Result of FASTA (omim) for
pFN21AE4264
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4264, 1069 aa
1>>>pF1KE4264 1069 - 1069 aa - 1069 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.4121+/-0.000576; mu= -1.5640+/- 0.036
mean_var=411.9122+/-87.616, 0's: 0 Z-trim(116.8): 181 B-trim: 397 in 1/52
Lambda= 0.063193
statistics sampled from 28160 (28347) to 28160 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.332), width: 16
Scan time: 9.560
The best scores are: opt bits E(85289)
XP_016870056 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 6995 653.8 1.5e-186
XP_011516742 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 6995 653.8 1.5e-186
XP_011516743 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 6995 653.8 1.5e-186
XP_016870057 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 6995 653.8 1.5e-186
XP_016870058 (OMIM: 615882) PREDICTED: rab GTPase- (1069) 6995 653.8 1.5e-186
NP_036329 (OMIM: 615882) rab GTPase-activating pro (1069) 6995 653.8 1.5e-186
XP_016870059 (OMIM: 615882) PREDICTED: rab GTPase- ( 900) 5904 554.2 1.2e-156
XP_011516744 (OMIM: 615882) PREDICTED: rab GTPase- ( 900) 5904 554.2 1.2e-156
XP_011516746 (OMIM: 615882) PREDICTED: rab GTPase- ( 682) 4366 413.9 1.6e-114
XP_005245738 (OMIM: 609238) PREDICTED: rab GTPase- (1014) 2817 272.9 6.7e-72
XP_005245737 (OMIM: 609238) PREDICTED: rab GTPase- (1051) 2817 272.9 6.9e-72
XP_011508525 (OMIM: 609238) PREDICTED: rab GTPase- (1051) 2817 272.9 6.9e-72
XP_006711756 (OMIM: 609238) PREDICTED: rab GTPase- ( 985) 2424 237.0 4e-61
XP_016858483 (OMIM: 609238) PREDICTED: rab GTPase- ( 778) 1830 182.8 6.9e-45
NP_055672 (OMIM: 609238) rab GTPase-activating pro ( 815) 1830 182.8 7.1e-45
NP_001230694 (OMIM: 609238) rab GTPase-activating ( 370) 1384 141.7 7.3e-33
XP_016858485 (OMIM: 609238) PREDICTED: rab GTPase- ( 308) 1137 119.1 3.9e-26
XP_016858486 (OMIM: 609238) PREDICTED: rab GTPase- ( 308) 1137 119.1 3.9e-26
NP_001317918 (OMIM: 609238) rab GTPase-activating ( 308) 1137 119.1 3.9e-26
XP_016858487 (OMIM: 609238) PREDICTED: rab GTPase- ( 253) 993 105.9 3.1e-22
NP_001230693 (OMIM: 609238) rab GTPase-activating ( 253) 993 105.9 3.1e-22
XP_016857773 (OMIM: 602942) PREDICTED: ecotropic v ( 777) 904 98.3 1.8e-19
XP_016857770 (OMIM: 602942) PREDICTED: ecotropic v ( 818) 904 98.4 1.8e-19
NP_001295177 (OMIM: 602942) ecotropic viral integr ( 821) 904 98.4 1.8e-19
XP_016857766 (OMIM: 602942) PREDICTED: ecotropic v ( 854) 904 98.4 1.9e-19
XP_016857774 (OMIM: 602942) PREDICTED: ecotropic v ( 741) 899 97.8 2.4e-19
XP_016857772 (OMIM: 602942) PREDICTED: ecotropic v ( 785) 899 97.9 2.5e-19
XP_016857769 (OMIM: 602942) PREDICTED: ecotropic v ( 826) 899 97.9 2.5e-19
XP_016857765 (OMIM: 602942) PREDICTED: ecotropic v ( 859) 899 97.9 2.6e-19
XP_016857760 (OMIM: 602942) PREDICTED: ecotropic v ( 903) 899 97.9 2.7e-19
NP_005656 (OMIM: 602942) ecotropic viral integrati ( 810) 890 97.1 4.4e-19
XP_016857767 (OMIM: 602942) PREDICTED: ecotropic v ( 848) 862 94.5 2.7e-18
XP_016857768 (OMIM: 602942) PREDICTED: ecotropic v ( 841) 858 94.2 3.4e-18
XP_016857771 (OMIM: 602942) PREDICTED: ecotropic v ( 812) 857 94.1 3.6e-18
XP_016857762 (OMIM: 602942) PREDICTED: ecotropic v ( 886) 857 94.1 3.8e-18
XP_016857763 (OMIM: 602942) PREDICTED: ecotropic v ( 886) 857 94.1 3.8e-18
XP_016857764 (OMIM: 602942) PREDICTED: ecotropic v ( 886) 857 94.1 3.8e-18
XP_016857761 (OMIM: 602942) PREDICTED: ecotropic v ( 897) 857 94.1 3.8e-18
XP_016857759 (OMIM: 602942) PREDICTED: ecotropic v ( 927) 857 94.1 3.9e-18
XP_016857758 (OMIM: 602942) PREDICTED: ecotropic v ( 930) 857 94.1 3.9e-18
XP_016857776 (OMIM: 602942) PREDICTED: ecotropic v ( 722) 799 88.7 1.3e-16
XP_016857777 (OMIM: 602942) PREDICTED: ecotropic v ( 722) 799 88.7 1.3e-16
XP_016857775 (OMIM: 602942) PREDICTED: ecotropic v ( 722) 799 88.7 1.3e-16
XP_016876373 (OMIM: 612465,616087) PREDICTED: TBC1 ( 487) 781 86.9 3.1e-16
XP_016876372 (OMIM: 612465,616087) PREDICTED: TBC1 (1017) 781 87.2 5.1e-16
XP_016876371 (OMIM: 612465,616087) PREDICTED: TBC1 (1054) 781 87.3 5.2e-16
XP_005266662 (OMIM: 612465,616087) PREDICTED: TBC1 (1117) 781 87.3 5.4e-16
XP_006719966 (OMIM: 612465,616087) PREDICTED: TBC1 (1140) 781 87.3 5.4e-16
NP_001273588 (OMIM: 612465,616087) TBC1 domain fam (1235) 781 87.3 5.7e-16
XP_011533633 (OMIM: 612465,616087) PREDICTED: TBC1 (1261) 781 87.4 5.8e-16
>>XP_016870056 (OMIM: 615882) PREDICTED: rab GTPase-acti (1069 aa)
initn: 6995 init1: 6995 opt: 6995 Z-score: 3470.1 bits: 653.8 E(85289): 1.5e-186
Smith-Waterman score: 6995; 100.0% identity (100.0% similar) in 1069 aa overlap (1-1069:1-1069)
10 20 30 40 50 60
pF1KE4 MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 QKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 DDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 DMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 PVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILET
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKES
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 PQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 HMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 HMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGAL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 KFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFER
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 ENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 EKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE4 KIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQ
970 980 990 1000 1010 1020
1030 1040 1050 1060
pF1KE4 LVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
1030 1040 1050 1060
>>XP_011516742 (OMIM: 615882) PREDICTED: rab GTPase-acti (1069 aa)
initn: 6995 init1: 6995 opt: 6995 Z-score: 3470.1 bits: 653.8 E(85289): 1.5e-186
Smith-Waterman score: 6995; 100.0% identity (100.0% similar) in 1069 aa overlap (1-1069:1-1069)
10 20 30 40 50 60
pF1KE4 MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 QKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 DDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 DMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 PVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILET
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKES
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 PQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 HMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 HMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGAL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 KFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFER
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 ENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 EKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE4 KIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQ
970 980 990 1000 1010 1020
1030 1040 1050 1060
pF1KE4 LVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
1030 1040 1050 1060
>>XP_011516743 (OMIM: 615882) PREDICTED: rab GTPase-acti (1069 aa)
initn: 6995 init1: 6995 opt: 6995 Z-score: 3470.1 bits: 653.8 E(85289): 1.5e-186
Smith-Waterman score: 6995; 100.0% identity (100.0% similar) in 1069 aa overlap (1-1069:1-1069)
10 20 30 40 50 60
pF1KE4 MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 QKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 DDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 DMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 PVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILET
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKES
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 PQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 HMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 HMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGAL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 KFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFER
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 ENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 EKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE4 KIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQ
970 980 990 1000 1010 1020
1030 1040 1050 1060
pF1KE4 LVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
1030 1040 1050 1060
>>XP_016870057 (OMIM: 615882) PREDICTED: rab GTPase-acti (1069 aa)
initn: 6995 init1: 6995 opt: 6995 Z-score: 3470.1 bits: 653.8 E(85289): 1.5e-186
Smith-Waterman score: 6995; 100.0% identity (100.0% similar) in 1069 aa overlap (1-1069:1-1069)
10 20 30 40 50 60
pF1KE4 MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 QKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 DDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 DMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 PVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILET
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKES
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 PQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 HMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 HMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGAL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 KFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFER
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 ENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 EKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE4 KIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQ
970 980 990 1000 1010 1020
1030 1040 1050 1060
pF1KE4 LVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
1030 1040 1050 1060
>>XP_016870058 (OMIM: 615882) PREDICTED: rab GTPase-acti (1069 aa)
initn: 6995 init1: 6995 opt: 6995 Z-score: 3470.1 bits: 653.8 E(85289): 1.5e-186
Smith-Waterman score: 6995; 100.0% identity (100.0% similar) in 1069 aa overlap (1-1069:1-1069)
10 20 30 40 50 60
pF1KE4 MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 QKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 DDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 DMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 PVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILET
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKES
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 PQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 HMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 HMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGAL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 KFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFER
