Result of FASTA (omim) for
pFN21AE4234
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4234, 854 aa
1>>>pF1KE4234 854 - 854 aa - 854 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9009+/-0.00044; mu= 18.4933+/- 0.028
mean_var=93.3993+/-18.589, 0's: 0 Z-trim(111.5): 22 B-trim: 0 in 0/50
Lambda= 0.132710
statistics sampled from 20040 (20060) to 20040 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.581), E-opt: 0.2 (0.235), width: 16
Scan time: 11.670
The best scores are: opt bits E(85289)
NP_055211 (OMIM: 605485) vacuolar protein sorting- ( 854) 5705 1103.5 0
NP_542198 (OMIM: 605485) vacuolar protein sorting- ( 829) 5018 972.0 0
XP_016867477 (OMIM: 605485) PREDICTED: vacuolar pr ( 469) 3061 597.1 6.1e-170
XP_011541200 (OMIM: 608549,616683) PREDICTED: vacu ( 579) 178 45.2 0.0011
XP_011541201 (OMIM: 608549,616683) PREDICTED: vacu ( 579) 178 45.2 0.0011
NP_001277114 (OMIM: 608549,616683) vacuolar protei ( 931) 178 45.3 0.0015
NP_068375 (OMIM: 608549,616683) vacuolar protein s ( 941) 178 45.3 0.0015
XP_016877936 (OMIM: 608551) PREDICTED: vacuolar pr ( 605) 174 44.4 0.0019
XP_011520146 (OMIM: 608551) PREDICTED: vacuolar pr ( 871) 174 44.6 0.0025
XP_011520145 (OMIM: 608551) PREDICTED: vacuolar pr ( 901) 174 44.6 0.0025
NP_065908 (OMIM: 608551) vacuolar protein sorting- ( 973) 174 44.6 0.0027
>>NP_055211 (OMIM: 605485) vacuolar protein sorting-asso (854 aa)
initn: 5705 init1: 5705 opt: 5705 Z-score: 5904.1 bits: 1103.5 E(85289): 0
Smith-Waterman score: 5705; 100.0% identity (100.0% similar) in 854 aa overlap (1-854:1-854)
10 20 30 40 50 60
pF1KE4 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 ILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE4 LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE4 SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE4 VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE4 KGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSA
790 800 810 820 830 840
850
pF1KE4 KNRGPGSAILEMKK
::::::::::::::
NP_055 KNRGPGSAILEMKK
850
>>NP_542198 (OMIM: 605485) vacuolar protein sorting-asso (829 aa)
initn: 5018 init1: 5018 opt: 5018 Z-score: 5193.4 bits: 972.0 E(85289): 0
Smith-Waterman score: 5476; 97.1% identity (97.1% similar) in 854 aa overlap (1-854:1-829)
10 20 30 40 50 60
pF1KE4 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH
:::::::::::::::::::::: :::::::::::::
NP_542 GTHYGKVYLLDVQGNITQKFDV-------------------------VQVFGLYSGEEFH
70 80 90
130 140 150 160 170 180
pF1KE4 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE4 GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE4 CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCA
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE4 RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE4 DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQK
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE4 ILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 ILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE4 REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE4 QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE4 LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE4 SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH
640 650 660 670 680 690
730 740 750 760 770 780
pF1KE4 VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM
700 710 720 730 740 750
790 800 810 820 830 840
