Result of FASTA (omim) for
pFN21AE4288
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4288, 1683 aa
1>>>pF1KE4288 1683 - 1683 aa - 1683 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6967+/-0.000495; mu= 18.1091+/- 0.031
mean_var=133.9362+/-27.538, 0's: 0 Z-trim(111.8): 249 B-trim: 55 in 1/53
Lambda= 0.110822
statistics sampled from 20174 (20474) to 20174 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.586), E-opt: 0.2 (0.24), width: 16
Scan time: 10.560
The best scores are: opt bits E(85289)
XP_006715504 (OMIM: 608048) PREDICTED: E3 ubiquiti (1683) 11280 1816.9 0
NP_001036148 (OMIM: 608048) E3 ubiquitin-protein l (1683) 11280 1816.9 0
XP_011534021 (OMIM: 608048) PREDICTED: E3 ubiquiti (1677) 11105 1789.0 0
XP_016866182 (OMIM: 608048) PREDICTED: E3 ubiquiti (1690) 11094 1787.2 0
XP_016866180 (OMIM: 608048) PREDICTED: E3 ubiquiti (1744) 11094 1787.2 0
XP_016866181 (OMIM: 608048) PREDICTED: E3 ubiquiti (1744) 11094 1787.2 0
XP_006715502 (OMIM: 608048) PREDICTED: E3 ubiquiti (1707) 11092 1786.9 0
XP_006715506 (OMIM: 608048) PREDICTED: E3 ubiquiti (1507) 10172 1639.8 0
NP_775105 (OMIM: 608048) E3 ubiquitin-protein liga (1659) 9785 1577.9 0
XP_016866183 (OMIM: 608048) PREDICTED: E3 ubiquiti (1430) 9010 1454.0 0
XP_016866184 (OMIM: 608048) PREDICTED: E3 ubiquiti (1263) 7824 1264.3 0
XP_016866185 (OMIM: 608048) PREDICTED: E3 ubiquiti (1263) 7824 1264.3 0
XP_011534024 (OMIM: 608048) PREDICTED: E3 ubiquiti ( 855) 5601 908.7 0
XP_005271334 (OMIM: 604718) PREDICTED: transcripti (1161) 352 69.6 1.8e-10
XP_016858044 (OMIM: 604718) PREDICTED: transcripti (1162) 352 69.6 1.8e-10
NP_003585 (OMIM: 604718) transcription termination (1162) 352 69.6 1.8e-10
XP_011540605 (OMIM: 604718) PREDICTED: transcripti (1169) 352 69.6 1.9e-10
NP_001305863 (OMIM: 603257) helicase-like transcri (1008) 282 58.4 3.9e-07
XP_016862568 (OMIM: 603257) PREDICTED: helicase-li (1008) 282 58.4 3.9e-07
NP_003062 (OMIM: 603257) helicase-like transcripti (1009) 282 58.4 3.9e-07
NP_001305864 (OMIM: 603257) helicase-like transcri (1009) 282 58.4 3.9e-07
NP_620636 (OMIM: 603257) helicase-like transcripti (1009) 282 58.4 3.9e-07
XP_016862567 (OMIM: 603257) PREDICTED: helicase-li (1012) 282 58.4 3.9e-07
XP_011511395 (OMIM: 603257) PREDICTED: helicase-li (1012) 282 58.4 3.9e-07
XP_011511394 (OMIM: 603257) PREDICTED: helicase-li (1013) 282 58.4 3.9e-07
XP_011511393 (OMIM: 603257) PREDICTED: helicase-li (1013) 282 58.4 3.9e-07
NP_060139 (OMIM: 300687) DNA excision repair prote (1250) 261 55.1 4.7e-06
NP_001276004 (OMIM: 603946,616911) lymphoid-specif ( 432) 241 51.5 1.9e-05
NP_001276003 (OMIM: 603946,616911) lymphoid-specif ( 477) 241 51.5 2.1e-05
XP_016872370 (OMIM: 605191) PREDICTED: TATA-bindin (1519) 247 52.9 2.5e-05
XP_016872369 (OMIM: 605191) PREDICTED: TATA-bindin (1519) 247 52.9 2.5e-05
XP_016872368 (OMIM: 605191) PREDICTED: TATA-bindin (1519) 247 52.9 2.5e-05
XP_016872367 (OMIM: 605191) PREDICTED: TATA-bindin (1646) 247 53.0 2.7e-05
XP_011538630 (OMIM: 605191) PREDICTED: TATA-bindin (1693) 247 53.0 2.8e-05
NP_001276002 (OMIM: 603946,616911) lymphoid-specif ( 700) 241 51.7 2.8e-05
XP_011538629 (OMIM: 605191) PREDICTED: TATA-bindin (1725) 247 53.0 2.8e-05
NP_001276001 (OMIM: 603946,616911) lymphoid-specif ( 708) 241 51.7 2.8e-05
NP_001276000 (OMIM: 603946,616911) lymphoid-specif ( 714) 241 51.7 2.8e-05
XP_016872366 (OMIM: 605191) PREDICTED: TATA-bindin (1800) 247 53.0 2.9e-05
XP_011538628 (OMIM: 605191) PREDICTED: TATA-bindin (1812) 247 53.0 2.9e-05
NP_001275999 (OMIM: 603946,616911) lymphoid-specif ( 740) 241 51.7 2.9e-05
NP_003963 (OMIM: 605191) TATA-binding protein-asso (1849) 247 53.0 2.9e-05
NP_001275998 (OMIM: 603946,616911) lymphoid-specif ( 806) 241 51.7 3.1e-05
NP_001275997 (OMIM: 603946,616911) lymphoid-specif ( 822) 241 51.7 3.1e-05
NP_060533 (OMIM: 603946,616911) lymphoid-specific ( 838) 241 51.7 3.2e-05
NP_001275996 (OMIM: 603946,616911) lymphoid-specif ( 884) 241 51.8 3.3e-05
NP_056372 (OMIM: 610771) chromodomain-helicase-DNA (1954) 239 51.7 7.4e-05
XP_016860560 (OMIM: 615655) PREDICTED: DNA anneali (1038) 224 49.1 0.00025
XP_011510268 (OMIM: 615655) PREDICTED: DNA anneali (1038) 224 49.1 0.00025
NP_001273497 (OMIM: 615655) DNA annealing helicase (1077) 224 49.1 0.00025
>>XP_006715504 (OMIM: 608048) PREDICTED: E3 ubiquitin-pr (1683 aa)
initn: 11280 init1: 11280 opt: 11280 Z-score: 9749.3 bits: 1816.9 E(85289): 0
Smith-Waterman score: 11280; 100.0% identity (100.0% similar) in 1683 aa overlap (1-1683:1-1683)
10 20 30 40 50 60
