Result of FASTA (ccds) for
pFN21AE4119
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4119, 474 aa
1>>>pF1KE4119 474 - 474 aa - 474 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4689+/-0.000994; mu= 9.3083+/- 0.060
mean_var=195.1876+/-42.451, 0's: 0 Z-trim(111.3): 145 B-trim: 472 in 1/54
Lambda= 0.091801
statistics sampled from 12068 (12237) to 12068 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.376), width: 16
Scan time: 3.380
The best scores are: opt bits E(32554)
CCDS5678.1 TRIM4 gene_id:89122|Hs108|chr7 ( 474) 3276 446.6 2.7e-125
CCDS5679.1 TRIM4 gene_id:89122|Hs108|chr7 ( 500) 2273 313.8 2.7e-85
CCDS4654.1 TRIM27 gene_id:5987|Hs108|chr6 ( 513) 842 124.2 3.1e-28
CCDS31048.1 TRIM11 gene_id:81559|Hs108|chr1 ( 468) 816 120.8 3.2e-27
CCDS1571.1 TRIM17 gene_id:51127|Hs108|chr1 ( 477) 774 115.2 1.5e-25
CCDS34375.1 TRIM10 gene_id:10107|Hs108|chr6 ( 481) 748 111.8 1.7e-24
CCDS44327.1 TRIM17 gene_id:51127|Hs108|chr1 ( 343) 745 111.2 1.8e-24
CCDS1636.1 TRIM58 gene_id:25893|Hs108|chr1 ( 486) 741 110.8 3.2e-24
CCDS44525.1 TRIM21 gene_id:6737|Hs108|chr11 ( 475) 723 108.5 1.7e-23
CCDS31356.1 TRIM68 gene_id:55128|Hs108|chr11 ( 485) 693 104.5 2.6e-22
CCDS34378.1 TRIM39 gene_id:56658|Hs108|chr6 ( 488) 667 101.0 2.9e-21
CCDS78121.1 RPP21 gene_id:202658|Hs108|chr6 ( 503) 667 101.1 2.9e-21
CCDS31393.1 TRIM5 gene_id:85363|Hs108|chr11 ( 493) 656 99.6 8e-21
CCDS31391.1 TRIM34 gene_id:53840|Hs108|chr11 ( 488) 634 96.7 6e-20
CCDS31388.1 TRIM34 gene_id:445372|Hs108|chr11 ( 842) 634 96.9 8.7e-20
CCDS4676.1 TRIM10 gene_id:10107|Hs108|chr6 ( 395) 624 95.3 1.3e-19
CCDS2015.1 TRIM43 gene_id:129868|Hs108|chr2 ( 446) 623 95.2 1.5e-19
CCDS31390.1 TRIM6 gene_id:117854|Hs108|chr11 ( 488) 617 94.4 2.8e-19
CCDS31389.1 TRIM6 gene_id:117854|Hs108|chr11 ( 516) 617 94.4 2.9e-19
CCDS3808.1 TRIM60 gene_id:166655|Hs108|chr4 ( 471) 610 93.5 5.3e-19
CCDS34377.1 TRIM39 gene_id:56658|Hs108|chr6 ( 518) 602 92.5 1.2e-18
CCDS32220.1 TRIM69 gene_id:140691|Hs108|chr15 ( 500) 601 92.3 1.3e-18
CCDS4568.1 TRIM38 gene_id:10475|Hs108|chr6 ( 465) 597 91.8 1.7e-18
CCDS4462.1 TRIM7 gene_id:81786|Hs108|chr5 ( 511) 570 88.2 2.2e-17
CCDS73363.1 TRIM64 gene_id:120146|Hs108|chr11 ( 449) 568 87.9 2.4e-17
CCDS4677.1 TRIM15 gene_id:89870|Hs108|chr6 ( 465) 567 87.8 2.7e-17
CCDS53694.1 TRIM49C gene_id:642612|Hs108|chr11 ( 452) 560 86.8 5e-17
CCDS55762.1 TRIM49B gene_id:283116|Hs108|chr11 ( 452) 560 86.8 5e-17
CCDS8287.1 TRIM49 gene_id:57093|Hs108|chr11 ( 452) 559 86.7 5.5e-17
CCDS53693.1 TRIM64B gene_id:642446|Hs108|chr11 ( 449) 558 86.6 6e-17
CCDS3851.1 TRIML1 gene_id:339976|Hs108|chr4 ( 468) 558 86.6 6.2e-17
CCDS31392.1 TRIM5 gene_id:85363|Hs108|chr11 ( 326) 554 85.9 7e-17
CCDS31394.1 TRIM5 gene_id:85363|Hs108|chr11 ( 347) 554 85.9 7.3e-17
CCDS60930.1 TRIM49D1 gene_id:399939|Hs108|chr11 ( 452) 544 84.7 2.2e-16
CCDS6056.2 TRIM35 gene_id:23087|Hs108|chr8 ( 493) 544 84.8 2.3e-16
CCDS34374.1 TRIM31 gene_id:11074|Hs108|chr6 ( 425) 536 83.6 4.4e-16
CCDS41612.1 TRIM22 gene_id:10346|Hs108|chr11 ( 498) 518 81.3 2.5e-15
CCDS73287.1 TRIM64C gene_id:646754|Hs108|chr11 ( 450) 512 80.5 4.1e-15
