FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4158, 532 aa
  1>>>pF1KE4158 532 - 532 aa - 532 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.9566+/-0.000995; mu= 10.0513+/- 0.059
 mean_var=109.4787+/-23.287, 0's: 0 Z-trim(106.1): 85  B-trim: 0 in 0/51
 Lambda= 0.122577
 statistics sampled from 8737 (8816) to 8737 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.271), width:  16
 Scan time:  3.120

The best scores are:                                      opt bits E(32554)
CCDS44988.1 FBXW8 gene_id:26259|Hs108|chr12        ( 532) 3614 650.4 1.5e-186
CCDS9182.1 FBXW8 gene_id:26259|Hs108|chr12         ( 598) 3344 602.7 3.8e-172


>>CCDS44988.1 FBXW8 gene_id:26259|Hs108|chr12             (532 aa)
 initn: 3614 init1: 3614 opt: 3614  Z-score: 3462.9  bits: 650.4 E(32554): 1.5e-186
Smith-Waterman score: 3614; 99.8% identity (100.0% similar) in 532 aa overlap (1-532:1-532)

               10        20        30        40        50        60
pF1KE4 MDDYSLDEFRRRWQEELAQAQAPKKRRRPEAAERRARRPENEMNDVPFFDIQLPYELAIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MDDYSLDEFRRRWQEELAQAQAPKKRRRPEAAERRARRPENEMNDVPFFDIQLPYELAIN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 IFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRLCQQEGHLPDSSISDYSCWKLIFQECRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRLCQQEGHLPDSSISDYSCWKLIFQECRA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 KEHMLQTNWKNRKGAVSELEHVPDTVLCDVHSHDGVVIAGYTSGDVRVWDTRTWDYVAPF
       :::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KEHMLRTNWKNRKGAVSELEHVPDTVLCDVHSHDGVVIAGYTSGDVRVWDTRTWDYVAPF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 LESEDEEDEPGMQPNVSFVRINSSLAVAAYEDGFLNIWDLRTGKYPVHRFEHDARIQALA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LESEDEEDEPGMQPNVSFVRINSSLAVAAYEDGFLNIWDLRTGKYPVHRFEHDARIQALA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 LSQDDATVATASAFDVVMLSPNEEGYWQIAAEFEVPKLVQYLEIVPETRRYPVAVAAAGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LSQDDATVATASAFDVVMLSPNEEGYWQIAAEFEVPKLVQYLEIVPETRRYPVAVAAAGD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE4 LMYLLKAEDSARTLLYAHGPPVTCLDVSANQVAFGVQGLGWVYEGSKILVYSLEAGRRLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LMYLLKAEDSARTLLYAHGPPVTCLDVSANQVAFGVQGLGWVYEGSKILVYSLEAGRRLL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE4 KLGNVLRDFTCVNLSDSPPNLMVSGNMDGRVRIHDLRSGNIALSLSAHQLRVSAVQMDDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KLGNVLRDFTCVNLSDSPPNLMVSGNMDGRVRIHDLRSGNIALSLSAHQLRVSAVQMDDW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE4 KIVSGGEEGLVSVWDYRMNQKLWEVYSGHPVQHISFSSHSLITANVPYQTVMRNADLDSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KIVSGGEEGLVSVWDYRMNQKLWEVYSGHPVQHISFSSHSLITANVPYQTVMRNADLDSF
              430       440       450       460       470       480

              490       500       510       520       530  
pF1KE4 TTHRRHRGLIRAYEFAVDQLAFQSPLPVCRSSCDAMATHYYDLALAFPYNHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TTHRRHRGLIRAYEFAVDQLAFQSPLPVCRSSCDAMATHYYDLALAFPYNHV
              490       500       510       520       530  

>>CCDS9182.1 FBXW8 gene_id:26259|Hs108|chr12              (598 aa)
 initn: 3341 init1: 3341 opt: 3344  Z-score: 3204.0  bits: 602.7 E(32554): 3.8e-172
Smith-Waterman score: 3344; 94.5% identity (97.0% similar) in 526 aa overlap (10-532:73-598)

                                    10        20        30         
pF1KE4                      MDDYSLDEFRRRWQEELAQAQAPKKRRRPEAAERRAR--
                                     : . :.  .....:  :.   ..:. .   
CCDS91 SGRGEQASGDPALAQRLLEGAGRPPAARATRAEGQDVASRSRSPLAREGAGGGEQLVDQL
             50        60        70        80        90       100  

         40        50        60        70        80        90      
pF1KE4 -RPENEMNDVPFFDIQLPYELAINIFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRLCQQ
        :  ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 IRDLNEMNDVPFFDIQLPYELAINIFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRLCQQ
            110       120       130       140       150       160  

        100       110       120       130       140       150      
pF1KE4 EGHLPDSSISDYSCWKLIFQECRAKEHMLQTNWKNRKGAVSELEHVPDTVLCDVHSHDGV
       :::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
CCDS91 EGHLPDSSISDYSCWKLIFQECRAKEHMLRTNWKNRKGAVSELEHVPDTVLCDVHSHDGV
            170       180       190       200       210       220  

        160       170       180       190       200       210      
pF1KE4 VIAGYTSGDVRVWDTRTWDYVAPFLESEDEEDEPGMQPNVSFVRINSSLAVAAYEDGFLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 VIAGYTSGDVRVWDTRTWDYVAPFLESEDEEDEPGMQPNVSFVRINSSLAVAAYEDGFLN
            230       240       250       260       270       280  

        220       230       240       250       260       270      
pF1KE4 IWDLRTGKYPVHRFEHDARIQALALSQDDATVATASAFDVVMLSPNEEGYWQIAAEFEVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 IWDLRTGKYPVHRFEHDARIQALALSQDDATVATASAFDVVMLSPNEEGYWQIAAEFEVP
            290       300       310       320       330       340  

        280       290       300       310       320       330      
pF1KE4 KLVQYLEIVPETRRYPVAVAAAGDLMYLLKAEDSARTLLYAHGPPVTCLDVSANQVAFGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 KLVQYLEIVPETRRYPVAVAAAGDLMYLLKAEDSARTLLYAHGPPVTCLDVSANQVAFGV
            350       360       370       380       390       400  

        340       350       360       370       380       390      
pF1KE4 QGLGWVYEGSKILVYSLEAGRRLLKLGNVLRDFTCVNLSDSPPNLMVSGNMDGRVRIHDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 QGLGWVYEGSKILVYSLEAGRRLLKLGNVLRDFTCVNLSDSPPNLMVSGNMDGRVRIHDL
            410       420       430       440       450       460  

        400       410       420       430       440       450      
pF1KE4 RSGNIALSLSAHQLRVSAVQMDDWKIVSGGEEGLVSVWDYRMNQKLWEVYSGHPVQHISF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 RSGNIALSLSAHQLRVSAVQMDDWKIVSGGEEGLVSVWDYRMNQKLWEVYSGHPVQHISF
            470       480       490       500       510       520  

        460       470       480       490       500       510      
pF1KE4 SSHSLITANVPYQTVMRNADLDSFTTHRRHRGLIRAYEFAVDQLAFQSPLPVCRSSCDAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 SSHSLITANVPYQTVMRNADLDSFTTHRRHRGLIRAYEFAVDQLAFQSPLPVCRSSCDAM
            530       540       550       560       570       580  

        520       530  
pF1KE4 ATHYYDLALAFPYNHV
       ::::::::::::::::
CCDS91 ATHYYDLALAFPYNHV
            590        




532 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 01:48:31 2016 done: Sun Nov  6 01:48:31 2016
 Total Scan time:  3.120 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]