pF1KE4 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE4 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE4 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE4 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE4 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE4 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE4 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE4 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE4 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE4 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE4 DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE4 VKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHR
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE4 IGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFTKETE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFTKETE
1630 1640 1650 1660 1670 1680
pF1KE4 ELE
:::
XP_006 ELE
>>NP_001036148 (OMIM: 608048) E3 ubiquitin-protein ligas (1683 aa)
initn: 11280 init1: 11280 opt: 11280 Z-score: 9749.3 bits: 1816.9 E(85289): 0
Smith-Waterman score: 11280; 100.0% identity (100.0% similar) in 1683 aa overlap (1-1683:1-1683)
10 20 30 40 50 60
pF1KE4 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE4 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE4 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE4 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE4 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE4 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE4 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE4 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE4 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE4 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE4 DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE4 VKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHR
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE4 IGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFTKETE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFTKETE
1630 1640 1650 1660 1670 1680
pF1KE4 ELE
:::
NP_001 ELE
>>XP_011534021 (OMIM: 608048) PREDICTED: E3 ubiquitin-pr (1677 aa)
initn: 11275 init1: 11105 opt: 11105 Z-score: 9598.1 bits: 1789.0 E(85289): 0
Smith-Waterman score: 11105; 99.9% identity (99.9% similar) in 1655 aa overlap (1-1655:1-1655)
10 20 30 40 50 60
pF1KE4 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE4 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE4 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE4 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE4 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE4 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE4 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE4 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE4 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE4 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE4 DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE4 VKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHR
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE4 IGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFTKETE
:::::::::::::::::::::::::::::::: .:
XP_011 IGQTKPTIVHRFLIKATIEERMQAMLKTAERSSSNVLKLFTFIKRRDNLSKMQRSPC
1630 1640 1650 1660 1670
pF1KE4 ELE
>>XP_016866182 (OMIM: 608048) PREDICTED: E3 ubiquitin-pr (1690 aa)
initn: 11263 init1: 11093 opt: 11094 Z-score: 9588.5 bits: 1787.2 E(85289): 0
Smith-Waterman score: 11094; 99.5% identity (99.8% similar) in 1660 aa overlap (1-1660:1-1660)
10 20 30 40 50 60
pF1KE4 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE4 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE4 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE4 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE4 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE4 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE4 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE4 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE4 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE4 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE4 DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE4 VKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHR
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE4 IGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFTKETE
::::::::::::::::::::::::::::::: . ... :
XP_016 IGQTKPTIVHRFLIKATIEERMQAMLKTAERRYWKKQFIHHHYIKRTLIRPSIPNWSQWT
1630 1640 1650 1660 1670 1680
pF1KE4 ELE
XP_016 YERKKGPQVF
1690
>>XP_016866180 (OMIM: 608048) PREDICTED: E3 ubiquitin-pr (1744 aa)