CCDS4466.1 TRIM41 gene_id:90933|Hs108|chr5 ( 630) 493 78.1 3e-14
CCDS4465.1 TRIM41 gene_id:90933|Hs108|chr5 ( 518) 468 74.7 2.6e-13
CCDS32437.1 TRIM72 gene_id:493829|Hs108|chr16 ( 477) 459 73.5 5.6e-13
CCDS60929.1 TRIM77 gene_id:390231|Hs108|chr11 ( 450) 436 70.4 4.4e-12
CCDS376.1 TRIM62 gene_id:55223|Hs108|chr1 ( 475) 421 68.5 1.8e-11
CCDS4614.1 BTN1A1 gene_id:696|Hs108|chr6 ( 526) 409 66.9 5.9e-11
CCDS7947.2 TRIM48 gene_id:79097|Hs108|chr11 ( 224) 397 64.9 9.8e-11
>>CCDS5678.1 TRIM4 gene_id:89122|Hs108|chr7 (474 aa)
initn: 3276 init1: 3276 opt: 3276 Z-score: 2362.9 bits: 446.6 E(32554): 2.7e-125
Smith-Waterman score: 3276; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KE4 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 APIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 APIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 HNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 HNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 NPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 NPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 RYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVES
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 RDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRV
370 380 390 400 410 420
430 440 450 460 470
pF1KE4 GVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFWLSPLASLVIPPVTDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 GVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFWLSPLASLVIPPVTDRK
430 440 450 460 470
>>CCDS5679.1 TRIM4 gene_id:89122|Hs108|chr7 (500 aa)
initn: 3262 init1: 2273 opt: 2273 Z-score: 1644.7 bits: 313.8 E(32554): 2.7e-85
Smith-Waterman score: 3214; 94.8% identity (94.8% similar) in 500 aa overlap (1-474:1-500)
10 20 30 40 50 60
pF1KE4 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM
70 80 90 100 110 120
130 140 150
pF1KE4 APIDEAFESYR--------------------------EKLLKSQRNLVAKMKKVMHLQDV
::::::::::: :::::::::::::::::::::::
CCDS56 APIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHFKQEEKLLKSQRNLVAKMKKVMHLQDV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE4 EVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLN
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE4 QTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 QTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKE
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE4 MLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFV
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE4 ERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE4 WSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 WSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLR
430 440 450 460 470 480
460 470
pF1KE4 PFFWLSPLASLVIPPVTDRK
::::::::::::::::::::
CCDS56 PFFWLSPLASLVIPPVTDRK
490 500
>>CCDS4654.1 TRIM27 gene_id:5987|Hs108|chr6 (513 aa)
initn: 714 init1: 321 opt: 842 Z-score: 620.3 bits: 124.2 E(32554): 3.1e-28
Smith-Waterman score: 887; 32.9% identity (59.9% similar) in 514 aa overlap (3-471:7-493)
10 20 30 40 50
pF1KE4 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPS
:: .:.: :::.::.:: .:. ..::::.: .:: : :. . ::.::.
