Result of FASTA (ccds) for
pFN21AE4114
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4114, 487 aa
1>>>pF1KE4114 487 - 487 aa - 487 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3354+/-0.000809; mu= 14.8883+/- 0.049
mean_var=154.6763+/-32.589, 0's: 0 Z-trim(112.9): 165 B-trim: 0 in 0/53
Lambda= 0.103125
statistics sampled from 13330 (13562) to 13330 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.764), E-opt: 0.2 (0.417), width: 16
Scan time: 3.110
The best scores are: opt bits E(32554)
CCDS34654.1 TRIM50 gene_id:135892|Hs108|chr7 ( 487) 3393 516.7 2.2e-146
CCDS34665.1 TRIM73 gene_id:375593|Hs108|chr7 ( 250) 1578 246.3 2.8e-65
CCDS5545.1 TRIM74 gene_id:378108|Hs108|chr7 ( 250) 1568 244.9 7.8e-65
CCDS32437.1 TRIM72 gene_id:493829|Hs108|chr16 ( 477) 972 156.5 5.8e-38
CCDS34378.1 TRIM39 gene_id:56658|Hs108|chr6 ( 488) 812 132.7 8.7e-31
CCDS376.1 TRIM62 gene_id:55223|Hs108|chr1 ( 475) 779 127.8 2.6e-29
CCDS32220.1 TRIM69 gene_id:140691|Hs108|chr15 ( 500) 759 124.8 2.1e-28
CCDS1636.1 TRIM58 gene_id:25893|Hs108|chr1 ( 486) 615 103.4 5.8e-22
CCDS3808.1 TRIM60 gene_id:166655|Hs108|chr4 ( 471) 612 102.9 7.7e-22
CCDS6056.2 TRIM35 gene_id:23087|Hs108|chr8 ( 493) 596 100.6 4.1e-21
CCDS4568.1 TRIM38 gene_id:10475|Hs108|chr6 ( 465) 581 98.3 1.9e-20
CCDS4462.1 TRIM7 gene_id:81786|Hs108|chr5 ( 511) 564 95.8 1.1e-19
CCDS31356.1 TRIM68 gene_id:55128|Hs108|chr11 ( 485) 558 94.9 2.1e-19
CCDS81297.1 TRIM62 gene_id:55223|Hs108|chr1 ( 354) 548 93.3 4.7e-19
CCDS10114.1 TRIM69 gene_id:140691|Hs108|chr15 ( 341) 538 91.8 1.3e-18
CCDS78121.1 RPP21 gene_id:202658|Hs108|chr6 ( 503) 536 91.7 2e-18
CCDS73719.1 TRIM69 gene_id:140691|Hs108|chr15 ( 296) 530 90.5 2.7e-18
CCDS44525.1 TRIM21 gene_id:6737|Hs108|chr11 ( 475) 518 89.0 1.3e-17
CCDS76745.1 TRIM69 gene_id:140691|Hs108|chr15 ( 263) 504 86.6 3.6e-17
CCDS76746.1 TRIM69 gene_id:140691|Hs108|chr15 ( 279) 504 86.6 3.7e-17
CCDS3851.1 TRIML1 gene_id:339976|Hs108|chr4 ( 468) 498 86.0 9.8e-17
CCDS31048.1 TRIM11 gene_id:81559|Hs108|chr1 ( 468) 497 85.8 1.1e-16
CCDS4466.1 TRIM41 gene_id:90933|Hs108|chr5 ( 630) 481 83.6 6.8e-16
CCDS4677.1 TRIM15 gene_id:89870|Hs108|chr6 ( 465) 479 83.1 6.9e-16
CCDS31393.1 TRIM5 gene_id:85363|Hs108|chr11 ( 493) 467 81.4 2.5e-15
CCDS34375.1 TRIM10 gene_id:10107|Hs108|chr6 ( 481) 460 80.3 5e-15
CCDS4463.1 TRIM7 gene_id:81786|Hs108|chr5 ( 303) 455 79.4 6.2e-15
CCDS43414.1 TRIM7 gene_id:81786|Hs108|chr5 ( 329) 455 79.4 6.5e-15
CCDS34377.1 TRIM39 gene_id:56658|Hs108|chr6 ( 518) 457 79.9 7.2e-15
CCDS53693.1 TRIM64B gene_id:642446|Hs108|chr11 ( 449) 450 78.8 1.3e-14
CCDS475.1 ERMAP gene_id:114625|Hs108|chr1 ( 475) 450 78.8 1.4e-14
CCDS73363.1 TRIM64 gene_id:120146|Hs108|chr11 ( 449) 443 77.8 2.8e-14
CCDS1571.1 TRIM17 gene_id:51127|Hs108|chr1 ( 477) 442 77.7 3.2e-14
CCDS73287.1 TRIM64C gene_id:646754|Hs108|chr11 ( 450) 438 77.0 4.6e-14
CCDS4465.1 TRIM41 gene_id:90933|Hs108|chr5 ( 518) 433 76.4 8.5e-14
CCDS4612.2 BTN3A3 gene_id:10384|Hs108|chr6 ( 535) 424 75.0 2.2e-13
