Result of FASTA (omim) for
pFN21AE4110
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4110, 481 aa
1>>>pF1KE4110 481 - 481 aa - 481 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7984+/-0.000484; mu= 7.0241+/- 0.030
mean_var=204.3373+/-44.010, 0's: 0 Z-trim(116.3): 239 B-trim: 1633 in 2/52
Lambda= 0.089722
statistics sampled from 27047 (27341) to 27047 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.321), width: 16
Scan time: 10.080
The best scores are: opt bits E(85289)
NP_006769 (OMIM: 605701) tripartite motif-containi ( 481) 3287 438.6 1.8e-122
XP_011512523 (OMIM: 605701) PREDICTED: tripartite ( 499) 3156 421.7 2.4e-117
XP_011512524 (OMIM: 605701) PREDICTED: tripartite ( 499) 3156 421.7 2.4e-117
XP_011512525 (OMIM: 605701) PREDICTED: tripartite ( 499) 3156 421.7 2.4e-117
NP_439893 (OMIM: 605701) tripartite motif-containi ( 395) 2536 341.3 2.9e-93
XP_011512527 (OMIM: 605701) PREDICTED: tripartite ( 413) 2405 324.4 3.8e-88
XP_005249434 (OMIM: 600830) PREDICTED: tripartite ( 539) 905 130.3 1.3e-29
NP_003440 (OMIM: 600830) tripartite motif-containi ( 539) 905 130.3 1.3e-29
XP_005249433 (OMIM: 600830) PREDICTED: tripartite ( 539) 905 130.3 1.3e-29
XP_005249435 (OMIM: 600830) PREDICTED: tripartite ( 539) 905 130.3 1.3e-29
NP_001229712 (OMIM: 600830) tripartite motif-conta ( 539) 905 130.3 1.3e-29
XP_006715243 (OMIM: 600830) PREDICTED: tripartite ( 539) 905 130.3 1.3e-29
XP_005249432 (OMIM: 600830) PREDICTED: tripartite ( 539) 905 130.3 1.3e-29
XP_005249431 (OMIM: 600830) PREDICTED: tripartite ( 539) 905 130.3 1.3e-29
NP_060543 (OMIM: 613184) E3 ubiquitin-protein liga ( 485) 808 117.7 7.2e-26
NP_976038 (OMIM: 609315) tripartite motif-containi ( 511) 754 110.8 9.4e-24
NP_006501 (OMIM: 602165) zinc finger protein RFP [ ( 513) 746 109.7 1.9e-23
NP_742013 (OMIM: 605700) E3 ubiquitin-protein liga ( 488) 704 104.3 8.1e-22
NP_477514 (OMIM: 607564) tripartite motif-containi ( 488) 692 102.7 2.4e-21
NP_001003818 (OMIM: 607564) tripartite motif-conta ( 516) 692 102.8 2.5e-21
NP_067629 (OMIM: 605684) tripartite motif-containi ( 488) 630 94.7 6.2e-19
NP_001003827 (OMIM: 605684) tripartite motif-conta ( 488) 630 94.7 6.2e-19
NP_067076 (OMIM: 605700) E3 ubiquitin-protein liga ( 518) 618 93.2 1.9e-18
NP_291027 (OMIM: 610530) E3 ubiquitin-protein liga ( 630) 619 93.4 2e-18
XP_006714995 (OMIM: 610530) PREDICTED: E3 ubiquiti ( 520) 615 92.8 2.5e-18
XP_006714992 (OMIM: 610530) PREDICTED: E3 ubiquiti ( 543) 615 92.8 2.6e-18
NP_963921 (OMIM: 610530) E3 ubiquitin-protein liga ( 518) 613 92.5 3e-18
XP_006714994 (OMIM: 610530) PREDICTED: E3 ubiquiti ( 525) 613 92.5 3e-18
XP_006714993 (OMIM: 610530) PREDICTED: E3 ubiquiti ( 541) 613 92.5 3.1e-18
XP_011512567 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 421) 600 90.8 8.3e-18
NP_008959 (OMIM: 609316) E3 ubiquitin-protein liga ( 425) 600 90.8 8.3e-18
XP_011512566 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 424) 583 88.6 3.8e-17
NP_149023 (OMIM: 608487) tripartite motif-containi ( 493) 579 88.1 6.1e-17
XP_005253240 (OMIM: 608487) PREDICTED: tripartite ( 493) 579 88.1 6.1e-17
NP_976042 (OMIM: 609315) tripartite motif-containi ( 329) 572 87.0 8.6e-17
XP_011512568 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 261) 564 85.9 1.5e-16
NP_976040 (OMIM: 609315) tripartite motif-containi ( 303) 561 85.6 2.2e-16
NP_976041 (OMIM: 609315) tripartite motif-containi ( 303) 561 85.6 2.2e-16
XP_016865392 (OMIM: 609315) PREDICTED: tripartite ( 303) 561 85.6 2.2e-16
NP_976039 (OMIM: 609315) tripartite motif-containi ( 303) 561 85.6 2.2e-16
NP_006065 (OMIM: 606559) E3 ubiquitin-protein liga ( 498) 541 83.2 1.8e-15
XP_016873951 (OMIM: 608487) PREDICTED: tripartite ( 300) 534 82.1 2.4e-15
XP_005253241 (OMIM: 608487) PREDICTED: tripartite ( 326) 534 82.1 2.6e-15
