Result of FASTA (omim) for
pFN21AE4130
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4130, 527 aa
1>>>pF1KE4130 527 - 527 aa - 527 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8085+/-0.000453; mu= 16.2754+/- 0.028
mean_var=101.8730+/-21.311, 0's: 0 Z-trim(112.6): 112 B-trim: 1005 in 1/50
Lambda= 0.127071
statistics sampled from 21418 (21531) to 21418 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.252), width: 16
Scan time: 8.090
The best scores are: opt bits E(85289)
NP_003184 (OMIM: 241410,244460,604934) tubulin-spe ( 527) 3496 652.1 1.1e-186
NP_001072983 (OMIM: 241410,244460,604934) tubulin- ( 527) 3496 652.1 1.1e-186
NP_001274731 (OMIM: 241410,244460,604934) tubulin- ( 414) 2648 496.6 6e-140
NP_001274730 (OMIM: 241410,244460,604934) tubulin- ( 578) 2049 386.9 8.8e-107
NP_689928 (OMIM: 610451) tubulin-specific chaperon ( 424) 403 85.0 4.8e-16
XP_016872815 (OMIM: 610451) PREDICTED: tubulin-spe ( 424) 403 85.0 4.8e-16
NP_001123519 (OMIM: 610451) tubulin-specific chape ( 424) 403 85.0 4.8e-16
NP_001186499 (OMIM: 607382) CAP-Gly domain-contain ( 547) 171 42.6 0.0037
NP_056341 (OMIM: 607382) CAP-Gly domain-containing ( 547) 171 42.6 0.0037
>>NP_003184 (OMIM: 241410,244460,604934) tubulin-specifi (527 aa)
initn: 3496 init1: 3496 opt: 3496 Z-score: 3472.3 bits: 652.1 E(85289): 1.1e-186
Smith-Waterman score: 3496; 100.0% identity (100.0% similar) in 527 aa overlap (1-527:1-527)
10 20 30 40 50 60
pF1KE4 MSDTLTADVIGRRVEVNGEHATVRFAGVVPPVAGPWLGVEWDNPERGKHDGSHEGTVYFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSDTLTADVIGRRVEVNGEHATVRFAGVVPPVAGPWLGVEWDNPERGKHDGSHEGTVYFK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 CRHPTGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEEDRKEQIVTIGNKPVETIGFDSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CRHPTGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEEDRKEQIVTIGNKPVETIGFDSIM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KQQSQLSKLQEVSLRNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSSWDEVIHIADQLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KQQSQLSKLQEVSLRNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSSWDEVIHIADQLRH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LEVLNVSENKLKFPSGSVLTGTLSVLKVLVLNQTGITWAEVLRCVAGCPGLEELYLESNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LEVLNVSENKLKFPSGSVLTGTLSVLKVLVLNQTGITWAEVLRCVAGCPGLEELYLESNN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 IFISERPTDVLQTVKLLDLSSNQLIDENQLYLIAHLPRLEQLILSDTGISSLHFPDAGIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IFISERPTDVLQTVKLLDLSSNQLIDENQLYLIAHLPRLEQLILSDTGISSLHFPDAGIG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 