP_011 QQYFDALYNIMKEGLLN--CSTNLNLVTDCMEHALTSVHPRTRYSAGWDAKFFFIPLSYL
240 250 260 270 280 290
300 310
pF1KE4 PASLVDAVLTWVLPKPAQAVY
:.::.: .:: :::::::
XP_011 PTSLADYILTRSWPKPAQAV
300 310
>>NP_003716 (OMIM: 606623) 17-beta-hydroxysteroid dehydr (317 aa)
initn: 1085 init1: 761 opt: 1059 Z-score: 1334.1 bits: 255.0 E(85289): 1.4e-67
Smith-Waterman score: 1059; 51.6% identity (75.3% similar) in 320 aa overlap (1-317:1-317)
10 20 30 40 50
pF1KE4 MWLPLLLGALLWAVLWLLRDRQSLPA-SNALVFITGCDSGFGRLLALQLDQRGFRVLASC
::: : . :. .: :.:: . .. ::::::::::: ::: ::: ::.::::.:
NP_003 MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 LTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIG
:: .:::.:. .:.::.:. ::.: .:. :..::. :: . ::.:::::::. :
NP_003 LTEKGAEQLRGQTSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 PTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSK
::. .: . .:.:: .: : :::..:::...::::..:..:.:::.: :::::::
NP_003 LCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 FGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNL-ESLEKTLQACWARLPPATQAHYG
.:.::::: :::.. :::...::::::.::: .::. .:::. :. : . : . ::
NP_003 YGVEAFSDILRREIQHFGVKISIVEPGYFRTGMTNMTQSLERMKQS-WKEAPKHIKETYG
190 200 210 220 230
240 250 260 270 280 290
pF1KE4 GAFLTK-YLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLLWLPASYL
.. : :.. ..: :. .:. :. :.:::::. ::::::: :::::....: :::
NP_003 QQYFDALYNIMKEGLLN--CSTNLNLVTDCMEHALTSVHPRTRYSAGWDAKFFFIPLSYL
240 250 260 270 280 290
300 310
pF1KE4 PASLVDAVLTWVLPKPAQAVY
:.::.: .:: :::::::
NP_003 PTSLADYILTRSWPKPAQAV
300 310
318 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:27:00 2016 done: Sat Nov 5 23:27:01 2016
Total Scan time: 8.140 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]