pF1KE4 KGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 KGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSA
760 770 780 790 800 810
850
pF1KE4 KNRGPGSAILEMKK
::::::::::::::
NP_542 KNRGPGSAILEMKK
820
>>XP_016867477 (OMIM: 605485) PREDICTED: vacuolar protei (469 aa)
initn: 3061 init1: 3061 opt: 3061 Z-score: 3171.9 bits: 597.1 E(85289): 6.1e-170
Smith-Waterman score: 3061; 100.0% identity (100.0% similar) in 459 aa overlap (396-854:11-469)
370 380 390 400 410 420
pF1KE4 IDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKN
::::::::::::::::::::::::::::::
XP_016 MGAERGENSRDIGLAYINHLVERGDYDIAARKCQKILGKN
10 20 30 40
430 440 450 460 470 480
pF1KE4 AALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPG
50 60 70 80 90 100
490 500 510 520 530 540
pF1KE4 DLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHK
110 120 130 140 150 160
550 560 570 580 590 600
pF1KE4 HNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRD
170 180 190 200 210 220
610 620 630 640 650 660
pF1KE4 HHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGN
230 240 250 260 270 280
670 680 690 700 710 720
pF1KE4 SRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPIL
290 300 310 320 330 340
730 740 750 760 770 780
pF1KE4 LIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLV
350 360 370 380 390 400
790 800 810 820 830 840
pF1KE4 DEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNRGP
410 420 430 440 450 460
850
pF1KE4 GSAILEMKK
:::::::::
XP_016 GSAILEMKK
>>XP_011541200 (OMIM: 608549,616683) PREDICTED: vacuolar (579 aa)
initn: 89 init1: 58 opt: 178 Z-score: 187.5 bits: 45.2 E(85289): 0.0011
Smith-Waterman score: 213; 21.1% identity (51.7% similar) in 526 aa overlap (369-843:2-503)
340 350 360 370 380 390
pF1KE4 YSEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIG
:..:. .: :. :. .... . .:
XP_011 MLFKKNLFEMAINLAK--SQHLDSDGLAQIF
10 20
400 410 420 430 440 450
pF1KE4 LAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLP--RGDPVL
. : .:: .:..: :... . .:: : . :: . ... .. :: . . .
XP_011 MQYGDHLYSKGNHDGAVQQYIRTIGKLEP--SYVIRKFLDAQRIHNLTAYLQTLHRQSLA
30 40 50 60 70 80
460 470 480 490 500
pF1KE4 KPLIYEMILHEFLE-SDYEGFATLIR-----EWPGDLYNN-SVIVQA-VRDHLKKDSQNK
. ..:. . . .: . .:. : :. . .:. :: .: ..:.
XP_011 NADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENH
90 100 110 120 130 140
510 520 530 540 550 560
pF1KE4 TLLKTLAELYTYD-KNYGNALEIYLTLRHKDVFQLIHKHN--LFSSIKDKIVLLM-----
. . .. : ::: .::. : ... . ..... :. : .. . :.
XP_011 AHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCT
150 160 170 180 190 200
570 580 590 600
pF1KE4 DF-----------------DSEKAVDMLLDN--EDKISIKKVVEELEDRPELQHVYLHKL
:. .::. . .. .: : : .... : : :. . : .:
XP_011 DYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIYDTLLEL
210 220 230 240 250 260
610 620 630 640 650
pF1KE4 FKRD--HHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPL-EKALEICQQRNFVEETVY
.. :.: . .:: :.:: . .:... : . .::: .::...: . ..:
XP_011 RLQNWAHEKDPQVKEK---LHAEA-----ISLLKSGRFCDVFDKALVLCQMHDFQDGVLY
270 280 290 300 310
660 670 680 690 700 710
pF1KE4 LL--SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSI----DKPPFITG
: ... .. .: :. ..: .. : ::: . :::. . : : ....
XP_011 LYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPS-LWEQALSYFARKEEDCKEYVAA
320 330 340 350 360 370
720 730 740 750 760
pF1KE4 LLNNIGTH--VDPILLIHRIKEG--MEIPNLRDSLVKILQDYNLQILLREGCKKILVADS
.:..: .. . :.:... . .. . .:: ::. :: . :: : . ..