CKTSMFPSLKYLVVNDNQISQWSFFNELEKLPSLRALSCLRNPLTKEDKEAETARLLIIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CKTSMFPSLKYLVVNDNQISQWSFFNELEKLPSLRALSCLRNPLTKEDKEAETARLLIIA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 SIGQLKTLNKCEILPEERRRAELDYRKAFGNEWKQAGGHKDPEKNRLSEEFLTAHPRYQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SIGQLKTLNKCEILPEERRRAELDYRKAFGNEWKQAGGHKDPEKNRLSEEFLTAHPRYQF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 LCLKYGAPEDWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLEKQLPGSMTIQKVKGLLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LCLKYGAPEDWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLEKQLPGSMTIQKVKGLLSR
430 440 450 460 470 480
490 500 510 520
pF1KE4 LLKVPVSDLLLSYESPKKPGREIELENDLKSLQFYSVENGDCLLVRW
:::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LLKVPVSDLLLSYESPKKPGREIELENDLKSLQFYSVENGDCLLVRW
490 500 510 520
>>NP_001072983 (OMIM: 241410,244460,604934) tubulin-spec (527 aa)
initn: 3496 init1: 3496 opt: 3496 Z-score: 3472.3 bits: 652.1 E(85289): 1.1e-186
Smith-Waterman score: 3496; 100.0% identity (100.0% similar) in 527 aa overlap (1-527:1-527)
10 20 30 40 50 60
pF1KE4 MSDTLTADVIGRRVEVNGEHATVRFAGVVPPVAGPWLGVEWDNPERGKHDGSHEGTVYFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSDTLTADVIGRRVEVNGEHATVRFAGVVPPVAGPWLGVEWDNPERGKHDGSHEGTVYFK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 CRHPTGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEEDRKEQIVTIGNKPVETIGFDSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRHPTGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEEDRKEQIVTIGNKPVETIGFDSIM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KQQSQLSKLQEVSLRNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSSWDEVIHIADQLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQQSQLSKLQEVSLRNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSSWDEVIHIADQLRH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LEVLNVSENKLKFPSGSVLTGTLSVLKVLVLNQTGITWAEVLRCVAGCPGLEELYLESNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEVLNVSENKLKFPSGSVLTGTLSVLKVLVLNQTGITWAEVLRCVAGCPGLEELYLESNN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 IFISERPTDVLQTVKLLDLSSNQLIDENQLYLIAHLPRLEQLILSDTGISSLHFPDAGIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFISERPTDVLQTVKLLDLSSNQLIDENQLYLIAHLPRLEQLILSDTGISSLHFPDAGIG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 CKTSMFPSLKYLVVNDNQISQWSFFNELEKLPSLRALSCLRNPLTKEDKEAETARLLIIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKTSMFPSLKYLVVNDNQISQWSFFNELEKLPSLRALSCLRNPLTKEDKEAETARLLIIA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 