NP_149084 (OMIM: 608487) tripartite motif-containi ( 326) 534 82.1 2.6e-15
NP_149083 (OMIM: 608487) tripartite motif-containi ( 347) 534 82.1 2.7e-15
NP_660215 (OMIM: 607868) E3 ubiquitin-protein liga ( 468) 536 82.5 2.8e-15
NP_060677 (OMIM: 616755) E3 ubiquitin-protein liga ( 475) 536 82.5 2.8e-15
NP_003132 (OMIM: 109092) E3 ubiquitin-protein liga ( 475) 534 82.3 3.3e-15
XP_016857118 (OMIM: 616755) PREDICTED: E3 ubiquiti ( 555) 533 82.2 4.1e-15
XP_011518729 (OMIM: 608487) PREDICTED: tripartite ( 271) 520 80.2 7.9e-15
>>NP_006769 (OMIM: 605701) tripartite motif-containing p (481 aa)
initn: 3287 init1: 3287 opt: 3287 Z-score: 2319.7 bits: 438.6 E(85289): 1.8e-122
Smith-Waterman score: 3287; 100.0% identity (100.0% similar) in 481 aa overlap (1-481:1-481)
10 20 30 40 50 60
pF1KE4 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 CREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 KRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 EKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALGSFPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALGSFPT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE4 RLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGLWGRGSSFSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGLWGRGSSFSLS
430 440 450 460 470 480
pF1KE4 S
:
NP_006 S
>>XP_011512523 (OMIM: 605701) PREDICTED: tripartite moti (499 aa)
initn: 3156 init1: 3156 opt: 3156 Z-score: 2227.9 bits: 421.7 E(85289): 2.4e-117
Smith-Waterman score: 3156; 100.0% identity (100.0% similar) in 461 aa overlap (21-481:39-499)
10 20 30 40 50
pF1KE4 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPD
::::::::::::::::::::::::::::::
XP_011 LHSVTQSPTCPQKNISSDSGQLTYHHFPSTGTLREPVTIDCGHNFCRACLTRYCEIPGPD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 LEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 EDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 MQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEIC
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 RFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 QREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 ATCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWG
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE4 FVSALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVSALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGL
430 440 450 460 470 480
480
pF1KE4 WGRGSSFSLSS
:::::::::::
XP_011 WGRGSSFSLSS
490
>>XP_011512524 (OMIM: 605701) PREDICTED: tripartite moti (499 aa)
initn: 3156 init1: 3156 opt: 3156 Z-score: 2227.9 bits: 421.7 E(85289): 2.4e-117
Smith-Waterman score: 3156; 100.0% identity (100.0% similar) in 461 aa overlap (21-481:39-499)
10 20 30 40 50
pF1KE4 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPD
::::::::::::::::::::::::::::::
XP_011 LHSVTQSPTCPQKNISSDSGQLTYHHFPSTGTLREPVTIDCGHNFCRACLTRYCEIPGPD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 LEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 EDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 MQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEIC
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 RFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 QREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 ATCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWG
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE4 FVSALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVSALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGL
430 440 450 460 470 480
480
pF1KE4 WGRGSSFSLSS
:::::::::::
XP_011 WGRGSSFSLSS
490
>>XP_011512525 (OMIM: 605701) PREDICTED: tripartite moti (499 aa)
initn: 3156 init1: 3156 opt: 3156 Z-score: 2227.9 bits: 421.7 E(85289): 2.4e-117