CCDS4611.1 BTN3A3 gene_id:10384|Hs108|chr6 ( 584) 424 75.1 2.3e-13
CCDS47388.1 BTN3A1 gene_id:11119|Hs108|chr6 ( 461) 422 74.7 2.4e-13
CCDS4608.1 BTN3A1 gene_id:11119|Hs108|chr6 ( 513) 422 74.7 2.6e-13
CCDS4614.1 BTN1A1 gene_id:696|Hs108|chr6 ( 526) 421 74.6 3e-13
CCDS4460.2 BTNL9 gene_id:153579|Hs108|chr5 ( 535) 412 73.2 7.6e-13
CCDS60930.1 TRIM49D1 gene_id:399939|Hs108|chr11 ( 452) 399 71.2 2.6e-12
CCDS4654.1 TRIM27 gene_id:5987|Hs108|chr6 ( 513) 398 71.1 3.1e-12
CCDS5678.1 TRIM4 gene_id:89122|Hs108|chr7 ( 474) 387 69.5 9.2e-12
CCDS10498.1 MEFV gene_id:4210|Hs108|chr16 ( 781) 388 69.9 1.2e-11
CCDS55762.1 TRIM49B gene_id:283116|Hs108|chr11 ( 452) 377 68.0 2.5e-11
CCDS31392.1 TRIM5 gene_id:85363|Hs108|chr11 ( 326) 374 67.3 2.8e-11
CCDS31394.1 TRIM5 gene_id:85363|Hs108|chr11 ( 347) 374 67.4 2.9e-11
CCDS13904.1 RFPL3 gene_id:10738|Hs108|chr22 ( 288) 368 66.4 4.7e-11
CCDS43011.1 RFPL3 gene_id:10738|Hs108|chr22 ( 317) 368 66.4 5e-11
>>CCDS34654.1 TRIM50 gene_id:135892|Hs108|chr7 (487 aa)
initn: 3393 init1: 3393 opt: 3393 Z-score: 2741.5 bits: 516.7 E(32554): 2.2e-146
Smith-Waterman score: 3393; 100.0% identity (100.0% similar) in 487 aa overlap (1-487:1-487)
10 20 30 40 50 60
pF1KE4 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DGSSSLPNVSLARVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 DGSSSLPNVSLARVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 ELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHKF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 IRKFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPEPLKLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 IRKFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPEPLKLDP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 ATAHPLLELSKGNTVVQCGLLAQRRASQPERFDYSTCVLASRGFSCGRHYWEVVVGSKSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 ATAHPLLELSKGNTVVQCGLLAQRRASQPERFDYSTCVLASRGFSCGRHYWEVVVGSKSD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 WRLGVIKGTASRKGKLNRSPEHGVWLIGLKEGRVYEAFACPRVPLPVAGHPHRIGLYLHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 WRLGVIKGTASRKGKLNRSPEHGVWLIGLKEGRVYEAFACPRVPLPVAGHPHRIGLYLHY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 EQGELTFFDADRPDDLRPLYTFQADFQGKLYPILDTCWHERGSNSLPMVLPPPSGPGPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 EQGELTFFDADRPDDLRPLYTFQADFQGKLYPILDTCWHERGSNSLPMVLPPPSGPGPLS
430 440 450 460 470 480
pF1KE4 PEQPTKL
:::::::
CCDS34 PEQPTKL
>>CCDS34665.1 TRIM73 gene_id:375593|Hs108|chr7 (250 aa)
initn: 1578 init1: 1578 opt: 1578 Z-score: 1285.5 bits: 246.3 E(32554): 2.8e-65
Smith-Waterman score: 1578; 93.2% identity (96.8% similar) in 250 aa overlap (1-250:1-250)
10 20 30 40 50 60
pF1KE4 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAV
::::::: ::::::::::::::::: :::::::::::::::::: :::...:::.: :.:
CCDS34 MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DGSSSLPNVSLARVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQ
:::::::: ::::::::::.::::::::::::::::::.:::::::::::::::::::::
