Result of FASTA (ccds) for
pFN21AE4305
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4305, 305 aa
1>>>pF1KE4305 305 - 305 aa - 305 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1655+/-0.000847; mu= 16.0925+/- 0.050
mean_var=64.9184+/-13.017, 0's: 0 Z-trim(106.7): 33 B-trim: 0 in 0/48
Lambda= 0.159181
statistics sampled from 9134 (9163) to 9134 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.655), E-opt: 0.2 (0.281), width: 16
Scan time: 2.440
The best scores are: opt bits E(32554)
CCDS3296.1 CLDN16 gene_id:10686|Hs108|chr3 ( 305) 2111 493.5 8.5e-140
CCDS11096.1 CLDN7 gene_id:1366|Hs108|chr17 ( 211) 292 75.6 3.5e-14
CCDS3295.1 CLDN1 gene_id:9076|Hs108|chr3 ( 211) 280 72.9 2.4e-13
CCDS5717.1 CLDN15 gene_id:24146|Hs108|chr7 ( 228) 259 68.1 7.2e-12
>>CCDS3296.1 CLDN16 gene_id:10686|Hs108|chr3 (305 aa)
initn: 2111 init1: 2111 opt: 2111 Z-score: 2623.3 bits: 493.5 E(32554): 8.5e-140
Smith-Waterman score: 2111; 100.0% identity (100.0% similar) in 305 aa overlap (1-305:1-305)
10 20 30 40 50 60
pF1KE4 MTSRTPLLVTACLYYSYCNSRHLQQGVRKSKRPVFSHCQVPETQKTDTRHLSGARAGVCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 MTSRTPLLVTACLYYSYCNSRHLQQGVRKSKRPVFSHCQVPETQKTDTRHLSGARAGVCP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 CCHPDGLLATMRDLLQYIACFFAFFSAGFLIVATWTDCWMVNADDSLEVSTKCRGLWWEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 CCHPDGLLATMRDLLQYIACFFAFFSAGFLIVATWTDCWMVNADDSLEVSTKCRGLWWEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 VTNAFDGIRTCDEYDSILAEHPLKLVVTRALMITADILAGFGFLTLLLGLDCVKFLPDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 VTNAFDGIRTCDEYDSILAEHPLKLVVTRALMITADILAGFGFLTLLLGLDCVKFLPDEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 YIKVRICFVAGATLLIAGTPGIIGSVWYAVDVYVERSTLVLHNIFLGIQYKFGWSCWLGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 YIKVRICFVAGATLLIAGTPGIIGSVWYAVDVYVERSTLVLHNIFLGIQYKFGWSCWLGM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 AGSLGCFLAGAVLTCCLYLFKDVGPERNYPYSLRKAYSAAGVSMAKSYSAPRTETAKMYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 AGSLGCFLAGAVLTCCLYLFKDVGPERNYPYSLRKAYSAAGVSMAKSYSAPRTETAKMYA
250 260 270 280 290 300
pF1KE4 VDTRV
:::::
CCDS32 VDTRV
>>CCDS11096.1 CLDN7 gene_id:1366|Hs108|chr17 (211 aa)
initn: 280 init1: 126 opt: 292 Z-score: 368.0 bits: 75.6 E(32554): 3.5e-14
Smith-Waterman score: 292; 28.8% identity (62.9% similar) in 205 aa overlap (75-272:6-204)
50 60 70 80 90 100
pF1KE4 KTDTRHLSGARAGVCPCCHPDGLLATMRDLLQYIACFFAFFSAGFLIVATWTDCWMVNA-
:: .. .:... :.. : :....
CCDS11 MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSY
10 20 30
110 120 130 140 150 160
pF1KE4 --DDSLEVSTKCRGLWWECVTNAFDGIRTCDEYDSILAEHPLKLVVTRALMITADILAGF
:. . ... .::: .:::.. :. .: :::.:: : .:::::... .:. .
CCDS11 AGDNIITAQAMYKGLWMDCVTQS-TGMMSCKMYDSVLALSA-ALQATRALMVVSLVLGFL
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE4 GFLTLLLGLDCVKFLPDEPYIKVRICFVAGATLLIAGTPGIIGSVWYAVDVYVE-RSTLV
.... .:. :.. :. :.:: . .: ...:: .... ::. .. .. . :.