CCDS46 MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 APAALRPNWALARLTEKT-QRRRLGPVPPG----LCGRHWEPLRLFCEDDQRPVCLVCRE
.::: :: .:. . : : : :: .: .: :::.:.::.:: :.:.:: .
CCDS46 PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR
70 80 90 100 110 120
120 130 140 150 160
pF1KE4 SQEHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKS---
:.::. :.. :..:: :...:.. .: . ..:.: :. . .. : . .. :
CCDS46 SREHRGHSVLPLEEAVEGFKEQI----QNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQ
130 140 150 160 170
170 180 190 200 210 220
pF1KE4 -QRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEV
.: .: :: .:.. : :.: .: ::.. . ...: ... .:. :..:: ..
CCDS46 MEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQL
180 190 200 210 220 230
230 240 250 260
pF1KE4 GEKSQAPTLELLQNPKEVLTRSE-------------IQD-----------VNYSLEAVKV
::.: :: ::::. ..:.:.: .:. .. ::.
CCDS46 EEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTE
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE4 KTVCQIPLMKEM--LKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNY
: .. ..:. . ..: :.: :::.:.:..:.. : :. . .. :
CCDS46 KMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLP--------
300 310 320 330 340
330 340 350 360 370
pF1KE4 FAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVM---GI
:: :::. .:::::. : .:.:::::: :. . ..:::...: :.
CCDS46 ----DNP------ERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGV
350 360 370 380 390
380 390 400 410 420 430
pF1KE4 TDRSKMSPDVGIWAI-YWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAV
:. .:. :.::. : . :: : . : : . :.:::..:: .:.::::...
CCDS46 TS----APQNGFWAVSLWYGKEYWALTS-PMTALPLRTPLQRVGIFLDYDAGEVSFYNVT
400 410 420 430 440 450
440 450 460 470
pF1KE4 DGVHLHTFSCSSV-SRLRPFFWLS-----PLASLVIPPVTDRK
. : ::: .. . .::.: :: : :.: :..
CCDS46 ERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
460 470 480 490 500 510
>>CCDS31048.1 TRIM11 gene_id:81559|Hs108|chr1 (468 aa)
initn: 1059 init1: 399 opt: 816 Z-score: 602.2 bits: 120.8 E(32554): 3.2e-27
Smith-Waterman score: 1078; 39.9% identity (64.1% similar) in 471 aa overlap (5-468:9-451)
10 20 30 40 50
pF1KE4 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPS
..::: :: :::::: ::: .::::::: :..: :. ::. :::::. :
CCDS31 MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 APAALRPNWALARLTEKTQRRRL---GPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQ
:::: ::...: . ::: .::: :.: : ::: :: :. : .: .:..:
CCDS31 PQRNLRPNRPLAKMAEMA--RRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSG
70 80 90 100 110
120 130 140 150 160 170
pF1KE4 EHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRI
:: .: . :...: :. . :: :: ..: .:. .. .: .. . :. ..:::. .