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 ENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 EKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE4 KIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQ
970 980 990 1000 1010 1020
1030 1040 1050 1060
pF1KE4 LVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
1030 1040 1050 1060
>>NP_036329 (OMIM: 615882) rab GTPase-activating protein (1069 aa)
initn: 6995 init1: 6995 opt: 6995 Z-score: 3470.1 bits: 653.8 E(85289): 1.5e-186
Smith-Waterman score: 6995; 100.0% identity (100.0% similar) in 1069 aa overlap (1-1069:1-1069)
10 20 30 40 50 60
pF1KE4 MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 QKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 DDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 DMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 PVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILET
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKES
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 PQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 HMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 HMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 HMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 HMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGAL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 KFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFER
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE4 ENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE4 EKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE4 KIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQ
970 980 990 1000 1010 1020
1030 1040 1050 1060
pF1KE4 LVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
1030 1040 1050 1060
>>XP_016870059 (OMIM: 615882) PREDICTED: rab GTPase-acti (900 aa)
initn: 5904 init1: 5904 opt: 5904 Z-score: 2933.5 bits: 554.2 E(85289): 1.2e-156
Smith-Waterman score: 5904; 100.0% identity (100.0% similar) in 900 aa overlap (170-1069:1-900)
140 150 160 170 180 190
pF1KE4 ADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQISLDVTLSVPNVSEGIVRLL
::::::::::::::::::::::::::::::
XP_016 MMSILRSQCQISLDVTLSVPNVSEGIVRLL
10 20 30
200 210 220 230 240 250
pF1KE4 DPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVSRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVSRI
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE4 LYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKEDDGKGYFSAVPKDKDRQCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKEDDGKGYFSAVPKDKDRQCF
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE4 KLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGKSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGKSY
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE4 VITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSPNERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSPNERL
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE4 FWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESESERERRKTTASPSVRLPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESESERERRKTTASPSVRLPQS
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE4 GSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILETWGELLSKWHLNLNVRPKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILETWGELLSKWHLNLNVRPKQL
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE4 SSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQDSAITRDINRTFPAHDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQDSAITRDINRTFPAHDY
400 410 420 430 440 450
620 630 640 650 660 670
pF1KE4 FKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYG
460 470 480 490 500 510
680 690 700 710 720 730
pF1KE4 LRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLY
520 530 540 550 560 570
740 750 760 770 780 790
pF1KE4 MVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEENAKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEENAKK
580 590 600 610 620 630
800 810 820 830 840 850
pF1KE4 LMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFERENRRLQEANMRLEQENDDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFERENRRLQEANMRLEQENDDL
640 650 660 670 680 690
860 870 880 890 900 910
pF1KE4 AHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEEEKRRLEEESAQLKEMCRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEEEKRRLEEESAQLKEMCRRE
700 710 720 730 740 750
920 930 940 950 960 970
pF1KE4 LDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIEKIRQKVDDCERCREFFNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIEKIRQKVDDCERCREFFNKE
760 770 780 790 800 810
980 990 1000 1010 1020 1030
pF1KE4 GRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLEHHLGLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLEHHLGLAL
820 830 840 850 860 870
1040 1050 1060
pF1KE4 NEVQAAKKTWFNRTLSSIKTATGVQGKETC
::::::::::::::::::::::::::::::
XP_016 NEVQAAKKTWFNRTLSSIKTATGVQGKETC
880 890 900
>>XP_011516744 (OMIM: 615882) PREDICTED: rab GTPase-acti (900 aa)
initn: 5904 init1: 5904 opt: 5904 Z-score: 2933.5 bits: 554.2 E(85289): 1.2e-156
Smith-Waterman score: 5904; 100.0% identity (100.0% similar) in 900 aa overlap (170-1069:1-900)
