Result of FASTA (omim) for
pFN21AE4176
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4176, 638 aa
1>>>pF1KE4176 638 - 638 aa - 638 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8445+/-0.000394; mu= 6.7676+/- 0.025
mean_var=321.0725+/-68.131, 0's: 0 Z-trim(122.6): 71 B-trim: 2026 in 1/56
Lambda= 0.071577
statistics sampled from 40968 (41047) to 40968 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.481), width: 16
Scan time: 11.550
The best scores are: opt bits E(85289)
NP_258411 (OMIM: 611041) tripartite motif-containi ( 638) 4439 472.3 2.3e-132
XP_005257844 (OMIM: 611041) PREDICTED: tripartite ( 400) 2700 292.5 1.9e-78
XP_005257845 (OMIM: 611041) PREDICTED: tripartite ( 400) 2700 292.5 1.9e-78
NP_006461 (OMIM: 609505) tripartite motif-containi ( 564) 624 78.3 8.3e-14
NP_036233 (OMIM: 610658) tripartite motif-containi ( 588) 399 55.1 8.4e-07
XP_011541034 (OMIM: 610658) PREDICTED: tripartite ( 621) 399 55.1 8.7e-07
XP_011541031 (OMIM: 610658) PREDICTED: tripartite ( 622) 399 55.1 8.7e-07
XP_016870842 (OMIM: 606556) PREDICTED: tripartite ( 442) 302 44.9 0.00072
NP_150088 (OMIM: 606556) tripartite motif-containi ( 442) 302 44.9 0.00072
NP_055603 (OMIM: 606556) tripartite motif-containi ( 442) 302 44.9 0.00072
XP_016870841 (OMIM: 606556) PREDICTED: tripartite ( 442) 302 44.9 0.00072
XP_005252377 (OMIM: 606556) PREDICTED: tripartite ( 442) 302 44.9 0.00072
NP_005073 (OMIM: 600453) E3 ubiquitin/ISG15 ligase ( 630) 291 44.0 0.002
>>NP_258411 (OMIM: 611041) tripartite motif-containing p (638 aa)
initn: 4439 init1: 4439 opt: 4439 Z-score: 2497.4 bits: 472.3 E(85289): 2.3e-132
Smith-Waterman score: 4439; 99.8% identity (99.8% similar) in 638 aa overlap (1-638:1-638)
10 20 30 40 50 60
pF1KE4 MDGSGPFSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_258 MDGSGPFSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 FPDGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_258 FPDGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PAGEEPVRCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_258 PAGEEPVRCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEES
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LCPRHLWPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMD
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_258 LCPRHLRPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_258 ELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 QGDLRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGCGPGPGPPRELSFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_258 QGDLRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGCGPGPGPPRELSFT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 KSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLESTNLLESEAPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_258 KSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLESTNLLESEAPR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 DYFLKFAYIVDLDSDTADKFLQLFGTKGVKRVLCPINYPLSPTRFTHCEQVLGEGALDRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_258 DYFLKFAYIVDLDSDTADKFLQLFGTKGVKRVLCPINYPLSPTRFTHCEQVLGEGALDRG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE4 TYYWEVEIIEGWVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_258 TYYWEVEIIEGWVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE4 PHPFSPTVGVCLEYADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_258 PHPFSPTVGVCLEYADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSH
550 560 570 580 590 600
610 620 630
pF1KE4 FAGLFTHRLKPAFFLESVDAHLQIGPLKKSCISVLKRR
::::::::::::::::::::::::::::::::::::::
NP_258 FAGLFTHRLKPAFFLESVDAHLQIGPLKKSCISVLKRR
610 620 630
>>XP_005257844 (OMIM: 611041) PREDICTED: tripartite moti (400 aa)
initn: 2700 init1: 2700 opt: 2700 Z-score: 1529.2 bits: 292.5 E(85289): 1.9e-78
Smith-Waterman score: 2700; 100.0% identity (100.0% similar) in 400 aa overlap (239-638:1-400)