CCDS31 EHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 STEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQA
:: .:. .:.:::. .::::..:: :. .: :.. .:.: : : .:: :. . :
CCDS31 LGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 PTLELLQNPKEVLTRSEIQDVNYSLEAV---KVKTVCQIPLMKEMLKRFQVAVNLAEDTA
:.: :::. :..: : .:::. . : ...:::..: . : :.::. :.: :::
CCDS31 PALGLLQDIKDALRR--VQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 HPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFT
.:.:..:.. : :. .. : .: :::. :::::.. ::
CCDS31 NPELILSEDRRSVQRGDLRQALP------------DSP------ERFDPGPCVLGQERFT
300 310 320 330
360 370 380 390 400 410
pF1KE4 SGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTP
::.:::::: : :.:::::.: . .....: :.: . . .. :. .:
CCDS31 SGRHYWEVEVGDRTSWALGVCRENV-NRKEKGELSAGNGFWILVFLGS-YYNSSERALAP
340 350 360 370 380 390
420 430 440 450 460
pF1KE4 TQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVS-RLRPFFWLSPLASLVIPP
.. : .:::..:: .:..:::::.:: : : : :::.: :::.: :
CCDS31 LRDPP--RRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLF--SPLSSSPTPM
400 410 420 430 440 450
470
pF1KE4 VTDRK
CCDS31 TICRPKGGSGDTLAPQ
460
>>CCDS1571.1 TRIM17 gene_id:51127|Hs108|chr1 (477 aa)
initn: 987 init1: 452 opt: 774 Z-score: 572.0 bits: 115.2 E(32554): 1.5e-25
Smith-Waterman score: 1023; 39.0% identity (63.7% similar) in 490 aa overlap (3-471:7-472)
10 20 30 40
pF1KE4 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNW--APGG-------GPF
:. .::: :: :::::: ::: :::::::.:.. .: : : : :
CCDS15 MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 PCPECRHPSAPAALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCL
::::::. : : :: :....: .:.. : :: .: :::.:::. :: :.:.
CCDS15 PCPECREMSPQRNLLPNRLLTKVAEMAQQHP-GLQKQDLCQEHHEPLKLFCQKDQSPICV
70 80 90 100 110
110 120 130 140 150 160
pF1KE4 VCRESQEHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIK
:::::.::. : . : .:: ..:. :: .... : .. .. .:: : .. ..:. :.:
CCDS15 VCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 SQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEV
.: :: :: :.. .:::::. .:: :. ::::: ..: :.. :.. ::. :.:..
CCDS15 ERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQL
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 GEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEA--VKVKTVCQIPLMKEMLKRFQVAVNL
:.: :..::. :: :.:.. .:. : .. .:::..: . :.:. : :
CCDS15 EERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVP
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE4 AEDTAHPKLVF--SQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCV
.:.: :.. :.. ::. .. .:. : : .:: ::.
CCDS15 DATSAYPYLLLYESRQRRYLGSSPEGSG---FCSK----------------DRFVAYPCA
300 310 320 330 340
350 360 370 380 390 400
pF1KE4 LGKNVFTSGKHYWEVE---SRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGY
.:...:.::.::::: . :.: :.::::..: . :: :. :.:.. : :
CCDS15 VGQTAFSSGRHYWEVGMNITGDALW-ALGVCRDNV-SRKDRVPKCPENGFWVVQLSK-GT
350 360 370 380 390
410 420 430 440 450
pF1KE4 WPLIGFPG-TPTQ-QEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSV-SRLRPFF
: : . ::.. .:: : .:..:: .:.:::::. :: ::::.: .. . :.:::
CCDS15 KYLSTFSALTPVMLMEPPSH-MGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFF
400 410 420 430 440 450
460 470
pF1KE4 WLSPLAS--LVIPPVTDRK
:. : .:: ::
CCDS15 CLGAPKSGQMVISTVTMWVKG
460 470
>>CCDS34375.1 TRIM10 gene_id:10107|Hs108|chr6 (481 aa)
initn: 730 init1: 330 opt: 748 Z-score: 553.3 bits: 111.8 E(32554): 1.7e-24
Smith-Waterman score: 765; 31.5% identity (60.2% similar) in 483 aa overlap (6-459:10-470)
10 20 30 40 50
pF1KE4 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGP----FP-CPE
. .:..:::: ...::.:.:::::::.:: : . :: : ::
CCDS34 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTR-YCEIPGPDLEESPTCPL
10 20 30 40 50
60 70 80 90 100
pF1KE4 CRHPSAPAALRPNWALARLTEKTQRRRL----GPVPPGLCGRHWEPLRLFCEDDQRPVCL
:..: :...:::: :: ..:. .: .: : .: .: : . .:::::. .:.