Smith-Waterman score: 3156; 100.0% identity (100.0% similar) in 461 aa overlap (21-481:39-499)
10 20 30 40 50
pF1KE4 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPD
::::::::::::::::::::::::::::::
XP_011 LHSVTQSPTCPQKNISSDSGQLTYHHFPSTGTLREPVTIDCGHNFCRACLTRYCEIPGPD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 LEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 EDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 MQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEIC
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 RFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 QREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 ATCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWG
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE4 FVSALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVSALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGL
430 440 450 460 470 480
480
pF1KE4 WGRGSSFSLSS
:::::::::::
XP_011 WGRGSSFSLSS
490
>>NP_439893 (OMIM: 605701) tripartite motif-containing p (395 aa)
initn: 2534 init1: 2534 opt: 2536 Z-score: 1795.4 bits: 341.3 E(85289): 2.9e-93
Smith-Waterman score: 2536; 97.4% identity (98.2% similar) in 379 aa overlap (1-379:1-379)
10 20 30 40 50 60
pF1KE4 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_439 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_439 KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 CREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_439 CREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 KRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_439 KRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 EKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_439 EKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 LCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_439 LCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 TGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALGSFPT
:::::::: . ..:
NP_439 TGGRHTWVWMARVPGDSGCCQFCSPPSVLGTEVAA
370 380 390
>>XP_011512527 (OMIM: 605701) PREDICTED: tripartite moti (413 aa)
initn: 2403 init1: 2403 opt: 2405 Z-score: 1703.5 bits: 324.4 E(85289): 3.8e-88
Smith-Waterman score: 2405; 97.2% identity (98.1% similar) in 359 aa overlap (21-379:39-397)
10 20 30 40 50
pF1KE4 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPD
::::::::::::::::::::::::::::::
XP_011 LHSVTQSPTCPQKNISSDSGQLTYHHFPSTGTLREPVTIDCGHNFCRACLTRYCEIPGPD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 LEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 EDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 MQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEIC
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE4 RFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE4 QREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE4 ATCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWG
:::::::::::::::::: . ..:
XP_011 ATCVLAHTGITGGRHTWVWMARVPGDSGCCQFCSPPSVLGTEVAA
370 380 390 400 410
>>XP_005249434 (OMIM: 600830) PREDICTED: tripartite moti (539 aa)
initn: 1225 init1: 549 opt: 905 Z-score: 652.7 bits: 130.3 E(85289): 1.3e-29
Smith-Waterman score: 1044; 37.0% identity (60.5% similar) in 522 aa overlap (1-458:1-516)
10 20 30 40 50 60
pF1KE4 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC
::..: . :: .::.: :: ::.:::::::: :::.: : : : :.::::
XP_005 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGS----RPVCPLC
10 20 30 40 50
70 80 90 100 110
pF1KE4 KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGE-----ED--VCQEHGEKIYFFCEDD
:.::. ..:: ::::..:::::::.. . :: .: .:..: ::....::::
XP_005 KKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 EMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQV
:::.:::. :: :: ..: :: :.::.: . :. ::..:..:: .:.. . . .