SIGQLKTLNKCEILPEERRRAELDYRKAFGNEWKQAGGHKDPEKNRLSEEFLTAHPRYQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIGQLKTLNKCEILPEERRRAELDYRKAFGNEWKQAGGHKDPEKNRLSEEFLTAHPRYQF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 LCLKYGAPEDWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLEKQLPGSMTIQKVKGLLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCLKYGAPEDWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLEKQLPGSMTIQKVKGLLSR
430 440 450 460 470 480
490 500 510 520
pF1KE4 LLKVPVSDLLLSYESPKKPGREIELENDLKSLQFYSVENGDCLLVRW
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKVPVSDLLLSYESPKKPGREIELENDLKSLQFYSVENGDCLLVRW
490 500 510 520
>>NP_001274731 (OMIM: 241410,244460,604934) tubulin-spec (414 aa)
initn: 2648 init1: 2648 opt: 2648 Z-score: 2633.5 bits: 496.6 E(85289): 6e-140
Smith-Waterman score: 2648; 100.0% identity (100.0% similar) in 404 aa overlap (124-527:11-414)
100 110 120 130 140 150
pF1KE4 GPEEDRKEQIVTIGNKPVETIGFDSIMKQQSQLSKLQEVSLRNCAVSCAGEKGGVAEACP
::::::::::::::::::::::::::::::
NP_001 MYPCELCFSCSQLSKLQEVSLRNCAVSCAGEKGGVAEACP
10 20 30 40
160 170 180 190 200 210
pF1KE4 NIRKVDLSKNLLSSWDEVIHIADQLRHLEVLNVSENKLKFPSGSVLTGTLSVLKVLVLNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIRKVDLSKNLLSSWDEVIHIADQLRHLEVLNVSENKLKFPSGSVLTGTLSVLKVLVLNQ
50 60 70 80 90 100
220 230 240 250 260 270
pF1KE4 TGITWAEVLRCVAGCPGLEELYLESNNIFISERPTDVLQTVKLLDLSSNQLIDENQLYLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGITWAEVLRCVAGCPGLEELYLESNNIFISERPTDVLQTVKLLDLSSNQLIDENQLYLI
110 120 130 140 150 160
280 290 300 310 320 330
pF1KE4 AHLPRLEQLILSDTGISSLHFPDAGIGCKTSMFPSLKYLVVNDNQISQWSFFNELEKLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHLPRLEQLILSDTGISSLHFPDAGIGCKTSMFPSLKYLVVNDNQISQWSFFNELEKLPS
170 180 190 200 210 220
340 350 360 370 380 390
pF1KE4 LRALSCLRNPLTKEDKEAETARLLIIASIGQLKTLNKCEILPEERRRAELDYRKAFGNEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRALSCLRNPLTKEDKEAETARLLIIASIGQLKTLNKCEILPEERRRAELDYRKAFGNEW
230 240 250 260 270 280
400 410 420 430 440 450
pF1KE4 KQAGGHKDPEKNRLSEEFLTAHPRYQFLCLKYGAPEDWELKTQQPLMLKNQLLTLKIKYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQAGGHKDPEKNRLSEEFLTAHPRYQFLCLKYGAPEDWELKTQQPLMLKNQLLTLKIKYP
290 300 310 320 330 340
460 470 480 490 500 510
pF1KE4 HQLDQKVLEKQLPGSMTIQKVKGLLSRLLKVPVSDLLLSYESPKKPGREIELENDLKSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQLDQKVLEKQLPGSMTIQKVKGLLSRLLKVPVSDLLLSYESPKKPGREIELENDLKSLQ
350 360 370 380 390 400
520
pF1KE4 FYSVENGDCLLVRW
::::::::::::::
NP_001 FYSVENGDCLLVRW
410
>>NP_001274730 (OMIM: 241410,244460,604934) tubulin-spec (578 aa)
initn: 2035 init1: 2035 opt: 2049 Z-score: 2038.1 bits: 386.9 E(85289): 8.8e-107
