Result of FASTA (omim) for
pFN21AE4183
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4183, 655 aa
1>>>pF1KE4183 655 - 655 aa - 655 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9894+/-0.000404; mu= 7.3781+/- 0.025
mean_var=160.9187+/-32.589, 0's: 0 Z-trim(117.2): 204 B-trim: 721 in 2/51
Lambda= 0.101105
statistics sampled from 28754 (29001) to 28754 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.34), width: 16
Scan time: 10.700
The best scores are: opt bits E(85289)
XP_005270908 (OMIM: 605411,607346,616399) PREDICTE ( 655) 4336 644.9 2.6e-184
NP_004971 (OMIM: 605411,607346,616399) potassium v ( 655) 4336 644.9 2.6e-184
XP_006710692 (OMIM: 605411,607346,616399) PREDICTE ( 655) 4336 644.9 2.6e-184
XP_016856733 (OMIM: 605411,607346,616399) PREDICTE ( 655) 4336 644.9 2.6e-184
XP_006710694 (OMIM: 605411,607346,616399) PREDICTE ( 510) 3351 501.2 3.8e-141
NP_751948 (OMIM: 605411,607346,616399) potassium v ( 636) 3248 486.2 1.5e-136
XP_006710693 (OMIM: 605411,607346,616399) PREDICTE ( 636) 3248 486.2 1.5e-136
NP_036413 (OMIM: 605410) potassium voltage-gated c ( 630) 2757 414.6 5.5e-115
NP_004970 (OMIM: 300281) potassium voltage-gated c ( 647) 2487 375.2 4e-103
XP_011542212 (OMIM: 300281) PREDICTED: potassium v ( 647) 2487 375.2 4e-103
XP_006710695 (OMIM: 605411,607346,616399) PREDICTE ( 375) 2480 374.1 5.2e-103
XP_011539728 (OMIM: 605411,607346,616399) PREDICTE ( 387) 2476 373.5 8.1e-103
XP_011539730 (OMIM: 605411,607346,616399) PREDICTE ( 369) 2475 373.3 8.6e-103
XP_011539729 (OMIM: 605411,607346,616399) PREDICTE ( 369) 2475 373.3 8.6e-103
XP_011539727 (OMIM: 605411,607346,616399) PREDICTE ( 407) 2475 373.3 9.3e-103
XP_016856734 (OMIM: 605411,607346,616399) PREDICTE ( 407) 2475 373.3 9.3e-103
XP_011514467 (OMIM: 605410) PREDICTED: potassium v ( 380) 2128 322.7 1.5e-87
XP_016884997 (OMIM: 300281) PREDICTED: potassium v ( 558) 2026 307.9 6.2e-83
XP_016884998 (OMIM: 300281) PREDICTED: potassium v ( 558) 2026 307.9 6.2e-83
XP_016884999 (OMIM: 300281) PREDICTED: potassium v ( 405) 1931 294.0 7.1e-79
NP_002227 (OMIM: 603787) potassium voltage-gated c ( 494) 769 124.6 8.8e-28
NP_004761 (OMIM: 607738) potassium voltage-gated c ( 911) 741 120.6 2.5e-26
XP_011527101 (OMIM: 600397,616056) PREDICTED: pota ( 858) 715 116.8 3.2e-25
XP_006723847 (OMIM: 600397,616056) PREDICTED: pota ( 858) 715 116.8 3.2e-25
NP_004966 (OMIM: 600397,616056) potassium voltage- ( 858) 715 116.8 3.2e-25
NP_002223 (OMIM: 176263) potassium voltage-gated c ( 575) 666 109.6 3.3e-23
NP_005540 (OMIM: 602420) potassium voltage-gated c ( 511) 654 107.8 1e-22
NP_114092 (OMIM: 176268) potassium voltage-gated c ( 456) 652 107.5 1.1e-22
NP_055194 (OMIM: 608164) potassium voltage-gated c ( 500) 647 106.8 2e-22
XP_016869471 (OMIM: 607738) PREDICTED: potassium v ( 666) 642 106.1 4.2e-22
XP_016869470 (OMIM: 607738) PREDICTED: potassium v ( 666) 642 106.1 4.2e-22
NP_000208 (OMIM: 160120,176260) potassium voltage- ( 495) 636 105.2 6.1e-22
NP_065748 (OMIM: 602906) potassium voltage-gated c ( 477) 568 95.2 5.7e-19
XP_011531127 (OMIM: 603888) PREDICTED: potassium v ( 491) 540 91.2 1e-17
NP_002243 (OMIM: 603888) potassium voltage-gated c ( 491) 540 91.2 1e-17