CCDS34 CKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCV
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE4 VCRESQEHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIK
::::. :: ::.: ...: :::.. : . : . ......:. : : ...
CCDS34 VCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 SQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEV
..:... .::..:..:: :.....: .:.... . .. .: : . : .. :: :.
CCDS34 TKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEEL
180 190 200 210 220 230
230 240 250 260 270
pF1KE4 GEKSQAPTLELLQNPKEVLTRSEI----QDVNYSLE-AVKVKTVCQ--IPLMKEM---LK
::.. :. ::: . . .: : : . : : : . ... : .::..:: :.
CCDS34 EEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLE
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE4 R--FQVA-----VNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQK
. :.. ..: .:.::::..:.. . .. :: :. . :::
CCDS34 KLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQ----------FSYKWQ--NSPDNPQ-
300 310 320 330 340
340 350 360 370 380
pF1KE4 TAFVERFQHLPCVLGKNVFTSGKHYW--EVESRDSLEVAVGVCREDVMGITDRSKMSPDV
::.. :::... .:.:.: : .. . .::: :::. . .. :.
CCDS34 -----RFDRATCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQR-KGELRLRPEE
350 360 370 380 390 400
390 400 410 420 430 440
pF1KE4 GIWAIYWSAAGYWPLIG-FPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSC
:.::. : :. .: :: : .: ..: : :: .: :.: .:: ..::.
CCDS34 GVWAVRL-AWGFVSALGSFPTRLTLKEQP-RQVRVSLDYEVGWVTFTNAVTREPIYTFTA
410 420 430 440 450
450 460 470
pF1KE4 SSVSRLRPFFWLSPLASLVIPPVTDRK
: . .. ::: :
CCDS34 SFTRKVIPFFGLWGRGSSFSLSS
460 470 480
>>CCDS44327.1 TRIM17 gene_id:51127|Hs108|chr1 (343 aa)
initn: 724 init1: 452 opt: 745 Z-score: 553.0 bits: 111.2 E(32554): 1.8e-24
Smith-Waterman score: 745; 41.7% identity (67.7% similar) in 288 aa overlap (3-279:7-293)
10 20 30 40
pF1KE4 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNW--APGG-------GPF
:. .::: :: :::::: ::: :::::::.:.. .: : : : :
CCDS44 MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 PCPECRHPSAPAALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCL
::::::. : : :: :....: .:.. : :: .: :::.:::. :: :.:.
CCDS44 PCPECREMSPQRNLLPNRLLTKVAEMAQQHP-GLQKQDLCQEHHEPLKLFCQKDQSPICV
70 80 90 100 110
110 120 130 140 150 160
pF1KE4 VCRESQEHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIK
:::::.::. : . : .:: ..:. :: .... : .. .. .:: : .. ..:. :.:
CCDS44 VCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 SQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEV
.: :: :: :.. .:::::. .:: :. ::::: ..: :.. :.. ::. :.:..