Smith-Waterman score: 3267; 90.9% identity (90.9% similar) in 559 aa overlap (20-527:20-578)
10 20 30 40 50 60
pF1KE4 MSDTLTADVIGRRVEVNGEHATVRFAGVVPPVAGPWLGVEWDNPERGKHDGSHEGTVYFK
:::::::::::::::::::::::::::::::::::::::::
NP_001 MSDTLTADVIGRRVEVNGEHATVRFAGVVPPVAGPWLGVEWDNPERGKHDGSHEGTVYFK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 CRHPTGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEEDRKEQIVTIGNKPVETIGFDSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRHPTGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEEDRKEQIVTIGNKPVETIGFDSIM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 KQQSQLSKLQEVSLRNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSSWDEVIHIADQLRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQQSQLSKLQEVSLRNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSSWDEVIHIADQLRH
130 140 150 160 170 180
190 200 210 220
pF1KE4 LEVLNVSENKLKFPSGSVLTGTLSVLKVLVLNQTGITWAE--------------------
::::::::::::::::::::::::::::::::::::::::
NP_001 LEVLNVSENKLKFPSGSVLTGTLSVLKVLVLNQTGITWAEAHAQCGGSRHGLDMQKDASK
190 200 210 220 230 240
230 240
pF1KE4 -------------------------------VLRCVAGCPGLEELYLESNNIFISERPTD
:::::::::::::::::::::::::::::
NP_001 FVDLCVLQKCSTSNCIISAKDHTSMRMNVAKVLRCVAGCPGLEELYLESNNIFISERPTD
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE4 VLQTVKLLDLSSNQLIDENQLYLIAHLPRLEQLILSDTGISSLHFPDAGIGCKTSMFPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQTVKLLDLSSNQLIDENQLYLIAHLPRLEQLILSDTGISSLHFPDAGIGCKTSMFPSL
310 320 330 340 350 360
310 320 330 340 350 360
pF1KE4 KYLVVNDNQISQWSFFNELEKLPSLRALSCLRNPLTKEDKEAETARLLIIASIGQLKTLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYLVVNDNQISQWSFFNELEKLPSLRALSCLRNPLTKEDKEAETARLLIIASIGQLKTLN
370 380 390 400 410 420
370 380 390 400 410 420
pF1KE4 KCEILPEERRRAELDYRKAFGNEWKQAGGHKDPEKNRLSEEFLTAHPRYQFLCLKYGAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCEILPEERRRAELDYRKAFGNEWKQAGGHKDPEKNRLSEEFLTAHPRYQFLCLKYGAPE
430 440 450 460 470 480
430 440 450 460 470 480
pF1KE4 DWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLEKQLPGSMTIQKVKGLLSRLLKVPVSDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLEKQLPGSMTIQKVKGLLSRLLKVPVSDL
490 500 510 520 530 540
490 500 510 520
pF1KE4 LLSYESPKKPGREIELENDLKSLQFYSVENGDCLLVRW
::::::::::::::::::::::::::::::::::::::
NP_001 LLSYESPKKPGREIELENDLKSLQFYSVENGDCLLVRW
550 560 570
>>NP_689928 (OMIM: 610451) tubulin-specific chaperone co (424 aa)
initn: 293 init1: 137 opt: 403 Z-score: 409.1 bits: 85.0 E(85289): 4.8e-16
Smith-Waterman score: 464; 26.5% identity (58.7% similar) in 453 aa overlap (78-525:6-419)
50 60 70 80 90 100