XP_005 GKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 LLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFS
: ... .:: ...:: . ..::.:.. :: :: . . .. . :..: .::. :..
XP_005 ALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 ALIEELEEKNERPARELLTDIRSTLIRCETRK--CRKPVAVSPELGQRIRDFPQQALPLQ
.: ::: : ..:: ::. : :. : : .: ::.: . .. .: .. : ::
XP_005 LVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARV--VKKKTGEFSDKLLSLQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 REMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRA
: .. : :: .:.:. . ..::::.. : :::: . . .. .... .::.::
XP_005 RGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCE
300 310 320 330 340 350
360 370
pF1KE4 TCVLAHTGITGGRHTWVVSI-------DLAHGG---------------------------
::. :.: :. : : . : .:
XP_005 PGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDE
360 370 380 390 400 410
380 390 400 410
pF1KE4 ---------------------SCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALG
:: :::. ..:.:::.: ::::.::::.::. . . :
XP_005 DEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANT
420 430 440 450 460 470
420 430 440 450 460 470
pF1KE4 SFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGLWGRGSS
: ..: .::.: ..:::: : :::::: ..: ::::::
XP_005 SPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTR
480 490 500 510 520 530
480
pF1KE4 FSLSS
XP_005 LLLRP
>>NP_003440 (OMIM: 600830) tripartite motif-containing p (539 aa)
initn: 1225 init1: 549 opt: 905 Z-score: 652.7 bits: 130.3 E(85289): 1.3e-29
Smith-Waterman score: 1044; 37.0% identity (60.5% similar) in 522 aa overlap (1-458:1-516)
10 20 30 40 50 60
pF1KE4 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC
::..: . :: .::.: :: ::.:::::::: :::.: : : : :.::::
NP_003 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGS----RPVCPLC
10 20 30 40 50
70 80 90 100 110
pF1KE4 KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGE-----ED--VCQEHGEKIYFFCEDD
:.::. ..:: ::::..:::::::.. . :: .: .:..: ::....::::
NP_003 KKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 EMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQV
:::.:::. :: :: ..: :: :.::.: . :. ::..:..:: .:.. . . .
NP_003 GKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 LLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFS
: ... .:: ...:: . ..::.:.. :: :: . . .. . :..: .::. :..
NP_003 ALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 ALIEELEEKNERPARELLTDIRSTLIRCETRK--CRKPVAVSPELGQRIRDFPQQALPLQ
.: ::: : ..:: ::. : :. : : .: ::.: . .. .: .. : ::
NP_003 LVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARV--VKKKTGEFSDKLLSLQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 REMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRA
: .. : :: .:.:. . ..::::.. : :::: . . .. .... .::.::
NP_003 RGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCE
300 310 320 330 340 350
360 370
pF1KE4 TCVLAHTGITGGRHTWVVSI-------DLAHGG---------------------------
::. :.: :. : : . : .:
NP_003 PGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDE
360 370 380 390 400 410
380 390 400 410
pF1KE4 ---------------------SCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALG
:: :::. ..:.:::.: ::::.::::.::. . . :
NP_003 DEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANT
420 430 440 450 460 470
420 430 440 450 460 470
pF1KE4 SFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGLWGRGSS
: ..: .::.: ..:::: : :::::: ..: ::::::
NP_003 SPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTR
480 490 500 510 520 530
480
pF1KE4 FSLSS
NP_003 LLLRP
>>XP_005249433 (OMIM: 600830) PREDICTED: tripartite moti (539 aa)
initn: 1225 init1: 549 opt: 905 Z-score: 652.7 bits: 130.3 E(85289): 1.3e-29
Smith-Waterman score: 1044; 37.0% identity (60.5% similar) in 522 aa overlap (1-458:1-516)
10 20 30 40 50 60
pF1KE4 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC
::..: . :: .::.: :: ::.:::::::: :::.: : : : :.::::
XP_005 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGS----RPVCPLC
10 20 30 40 50
70 80 90 100 110
pF1KE4 KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGE-----ED--VCQEHGEKIYFFCEDD
:.::. ..:: ::::..:::::::.. . :: .: .:..: ::....::::
XP_005 KKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 EMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQV
:::.:::. :: :: ..: :: :.::.: . :. ::..:..:: .:.. . . .