initn: 11263 init1: 11093 opt: 11094 Z-score: 9588.3 bits: 1787.2 E(85289): 0
Smith-Waterman score: 11094; 99.5% identity (99.8% similar) in 1660 aa overlap (1-1660:1-1660)
10 20 30 40 50 60
pF1KE4 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE4 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE4 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE4 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE4 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE4 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE4 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE4 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE4 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE4 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE4 DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE4 VKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHR
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE4 IGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFTKETE
::::::::::::::::::::::::::::::: . ... :
XP_016 IGQTKPTIVHRFLIKATIEERMQAMLKTAERRYWKKQFIHHHYIKRTLIRPSIPNWSQWT
1630 1640 1650 1660 1670 1680
pF1KE4 ELE
XP_016 YERKKGPQVSFKGQTPKMCTFQQLPRDRVSYCQILKGIQGLKGPIAIDHQFPSVVLRDLQ
1690 1700 1710 1720 1730 1740
>>XP_016866181 (OMIM: 608048) PREDICTED: E3 ubiquitin-pr (1744 aa)
initn: 11263 init1: 11093 opt: 11094 Z-score: 9588.3 bits: 1787.2 E(85289): 0
Smith-Waterman score: 11094; 99.5% identity (99.8% similar) in 1660 aa overlap (1-1660:1-1660)
10 20 30 40 50 60
pF1KE4 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE4 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE4 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE4 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE4 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE4 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE4 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE4 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE4 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE4 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE4 DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE4 VKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHR
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE4 IGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFTKETE
::::::::::::::::::::::::::::::: . ... :
XP_016 IGQTKPTIVHRFLIKATIEERMQAMLKTAERRYWKKQFIHHHYIKRTLIRPSIPNWSQWT
1630 1640 1650 1660 1670 1680
pF1KE4 ELE
XP_016 YERKKGPQVSFKGQTPKMCTFQQLPRDRVSYCQILKGIQGLKGPIAIDHQFPSVVLRDLQ
1690 1700 1710 1720 1730 1740
>>XP_006715502 (OMIM: 608048) PREDICTED: E3 ubiquitin-pr (1707 aa)
initn: 11092 init1: 11092 opt: 11092 Z-score: 9586.7 bits: 1786.9 E(85289): 0
Smith-Waterman score: 11092; 100.0% identity (100.0% similar) in 1651 aa overlap (1-1651:1-1651)
10 20 30 40 50 60
pF1KE4 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE4 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE4 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE4 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE4 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE4 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE4 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE4 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE4 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE4 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE4 DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE4 VKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHR
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE4 IGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFTKETE
:::::::::::::::::::::::::::::::
XP_006 IGQTKPTIVHRFLIKATIEERMQAMLKTAERRFFEEQALFCFHDITPFSHPWSLTTAILQ
1630 1640 1650 1660 1670 1680
pF1KE4 ELE
XP_006 LRDLVICFLGPQHKPDTHMMQITYVDK
1690 1700
>>XP_006715506 (OMIM: 608048) PREDICTED: E3 ubiquitin-pr (1507 aa)
initn: 10172 init1: 10172 opt: 10172 Z-score: 8792.5 bits: 1639.8 E(85289): 0
Smith-Waterman score: 10172; 100.0% identity (100.0% similar) in 1505 aa overlap (1-1505:1-1505)
10 20 30 40 50 60
pF1KE4 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE4 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAH
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE4 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE4 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE4 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEEL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE4 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE4 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE4 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHII
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE4 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLG
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE4 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEE
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE4 DIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISR
:::::
XP_006 DIPVKVF
>>NP_775105 (OMIM: 608048) E3 ubiquitin-protein ligase S (1659 aa)
initn: 9833 init1: 6788 opt: 9785 Z-score: 8457.5 bits: 1577.9 E(85289): 0
Smith-Waterman score: 11006; 99.2% identity (99.2% similar) in 1661 aa overlap (1-1652:1-1656)
10 20 30 40 50 60
pF1KE4 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQKKEPMSICDKGILVESS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 FSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 IPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 NSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 SLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 SGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 YVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 INRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKIL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 WRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLS
910 920 930 940 950 960
970 980 990 1000 1010
pF1KE4 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKS---------TMTMEELLTSLQKK
::::::::::::::::::::::::::::::::::::: ::::::::::::::
NP_775 SLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSFEQSTFSFSTMTMEELLTSLQKK
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE4 CGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHA
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE4 THNLMELLIARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 THNLMELLIARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHEL
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KE4 QRKIHSNSPWWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQF
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_775 QRKIHSNSPWWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEK-----GLQF
1150 1160 1170 1180 1190
1200 1210 1220 1230 1240 1250
pF1KE4 LLTTQMEELNKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LLTTQMEELNKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFT
1200 1210 1220 1230 1240 1250
1260 1270 1280 1290 1300 1310
pF1KE4 EYESKLFSNTVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 EYESKLFSNTVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSH
1260 1270 1280 1290 1300 1310
1320 1330 1340 1350 1360 1370
pF1KE4 RFDVEFVDEGSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 RFDVEFVDEGSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPK
1320 1330 1340 1350 1360 1370
1380 1390 1400 1410 1420 1430
pF1KE4 PNPPVLHIIEPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 PNPPVLHIIEPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEP
1380 1390 1400 1410 1420 1430
1440 1450 1460 1470 1480 1490
pF1KE4 CPICARQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 CPICARQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVF
1440 1450 1460 1470 1480 1490
1500 1510 1520 1530 1540 1550
pF1KE4 TSEKANQEEDIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 TSEKANQEEDIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDN
1500 1510 1520 1530 1540 1550
1560 1570 1580 1590 1600 1610
pF1KE4 NMEFAQISRVKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 NMEFAQISRVKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHE
1560 1570 1580 1590 1600 1610
1620 1630 1640 1650 1660 1670
pF1KE4 LQAIGRVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEASVLTVADL
:::::::::::::::::::::::::::::::::::::::::
NP_775 LQAIGRVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERSIYI
1620 1630 1640 1650
1680
pF1KE4 ADLFTKETEELE
>>XP_016866183 (OMIM: 608048) PREDICTED: E3 ubiquitin-pr (1430 aa)
initn: 9179 init1: 9009 opt: 9010 Z-score: 7788.7 bits: 1454.0 E(85289): 0
Smith-Waterman score: 9010; 99.4% identity (99.7% similar) in 1346 aa overlap (315-1660:1-1346)
290 300 310 320 330 340
pF1KE4 QQETQSIQVDVQHPALIPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGL
::::::::::::::::::::::::::::::
XP_016 MLQQECFRSSPATESALHFLWREIVTSEGL
10 20 30
350 360 370 380 390 400
pF1KE4 KLYYNPYTGCIIREYPNSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLYYNPYTGCIIREYPNSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPE
40 50 60 70 80 90
410 420 430 440 450 460