210 220 230 240 250 260
pF1KE4 HRGHELVPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVS
::::::::::::::::::::::::::::::
XP_005 MDELGAGIAQSRRTVALIKSAAVAERERVS
10 20 30
270 280 290 300 310 320
pF1KE4 RLFADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLFADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPEAD
40 50 60 70 80 90
330 340 350 360 370 380
pF1KE4 SVSFLQELLALRLALEDGCGPGPGPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVSFLQELLALRLALEDGCGPGPGPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPG
100 110 120 130 140 150
390 400 410 420 430 440
pF1KE4 GNEDGPQKLDSEADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNEDGPQKLDSEADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKG
160 170 180 190 200 210
450 460 470 480 490 500
pF1KE4 VKRVLCPINYPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIEGWVSMGVMAEDFSPQEPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKRVLCPINYPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIEGWVSMGVMAEDFSPQEPY
220 230 240 250 260 270
510 520 530 540 550 560
pF1KE4 DRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVGVCLEYADRALAFYAVRDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVGVCLEYADRALAFYAVRDGK
280 290 300 310 320 330
570 580 590 600 610 620
pF1KE4 MSLLRRLKASRPRRGGIPASPIDPFQSRLDSHFAGLFTHRLKPAFFLESVDAHLQIGPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLLRRLKASRPRRGGIPASPIDPFQSRLDSHFAGLFTHRLKPAFFLESVDAHLQIGPLK
340 350 360 370 380 390
630
pF1KE4 KSCISVLKRR
::::::::::
XP_005 KSCISVLKRR
400
>>XP_005257845 (OMIM: 611041) PREDICTED: tripartite moti (400 aa)
initn: 2700 init1: 2700 opt: 2700 Z-score: 1529.2 bits: 292.5 E(85289): 1.9e-78
Smith-Waterman score: 2700; 100.0% identity (100.0% similar) in 400 aa overlap (239-638:1-400)
210 220 230 240 250 260
pF1KE4 HRGHELVPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVS
::::::::::::::::::::::::::::::
XP_005 MDELGAGIAQSRRTVALIKSAAVAERERVS
10 20 30
270 280 290 300 310 320
pF1KE4 RLFADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLFADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPEAD
40 50 60 70 80 90
330 340 350 360 370 380
pF1KE4 SVSFLQELLALRLALEDGCGPGPGPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVSFLQELLALRLALEDGCGPGPGPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPG
100 110 120 130 140 150
390 400 410 420 430 440
pF1KE4 GNEDGPQKLDSEADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNEDGPQKLDSEADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKG
160 170 180 190 200 210
450 460 470 480 490 500
pF1KE4 VKRVLCPINYPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIEGWVSMGVMAEDFSPQEPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKRVLCPINYPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIEGWVSMGVMAEDFSPQEPY
220 230 240 250 260 270
510 520 530 540 550 560
pF1KE4 DRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVGVCLEYADRALAFYAVRDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVGVCLEYADRALAFYAVRDGK
280 290 300 310 320 330
570 580 590 600 610 620
pF1KE4 MSLLRRLKASRPRRGGIPASPIDPFQSRLDSHFAGLFTHRLKPAFFLESVDAHLQIGPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSLLRRLKASRPRRGGIPASPIDPFQSRLDSHFAGLFTHRLKPAFFLESVDAHLQIGPLK
340 350 360 370 380 390
630
pF1KE4 KSCISVLKRR
::::::::::
XP_005 KSCISVLKRR
400
>>NP_006461 (OMIM: 609505) tripartite motif-containing p (564 aa)
initn: 604 init1: 203 opt: 624 Z-score: 368.9 bits: 78.3 E(85289): 8.3e-14
Smith-Waterman score: 629; 27.9% identity (56.9% similar) in 541 aa overlap (73-580:1-529)
50 60 70 80 90
pF1KE4 SGAGGPGGAARCPLCQEPFPDGLQLRKNHTLSELLQLRQGSGP-GSGPGPAP----ALAP
..:: . : : ... ::: . .:
NP_006 MAELDLMAPGPLPRATAQPPAPLSPDSGSP
10 20 30
100 110 120 130 140
pF1KE4 EPSAPSALP--------------SVPEPSAPCAPEPWPAGE-EPVRCDACPEGAA-LPAA
:.. :: : . : .. : . :::: . : :: : . . . :.