XP_005 GKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 LLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFS
: ... .:: ...:: . ..::.:.. :: :: . . .. . :..: .::. :..
XP_005 ALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 ALIEELEEKNERPARELLTDIRSTLIRCETRK--CRKPVAVSPELGQRIRDFPQQALPLQ
.: ::: : ..:: ::. : :. : : .: ::.: . .. .: .. : ::
XP_005 LVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARV--VKKKTGEFSDKLLSLQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 REMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRA
: .. : :: .:.:. . ..::::.. : :::: . . .. .... .::.::
XP_005 RGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCE
300 310 320 330 340 350
360 370
pF1KE4 TCVLAHTGITGGRHTWVVSI-------DLAHGG---------------------------
::. :.: :. : : . : .:
XP_005 PGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDE
360 370 380 390 400 410
380 390 400 410
pF1KE4 ---------------------SCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALG
:: :::. ..:.:::.: ::::.::::.::. . . :
XP_005 DEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANT
420 430 440 450 460 470
420 430 440 450 460 470
pF1KE4 SFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGLWGRGSS
: ..: .::.: ..:::: : :::::: ..: ::::::
XP_005 SPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTR
480 490 500 510 520 530
480
pF1KE4 FSLSS
XP_005 LLLRP
>>XP_005249435 (OMIM: 600830) PREDICTED: tripartite moti (539 aa)
initn: 1225 init1: 549 opt: 905 Z-score: 652.7 bits: 130.3 E(85289): 1.3e-29
Smith-Waterman score: 1044; 37.0% identity (60.5% similar) in 522 aa overlap (1-458:1-516)
10 20 30 40 50 60
pF1KE4 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC
::..: . :: .::.: :: ::.:::::::: :::.: : : : :.::::
XP_005 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGS----RPVCPLC
10 20 30 40 50
70 80 90 100 110
pF1KE4 KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGE-----ED--VCQEHGEKIYFFCEDD
:.::. ..:: ::::..:::::::.. . :: .: .:..: ::....::::
XP_005 KKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 EMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQV
:::.:::. :: :: ..: :: :.::.: . :. ::..:..:: .:.. . . .
XP_005 GKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 LLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFS
: ... .:: ...:: . ..::.:.. :: :: . . .. . :..: .::. :..
XP_005 ALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 ALIEELEEKNERPARELLTDIRSTLIRCETRK--CRKPVAVSPELGQRIRDFPQQALPLQ
.: ::: : ..:: ::. : :. : : .: ::.: . .. .: .. : ::
XP_005 LVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARV--VKKKTGEFSDKLLSLQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 REMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRA
: .. : :: .:.:. . ..::::.. : :::: . . .. .... .::.::
XP_005 RGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCE
300 310 320 330 340 350
360 370
pF1KE4 TCVLAHTGITGGRHTWVVSI-------DLAHGG---------------------------
::. :.: :. : : . : .:
XP_005 PGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDE
360 370 380 390 400 410
380 390 400 410
pF1KE4 ---------------------SCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALG
:: :::. ..:.:::.: ::::.::::.::. . . :
XP_005 DEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANT
420 430 440 450 460 470
420 430 440 450 460 470
pF1KE4 SFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGLWGRGSS
: ..: .::.: ..:::: : :::::: ..: ::::::
XP_005 SPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTR
480 490 500 510 520 530
480
pF1KE4 FSLSS
XP_005 LLLRP
481 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:14:02 2016 done: Sun Nov 6 03:14:04 2016
Total Scan time: 10.080 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]