140 150 160 170 180 190
pF1KE4 ADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQISLDVTLSVPNVSEGIVRLL
::::::::::::::::::::::::::::::
XP_011 MMSILRSQCQISLDVTLSVPNVSEGIVRLL
10 20 30
200 210 220 230 240 250
pF1KE4 DPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVSRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVSRI
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE4 LYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKEDDGKGYFSAVPKDKDRQCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKEDDGKGYFSAVPKDKDRQCF
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE4 KLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGKSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGKSY
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE4 VITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSPNERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSPNERL
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE4 FWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESESERERRKTTASPSVRLPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESESERERRKTTASPSVRLPQS
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE4 GSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILETWGELLSKWHLNLNVRPKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILETWGELLSKWHLNLNVRPKQL
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE4 SSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQDSAITRDINRTFPAHDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQDSAITRDINRTFPAHDY
400 410 420 430 440 450
620 630 640 650 660 670
pF1KE4 FKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYG
460 470 480 490 500 510
680 690 700 710 720 730
pF1KE4 LRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLY
520 530 540 550 560 570
740 750 760 770 780 790
pF1KE4 MVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEENAKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEENAKK
580 590 600 610 620 630
800 810 820 830 840 850
pF1KE4 LMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFERENRRLQEANMRLEQENDDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFERENRRLQEANMRLEQENDDL
640 650 660 670 680 690
860 870 880 890 900 910
pF1KE4 AHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEEEKRRLEEESAQLKEMCRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEEEKRRLEEESAQLKEMCRRE
700 710 720 730 740 750
920 930 940 950 960 970
pF1KE4 LDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIEKIRQKVDDCERCREFFNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIEKIRQKVDDCERCREFFNKE
760 770 780 790 800 810
980 990 1000 1010 1020 1030
pF1KE4 GRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLEHHLGLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLEHHLGLAL
820 830 840 850 860 870
1040 1050 1060
pF1KE4 NEVQAAKKTWFNRTLSSIKTATGVQGKETC
::::::::::::::::::::::::::::::
XP_011 NEVQAAKKTWFNRTLSSIKTATGVQGKETC
880 890 900
>>XP_011516746 (OMIM: 615882) PREDICTED: rab GTPase-acti (682 aa)
initn: 4362 init1: 4362 opt: 4366 Z-score: 2177.1 bits: 413.9 E(85289): 1.6e-114
Smith-Waterman score: 4366; 97.7% identity (98.5% similar) in 682 aa overlap (1-680:1-682)
10 20 30 40 50 60
pF1KE4 MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 QKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 SLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 DDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 DMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 PVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 SERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILET
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKES
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 PQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLL
610 620 630 640 650 660
670 680 690 700 710
pF1KE4 H--MPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISL
: : ... .:. :.: :
XP_011 HFKMLGKNTTQVMSAKSFEYLL
670 680
>>XP_005245738 (OMIM: 609238) PREDICTED: rab GTPase-acti (1014 aa)
initn: 4372 init1: 2803 opt: 2817 Z-score: 1411.8 bits: 272.9 E(85289): 6.7e-72
Smith-Waterman score: 4365; 65.2% identity (85.4% similar) in 1018 aa overlap (50-1064:9-999)
20 30 40 50 60 70
pF1KE4 LNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQLQKELADVLMDPPMDDQPGE
:::.::.:: :.: . ..: : . .:.
XP_005 MEVRASLQKIVSNGDEQ-LEKAMEEILRDS--EKRPS-
10 20 30
80 90 100 110 120 130
pF1KE4 KELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMSLPVKPGQGDSEASSPFTP-
. :: : :...: : .. .: .:: ..: . :.. . . : .:
XP_005 SLLV---------DCQSSSEISDHS-FGDIPASQTNKPSLQLILDPSNTEISTPRPSSPG
40 50 60 70 80
140 150 160 170 180 190
pF1KE4 -VADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQISLDVTLSVPNVSEGIVR
. .::::.:.::::::: .:..::.:::::: :. ..:. : . ::: :::: :: ::
XP_005 GLPEEDSVLFNKLTYLGCMKVSSPRNEVEALRAMATMKSSSQYPFPVTLYVPNVPEGSVR
90 100 110 120 130 140
200 210 220 230 240 250
pF1KE4 LLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVS
..: ..:.:::..::::.:::.:::::: ::.::::::: ...: :.:::: :::.::::
XP_005 IIDQSSNVEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFSCEIKEAVS
150 160 170 180 190 200
260 270 280 290 300 310
pF1KE4 RILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKEDDGKGYFSAVPKDKDRQ
:::::: :::.::..:. .. :::::.::::::::.::::::: :: ::::.:.