NP_006 SPDSGSASPVEEEDVGSSEKLGRETEEQDSDSAEQGDPAGEGKEVLCDFCLDDTRRVKAV
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE4 LSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHLWPLERYCRAERVCLC
:::.:....: :: ::. . :..: :. :.. . :: : :: .: .. :.:
NP_006 KSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRYCPAHHSPLSAFCCPDQQCIC
100 110 120 130 140 150
210 220 230 240 250
pF1KE4 EACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRM--DELGAGIAQSRRTVALIKSA
. : ::: :: .: :. : .::: . . .: .. .: . . :. . .:.
NP_006 QDCC-QEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVLV---
160 170 180 190 200
260 270 280 290 300 310
pF1KE4 AVAERERVSRL-FADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRS-RLSRA
.:.: . :... :.. ::.. :..:. :.:: : : :....: .. . : :: .. ..
NP_006 SVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANG-IKAHLEYRSAEMEKS
210 220 230 240 250 260
320 330 340 350 360 370
pF1KE4 RQNLSQVPE-ADSVSFLQELLALRLALEDGCGPGPGPPRELSFTKSSQAVRAVRDMLAVA
.:.: .. ...:.::.: .. :: :. ... . ...: : .:
NP_006 KQELERMAAISNTVQFLEEYCKFK-NTEDITFPSV----YVGLKDKLSGIRKVITESTVH
270 280 290 300 310 320
380 390 400 410 420 430
pF1KE4 CVNQWEQLRGPGGNEDGPQKLD--SEADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDS
.. :. . . . .. : ....: : :. : . :. ::..:: . .:
NP_006 LIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEP-STREQFLQYAYDITFDP
330 340 350 360 370
440 450 460 470 480 490
pF1KE4 DTADKFLQLFGTKGVKRVLCPIN--YPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIEGW
::: :.:.: . : . :: :.:: : .:::.. .: ::.::::. .
NP_006 DTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAG
380 390 400 410 420 430
500 510 520 530 540 550
pF1KE4 VSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPH-PFSPTVGVC
. .:. . .. . . .. : : :::::. :..:. .:.:: :: .::
NP_006 TYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFR-RLGVY
440 450 460 470 480 490
560 570 580 590 600
pF1KE4 LEYADRALAFYAVRDGKMSLLRRL--KASRPRRGGIPASPIDPFQSRLDSHFAGLFTHRL
... :.::.:. :.:.... : :.:
NP_006 IDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAPS
500 510 520 530 540 550
610 620 630
pF1KE4 KPAFFLESVDAHLQIGPLKKSCISVLKRR
NP_006 LVGTAP
560
>>NP_036233 (OMIM: 610658) tripartite motif-containing p (588 aa)
initn: 349 init1: 288 opt: 399 Z-score: 243.1 bits: 55.1 E(85289): 8.4e-07
Smith-Waterman score: 399; 28.9% identity (56.0% similar) in 266 aa overlap (122-384:166-427)
100 110 120 130 140 150
pF1KE4 APALAPEPSAPSALPSVPEPSAPCAPEPWPAGEEPVRCDACPEGAALPAALSCLSCLASF
.: : : ::.: : :. ::: : :::
NP_036 RKPTVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCI-GNKQKAVKSCLVCQASF
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE4 CPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHLWPLERYCRAERVCLCEACAAQEHRG
: :: :: .. :.: :.:. :.: .: :: : .: .:.....:.: : :::..
NP_036 CELHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQTCICYLCMFQEHKN
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE4 HELVPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLF
: : .:. .: .:.: : .. .. :. . .. ::: .. :. . . :
NP_036 HSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIKSFTTNEKAILEQNF
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE4 ADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPE-ADSV
: . :. . .: . .:. : . . . . .:. . : . .:. :. .:::
NP_036 RDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHEDKQTREQLHSISDSV
320 330 340 350 360 370
340 350 360 370 380
pF1KE4 SFLQELLALRLALEDGCGPGPGPPRELSFTKSS--QAVRAVRDMLAVACVNQWEQLRGPG
::::. :: . . : : : .. . . :.. .: : .:. . :..