XP_011 VLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREET
380 390 400 410 420 430
770 780 790 800 810 820
pF1KE4 LSLLKKMHRTQMKGVLVDEENICESCLSPI-LPSDAAKPFSVVVFHCRHMFHKECLPMPS
. ..... . . . ... : : : . ::: : : : : ::..:. :
XP_011 TRIRQEIQELKASPKIF-QKTKCSICNSALELPS--------VHFLCGHSFHQHCFESYS
440 450 460 470 480
830 840 850
pF1KE4 MNSAAQFCNICSAKNRGPGSAILEMKK
..: : : .::
XP_011 ESDAD--CPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIADYFGRGVFNK
490 500 510 520 530 540
>>XP_011541201 (OMIM: 608549,616683) PREDICTED: vacuolar (579 aa)
initn: 89 init1: 58 opt: 178 Z-score: 187.5 bits: 45.2 E(85289): 0.0011
Smith-Waterman score: 213; 21.1% identity (51.7% similar) in 526 aa overlap (369-843:2-503)
340 350 360 370 380 390
pF1KE4 YSEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIG
:..:. .: :. :. .... . .:
XP_011 MLFKKNLFEMAINLAK--SQHLDSDGLAQIF
10 20
400 410 420 430 440 450
pF1KE4 LAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLP--RGDPVL
. : .:: .:..: :... . .:: : . :: . ... .. :: . . .
XP_011 MQYGDHLYSKGNHDGAVQQYIRTIGKLEP--SYVIRKFLDAQRIHNLTAYLQTLHRQSLA
30 40 50 60 70 80
460 470 480 490 500
pF1KE4 KPLIYEMILHEFLE-SDYEGFATLIR-----EWPGDLYNN-SVIVQA-VRDHLKKDSQNK
. ..:. . . .: . .:. : :. . .:. :: .: ..:.
XP_011 NADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENH
90 100 110 120 130 140
510 520 530 540 550 560
pF1KE4 TLLKTLAELYTYD-KNYGNALEIYLTLRHKDVFQLIHKHN--LFSSIKDKIVLLM-----
. . .. : ::: .::. : ... . ..... :. : .. . :.
XP_011 AHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCT
150 160 170 180 190 200
570 580 590 600
pF1KE4 DF-----------------DSEKAVDMLLDN--EDKISIKKVVEELEDRPELQHVYLHKL
:. .::. . .. .: : : .... : : :. . : .:
XP_011 DYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIYDTLLEL
210 220 230 240 250 260
610 620 630 640 650
pF1KE4 FKRD--HHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPL-EKALEICQQRNFVEETVY
.. :.: . .:: :.:: . .:... : . .::: .::...: . ..:
XP_011 RLQNWAHEKDPQVKEK---LHAEA-----ISLLKSGRFCDVFDKALVLCQMHDFQDGVLY
270 280 290 300 310
660 670 680 690 700 710
pF1KE4 LL--SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSI----DKPPFITG
: ... .. .: :. ..: .. : ::: . :::. . : : ....
XP_011 LYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPS-LWEQALSYFARKEEDCKEYVAA
320 330 340 350 360 370
720 730 740 750 760
pF1KE4 LLNNIGTH--VDPILLIHRIKEG--MEIPNLRDSLVKILQDYNLQILLREGCKKILVADS
.:..: .. . :.:... . .. . .:: ::. :: . :: : . ..
XP_011 VLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREET
380 390 400 410 420 430
770 780 790 800 810 820
pF1KE4 LSLLKKMHRTQMKGVLVDEENICESCLSPI-LPSDAAKPFSVVVFHCRHMFHKECLPMPS
. ..... . . . ... : : : . ::: : : : : ::..:. :
XP_011 TRIRQEIQELKASPKIF-QKTKCSICNSALELPS--------VHFLCGHSFHQHCFESYS
440 450 460 470 480
830 840 850
pF1KE4 MNSAAQFCNICSAKNRGPGSAILEMKK
..: : : .::
XP_011 ESDAD--CPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIADYFGRGVFNK
490 500 510 520 530 540
>>NP_001277114 (OMIM: 608549,616683) vacuolar protein so (931 aa)
initn: 123 init1: 58 opt: 178 Z-score: 184.6 bits: 45.3 E(85289): 0.0015
Smith-Waterman score: 241; 21.4% identity (52.1% similar) in 555 aa overlap (340-843:325-855)
310 320 330 340 350 360
pF1KE4 LSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKERDQDDHIDWL
.: ::. .. : . .:.: . ... :
NP_001 SSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTRDGRVHALQEKDTQTKLEML
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE4 LEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALW
..:. .: :. :. :: .. . .: . : .:: .:..: :... . .::
NP_001 FKKNLFEMAINLAK-SQ-HLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEP--
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE4 EYEVYKFKEIGQLKAISPYLP--RGDPVLKPLIYEMILHEFLE-SDYEGFATLIR-----
: . :: . ... .. :: . . . . ..:. . . .: . .:.