XP_005 RILYSFCTAFKRSSRQVSDVKDSVIPTPDSDVFTFSVSLEVKEDDGKGNFSPVPKDRDKF
210 220 230 240 250 260
320 330 340 350 360 370
pF1KE4 CFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGK
:::.:::.::.:: ::: .:::::::::::.:::::..:.::::::::.:::::: ::.
XP_005 YFKLKQGIEKKVVITVQQLSNKELAIERCFGMLLSPGRNVKNSDMHLLDMESMGKSYDGR
270 280 290 300 310 320
380 390 400 410 420 430
pF1KE4 SYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSPNE
.::::: :::..: : ..:::::::: ..::.:::.:.::: ::::::::: ::: ::
XP_005 AYVITGMWNPNAPVFLALNEETPKDKQVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANE
330 340 350 360 370 380
440 450 460 470 480 490
pF1KE4 RLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESESERERRKTTASPSVRLP
: :: ::... ::.::..::: . . . : :..:::: :. ::..:. : :
XP_005 R-FWYFSRKTFTETFFMRLKQSEGKGHTNAGDAIYEVVSLQRESDKEEPVT--------P
390 400 410 420 430
500 510 520 530 540 550
pF1KE4 QSGSQSSVIPSPPEDDE-EEDNDEPLLSGSGDVSKECAEKILETWGELLSKWHLNLNVRP
::. : :.::: ::..:. : ::.:::::.: :::: .:::::.::: ::..::
XP_005 TSGGG----PMSPQDDEAEEESDNELSSGTGDVSKDCPEKILYSWGELLGKWHSNLGARP
440 450 460 470 480 490
560 570 580 590 600 610
pF1KE4 KQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQDSAITRDINRTFPA
: ::.::..:::::::.::::::::::.:. ....:::::::.: :.:.:::::.:::::
XP_005 KGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYRILITKDSAQESVITRDIHRTFPA
500 510 520 530 540 550
620 630 640 650 660 670
pF1KE4 HDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMF
::::::::::::.::::::::::::::.:::::::::::::::::::::::: ::::::.
XP_005 HDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFCVLVKIMY
560 570 580 590 600 610
680 690 700 710 720 730
pF1KE4 DYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKF
:::::.:...:::::::::::::::::: .:::..:: :..:::::::::::::::::::
XP_005 DYGLRDLYRNNFEDLHCKFYQLERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKF
620 630 640 650 660 670
740 750 760 770 780 790
pF1KE4 PLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEEN
:: :::::::::::::...::.:::.::::::.::: .::::::::::::::::::.:::
XP_005 PLCMVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEEN
680 690 700 710 720 730
800 810 820 830 840 850
pF1KE4 AKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFERENRRLQEANMRLEQEN
:..::: :::.:. ::::::::::.::::.: :::::..:..:::::::::.:::::::
XP_005 ARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQEN
740 750 760 770 780 790
860 870 880 890 900 910
pF1KE4 DDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEEEKRRLEEESAQLKEMC
:::::::::::::::.:::.::.:::.::::::.:::.:...:::::. :::.:::::.
XP_005 DDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVF
800 810 820 830 840 850
920 930 940 950 960 970
pF1KE4 RRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIEKIRQKVDDCERCREFF
:..:.::: ::::...::..::::::::: ::::::.:.: :.: .. :. :..: ..:
XP_005 RKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIF
860 870 880 890 900 910
980 990 1000 1010 1020 1030
pF1KE4 NKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLEHHLG
.::: .: .. .: .::.::..::.:::::::::::::::::::.::::.:::. :
XP_005 SKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRG
920 930 940 950 960 970
1040 1050 1060
pF1KE4 LALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
.::.::::..::..::.:::::::.:
XP_005 ALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
980 990 1000 1010
1069 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:53:51 2016 done: Mon Nov 7 17:53:52 2016
Total Scan time: 9.560 Total Display time: 0.310
Function used was FASTA [36.3.4 Apr, 2011]