CCDS34 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 ELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHKF
::.: :::::::::::::::::::::::::::::::::::::::::::::::::::::.:
CCDS34 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 IRKFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPEPLKLDP
: ::::::::
CCDS34 IWKFHSMASR
250
>>CCDS5545.1 TRIM74 gene_id:378108|Hs108|chr7 (250 aa)
initn: 1568 init1: 1568 opt: 1568 Z-score: 1277.5 bits: 244.9 E(32554): 7.8e-65
Smith-Waterman score: 1568; 92.8% identity (96.4% similar) in 250 aa overlap (1-250:1-250)
10 20 30 40 50 60
pF1KE4 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAV
::::::: :::: :::::::::::: :::::::::::::::::: :::...:::.: :.:
CCDS55 MAWQVSLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DGSSSLPNVSLARVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQ
:::::::: ::::::::::.::::::::::::::::::.:::::::::::::::::::::
CCDS55 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 ELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHKF
::.: :::::::::::::::::::::::::::::::::::::::::::::::::::::.:
CCDS55 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 IRKFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPEPLKLDP
: ::::::::
CCDS55 IWKFHSMASR
250
>>CCDS32437.1 TRIM72 gene_id:493829|Hs108|chr16 (477 aa)
initn: 904 init1: 255 opt: 972 Z-score: 795.0 bits: 156.5 E(32554): 5.8e-38
Smith-Waterman score: 972; 33.8% identity (63.7% similar) in 479 aa overlap (10-475:8-474)
10 20 30 40 50
pF1KE4 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCL--VSLSCHLDAELRCPVCRQ
:...:.::.::..: :. .::::.:..:: :. :. . :: :.
CCDS32 MSAAPGLLHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQA
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 AVDGSSSLPNVSLARVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQ
. .. :..:::..:.: :. . : .: .:::..::.:. :.::.:. ::::.
CCDS32 PTRPQALSTNLQLARLVEGLAQV--PQGH-CEEHLDPLSIYCEQDRALVCGVCASLGSHR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 HHPVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVI---
: . :.. ...:.: .: .:.. . .. .: : .. ... . : ..
CCDS32 GHRLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 ----RREFQELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQ
: . :. .:.: : : : ..::. ::: : : : :::.
CCDS32 LGKMRVFLAALEGSLDREAERVRGEAGVALRRELGSLNSYLEQ-------LRQMEKVLEE
180 190 200 210 220
240 250 260 270 280 290
pF1KE4 FGNEDHHKFIRKFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLP
... . .:. :. ..:: . :. : :.. : . . :.:. ::...:: ..:
CCDS32 VADKPQTEFLMKYCLVTSRLQKILAESPPPARLDIQL-PIISD-DFKFQVWRKMFRALMP
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE4 APEPLKLDPATAHPLLELSKGNTVVQCGLLAQRRASQ-PERFDYSTCVLASRGFSCGRHY
: : : .::..::: : .:... :.:. :.. :..:: .. :.: . .: :.::
CCDS32 ALEELTFDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHY
290 300 310 320 330 340
360 370 380 390 400
pF1KE4 WEVVVGSKSDWRLGVIKGTASRKGKLNRSPEHGVWLIGLKEGRVYEAFACPRVPLPVAG-
::: ::.: : :::: . : :.:.:. : .:.::.::.::.. :: . . : . .