NP_036 LFLQEFGAL---MSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVCMRHVEKMCKAD
380 390 400 410 420 430
390 400 410 420 430 440
pF1KE4 GNEDGPQKLDSEADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKG
NP_036 LSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPKGGVRTSYQPSSPG
440 450 460 470 480 490
>>XP_011541034 (OMIM: 610658) PREDICTED: tripartite moti (621 aa)
initn: 349 init1: 288 opt: 399 Z-score: 242.9 bits: 55.1 E(85289): 8.7e-07
Smith-Waterman score: 399; 28.9% identity (56.0% similar) in 266 aa overlap (122-384:166-427)
100 110 120 130 140 150
pF1KE4 APALAPEPSAPSALPSVPEPSAPCAPEPWPAGEEPVRCDACPEGAALPAALSCLSCLASF
.: : : ::.: : :. ::: : :::
XP_011 RKPTVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCI-GNKQKAVKSCLVCQASF
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE4 CPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHLWPLERYCRAERVCLCEACAAQEHRG
: :: :: .. :.: :.:. :.: .: :: : .: .:.....:.: : :::..
XP_011 CELHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQTCICYLCMFQEHKN
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE4 HELVPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLF
: : .:. .: .:.: : .. .. :. . .. ::: .. :. . . :
XP_011 HSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIKSFTTNEKAILEQNF
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE4 ADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPE-ADSV
: . :. . .: . .:. : . . . . .:. . : . .:. :. .:::
XP_011 RDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHEDKQTREQLHSISDSV
320 330 340 350 360 370
340 350 360 370 380
pF1KE4 SFLQELLALRLALEDGCGPGPGPPRELSFTKSS--QAVRAVRDMLAVACVNQWEQLRGPG
::::. :: . . : : : .. . . :.. .: : .:. . :..
XP_011 LFLQEFGAL---MSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVCMRHVEKMCKAD
380 390 400 410 420 430
390 400 410 420 430 440
pF1KE4 GNEDGPQKLDSEADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKG
XP_011 LSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPKGGVRTSYQPSSPG
440 450 460 470 480 490
>>XP_011541031 (OMIM: 610658) PREDICTED: tripartite moti (622 aa)
initn: 349 init1: 288 opt: 399 Z-score: 242.8 bits: 55.1 E(85289): 8.7e-07
Smith-Waterman score: 399; 28.9% identity (56.0% similar) in 266 aa overlap (122-384:166-427)
100 110 120 130 140 150
pF1KE4 APALAPEPSAPSALPSVPEPSAPCAPEPWPAGEEPVRCDACPEGAALPAALSCLSCLASF
.: : : ::.: : :. ::: : :::
XP_011 RKPTVSIMEPGETRRNSYPRADTGLFSRSKSGSEEVLCDSCI-GNKQKAVKSCLVCQASF
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE4 CPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHLWPLERYCRAERVCLCEACAAQEHRG
: :: :: .. :.: :.:. :.: .: :: : .: .:.....:.: : :::..
XP_011 CELHLKPHLEGAAFRDHQLLEPIRDFEARKCPVHGKTMELFCQTDQTCICYLCMFQEHKN
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE4 HELVPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLF
: : .:. .: .:.: : .. .. :. . .. ::: .. :. . . :
XP_011 HSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIKSFTTNEKAILEQNF
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE4 ADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPE-ADSV
: . :. . .: . .:. : . . . . .:. . : . .:. :. .:::
XP_011 RDLVRDLEKQKEEVRAALEQREQDAVDQVKVIMDALDERAKVLHEDKQTREQLHSISDSV
320 330 340 350 360 370
340 350 360 370 380
pF1KE4 SFLQELLALRLALEDGCGPGPGPPRELSFTKSS--QAVRAVRDMLAVACVNQWEQLRGPG
::::. :: . . : : : .. . . :.. .: : .:. . :..
XP_011 LFLQEFGAL---MSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVCMRHVEKMCKAD
380 390 400 410 420 430
390 400 410 420 430 440
pF1KE4 GNEDGPQKLDSEADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKG
XP_011 LSRNFIERNHMENGGDHRYVNNYTNSFGGEWSAPDTMKRYSMYLTPKGGVRTSYQPSSPG
440 450 460 470 480 490
>>XP_016870842 (OMIM: 606556) PREDICTED: tripartite moti (442 aa)
initn: 141 init1: 72 opt: 302 Z-score: 190.4 bits: 44.9 E(85289): 0.00072
Smith-Waterman score: 302; 27.3% identity (51.4% similar) in 414 aa overlap (182-578:24-420)
160 170 180 190 200
pF1KE4 CPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHLWPL-ERYCRAERVCLCEACAAQ-EH
::.: . : .:: : :.: : . :
XP_016 MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAH
10 20 30 40 50
210 220 230 240 250 260
pF1KE4 RGHEL-VPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVS
::: . . :: .:. : . :. . . .. .:.: . .. .:. : . . ..