NP_001269357 (OMIM: 603888) potassium voltage-gate ( 491) 540 91.2 1e-17
XP_016859548 (OMIM: 603888) PREDICTED: potassium v ( 491) 540 91.2 1e-17
XP_011539701 (OMIM: 176262,616366) PREDICTED: pota ( 499) 519 88.1 8.4e-17
XP_011539698 (OMIM: 176262,616366) PREDICTED: pota ( 499) 519 88.1 8.4e-17
XP_011539702 (OMIM: 176262,616366) PREDICTED: pota ( 499) 519 88.1 8.4e-17
XP_011539700 (OMIM: 176262,616366) PREDICTED: pota ( 499) 519 88.1 8.4e-17
NP_004965 (OMIM: 176262,616366) potassium voltage- ( 499) 519 88.1 8.4e-17
XP_016856702 (OMIM: 176262,616366) PREDICTED: pota ( 499) 519 88.1 8.4e-17
XP_011539699 (OMIM: 176262,616366) PREDICTED: pota ( 499) 519 88.1 8.4e-17
NP_002224 (OMIM: 176266) potassium voltage-gated c ( 653) 506 86.3 3.9e-16
XP_005253743 (OMIM: 176257) PREDICTED: potassium v ( 529) 504 85.9 4e-16
XP_011519257 (OMIM: 176257) PREDICTED: potassium v ( 529) 504 85.9 4e-16
NP_002226 (OMIM: 176257) potassium voltage-gated c ( 529) 504 85.9 4e-16
XP_016874760 (OMIM: 176257) PREDICTED: potassium v ( 529) 504 85.9 4e-16
XP_016874759 (OMIM: 176257) PREDICTED: potassium v ( 529) 504 85.9 4e-16
>>XP_005270908 (OMIM: 605411,607346,616399) PREDICTED: p (655 aa)
initn: 4336 init1: 4336 opt: 4336 Z-score: 3429.9 bits: 644.9 E(85289): 2.6e-184
Smith-Waterman score: 4336; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655)
10 20 30 40 50 60
pF1KE4 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
550 560 570 580 590 600
610 620 630 640 650
pF1KE4 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL
610 620 630 640 650
>>NP_004971 (OMIM: 605411,607346,616399) potassium volta (655 aa)
initn: 4336 init1: 4336 opt: 4336 Z-score: 3429.9 bits: 644.9 E(85289): 2.6e-184
Smith-Waterman score: 4336; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655)
10 20 30 40 50 60
pF1KE4 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
550 560 570 580 590 600
610 620 630 640 650
pF1KE4 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL
610 620 630 640 650
>>XP_006710692 (OMIM: 605411,607346,616399) PREDICTED: p (655 aa)
initn: 4336 init1: 4336 opt: 4336 Z-score: 3429.9 bits: 644.9 E(85289): 2.6e-184
Smith-Waterman score: 4336; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655)
10 20 30 40 50 60
pF1KE4 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
550 560 570 580 590 600
610 620 630 640 650
pF1KE4 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL
610 620 630 640 650
>>XP_016856733 (OMIM: 605411,607346,616399) PREDICTED: p (655 aa)
initn: 4336 init1: 4336 opt: 4336 Z-score: 3429.9 bits: 644.9 E(85289): 2.6e-184
Smith-Waterman score: 4336; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655)
10 20 30 40 50 60
pF1KE4 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
550 560 570 580 590 600
610 620 630 640 650
pF1KE4 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL
610 620 630 640 650
>>XP_006710694 (OMIM: 605411,607346,616399) PREDICTED: p (510 aa)
initn: 3351 init1: 3351 opt: 3351 Z-score: 2655.0 bits: 501.2 E(85289): 3.8e-141
Smith-Waterman score: 3351; 99.8% identity (100.0% similar) in 507 aa overlap (1-507:1-507)
10 20 30 40 50 60
pF1KE4 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
::::::::::::::::::::::::::.