pF1KE4 GKVVNYFIPSHYFGGKLKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKVVNYFIPSHYFGGKLKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSI
100 110 120 130 140 150
470 480 490 500 510 520
pF1KE4 YKYVSSIYRYDVQRNRSLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKYVSSIYRYDVQRNRSLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTK
160 170 180 190 200 210
530 540 550 560 570 580
pF1KE4 KQAVGSPRKIQKETRKSGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQAVGSPRKIQKETRKSGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPST
220 230 240 250 260 270
590 600 610 620 630 640
pF1KE4 KKGKSQPFINPDSQGHCPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGKSQPFINPDSQGHCPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVP
280 290 300 310 320 330
650 660 670 680 690 700
pF1KE4 PSNTMSPFNTSDYRFECICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSNTMSPFNTSDYRFECICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCP
340 350 360 370 380 390
710 720 730 740 750 760
pF1KE4 HCLVAMEPVSTRATLIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCLVAMEPVSTRATLIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAE
400 410 420 430 440 450
770 780 790 800 810 820
pF1KE4 QDIVIITYDVLRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDIVIITYDVLRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMV
460 470 480 490 500 510
830 840 850 860 870 880
pF1KE4 ECPTVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECPTVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPY
520 530 540 550 560 570
890 900 910 920 930 940
pF1KE4 CKKNPQHLYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKKNPQHLYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQD
580 590 600 610 620 630
950 960 970 980 990 1000
pF1KE4 VVVKLRKISDWALKLSSLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVVKLRKISDWALKLSSLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEEL
640 650 660 670 680 690
1010 1020 1030 1040 1050 1060
pF1KE4 LTSLQKKCGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTSLQKKCGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTD
700 710 720 730 740 750
1070 1080 1090 1100 1110 1120
pF1KE4 SLQRLHATHNLMELLIARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLQRLHATHNLMELLIARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPV
760 770 780 790 800 810
1130 1140 1150 1160 1170 1180
pF1KE4 QQTIHELQRKIHSNSPWWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQTIHELQRKIHSNSPWWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFR
820 830 840 850 860 870
1190 1200 1210 1220 1230 1240
pF1KE4 DCRGLQFLLTTQMEELNKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCRGLQFLLTTQMEELNKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFC
880 890 900 910 920 930
1250 1260 1270 1280 1290 1300
pF1KE4 KADELFTEYESKLFSNTVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KADELFTEYESKLFSNTVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAI
940 950 960 970 980 990
1310 1320 1330 1340 1350 1360
pF1KE4 LSFAKSHRFDVEFVDEGSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSFAKSHRFDVEFVDEGSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRV
1000 1010 1020 1030 1040 1050
1370 1380 1390 1400 1410 1420
pF1KE4 RDPREPKPNPPVLHIIEPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDPREPKPNPPVLHIIEPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTS
1060 1070 1080 1090 1100 1110
1430 1440 1450 1460 1470 1480
pF1KE4 GGVNPEPCPICARQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGVNPEPCPICARQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSH
1120 1130 1140 1150 1160 1170
1490 1500 1510 1520 1530 1540
pF1KE4 KEISYVFTSEKANQEEDIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEISYVFTSEKANQEEDIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDII
1180 1190 1200 1210 1220 1230
1550 1560 1570 1580 1590 1600
pF1KE4 SKALTDNNMEFAQISRVKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKALTDNNMEFAQISRVKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEP
1240 1250 1260 1270 1280 1290
1610 1620 1630 1640 1650 1660
pF1KE4 ILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEAS
::::::::::::::::::::::::::::::::::::::::::::::: . ... :
XP_016 ILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERRYWKKQFIHHHYI
1300 1310 1320 1330 1340 1350
1670 1680
pF1KE4 VLTVADLADLFTKETEELE
XP_016 KRTLIRPSIPNWSQWTYERKKGPQVSFKGQTPKMCTFQQLPRDRVSYCQILKGIQGLKGP
1360 1370 1380 1390 1400 1410
1683 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 19:22:51 2016 done: Mon Nov 7 19:22:53 2016
Total Scan time: 10.560 Total Display time: 0.840
Function used was FASTA [36.3.4 Apr, 2011]