XP_016 RGHPVGLALEAAVHVQKLSQ-ECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLK
60 70 80 90 100 110
270 280 290 300 310 320
pF1KE4 RLFADAAAALQGFQTQVLGFIEEGEAAMLG--RSQGD-LRRQEEQRSRLSRARQNLSQVP
:.. :. .. . ::... : : :.: :.: . . :: ..:: :
XP_016 GKFTELRLLLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEP
120 130 140 150 160 170
330 340 350 360 370 380
pF1KE4 EADSVSFLQELLALRLALEDGCGPGP-GPPRELSFTKSSQAVRAVRDMLAVACVNQWEQL
: :. :: : . ... . : : ::: . :.. :. : . .
XP_016 --DPVQRLQAYTATEQEMQQQMSLGELCHPVPLSF----EPVKSFFKGLVEAVESTLQTP
180 190 200 210 220
390 400 410 420 430 440
pF1KE4 RGPGGNEDGPQKLDSEADAEPQDLESTNLLESEAP-RDYFLKFAYIVDLDSDTADKFLQL
.:. .:.. ....: : .: : .: :. .::.: :: :: :.:
XP_016 LDIRLKESINCQLSDPSSTKPGTLLKT----SPSPERSLLLKYARTPTLDPDTMHARLRL
230 240 250 260 270 280
450 460 470 480 490
pF1KE4 FGTKGVKRVLCPINYPLSPT---RFTHCEQVLGEGALDRGTYYWEVEIIE---GWVSMGV
. . . : : . :.:. :: :::.. . : .::::.. : :: .:.
XP_016 SADRLTVR--CGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWW-VGA
290 300 310 320 330
500 510 520 530 540 550
pF1KE4 MAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVW-FH-GLEAPL-PHPFSPTVGVCLEY
.. . .::: : .: ::. .. : :: : .. : :. .:: :.:
XP_016 AYASLRRRGASAAARLGCNRQSWCLKR--YDLEYWAFHDGQRSRLRPRDDLDRLGVFLDY
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE4 ADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSHFAGLFTHRLKPAFF
.:::: : : :: :. ..:.
XP_016 EAGVLAFYDVTGG-MSHLHTFRATFQEPLYPALRLWEGAISIPRLP
400 410 420 430 440
>>NP_150088 (OMIM: 606556) tripartite motif-containing p (442 aa)
initn: 141 init1: 72 opt: 302 Z-score: 190.4 bits: 44.9 E(85289): 0.00072
Smith-Waterman score: 302; 27.3% identity (51.4% similar) in 414 aa overlap (182-578:24-420)
160 170 180 190 200
pF1KE4 CPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHLWPL-ERYCRAERVCLCEACAAQ-EH
::.: . : .:: : :.: : . :
NP_150 MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAH
10 20 30 40 50
210 220 230 240 250 260
pF1KE4 RGHEL-VPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVS
::: . . :: .:. : . :. . . .. .:.: . .. .:. : . . ..
NP_150 RGHPVGLALEAAVHVQKLSQ-ECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLK
60 70 80 90 100 110
270 280 290 300 310 320
pF1KE4 RLFADAAAALQGFQTQVLGFIEEGEAAMLG--RSQGD-LRRQEEQRSRLSRARQNLSQVP
:.. :. .. . ::... : : :.: :.: . . :: ..:: :
NP_150 GKFTELRLLLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEP
120 130 140 150 160 170
330 340 350 360 370 380
pF1KE4 EADSVSFLQELLALRLALEDGCGPGP-GPPRELSFTKSSQAVRAVRDMLAVACVNQWEQL
: :. :: : . ... . : : ::: . :.. :. : . .