XP_006 HCLEKTTGLSYLVDDPLLSVRTSTIKSLQP
490 500 510
>>NP_751948 (OMIM: 605411,607346,616399) potassium volta (636 aa)
initn: 3237 init1: 3237 opt: 3248 Z-score: 2572.4 bits: 486.2 E(85289): 1.5e-136
Smith-Waterman score: 4173; 97.1% identity (97.1% similar) in 655 aa overlap (1-655:1-636)
10 20 30 40 50 60
pF1KE4 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
::::::: ::::::::::::::::::::::::::::::::::
NP_751 HCLEKTT-------------------NHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
490 500 510 520
550 560 570 580 590 600
pF1KE4 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
530 540 550 560 570 580
610 620 630 640 650
pF1KE4 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_751 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL
590 600 610 620 630
>>XP_006710693 (OMIM: 605411,607346,616399) PREDICTED: p (636 aa)
initn: 3237 init1: 3237 opt: 3248 Z-score: 2572.4 bits: 486.2 E(85289): 1.5e-136
Smith-Waterman score: 4173; 97.1% identity (97.1% similar) in 655 aa overlap (1-655:1-636)
10 20 30 40 50 60
pF1KE4 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
::::::: ::::::::::::::::::::::::::::::::::
XP_006 HCLEKTT-------------------NHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
490 500 510 520
550 560 570 580 590 600
pF1KE4 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
530 540 550 560 570 580
610 620 630 640 650
pF1KE4 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL
590 600 610 620 630
>>NP_036413 (OMIM: 605410) potassium voltage-gated chann (630 aa)
initn: 2635 init1: 1482 opt: 2757 Z-score: 2185.4 bits: 414.6 E(85289): 5.5e-115
Smith-Waterman score: 3189; 73.8% identity (87.1% similar) in 660 aa overlap (1-655:1-630)
10 20 30 40 50
pF1KE4 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKR-QDELIVLNVSGRRFQTWRTTLE
:::::::::::::::::::::::. ::: : .. :: :: :::::::: :::::. :::
NP_036 MAAGVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 RYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELA
:::::::::.:..::.. .:..:::::::..:: .:::::::::::::.:::::::.:::
NP_036 RYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 FYGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQES-MPSLSFRQTMWRAFENPHT
:.:..:::::::::::::::.:::::::.:: :... :: .:... :: .:::::::::
NP_036 FFGLIPEIIGDCCYEEYKDRRRENAERLQDDADTDTAGESALPTMTARQRVWRAFENPHT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 STLALVFYYVTGFFIAVSVITNVVETVPCGTVPGS-KELPCGERYSVAFFCLDTACVMIF
::.:::::::::::::::::.:::::::::. :: :::::::::.::::::::::::::
NP_036 STMALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIF
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 TVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRI
:::::::: ::::::::.::::::::::::.:::::::::.:::::::::::::::::::
NP_036 TVEYLLRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMTDNEDVSGAFVTLRVFRVFRI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_036 FKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPAA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRAD
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE4 KRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHH
::::::::::::::.::.::.:::..:::::::.. :. .. :. ..:. : .:.:::
NP_036 KRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQ-SSEDEQAFVSKSGSSFETQHH