CCDS11 AMFVATMGMKCTRCGGDDKVKKARIAMGGGIIFIVAGLAALVACSWYGHQIVTDFYNPLI
100 110 120 130 140 150
230 240 250 260 270
pF1KE4 LHNIFLGIQYKFGWSCWLGMAGSLGCFLAGAVLTC-CLYLFKDVGPE--RNYPYSLRKAY
:: .:.:: . ..: ::: .:.::.:.: : . .: . :.:: :
CCDS11 PTNI----KYEFGPAIFIGWAGSALVILGGALLSCSCPGNESKAGYRVPRSYPKSNSSKE
160 170 180 190 200
280 290 300
pF1KE4 SAAGVSMAKSYSAPRTETAKMYAVDTRV
CCDS11 YV
210
>>CCDS3295.1 CLDN1 gene_id:9076|Hs108|chr3 (211 aa)
initn: 208 init1: 146 opt: 280 Z-score: 353.1 bits: 72.9 E(32554): 2.4e-13
Smith-Waterman score: 281; 27.4% identity (58.4% similar) in 219 aa overlap (74-288:8-210)
50 60 70 80 90 100
pF1KE4 QKTDTRHLSGARAGVCPCCHPDGLLATMRDLLQYIACFFAFFSAGFLIVATWTDCWMVNA
:: .: :.....: ::.: : . .
CCDS32 MANAGLQLLGFILAFLGWIGA---IVSTALPQWRIYS
10 20 30
110 120 130 140 150 160
pF1KE4 ---DDSLEVSTKCRGLWWECVTNAFDGIRTCDEYDSILAEHPLKLVVTRALMITADILAG
:. . ... .::: ::... :. : .::.: : .:::::... .:.
CCDS32 YAGDNIVTAQAMYEGLWMSCVSQSTGQIQ-CKVFDSLLNLSST-LQATRALMVVGILLGV
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE4 FGFLTLLLGLDCVKFLPDEPYIKVRICFVAGATLLIAGTPGIIGSVWYAVDVYVERSTLV
..... .:. :.: : :. :.:. ..:: .:.:: .....::. . : .
CCDS32 IAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAIFLLAGLAILVATAWYGNRIVQEFYDPM
100 110 120 130 140 150
230 240 250 260 270
pF1KE4 LHNIFLGIQYKFGWSCWLGMAGSLGCFLAGAVLTC-CLYLFKDVGPERNYPYSLRKAYSA
.. .:.:: . . : :.. :.:.::.: : : :... : . :
CCDS32 TP---VNARYEFGQALFTGWAAASLCLLGGALLCCSC--------PRKTTSYPTPRPYPK
160 170 180 190 200
280 290 300
pF1KE4 AGVSMAKSYSAPRTETAKMYAVDTRV
. : .:.:
CCDS32 PAPSSGKDYV
210
>>CCDS5717.1 CLDN15 gene_id:24146|Hs108|chr7 (228 aa)
initn: 171 init1: 133 opt: 259 Z-score: 326.6 bits: 68.1 E(32554): 7.2e-12
Smith-Waterman score: 259; 30.9% identity (59.9% similar) in 207 aa overlap (82-279:8-201)
60 70 80 90 100
pF1KE4 SGARAGVCPCCHPDGLLATMRDLLQYIACFFAFFSA--GFLI--VATWTDCWMVNA--DD
:.:: : :.:. :. .. : :.. .
CCDS57 MSMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGN
10 20 30
110 120 130 140 150 160
pF1KE4 SLEVSTKCRGLWWECVTNAFDGIRTCDEYDSILAEHPLKLVVTRALMITADILAGF-GFL
. ..: ..::. :.:... :. .: :. :.:: . . ::::::: :: :: :.:
CCDS57 VITTNTIFENLWFSCATDSL-GVYNCWEFPSMLALSGY-IQACRALMITA-ILLGFLGLL
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE4 TLLLGLDCVKFLPDEPYIKVRICFVAGATLLIAGTPGIIGSVWYAVDVYVERSTLVLHNI
. :: :... : :... .::: ..:: :... ::: .. . . .
CCDS57 LGIAGLRCTNIGGLELSRKAKLAATAGALHILAGICGMVAISWYAFNI----TRDFFDPL
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE4 FLGIQYKFGWSCWLGMAGSLGCFLAGAVL--TCCLYLFKDVGPERNYPYSLRKAYSAAGV
. : .:..: . .:: ..:: .:.: : .:: : ... : :. :.:
CCDS57 YPGTKYELGPALYLGWSASLISILGGLCLCSACC------CGSDEDPAASARRPYQAPVS
160 170 180 190 200
290 300
pF1KE4 SMAKSYSAPRTETAKMYAVDTRV
CCDS57 VMPVATSDQEGDSSFGKYGRNAYV
210 220
305 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:28:37 2016 done: Sat Nov 5 23:28:38 2016
Total Scan time: 2.440 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]