pF1KE4 KHDGSHEGTVYFKCRHPTGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEEDRKEQIVTIG
: .:. .. ..: :. : . . : .
NP_689 MDQPSGRSFMQVLCEKYSPENFPYRRGPGMGVHV-
10 20 30
110 120 130 140 150 160
pF1KE4 NKPVETIGFDSIMKQQSQLSKLQEVSLRNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSS
:. : : ::.. .: .. . : .:...:::.. .: : .. ..::: : : .
NP_689 --PATPQG--SPMKDRLNLPSV--LVLNSCGITCAGDEKEIAAFCAHVSELDLSDNKLED
40 50 60 70 80
170 180 190 200 210 220
pF1KE4 WDEVIHIADQLRHLEVLNVSENKLKFPSGSVL----TGTLSVLKVLVLNQTGITWAEVLR
: :: .:.... .:: ::.: : :.. ::: .:..: .. ::::.. .: :
NP_689 WHEVSKIVSNVPQLEFLNLSSNPLNL---SVLERTCAGSFSGVRKLVLNNSKASWETVHM
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE4 CVAGCPGLEELYLESNNIFISERPTDVLQTVKLLDLSSNQLIDENQLY-LIAHLPRLEQL
. : ::::.: :. :. ...::: ...:.: : ... : . .: :. :
NP_689 ILQELPDLEELFLCLNDYETVSCPSICCHSLKLLHITDNNLQDWTEIRKLGVMFPSLDTL
150 160 170 180 190 200
290 300 310 320 330 340
pF1KE4 ILSDTGISSLHFPDAGIGCKTSMFPSLKYLVVNDNQISQWSFFNELEKLPSLRALSCLRN
.:... ..... :: ... .::.:. . .. . ...: ...:...:.:. . :
NP_689 VLANNHLNAIEEPDDSLA---RLFPNLRSISLHKSGLQSWEDIDKLNSFPKLEEVRLLGI
210 220 230 240 250 260
350 360 370 380 390 400
pF1KE4 PLTKEDKEAETARLLIIASIGQLKTLNKCEILPEERRRAELDYRKAFGNEWKQAGGHKDP
:: . .: : :.:: . ... :: . ::. : .. : . .. .. :
NP_689 PLLQP-YTTEERRKLVIARLPSVSKLNGSVVTDGERE----DSERFFIRYYVDVPQEEVP
270 280 290 300 310
410 420 430 440 450 460
pF1KE4 EKNRLSEEFLTAHPRYQFLCLKYGAPEDWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLE
: ::. : ::: .:. . :. : . :.. : :: : :
NP_689 --------F-----RYHELITKYG-----KLEPLAEVDLRPQS-SAKVEV-HFNDQ-VEE
320 330 340 350
470 480 490 500 510 520
pF1KE4 KQLPGSMTIQKVKGLLSRLLKVPVSDLLLSYESPKKPGREIELENDLKSLQFYSVENGDC
.. ..:. ..: :. :...:.:..:: : . . : :.. . ..:. .....::
NP_689 MSIRLDQTVAELKKQLKTLVQLPTSNMLLYYFDHEAPFGPEEMKYSSRALHSFGIRDGDK
360 370 380 390 400 410
pF1KE4 LLVRW
. :
NP_689 IYVESKTK
420
>>XP_016872815 (OMIM: 610451) PREDICTED: tubulin-specifi (424 aa)
initn: 293 init1: 137 opt: 403 Z-score: 409.1 bits: 85.0 E(85289): 4.8e-16
Smith-Waterman score: 464; 26.5% identity (58.7% similar) in 453 aa overlap (78-525:6-419)
50 60 70 80 90 100
pF1KE4 KHDGSHEGTVYFKCRHPTGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEEDRKEQIVTIG
: .:. .. ..: :. : . . : .
XP_016 MDQPSGRSFMQVLCEKYSPENFPYRRGPGMGVHV-
10 20 30
110 120 130 140 150 160
pF1KE4 NKPVETIGFDSIMKQQSQLSKLQEVSLRNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSS
:. : : ::.. .: .. . : .:...:::.. .: : .. ..::: : : .
XP_016 --PATPQG--SPMKDRLNLPSV--LVLNSCGITCAGDEKEIAAFCAHVSELDLSDNKLED
40 50 60 70 80
170 180 190 200 210 220
pF1KE4 WDEVIHIADQLRHLEVLNVSENKLKFPSGSVL----TGTLSVLKVLVLNQTGITWAEVLR