430 440 450 460 470
480 490 500 510 520 530
pF1KE4 HLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLS
:::::::::: ::::.:::.::..::: . : ::..:::::
NP_036 HLLHCLEKTT-------------------NHEFVDEQVFEESCMEVATVNRPSSHSPSLS
480 490 500 510 520
540 550 560 570 580 590
pF1KE4 SHPGLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKA
:. :.:.:::::: ::: ..::.:. ... :.::::::.:. :. :..:::::: :
NP_036 SQQGVTSTCCSRRHKKTFRIPNANVSGSHQGSIQELSTIQIRCVERTPLSNSRSSLNAKM
530 540 550 560 570 580
600 610 620 630 640 650
pF1KE4 DDGLRPNCKTSQITTAIISIPTPPALTPEGESRP--PPASPGPNTNIPSIASNVVKVSAL
.. .. ::. .:::::::::::. ::::..:: : : : :.:.::::
NP_036 EECVKLNCEQPYVTTAIISIPTPPVTTPEGDDRPESPEYSGG----------NIVRVSAL
590 600 610 620 630
>>NP_004970 (OMIM: 300281) potassium voltage-gated chann (647 aa)
initn: 2673 init1: 1335 opt: 2487 Z-score: 1972.4 bits: 375.2 E(85289): 4e-103
Smith-Waterman score: 2711; 63.9% identity (81.4% similar) in 678 aa overlap (1-655:1-647)
10 20 30 40 50 60
pF1KE4 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
::::.:.:::::::::.::.:.:. :.: ::. : .: ::..:.:::::::.::..::.:
NP_004 MAAGLATWLPFARAAAVGWLPLAQQPLPPAPGVKASRGDEVLVVNVSGRRFETWKNTLDR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
::::::::.:::::.. :. ::::::::..:: ::::::::.:: :: :::.:.:.::::
NP_004 YPDTLLGSSEKEFFYDADSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAF
70 80 90 100 110 120
130 140 150 160 170
pF1KE4 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSL----SFRQTMWRAFENP
::..::..:::: :::.:::.:::::: .:...:. .. :.: :.:: .:::::::
NP_004 YGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGDG-PALPAGSSLRQRLWRAFENP
130 140 150 160 170
180 190 200 210 220 230
pF1KE4 HTSTLALVFYYVTGFFIAVSVITNVVETVPC-GTVP-GSKELPCGERYSVAFFCLDTACV
:::: :::::::::::::::::.:::::.:: :.. .:.: :::::. ::::.:::::
NP_004 HTSTAALVFYYVTGFFIAVSVIANVVETIPCRGSARRSSREQPCGERFPQAFFCMDTACV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 MIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRV
.::: :::::::::::: ::.:::::.::::::.::::::.. .:.::::::::::::::
NP_004 LIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLLVPKNDDVSGAFVTLRVFRV
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 FRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSI
:::::::::::::::::::::::::::::::::::::::::::::::::::.. ..::::
NP_004 FRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSI
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE4 PASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQ
::.::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
NP_004 PAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQ
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE4 RADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMG-KTTSLIE
::::::::.:.::::::.::.:..::.:. :.:: .:: .:. ::. . .. : .:
NP_004 RADKRRAQQKVRLARIRLAKSGTTNAFLQYKQNG----GLEDSGSGEEQALCVRNRSAFE
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE4 SQHHHLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRS
.::::::::::::: ::: :: : . : . ..::
NP_004 QQHHHLLHCLEKTT-------------------CHEFTDELTFSEALGAVSPGGR-TSRS
480 490 500 510
540 550 560 570 580
pF1KE4 PSLSSHP----GLTTTCCSRRSKKTT-HLPNSNLPATRLRSMQELSTIHIQGSEQPSLTT
:.::.: .: ..:: ::.:. . .: ::. ..: :::::. . : ..