NP_001 SYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSES
420 430 440 450 460 470
490 500 510 520 530
pF1KE4 EWPGDLYNN-SVIVQA-VRDHLKKDSQNKTLLKTLAELYTYD-KNYGNALEIYLTLRHKD
: :. . .:. :: .: ..:.. . .. : ::: .::. : ..
NP_001 EVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQ
480 490 500 510 520 530
540 550 560 570
pF1KE4 VFQLIHKHN--LFSSIKDKIVLLM-----DF-----------------DSEKAVDMLLDN
. . ..... :. : .. . :. :. .::. . .. .:
NP_001 AESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANN
540 550 560 570 580 590
580 590 600 610 620 630
pF1KE4 --EDKISIKKVVEELEDRPELQHVYLHKLFKRD--HHKGQRYHEKQISLYAEYDRPNLLP
: : .... : : :. . : .: .. :.: . .:: :.:: .
NP_001 PRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEK---LHAEA-----IS
600 610 620 630 640
640 650 660 670 680
pF1KE4 FLRDSTHCPL-EKALEICQQRNFVEETVYLL--SRMGNSRSALKMIMEELHDVDKAIEFA
.:... : . .::: .::...: . ..:: ... .. .: :. ..: .. :
NP_001 LLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERH
650 660 670 680 690 700
690 700 710 720 730
pF1KE4 KEQDDGELWEDLILYSI----DKPPFITGLLNNIGTH--VDPILLIHRIKEG--MEIPNL
::: . :::. . : : .....:..: .. . :.:... . .. . .
NP_001 GEQDPS-LWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVI
710 720 730 740 750 760
740 750 760 770 780 790
pF1KE4 RDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPI-
:: ::. :: . :: : . .. . ..... . . . ... : : : .
NP_001 RDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIF-QKTKCSICNSALE
770 780 790 800 810 820
800 810 820 830 840 850
pF1KE4 LPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNRGPGSAILEMKK
::: : : : : ::..:. : ..: : : .::
NP_001 LPS--------VHFLCGHSFHQHCFESYSESDAD--CPTCLPENRKVMDMIRAQEQKRDL
830 840 850 860 870
NP_001 HDQFQHQLKCSNDSFSVIADYFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRG
880 890 900 910 920 930
>>NP_068375 (OMIM: 608549,616683) vacuolar protein sorti (941 aa)
initn: 123 init1: 58 opt: 178 Z-score: 184.5 bits: 45.3 E(85289): 0.0015
Smith-Waterman score: 241; 21.4% identity (52.1% similar) in 555 aa overlap (340-843:335-865)
310 320 330 340 350 360
pF1KE4 LSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKERDQDDHIDWL
.: ::. .. : . .:.: . ... :
NP_068 SSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTRDGRVHALQEKDTQTKLEML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 LEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALW
..:. .: :. :. :: .. . .: . : .:: .:..: :... . .::
NP_068 FKKNLFEMAINLAK-SQ-HLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEP--
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 EYEVYKFKEIGQLKAISPYLP--RGDPVLKPLIYEMILHEFLE-SDYEGFATLIR-----
: . :: . ... .. :: . . . . ..:. . . .: . .:.
NP_068 SYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSES
430 440 450 460 470 480
490 500 510 520 530
pF1KE4 EWPGDLYNN-SVIVQA-VRDHLKKDSQNKTLLKTLAELYTYD-KNYGNALEIYLTLRHKD
: :. . .:. :: .: ..:.. . .. : ::: .::. : ..