CCDS32 WEVDVGDKPRWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSP
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE4 --HPHRIGLYLHYEQGELTFFDADRPDDLRPLYTFQADFQGKLYPILDTCWHERGSNSLP
.: :::::: . .: :.:.::. : : ::..:. . .::..:.:::..:.:. :
CCDS32 ERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCWHDKGKNAQP
410 420 430 440 450 460
470 480
pF1KE4 MVLPPPSGPGPLSPEQPTKL
..: : :
CCDS32 LLLVGPEGAEA
470
>>CCDS34378.1 TRIM39 gene_id:56658|Hs108|chr6 (488 aa)
initn: 773 init1: 340 opt: 812 Z-score: 666.2 bits: 132.7 E(32554): 8.7e-31
Smith-Waterman score: 812; 29.3% identity (59.6% similar) in 475 aa overlap (6-474:19-485)
10 20 30 40
pF1KE4 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHL
.: .:. . .: .::: .:::....:::..::.:.. :
CCDS34 MAETSLLEAGASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 DAELRCPVCRQAVDGSSSLPNVSLARVIEALRLPGDPEPKV-----CVHHRNPLSLFCEK
. .. :::::.. : :: .:. ..: . . :. : .:.. ::::: .
CCDS34 ERDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 DQELICGLCGLLGSHQHHPVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRT
::: .: .:.. .:. : :.:.. . ...::.: . :.:. ... . .. ..
CCDS34 DQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPG
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 RIVNESDVFSWVIRREFQELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERL
.. . : :::.:::. .:::. : . . . .. : . . :. :
CCDS34 ELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE4 AQAECVLEQFGNEDHHKFIRKFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVW
:. .: .. .... .: . : ... .: . : .. .. . . .
CCDS34 AHLAAEVEGKCLQSGFEMLKDVKSTLEKCE--KVKTMEVTSVSIELEKNFSNFPRQYFAL
250 260 270 280 290
290 300 310 320 330 340
pF1KE4 KRLFRKVLPAPEPLKLDPATAHPLLELSKGNTVVQCGLLAQRR-ASQPERFDYSTCVLAS
........ . ::: :::: : ::. :. : . :.:: . ::::.
CCDS34 RKILKQLI---ADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLAT
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE4 RGFSCGRHYWEVVVGSKSDWRLGVIKGTASRKGKLNRSPEHGVWLIGLKEGRVYEAFACP
.::. ::::::: ::.:. : .:: . ..::::.:. :: : : . : .: : : . :
CCDS34 EGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTP
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE4 RVPLPVAGHPHRIGLYLHYEQGELTFFDADRPDDLRPLYTFQADFQGKLYPILDTCWHER
.:: . .:.:.:..: :: : :.:... : .::: : ::.:.. .
CCDS34 FTPLHIKVKPKRVGIFLDYEAGTLSFYNVT---DRSHIYTFTDTFTEKLWPLFYPGIRAG
420 430 440 450 460 470
470 480
pF1KE4 GSNSLPMVLPPPSGPGPLSPEQPTKL
.:. :... ::.
CCDS34 RKNAAPLTIRPPTDWE
480
>>CCDS376.1 TRIM62 gene_id:55223|Hs108|chr1 (475 aa)
initn: 653 init1: 286 opt: 779 Z-score: 639.8 bits: 127.8 E(32554): 2.6e-29
Smith-Waterman score: 779; 30.1% identity (60.9% similar) in 471 aa overlap (10-468:5-468)
10 20 30 40 50
pF1KE4 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAE-LR-CPVCRQ
:.:.: : ::: ....:. : : : .:. :.. . .:. : :: ::.
CCDS37 MACSLKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRR
10 20 30 40 50
60 70 80 90 100 110
pF1KE4 AVDGSSSLPNVSLARVIEALR-LPGDP------EPKVCVHHRNPLSLFCEKDQELICGLC
. . :...:: ..: .: : . : : . ..::: :. :.: .:
CCDS37 TFAEPALAPSLKLANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 GLLGSHQHHPVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVF
. :..: :: .. .......:: .. :.. ... : . : . .. . . .
CCDS37 DEPALHEQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 SWVIRREFQELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQ-AQGTRERLAQAECVLE
.: . :..::.:. :.. :: . . : .......... .: :. :. . :
CCDS37 RTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 QFGNEDHHKFIRKFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVL
.... :.: :. ..:: .: ... : .. .: . . . .. :.:: ::. .