CCDS44 ERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQL
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 GEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEA--VKVKTVCQIPLMKEMLKRFQVAVNL
:.: :..::. :: :.:.. .:. : .. .:::..: . :.:. :
CCDS44 EERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLGKWAP
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE4 AEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLG
CCDS44 RARTSDPGSLGDAPLYPLASEATNGGGSTSALPGDGHWLFTVPS
300 310 320 330 340
>>CCDS1636.1 TRIM58 gene_id:25893|Hs108|chr1 (486 aa)
initn: 1054 init1: 354 opt: 741 Z-score: 548.3 bits: 110.8 E(32554): 3.2e-24
Smith-Waterman score: 1039; 35.8% identity (66.5% similar) in 477 aa overlap (4-471:8-462)
10 20 30 40 50
pF1KE4 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCL----HRNWAPGGGPFPCPEC
: ..:. ::.:::..:.:::..:::.:: :. ... . :: . ::.:
CCDS16 MAWAPPGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 RHPSAPAALRPNWALARLTEKTQRRRLGPVPPGL--CGRHWEPLRLFCEDDQRPVCLVCR
: : :...::: :: :.:...: :: . :: :.:: : : :::.:. .: ::
CCDS16 RGPFRPSGFRPNRQLAGLVESVRRLGLG-AGPGARRCARHGEDLSRFCEEDEAALCWVCD
70 80 90 100 110
120 130 140 150 160
pF1KE4 ESQEHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEV-KNATQWKDKIKSQ
. ::.:: ::..:: ::. :: . . . ... .. :...: :... ::.:.. :
CCDS16 AGPEHRTHRTAPLQEAAGSYQVKLQMALELMRKELEDAL-TQEANVGKKTVIWKEKVEMQ
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 RMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGE
:.:. :: : ..::..::. :.::. ::. : ..: :. .: : .::.: :. :
CCDS16 RQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 KSQAPTLELLQNPKEVLTRSE-IQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAED
. : :.: ::.. . ::.::. . .. ...::.: :: .:.:..::: :.:
CCDS16 RCQRPALGLLEGVRGVLSRSKAVTRLEAENIPMELKTACCIPGRRELLRKFQVDVKLDPA
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE4 TAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRN-PQKTAFVERFQHLPCVLGKN
::::.:... . : :.. : ::. :.. :::. ::.:: .
CCDS16 TAHPSLLLTADLRSVQDGE-----P-----------WRDVPNNP---ERFDTWPCILGLQ
300 310 320 330
350 360 370 380 390 400
pF1KE4 VFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFP
:.::.::::: .. : ..::: .:.. .. ::. :.::.. .. . ... :
CCDS16 SFSSGRHYWEVLVGEGAEWGLGVC-QDTLPRKGETTPSPENGVWALWLLKGNEYMVLASP
340 350 360 370 380 390
410 420 430 440 450 460
pF1KE4 GTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFWLSPLASLVI
..: : . . .:..:: .:..:::...:: ...::. . :::.:.. . :..
CCDS16 SVPLLQLESPRCIGIFLDYEAGEISFYNVTDGSYIYTFNQLFSGLLRPYFFICDATPLIL
400 410 420 430 440 450
470
pF1KE4 PPVTDRK
::.:
CCDS16 PPTTIAGSGNWASRDHLDPASDVRDDHL
460 470 480
>>CCDS44525.1 TRIM21 gene_id:6737|Hs108|chr11 (475 aa)
initn: 877 init1: 382 opt: 723 Z-score: 535.5 bits: 108.5 E(32554): 1.7e-23
Smith-Waterman score: 938; 38.1% identity (62.8% similar) in 465 aa overlap (6-461:10-448)
10 20 30 40 50
pF1KE4 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPS
. ::.::::::: : .::::::::.::. :. . . ::: :: ::.
CCDS44 MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQV-GKGGGSV-CPVCRQRF
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 APAALRPNWALAR----LTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRES
:::: :: : : .:. : : . :. : : :.:::: : . .: :: .:
CCDS44 LLKNLRPNRQLANMVNNLKEISQEAREG-TQGERCAVHGERLHLFCEKDGKALCWVCAQS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 QEHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQ-DVEVKNATQWKDKIKSQRM
..:. :::.:..:: . :.::: . .: :.. . .:. .. .: : .:: ...:.
CCDS44 RKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRA-DWKKTVETQKS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 RISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKS
:: .:: . .:::::::. ::.:.:.:.: . :.:. :: : .:..:: :. ..