NP_068 EVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQ
490 500 510 520 530 540
540 550 560 570
pF1KE4 VFQLIHKHN--LFSSIKDKIVLLM-----DF-----------------DSEKAVDMLLDN
. . ..... :. : .. . :. :. .::. . .. .:
NP_068 AESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANN
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE4 --EDKISIKKVVEELEDRPELQHVYLHKLFKRD--HHKGQRYHEKQISLYAEYDRPNLLP
: : .... : : :. . : .: .. :.: . .:: :.:: .
NP_068 PRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEK---LHAEA-----IS
610 620 630 640 650
640 650 660 670 680
pF1KE4 FLRDSTHCPL-EKALEICQQRNFVEETVYLL--SRMGNSRSALKMIMEELHDVDKAIEFA
.:... : . .::: .::...: . ..:: ... .. .: :. ..: .. :
NP_068 LLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERH
660 670 680 690 700 710
690 700 710 720 730
pF1KE4 KEQDDGELWEDLILYSI----DKPPFITGLLNNIGTH--VDPILLIHRIKEG--MEIPNL
::: . :::. . : : .....:..: .. . :.:... . .. . .
NP_068 GEQDPS-LWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVI
720 730 740 750 760 770
740 750 760 770 780 790
pF1KE4 RDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPI-
:: ::. :: . :: : . .. . ..... . . . ... : : : .
NP_068 RDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIF-QKTKCSICNSALE
780 790 800 810 820 830
800 810 820 830 840 850
pF1KE4 LPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNRGPGSAILEMKK
::: : : : : ::..:. : ..: : : .::
NP_068 LPS--------VHFLCGHSFHQHCFESYSESDAD--CPTCLPENRKVMDMIRAQEQKRDL
840 850 860 870 880
NP_068 HDQFQHQLKCSNDSFSVIADYFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRG
890 900 910 920 930 940
>>XP_016877936 (OMIM: 608551) PREDICTED: vacuolar protei (605 aa)
initn: 70 init1: 70 opt: 174 Z-score: 183.1 bits: 44.4 E(85289): 0.0019
Smith-Waterman score: 197; 19.6% identity (49.1% similar) in 479 aa overlap (390-823:49-511)
360 370 380 390 400 410
pF1KE4 RDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQ
.: :: :: . : . . .:
XP_016 FRYHVQREARDVWRTYLDMNRFDLAKEYCRERPDCLDTVLAREADFCFRQRRYLESARCY
20 30 40 50 60 70
420 430 440 450 460 470
pF1KE4 KILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPL--IYEMILHEFLESDYEGFA
. . . .: . :: : : .:.. .: : ::: .: .: : .
XP_016 AL---TQSYFEEIALKFLEARQEEALAEFLQRKLASLKPAERTQATLLTTWLTELYLSRL
80 90 100 110 120 130
480 490 500 510 520 530
pF1KE4 TLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALE-IYLTLRH
.. : : . : :.. ... :. . : .. ..:.. . .:...
XP_016 GALQGDPEALTLYRETKECFRTFLSSPRHKEWLFASRASIHELLASHGDTEHMVYFAVIM
140 150 160 170 180 190
540 550 560 570 580
pF1KE4 KDVFQLIHKHNLFSSIKDKIVLL---------MDFDS-------EKAVDMLLDNEDKISI
.: ... : . .. ...: . :. .. :: .. ....
XP_016 QDYERVVAYHCQHEAYEEALAVLARHRDPQLFYKFSPILIRHIPRQLVDAWIEMGSRLDA
200 210 220 230 240 250
590 600 610 620 630
pF1KE4 KKVVEELEDRP---ELQHV-----YLHKLFKRDHHKGQRYHEKQISLYAEYDRPN-LLPF
.... : . :.:.: :.. . . : :. .::::. ::. :: .