CCDS37 RLAETDRHTFLA---GVASLSERLKGKIHETNLTYEDFPTSKYTGPLQYTIWKSLFQDIH
240 250 260 270 280 290
300 310 320 330 340
pF1KE4 PAPEPLKLDPATAHPLLELSKGNTVVQCG-LLAQRRASQPERFDYSTCVLASRGFSCGRH
:.: : :::.::: : :: :.: : : : ..:.::: . ::.:..:: : :
CCDS37 PVPAALTLDPGTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVH
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE4 YWEVVVGSKSDWRLGVIKGTASRKGKLNRSPEHGVWLIGLKEGRVYEAFACPRVPLPVAG
::::::. :..: .:. . .:::::... .: .: . : ...: : : . : . : :
CCDS37 YWEVVVAEKTQWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRD
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE4 HPHRIGLYLHYEQGELTFFDADRPDDLRPLYTFQADFQGKLYPILDTCW-HERGSNSLPM
. ..:..: :.:: : :..:: :. ::::. : ::: .. : :.: :.
CCDS37 KLDKVGVFLDYDQGLLIFYNAD---DMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPL
420 430 440 450 460
470 480
pF1KE4 VLPPPSGPGPLSPEQPTKL
CCDS37 RINTVRI
470
>>CCDS32220.1 TRIM69 gene_id:140691|Hs108|chr15 (500 aa)
initn: 667 init1: 415 opt: 759 Z-score: 623.5 bits: 124.8 E(32554): 2.1e-28
Smith-Waterman score: 759; 30.6% identity (59.1% similar) in 484 aa overlap (4-472:29-499)
10 20 30
pF1KE4 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSY
.: . .. .:.::.: . :..::::.:::..
CCDS32 MEVSTNPSSNIDPGDYVEMNDSITHLPSKVVIQDITMELHCPLCNDWFRDPLMLSCGHNF
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE4 CKGCLVSLSCHLDAELRCPVCRQAVDGSSSLPNVSLARVIEALR-LP---GDPEPKVCVH
:..:. .. : :: :.. . .. : : ...: .. :: : :. : .
CCDS32 CEACIQDFWRLQAKETFCPECKMLCQYNNCTFNPVLDKLVEKIKKLPLLKGHPQ---CPE
70 80 90 100 110
100 110 120 130 140
pF1KE4 HRNPLSLFCEKDQELICGLC--GLLGSHQHHPVTPVSTVYSRMKEELAALISELKQEQKK
: . :.:: . : .::: : . :. : . .: . . :::: ..:. :.
CCDS32 HGENLKLFSKPDGKLICFQCKDARLSVGQSKEFLQISDAVHFFTEELAIQQGQLETTLKE
120 130 140 150 160 170
150 160 170 180 190 200
pF1KE4 VDELIAKLVNNRTRIVNESDV-FSWVIRREFQELHHLVDEEKARCLEGIGGHTRGLVASL
.. : .. .. .:. . .. . :: .::... .. : . . ..: .
CCDS32 LQTL-RNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEM
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE4 DMQLEQAQG----TRERLAQAECVLEQFGNEDHHKFIRKF-HSMASRAEMPQARPLEGAF
...: : : ... :.. . :: .. : : : . ::. . .. .: :
CCDS32 ELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATREL----
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE4 SPISFKPGLHQ--ADIKLTVWKRLFRKVLPAPEPLKLDPATAHPLLELSKGNTVVQCGLL
:: : .: : . :. ::... . :. :: ::: :::: : :::..: : : .
CCDS32 --ISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDI
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE4 AQRRASQPERFDYSTCVLASRGFSCGRHYWEVVVGSKSDWRLGVIKGTASRKGKLNRSPE
. ..::::: :. ::.::::. :. :::: :..:. : .::.. . :::. .::
CCDS32 KKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPE
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE4 HGVWLIGLKEGRVYEAFACPRVPLPVAGHPHRIGLYLHYEQGELTFFDADRPDDLRPLYT
.: ::. :.. .:. : : .... ..:.:: :: :.:.:..: . .::
CCDS32 QGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAK---TMTHIYT
420 430 440 450 460
450 460 470 480
pF1KE4 FQADFQGKLYPILDTCWHERGSNSLPM-VLPPPSGPGPLSPEQPTKL
:. :. :::: . : .. : :. :. .: :
CCDS32 FSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ
470 480 490 500
>>CCDS1636.1 TRIM58 gene_id:25893|Hs108|chr1 (486 aa)
initn: 680 init1: 404 opt: 615 Z-score: 507.8 bits: 103.4 E(32554): 5.8e-22
Smith-Waterman score: 766; 31.0% identity (57.4% similar) in 491 aa overlap (1-477:1-465)
10 20 30 40 50
pF1KE4 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAE----LRCPVC
::: .:.. .::.::. ..::. ..::::.: :. . . :. :: :
CCDS16 MAWAPPGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 RQAVDGSSSLPNVSLARVIEALR---LPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGL
: :. :: .:: ..:..: : . : . :..: . :: :::.:. .: .:
CCDS16 RGPFRPSGFRPNRQLAGLVESVRRLGLGAGPGARRCARHGEDLSRFCEEDEAALCWVCDA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 LGSHQHHPVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKL-VNNRTRIVNES-DVF
:. : ..:.. . . .. .: . ...: . : : . :...: : .:. ..