NP_150 --DPVQRLQAYTATEQEMQQQMSLGELCHPVPLSF----EPVKSFFKGLVEAVESTLQTP
180 190 200 210 220
390 400 410 420 430 440
pF1KE4 RGPGGNEDGPQKLDSEADAEPQDLESTNLLESEAP-RDYFLKFAYIVDLDSDTADKFLQL
.:. .:.. ....: : .: : .: :. .::.: :: :: :.:
NP_150 LDIRLKESINCQLSDPSSTKPGTLLKT----SPSPERSLLLKYARTPTLDPDTMHARLRL
230 240 250 260 270 280
450 460 470 480 490
pF1KE4 FGTKGVKRVLCPINYPLSPT---RFTHCEQVLGEGALDRGTYYWEVEIIE---GWVSMGV
. . . : : . :.:. :: :::.. . : .::::.. : :: .:.
NP_150 SADRLTVR--CGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWW-VGA
290 300 310 320 330
500 510 520 530 540 550
pF1KE4 MAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVW-FH-GLEAPL-PHPFSPTVGVCLEY
.. . .::: : .: ::. .. : :: : .. : :. .:: :.:
NP_150 AYASLRRRGASAAARLGCNRQSWCLKR--YDLEYWAFHDGQRSRLRPRDDLDRLGVFLDY
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE4 ADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSHFAGLFTHRLKPAFF
.:::: : : :: :. ..:.
NP_150 EAGVLAFYDVTGG-MSHLHTFRATFQEPLYPALRLWEGAISIPRLP
400 410 420 430 440
>>NP_055603 (OMIM: 606556) tripartite motif-containing p (442 aa)
initn: 141 init1: 72 opt: 302 Z-score: 190.4 bits: 44.9 E(85289): 0.00072
Smith-Waterman score: 302; 27.3% identity (51.4% similar) in 414 aa overlap (182-578:24-420)
160 170 180 190 200
pF1KE4 CPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHLWPL-ERYCRAERVCLCEACAAQ-EH
::.: . : .:: : :.: : . :
NP_055 MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAH
10 20 30 40 50
210 220 230 240 250 260
pF1KE4 RGHEL-VPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVS
::: . . :: .:. : . :. . . .. .:.: . .. .:. : . . ..
NP_055 RGHPVGLALEAAVHVQKLSQ-ECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLK
60 70 80 90 100 110
270 280 290 300 310 320
pF1KE4 RLFADAAAALQGFQTQVLGFIEEGEAAMLG--RSQGD-LRRQEEQRSRLSRARQNLSQVP
:.. :. .. . ::... : : :.: :.: . . :: ..:: :
NP_055 GKFTELRLLLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEP
120 130 140 150 160 170
330 340 350 360 370 380
pF1KE4 EADSVSFLQELLALRLALEDGCGPGP-GPPRELSFTKSSQAVRAVRDMLAVACVNQWEQL
: :. :: : . ... . : : ::: . :.. :. : . .
NP_055 --DPVQRLQAYTATEQEMQQQMSLGELCHPVPLSF----EPVKSFFKGLVEAVESTLQTP
180 190 200 210 220
390 400 410 420 430 440
pF1KE4 RGPGGNEDGPQKLDSEADAEPQDLESTNLLESEAP-RDYFLKFAYIVDLDSDTADKFLQL
.:. .:.. ....: : .: : .: :. .::.: :: :: :.:
NP_055 LDIRLKESINCQLSDPSSTKPGTLLKT----SPSPERSLLLKYARTPTLDPDTMHARLRL
230 240 250 260 270 280
450 460 470 480 490
pF1KE4 FGTKGVKRVLCPINYPLSPT---RFTHCEQVLGEGALDRGTYYWEVEIIE---GWVSMGV
. . . : : . :.:. :: :::.. . : .::::.. : :: .:.
NP_055 SADRLTVR--CGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWW-VGA
290 300 310 320 330
500 510 520 530 540 550
pF1KE4 MAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVW-FH-GLEAPL-PHPFSPTVGVCLEY
.. . .::: : .: ::. .. : :: : .. : :. .:: :.:
NP_055 AYASLRRRGASAAARLGCNRQSWCLKR--YDLEYWAFHDGQRSRLRPRDDLDRLGVFLDY
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE4 ADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSHFAGLFTHRLKPAFF
.:::: : : :: :. ..:.
NP_055 EAGVLAFYDVTGG-MSHLHTFRATFQEPLYPALRLWEGAISIPRLP
400 410 420 430 440
638 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 22:54:39 2016 done: Sat Nov 5 22:54:41 2016
Total Scan time: 11.550 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]