XP_016 RQLIPALVNYSQGGEVQQVSQAIRYMEFCVNVLGETEQAIHNYLLSLYAR-GRPDSLLAY
260 270 280 290 300 310
640 650 660 670 680
pF1KE4 LRDS------THCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIE
:... .: :. ::..: ... . :.. . . . :. . .. ::: : .
XP_016 LEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVLELYEEAVDLALQV--DVDLAKQ
320 330 340 350 360 370
690 700 710 720 730
pF1KE4 FAK--EQDD---GELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRI----KEGMEI
: :.:. .:: . . ... . . ... :.: :. . . . :
XP_016 CADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASC--PLLKIEDVLPFFPDFVTI
380 390 400 410 420 430
740 750 760 770 780 790
pF1KE4 PNLRDSLVKILQDYN--LQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESC
...... . :. :: .: : :: . .:.. . . ... . . :. .. : .:
XP_016 DHFKEAICSSLKAYNHHIQELQREMEEA--TASAQRIRRDLQELRGRYGTVEPQDKCATC
440 450 460 470 480
800 810 820 830 840 850
pF1KE4 LSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNRGPGSAILEMKK
:.: .:: .: : :::: .::
XP_016 DFPLL----NRPF--YLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQRKLGAAPPPAK
490 500 510 520 530 540
>>XP_011520146 (OMIM: 608551) PREDICTED: vacuolar protei (871 aa)
initn: 99 init1: 70 opt: 174 Z-score: 180.9 bits: 44.6 E(85289): 0.0025
Smith-Waterman score: 197; 19.6% identity (49.1% similar) in 479 aa overlap (390-823:315-777)
360 370 380 390 400 410
pF1KE4 RDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQ
.: :: :: . : . . .:
XP_011 FRYHVQREARDVWRTYLDMNRFDLAKEYCRERPDCLDTVLAREADFCFRQRRYLESARCY
290 300 310 320 330 340
420 430 440 450 460 470
pF1KE4 KILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPL--IYEMILHEFLESDYEGFA
. . . .: . :: : : .:.. .: : ::: .: .: : .
XP_011 AL---TQSYFEEIALKFLEARQEEALAEFLQRKLASLKPAERTQATLLTTWLTELYLSRL
350 360 370 380 390 400
480 490 500 510 520 530
pF1KE4 TLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALE-IYLTLRH
.. : : . : :.. ... :. . : .. ..:.. . .:...
XP_011 GALQGDPEALTLYRETKECFRTFLSSPRHKEWLFASRASIHELLASHGDTEHMVYFAVIM
410 420 430 440 450 460
540 550 560 570 580
pF1KE4 KDVFQLIHKHNLFSSIKDKIVLL---------MDFDS-------EKAVDMLLDNEDKISI
.: ... : . .. ...: . :. .. :: .. ....
XP_011 QDYERVVAYHCQHEAYEEALAVLARHRDPQLFYKFSPILIRHIPRQLVDAWIEMGSRLDA
470 480 490 500 510 520
590 600 610 620 630
pF1KE4 KKVVEELEDRP---ELQHV-----YLHKLFKRDHHKGQRYHEKQISLYAEYDRPN-LLPF
.... : . :.:.: :.. . . : :. .::::. ::. :: .
XP_011 RQLIPALVNYSQGGEVQQVSQAIRYMEFCVNVLGETEQAIHNYLLSLYAR-GRPDSLLAY
530 540 550 560 570 580
640 650 660 670 680
pF1KE4 LRDS------THCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIE
:... .: :. ::..: ... . :.. . . . :. . .. ::: : .