CCDS16 GPEHRTHRTAPLQEAAGSYQVKLQMALELMRKELE--DALTQEANVGKKTVIWKEKVEMQ
130 140 150 160 170
180 190 200 210 220 230
pF1KE4 SWVIRREFQELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQ
.: ::.. . .. .:. : : : : : :.. . .. ::.: .:..
CCDS16 RQRFRLEFEKHRGFLAQEEQRQL-------RRLEAEERATLQRLRESKSRLVQQSKALKE
180 190 200 210 220 230
240 250 260 270 280
pF1KE4 FGNEDHHKFIRKFHSM--ASRAEMPQARP---LEGAFSPISFKPGLHQADIKLTVWKRLF
...: ... : .. . :. . ... ::. :. .: . . ..:.
CCDS16 LADELQERCQRPALGLLEGVRGVLSRSKAVTRLEAENIPMELKTACC-----IPGRRELL
240 250 260 270 280
290 300 310 320 330 340
pF1KE4 RKVLPAPEPLKLDPATAHPLLELSKGNTVVQCGLLAQRRASQPERFDYSTCVLASRGFSC
:: .::::::::: : :. :: : . ..::::: :.:. ..::
CCDS16 RKF---QVDVKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSS
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE4 GRHYWEVVVGSKSDWRLGVIKGTASRKGKLNRSPEHGVWLIGLKEGRVYEAFACPRVPLP
:::::::.:: ..: ::: . : :::. . :::.::: . : .: : ..: : :::
CCDS16 GRHYWEVLVGEGAEWGLGVCQDTLPRKGETTPSPENGVWALWLLKGNEYMVLASPSVPLL
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE4 VAGHPHRIGLYLHYEQGELTFFDADRPDDLRPLYTFQADFQGKLYPILDTCWHERGSNSL
:. ::..: :: ::..:... : .:::. :.: : : . : ..
CCDS16 QLESPRCIGIFLDYEAGEISFYNVT---DGSYIYTFNQLFSGLLRPYFFIC------DAT
410 420 430 440 450
470 480
pF1KE4 PMVLPPPSGPGPLSPEQPTKL
:..::: . :
CCDS16 PLILPPTTIAGSGNWASRDHLDPASDVRDDHL
460 470 480
>>CCDS3808.1 TRIM60 gene_id:166655|Hs108|chr4 (471 aa)
initn: 563 init1: 255 opt: 612 Z-score: 505.6 bits: 102.9 E(32554): 7.7e-22
Smith-Waterman score: 612; 28.0% identity (57.4% similar) in 479 aa overlap (1-468:1-461)
10 20 30 40 50
pF1KE4 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCR---
: . ..: .:... .:::::: .:.:. ..:::..:..:: :: . :::::
CCDS38 MEFVTALVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDTFPCPVCRFCF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 --QAVDGSSSLPNVS-LARVIEALRLPG--DPEPKVCVHHRNPLSLFCEKDQELICGLCG
.. . .: :.. .:. .. : . : .: .: . :.::: :: :..: :.
CCDS38 PYKSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 LLGSHQHHPVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFS
. .::.: . :.. . : .: : . . :... ..:...: .. ... .. .
CCDS38 FSTKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 WVIRREFQELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQF
: ::.... ....:. :. : . ...:.:. .: . :.. .:...
CCDS38 EEINSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVE-------LSDYVSTLKHL
190 200 210 220 230
240 250 260 270 280 290
pF1KE4 GNEDHHKFIRKFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTV-WKRLFRKVLP
: . : ... . ..:. . . .. : :. : . ..: .. : : . :
CCDS38 LREVEGKSVQSNLELLTQAKSMHHK-YQNLKCPELFSFRLTKYGFSLPPQYSGLDRIIKP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 APEPLKLDPATAHPLLELSKGNTVVQCGLLAQRRASQPERFDYSTCVLASRGFSCGRHYW
. :: :::: : .:. .:. . .:.:: ::.:. :: :::::
CCDS38 FQVDVILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYW
300 310 320 330 340 350
360 370 380 390 400
pF1KE4 EVVVGSKSDWRLGVIKGTASRKGKLNRSPEHGVWLIG--LKEGRVYEAFACPRVPLPVAG
:: ::.: : ::: . :. . . : : : :: .: : : . .. :::.