CCDS44 RIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRC
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 QAPTLELLQNPKEVLTRSEIQDV-NYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTA
.. .:::::. :: ::: .. . .. . ....::..: .:.::. : ..: :::
CCDS44 HSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 HPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFT
.: :..:.. : :. . .: : : . :::. : ::: . :
CCDS44 NPWLILSEDRRQVRLGDTQQSIP----------GNE--------ERFDSYPMVLGAQHFH
300 310 320 330
360 370 380 390 400
pF1KE4 SGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY-WSAAGYWPLIGFPGT
::::::::. . .::::..: . .: :.:.:. :. : .: :
CCDS44 SGKHYWEVDVTGKEAWDLGVCRDSVRR-KGHFLLSSKSGFWTIWLWNKQKYEAGT-YPQT
340 350 360 370 380 390
410 420 430 440 450 460
pF1KE4 PTQQEPALHRVGVYLDRGTGNVSFYSAVD-GVHLHTFS-CSSVSRLRPFFWLSPLASLVI
: . . .::..:: .: ::::. .: : ...:: :. .. ::::: ::
CCDS44 PLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFF--SPGFNDGG
400 410 420 430 440 450
470
pF1KE4 PPVTDRK
CCDS44 KNTAPLTLCPLNIGSQGSTDY
460 470
>>CCDS31356.1 TRIM68 gene_id:55128|Hs108|chr11 (485 aa)
initn: 765 init1: 211 opt: 693 Z-score: 513.9 bits: 104.5 E(32554): 2.6e-22
Smith-Waterman score: 859; 32.3% identity (60.6% similar) in 492 aa overlap (4-465:8-468)
10 20 30 40 50
pF1KE4 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWA-PGGGP---FPCPEC
: : ::..::::. ....:.::.:::.::..:: : :: . . :: :
CCDS31 MDPTALVEAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLC
10 20 30 40 50 60
60 70 80 90 100
pF1KE4 RHPSAPAALRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVC
: : : ::::: :: ..::.. :: : . :: :: : :..::..: .: .:
CCDS31 RAPVQPRNLRPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEAC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 RESQEHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQ
.: ::..:...:.... :. .: .. ..: ..... .:. : : .. :: .....
CCDS31 SQSPEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETR
130 140 150 160 170 180
170 180 190 200 210
pF1KE4 RMRISTEFSKLHNFLVEEEDLFLQ----------RLNKEEEETKKKLNENTLKLNQTIAS
.. : :: : . .: ... : :..: :: .::. : .: :
CCDS31 KQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE4 LKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLE-AVKVKTVCQIPLMKEMLKR
: ..: :. :.:: :. .::. .:::.::. ... ....:: :.. ..:.::
CCDS31 LWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLGLREILKT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE4 FQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQ
. . : : :::. .:. :.. . :. . .. : :: :::
CCDS31 YAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLP------------DNP------ERFY
310 320 330 340
340 350 360 370 380 390
pF1KE4 HLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSK---MSPDVGIWAI--
. :::.. ..::.:::::: : : ..:::...: ::.. .:: :.:.:
CCDS31 RYNIVLGSQCISSGRHYWEVEVGDRSEWGLGVCKQNV----DRKEVVYLSPHYGFWVIRL
350 360 370 380 390
400 410 420 430 440
pF1KE4 -----YWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVD-GVHLHTFSC
: ... .:....: : .:::...: . ..:::...: : :. ::
CCDS31 RKGNEYRAGTDEYPILSLPVPP-------RRVGIFVDYEAHDISFYNVTDCGSHIFTFPR
400 410 420 430 440 450
450 460 470
pF1KE4 SSV-SRLRPFFWLSPLASLVIPPVTDRK
.:: :.: :: :.
CCDS31 YPFPGRLLPYF--SPCYSIGTNNTAPLAICSLDGED
460 470 480
474 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:13:44 2016 done: Mon Nov 7 16:13:45 2016
Total Scan time: 3.380 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]