XP_011 LEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVLELYEEAVDLALQV--DVDLAKQ
590 600 610 620 630
690 700 710 720 730
pF1KE4 FAK--EQDD---GELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRI----KEGMEI
: :.:. .:: . . ... . . ... :.: :. . . . :
XP_011 CADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASC--PLLKIEDVLPFFPDFVTI
640 650 660 670 680 690
740 750 760 770 780 790
pF1KE4 PNLRDSLVKILQDYN--LQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESC
...... . :. :: .: : :: . .:.. . . ... . . :. .. : .:
XP_011 DHFKEAICSSLKAYNHHIQELQREMEEA--TASAQRIRRDLQELRGRYGTVEPQDKCATC
700 710 720 730 740 750
800 810 820 830 840 850
pF1KE4 LSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNRGPGSAILEMKK
:.: .:: .: : :::: .::
XP_011 DFPLL----NRPF--YLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQRKLGAAPPPAK
760 770 780 790 800
>>XP_011520145 (OMIM: 608551) PREDICTED: vacuolar protei (901 aa)
initn: 99 init1: 70 opt: 174 Z-score: 180.7 bits: 44.6 E(85289): 0.0025
Smith-Waterman score: 197; 19.6% identity (49.1% similar) in 479 aa overlap (390-823:345-807)
360 370 380 390 400 410
pF1KE4 RDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQ
.: :: :: . : . . .:
XP_011 FRYHVQREARDVWRTYLDMNRFDLAKEYCRERPDCLDTVLAREADFCFRQRRYLESARCY
320 330 340 350 360 370
420 430 440 450 460 470
pF1KE4 KILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPL--IYEMILHEFLESDYEGFA
. . . .: . :: : : .:.. .: : ::: .: .: : .
XP_011 AL---TQSYFEEIALKFLEARQEEALAEFLQRKLASLKPAERTQATLLTTWLTELYLSRL
380 390 400 410 420 430
480 490 500 510 520 530
pF1KE4 TLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALE-IYLTLRH
.. : : . : :.. ... :. . : .. ..:.. . .:...
XP_011 GALQGDPEALTLYRETKECFRTFLSSPRHKEWLFASRASIHELLASHGDTEHMVYFAVIM
440 450 460 470 480 490
540 550 560 570 580
pF1KE4 KDVFQLIHKHNLFSSIKDKIVLL---------MDFDS-------EKAVDMLLDNEDKISI
.: ... : . .. ...: . :. .. :: .. ....
XP_011 QDYERVVAYHCQHEAYEEALAVLARHRDPQLFYKFSPILIRHIPRQLVDAWIEMGSRLDA
500 510 520 530 540 550
590 600 610 620 630
pF1KE4 KKVVEELEDRP---ELQHV-----YLHKLFKRDHHKGQRYHEKQISLYAEYDRPN-LLPF
.... : . :.:.: :.. . . : :. .::::. ::. :: .
XP_011 RQLIPALVNYSQGGEVQQVSQAIRYMEFCVNVLGETEQAIHNYLLSLYAR-GRPDSLLAY
560 570 580 590 600 610
640 650 660 670 680
pF1KE4 LRDS------THCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIE
:... .: :. ::..: ... . :.. . . . :. . .. ::: : .
XP_011 LEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVLELYEEAVDLALQV--DVDLAKQ
620 630 640 650 660
690 700 710 720 730
pF1KE4 FAK--EQDD---GELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRI----KEGMEI
: :.:. .:: . . ... . . ... :.: :. . . . :
XP_011 CADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASC--PLLKIEDVLPFFPDFVTI
670 680 690 700 710 720
740 750 760 770 780 790
pF1KE4 PNLRDSLVKILQDYN--LQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESC
...... . :. :: .: : :: . .:.. . . ... . . :. .. : .:
XP_011 DHFKEAICSSLKAYNHHIQELQREMEEA--TASAQRIRRDLQELRGRYGTVEPQDKCATC
730 740 750 760 770 780
800 810 820 830 840 850
pF1KE4 LSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNRGPGSAILEMKK
:.: .:: .: : :::: .::
XP_011 DFPLL----NRPF--YLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQRKLGAAPPPAK
790 800 810 820 830
854 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:08:42 2016 done: Mon Nov 7 17:08:44 2016
Total Scan time: 11.670 Total Display time: 0.170
Function used was FASTA [36.3.4 Apr, 2011]