CCDS38 EVEVGNKPKWILGVCQDCLLRNWQDQPSVLGGFWAIGRYMKSGYVASGPKTTQL-LPVV-
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE4 HPHRIGLYLHYEQGELTFFDADRPDDLRPLYTFQADFQGKLYPILDTCWHERGSNSLPMV
.: .::..: :: :.:.:.. . : ::::. : ..: . : :..: :.
CCDS38 KPSKIGIFLDYELGDLSFYNMN---DRSILYTFNDCFTEAVWPYFYT-----GTDSEPLK
420 430 440 450 460
470 480
pF1KE4 LPPPSGPGPLSPEQPTKL
CCDS38 ICSVSDSER
470
>>CCDS6056.2 TRIM35 gene_id:23087|Hs108|chr8 (493 aa)
initn: 497 init1: 172 opt: 596 Z-score: 492.5 bits: 100.6 E(32554): 4.1e-21
Smith-Waterman score: 596; 28.2% identity (57.1% similar) in 471 aa overlap (10-452:15-462)
10 20 30 40 50
pF1KE4 MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPV
....: : .: . :.. . :.:::..:.:: :: .... :::
CCDS60 MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGC-VSRCWEVQVSPTCPV
10 20 30 40 50
60 70 80 90 100
pF1KE4 CRQAVDGSSSLPNVSLARVIEAL--------RLPGDPEPKVCVHHRNPLSLFCEKDQELI
:.. .. .. : .: ..: : : . .:: ::. ::::: .:.::.
CCDS60 CKDRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELL
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE4 CGLCGLLGSHQHHPVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNE
: : :: : : ::. . .. . . :... : . . . :...
CCDS60 CCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKA----FWAMRRSYEAIAKH
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE4 SDVFS-WV---IRREFQELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLA
..: . :. ::.::..:.... :. :.... .:: : ...: : ::
CCDS60 NQVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLA
180 190 200 210 220 230
230 240 250 260 270
pF1KE4 QAECVLEQFGNEDHHKFIRKFHSMASRAEMPQARPLEGAFSPISFKPGL------HQADI
. :.. .:: .:. : .: . : : .. : .::. . ...
CCDS60 HEIERLQMEMKEDDVSFLMKHKS--------RKRRLFCTMEPEPVQPGMLIDVCKYLGSL
240 250 260 270 280
280 290 300 310 320 330
pF1KE4 KLTVWKRLFRKVLPAPEPLKLDPATAHPLLELSKG-NTVVQCGLLAQRRASQPERFDYST
. :::... .: .: ...:: :: : .: ..:.. : .: . .::::. .
CCDS60 QYRVWKKMLASVESVP--FSFDPNTAAGWLSVSDDLTSVTNHGYRVQ--VENPERFSSAP
290 300 310 320 330 340
340 350 360 370 380 390
pF1KE4 CVLASRGFSCGRHYWEVVVGSKSDWRLGVIK-----GTASRKGKLNRSPEHGVWLIGLKE
:.:.:: :: : : :::..:. ..::.::.. :. ... . .. . : : . .
CCDS60 CLLGSRVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQ
350 360 370 380 390 400
400 410 420 430 440
pF1KE4 GRVYEAFAC----PRVPLPVAGHPHRIGLYLHYEQGELTFFDADRPDDLRPLYTFQADFQ
: :. : : . : . :.:. . :. :.:::.:.::.: ::::.: :
CCDS60 G--VEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCH---LYTFHARF-
410 420 430 440 450
450 460 470 480
pF1KE4 GKLYPILDTCWHERGSNSLPMVLPPPSGPGPLSPEQPTKL
:.. :
CCDS60 GEVRPYFYLGGARGAGPPEPLRICPLHISVKEELDG
460 470 480 490
487 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:33:12 2016 done: Mon Nov 7 16:33:12 2016
Total Scan time: 3.110 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]