: :: .:.... .:: ::.: : :.. ::: .:..: .. ::::.. .: :
XP_016 WHEVSKIVSNVPQLEFLNLSSNPLNL---SVLERTCAGSFSGVRKLVLNNSKASWETVHM
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE4 CVAGCPGLEELYLESNNIFISERPTDVLQTVKLLDLSSNQLIDENQLY-LIAHLPRLEQL
. : ::::.: :. :. ...::: ...:.: : ... : . .: :. :
XP_016 ILQELPDLEELFLCLNDYETVSCPSICCHSLKLLHITDNNLQDWTEIRKLGVMFPSLDTL
150 160 170 180 190 200
290 300 310 320 330 340
pF1KE4 ILSDTGISSLHFPDAGIGCKTSMFPSLKYLVVNDNQISQWSFFNELEKLPSLRALSCLRN
.:... ..... :: ... .::.:. . .. . ...: ...:...:.:. . :
XP_016 VLANNHLNAIEEPDDSLA---RLFPNLRSISLHKSGLQSWEDIDKLNSFPKLEEVRLLGI
210 220 230 240 250 260
350 360 370 380 390 400
pF1KE4 PLTKEDKEAETARLLIIASIGQLKTLNKCEILPEERRRAELDYRKAFGNEWKQAGGHKDP
:: . .: : :.:: . ... :: . ::. : .. : . .. .. :
XP_016 PLLQP-YTTEERRKLVIARLPSVSKLNGSVVTDGERE----DSERFFIRYYVDVPQEEVP
270 280 290 300 310
410 420 430 440 450 460
pF1KE4 EKNRLSEEFLTAHPRYQFLCLKYGAPEDWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLE
: ::. : ::: .:. . :. : . :.. : :: : :
XP_016 --------F-----RYHELITKYG-----KLEPLAEVDLRPQS-SAKVEV-HFNDQ-VEE
320 330 340 350
470 480 490 500 510 520
pF1KE4 KQLPGSMTIQKVKGLLSRLLKVPVSDLLLSYESPKKPGREIELENDLKSLQFYSVENGDC
.. ..:. ..: :. :...:.:..:: : . . : :.. . ..:. .....::
XP_016 MSIRLDQTVAELKKQLKTLVQLPTSNMLLYYFDHEAPFGPEEMKYSSRALHSFGIRDGDK
360 370 380 390 400 410
pF1KE4 LLVRW
. :
XP_016 IYVESKTK
420
>>NP_001123519 (OMIM: 610451) tubulin-specific chaperone (424 aa)
initn: 293 init1: 137 opt: 403 Z-score: 409.1 bits: 85.0 E(85289): 4.8e-16
Smith-Waterman score: 464; 26.5% identity (58.7% similar) in 453 aa overlap (78-525:6-419)
50 60 70 80 90 100
pF1KE4 KHDGSHEGTVYFKCRHPTGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEEDRKEQIVTIG
: .:. .. ..: :. : . . : .
NP_001 MDQPSGRSFMQVLCEKYSPENFPYRRGPGMGVHV-
10 20 30
110 120 130 140 150 160
pF1KE4 NKPVETIGFDSIMKQQSQLSKLQEVSLRNCAVSCAGEKGGVAEACPNIRKVDLSKNLLSS
:. : : ::.. .: .. . : .:...:::.. .: : .. ..::: : : .
NP_001 --PATPQG--SPMKDRLNLPSV--LVLNSCGITCAGDEKEIAAFCAHVSELDLSDNKLED
40 50 60 70 80
170 180 190 200 210 220
pF1KE4 WDEVIHIADQLRHLEVLNVSENKLKFPSGSVL----TGTLSVLKVLVLNQTGITWAEVLR
: :: .:.... .:: ::.: : :.. ::: .:..: .. ::::.. .: :
NP_001 WHEVSKIVSNVPQLEFLNLSSNPLNL---SVLERTCAGSFSGVRKLVLNNSKASWETVHM
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE4 CVAGCPGLEELYLESNNIFISERPTDVLQTVKLLDLSSNQLIDENQLY-LIAHLPRLEQL
. : ::::.: :. :. ...::: ...:.: : ... : . .: :. :
NP_001 ILQELPDLEELFLCLNDYETVSCPSICCHSLKLLHITDNNLQDWTEIRKLGVMFPSLDTL
150 160 170 180 190 200
290 300 310 320 330 340
pF1KE4 ILSDTGISSLHFPDAGIGCKTSMFPSLKYLVVNDNQISQWSFFNELEKLPSLRALSCLRN
.:... ..... :: ... .::.:. . .. . ...: ...:...:.:. . :