NP_004 TSVSSQPVGPGSLLSSCCPRRAKRRAIRLANSTASVSR-GSMQELDML--AGLRRSHAPQ
520 530 540 550 560 570
590 600 610 620 630
pF1KE4 SRSSLNLKADDGLRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGP---------N
:::::: : :.: :: . ....:::::::::: ::. ::.: .::: :
NP_004 SRSSLNAKPHDSLDLNCDSRDFVAAIISIPTPPANTPD-ESQP--SSPGGGGRAGSTLRN
580 590 600 610 620
640 650
pF1KE4 TNI--PSIASNVVKVSAL
... : . ..::.:.:
NP_004 SSLGTPCLFPETVKISSL
630 640
>>XP_011542212 (OMIM: 300281) PREDICTED: potassium volta (647 aa)
initn: 2673 init1: 1335 opt: 2487 Z-score: 1972.4 bits: 375.2 E(85289): 4e-103
Smith-Waterman score: 2711; 63.9% identity (81.4% similar) in 678 aa overlap (1-655:1-647)
10 20 30 40 50 60
pF1KE4 MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
::::.:.:::::::::.::.:.:. :.: ::. : .: ::..:.:::::::.::..::.:
XP_011 MAAGLATWLPFARAAAVGWLPLAQQPLPPAPGVKASRGDEVLVVNVSGRRFETWKNTLDR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
::::::::.:::::.. :. ::::::::..:: ::::::::.:: :: :::.:.:.::::
XP_011 YPDTLLGSSEKEFFYDADSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAF
70 80 90 100 110 120
130 140 150 160 170
pF1KE4 YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSL----SFRQTMWRAFENP
::..::..:::: :::.:::.:::::: .:...:. .. :.: :.:: .:::::::
XP_011 YGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGDG-PALPAGSSLRQRLWRAFENP
130 140 150 160 170
180 190 200 210 220 230
pF1KE4 HTSTLALVFYYVTGFFIAVSVITNVVETVPC-GTVP-GSKELPCGERYSVAFFCLDTACV
:::: :::::::::::::::::.:::::.:: :.. .:.: :::::. ::::.:::::
XP_011 HTSTAALVFYYVTGFFIAVSVIANVVETIPCRGSARRSSREQPCGERFPQAFFCMDTACV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 MIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRV
.::: :::::::::::: ::.:::::.::::::.::::::.. .:.::::::::::::::
XP_011 LIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLLVPKNDDVSGAFVTLRVFRV
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 FRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSI
:::::::::::::::::::::::::::::::::::::::::::::::::::.. ..::::
XP_011 FRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSI
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE4 PASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQ
::.::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_011 PAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQ
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE4 RADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMG-KTTSLIE
::::::::.:.::::::.::.:..::.:. :.:: .:: .:. ::. . .. : .:
XP_011 RADKRRAQQKVRLARIRLAKSGTTNAFLQYKQNG----GLEDSGSGEEQALCVRNRSAFE
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE4 SQHHHLLHCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRS
.::::::::::::: ::: :: : . : . ..::
XP_011 QQHHHLLHCLEKTT-------------------CHEFTDELTFSEALGAVSPGGR-TSRS
480 490 500 510
540 550 560 570 580
pF1KE4 PSLSSHP----GLTTTCCSRRSKKTT-HLPNSNLPATRLRSMQELSTIHIQGSEQPSLTT
:.::.: .: ..:: ::.:. . .: ::. ..: :::::. . : ..
XP_011 TSVSSQPVGPGSLLSSCCPRRAKRRAIRLANSTASVSR-GSMQELDML--AGLRRSHAPQ
520 530 540 550 560 570
590 600 610 620 630
pF1KE4 SRSSLNLKADDGLRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGP---------N
:::::: : :.: :: . ....:::::::::: ::. ::.: .::: :
XP_011 SRSSLNAKPHDSLDLNCDSRDFVAAIISIPTPPANTPD-ESQP--SSPGGGGRAGSTLRN
580 590 600 610 620
640 650
pF1KE4 TNI--PSIASNVVKVSAL
... : . ..::.:.:
XP_011 SSLGTPCLFPETVKISSL
630 640
655 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:07:40 2016 done: Sun Nov 6 03:07:42 2016
Total Scan time: 10.700 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]