NP_001 VLANNHLNAIEEPDDSLA---RLFPNLRSISLHKSGLQSWEDIDKLNSFPKLEEVRLLGI
210 220 230 240 250 260
350 360 370 380 390 400
pF1KE4 PLTKEDKEAETARLLIIASIGQLKTLNKCEILPEERRRAELDYRKAFGNEWKQAGGHKDP
:: . .: : :.:: . ... :: . ::. : .. : . .. .. :
NP_001 PLLQP-YTTEERRKLVIARLPSVSKLNGSVVTDGERE----DSERFFIRYYVDVPQEEVP
270 280 290 300 310
410 420 430 440 450 460
pF1KE4 EKNRLSEEFLTAHPRYQFLCLKYGAPEDWELKTQQPLMLKNQLLTLKIKYPHQLDQKVLE
: ::. : ::: .:. . :. : . :.. : :: : :
NP_001 --------F-----RYHELITKYG-----KLEPLAEVDLRPQS-SAKVEV-HFNDQ-VEE
320 330 340 350
470 480 490 500 510 520
pF1KE4 KQLPGSMTIQKVKGLLSRLLKVPVSDLLLSYESPKKPGREIELENDLKSLQFYSVENGDC
.. ..:. ..: :. :...:.:..:: : . . : :.. . ..:. .....::
NP_001 MSIRLDQTVAELKKQLKTLVQLPTSNMLLYYFDHEAPFGPEEMKYSSRALHSFGIRDGDK
360 370 380 390 400 410
pF1KE4 LLVRW
. :
NP_001 IYVESKTK
420
>>NP_001186499 (OMIM: 607382) CAP-Gly domain-containing (547 aa)
initn: 191 init1: 88 opt: 171 Z-score: 177.7 bits: 42.6 E(85289): 0.0037
Smith-Waterman score: 171; 41.7% identity (69.4% similar) in 72 aa overlap (10-80:296-365)
10 20 30
pF1KE4 MSDTLTADVIGRRVEVNGEHA-TVRFAGVVPPVAGPWLG
.: :: ..:... :.:: :.. ..: :.:
NP_001 VPLSCALPKVTLPNYDNVPGNLMLSALGLRLGDRVLLDGQKTGTLRFCGTTEFASGQWVG
270 280 290 300 310 320
40 50 60 70 80 90
pF1KE4 VEWDNPERGKHDGSHEGTVYFKCRHPTGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEED
:: :.:: ::.::: :. :: : : : : .:.. ..:
NP_001 VELDEPE-GKNDGSVGGVRYFIC-PPKQGLFASVSKISKAVDAPPSSVTSTPRTPRMDFS
330 340 350 360 370 380
100 110 120 130 140 150
pF1KE4 RKEQIVTIGNKPVETIGFDSIMKQQSQLSKLQEVSLRNCAVSCAGEKGGVAEACPNIRKV
NP_001 RVTGKGRREHKGKKKTPSSPSLGSLQQRDGAKAEVGDQVLVAGQKQGIVRFYGKTDFAPG
390 400 410 420 430 440
>>NP_056341 (OMIM: 607382) CAP-Gly domain-containing lin (547 aa)
initn: 191 init1: 88 opt: 171 Z-score: 177.7 bits: 42.6 E(85289): 0.0037
Smith-Waterman score: 171; 41.7% identity (69.4% similar) in 72 aa overlap (10-80:296-365)
10 20 30
pF1KE4 MSDTLTADVIGRRVEVNGEHA-TVRFAGVVPPVAGPWLG
.: :: ..:... :.:: :.. ..: :.:
NP_056 VPLSCALPKVTLPNYDNVPGNLMLSALGLRLGDRVLLDGQKTGTLRFCGTTEFASGQWVG
270 280 290 300 310 320
40 50 60 70 80 90
pF1KE4 VEWDNPERGKHDGSHEGTVYFKCRHPTGGSFIRPNKVNFGTDFLTAIKNRYVLEDGPEED
:: :.:: ::.::: :. :: : : : : .:.. ..:
NP_056 VELDEPE-GKNDGSVGGVRYFIC-PPKQGLFASVSKISKAVDAPPSSVTSTPRTPRMDFS
330 340 350 360 370 380
100 110 120 130 140 150
pF1KE4 RKEQIVTIGNKPVETIGFDSIMKQQSQLSKLQEVSLRNCAVSCAGEKGGVAEACPNIRKV
NP_056 RVTGKGRREHKGKKKTPSSPSLGSLQQRDGAKAEVGDQVLVAGQKQGIVRFYGKTDFAPG
390 400 410 420 430 440
527 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:43:34 2016 done: Sun Nov 6 03:43:35 2016
Total Scan time: 8.090 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]