FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4104, 473 aa
  1>>>pF1KE4104 473 - 473 aa - 473 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.6720+/-0.000687; mu= 14.1569+/- 0.042
 mean_var=124.8895+/-25.349, 0's: 0 Z-trim(114.1): 28  B-trim: 952 in 2/51
 Lambda= 0.114765
 statistics sampled from 14682 (14709) to 14682 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.452), width:  16
 Scan time:  2.860

The best scores are:                                      opt bits E(32554)
CCDS3467.1 KCTD8 gene_id:386617|Hs108|chr4         ( 473) 3165 534.6 8.3e-152
CCDS34260.1 KCTD16 gene_id:57528|Hs108|chr5        ( 428) 1144 200.0 4.2e-51
CCDS9455.1 KCTD12 gene_id:115207|Hs108|chr13       ( 325)  630 114.8 1.4e-25


>>CCDS3467.1 KCTD8 gene_id:386617|Hs108|chr4              (473 aa)
 initn: 3165 init1: 3165 opt: 3165  Z-score: 2838.9  bits: 534.6 E(32554): 8.3e-152
Smith-Waterman score: 3165; 100.0% identity (100.0% similar) in 473 aa overlap (1-473:1-473)

               10        20        30        40        50        60
pF1KE4 MALKDTGSGGSTILPISEMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MALKDTGSGGSTILPISEMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 TLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 TLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLAL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 PEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALLLR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 GAAAAVPSGPGAHGGGGGGGAQDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 GAAAAVPSGPGAHGGGGGGGAQDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 IALAKEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 IALAKEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE4 FVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKHDKVTDKGSESGTSCNELSTSSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 FVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKHDKVTDKGSESGTSCNELSTSSC
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE4 DSHSEASTPQDNPSSAQQATAHQPNTLTLDRPSKKAPVQWIPPPDKRRNSELFQTLISKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 DSHSEASTPQDNPSSAQQATAHQPNTLTLDRPSKKAPVQWIPPPDKRRNSELFQTLISKS
              370       380       390       400       410       420

              430       440       450       460       470   
pF1KE4 RETNLSKKKVCEKLSVEEEMKKCIQDFKKIHIPDYFPERKRQWQSELLQKYGL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 RETNLSKKKVCEKLSVEEEMKKCIQDFKKIHIPDYFPERKRQWQSELLQKYGL
              430       440       450       460       470   

>>CCDS34260.1 KCTD16 gene_id:57528|Hs108|chr5             (428 aa)
 initn: 1681 init1: 652 opt: 1144  Z-score: 1031.0  bits: 200.0 E(32554): 4.2e-51
Smith-Waterman score: 1669; 61.7% identity (78.2% similar) in 441 aa overlap (35-473:16-428)

           10        20        30        40        50        60    
pF1KE4 DTGSGGSTILPISEMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLS
                                     :  .:. :::::::::::::: :.::::.:
CCDS34                MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLIS
                              10        20        30        40     

           70        80        90       100       110       120    
pF1KE4 VPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHF
       .: : : .::::.  :  :   ..: .::..:::::::::::::.::::::.:..::.::
CCDS34 IPHSLLWKMFSPK--RDTA---NDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHF
          50          60           70        80        90       100

          130       140       150       160       170       180    
pF1KE4 PEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALLLRGAAA
       ::: :: :::::::: ::::::.:   ::.   :: :.::.:: .::::.  .     ..
CCDS34 PEKGRLKREAEYFQLPDLVKLLTPDEIKQSP--DEFCHSDFED-ASQGSDTRIC--PPSS
              110       120       130         140        150       

          190       200       210       220       230       240    
pF1KE4 AVPSGPGAHGGGGGGGAQDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGRIALA
        .:.              :.. ::.:.::::: :  :..::::::::: ::.:::::.::
CCDS34 LLPA--------------DRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLA
                       160       170       180       190       200 

          250       260       270       280       290       300    
pF1KE4 KEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAAFVNQ
       :::::.:::::::::: ::.::::::::: .::.::: ::: :::::::::: ::.:.::
CCDS34 KEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDMLSECGFHMVACNSSVTASFINQ
             210       220       230       240       250       260 

          310       320       330       340       350       360    
pF1KE4 YRDDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKHDKVTDKGSESGTSCNELSTSSCDSHS
       : :::::::::::.:.: :..  ::..     :. :  :: .:::::::.::::::::.:
CCDS34 YTDDKIWSSYTEYVFYREPSRW-SPSHCDCCCKNGK-GDKEGESGTSCNDLSTSSCDSQS
             270       280        290        300       310         

          370       380       390       400       410       420    
pF1KE4 EASTPQDNPSSAQQATAHQPNTLTLDRPSKKAPVQWIPPPDKRRNSELFQTLISKSRETN
       :::.::.  .     ...: :  ::::: ::.::: :   . ::.:.:..:: : :::.:
CCDS34 EASSPQE--TVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMRRKSDLLRTLTSGSRESN
     320         330       340       350       360       370       

            430       440       450       460       470   
pF1KE4 LSKKK--VCEKLSVEEEMKKCIQDFKKIHIPDYFPERKRQWQSELLQKYGL
       .:.::  : ::::.:::..:::::: ::.::: :::::. ::::::.:: :
CCDS34 MSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQSELLRKYHL
       380       390       400       410       420        

>>CCDS9455.1 KCTD12 gene_id:115207|Hs108|chr13            (325 aa)
 initn: 894 init1: 540 opt: 630  Z-score: 572.7  bits: 114.8 E(32554): 1.4e-25
Smith-Waterman score: 1056; 51.9% identity (73.8% similar) in 343 aa overlap (1-321:1-324)

               10        20        30        40        50        60
pF1KE4 MALKDTGSGGSTILPISEMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHS
       ::: :.  :    ::      .... :...... .   :  ::..::::::::::::.. 
CCDS94 MALADSTRG----LP------NGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRC
                   10              20        30        40        50

               70        80        90       100       110       120
pF1KE4 TLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLAL
       :..::::: :  ::. ..:.       :: :::..:::.:::::::::.:::::: ::.:
CCDS94 TVVSVPDSLLWRMFTQQQPQ-------ELARDSKGRFFLDRDGFLFRYILDYLRDLQLVL
               60        70               80        90       100   

              130       140        150             160       170   
pF1KE4 PEHFPEKERLLREAEYFQLTDLVKLL-SPKVT------KQNSLNDEGCQSDLEDNVSQGS
       :..:::. :: ::::::.: .::. : .:.        .. ... ::  .:  . .  : 
CCDS94 PDYFPERSRLQREAEYFELPELVRRLGAPQQPGPGPPPSRRGVHKEGSLGD--ELLPLGY
           110       120       130       140       150         160 

           180            190       200               210       220
pF1KE4 SDALLLRGAAAAVPS-----GPGAHGGGGGGG----AQD----KRSGFLTLGYRGSYTTV
       :.    .::.:..::     .  . .::..:     .:.    .:::..:.:::::::  
CCDS94 SEPEQQEGASAGAPSPTLELASRSPSGGAAGPLLTPSQSLDGSRRSGYITIGYRGSYTIG
             170       180       190       200       210       220 

              230       240       250       260       270       280
pF1KE4 RDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAF
       :: :::::::::::: :::. .:::::::::::::::::: ::.::::.::::..:::::
CCDS94 RDAQADAKFRRVARITVCGKTSLAKEVFGDTLNESRDPDRPPERYTSRYYLKFNFLEQAF
             230       240       250       260       270       280 

              290       300         310       320       330        
pF1KE4 DRLSEAGFHMVACNSSGTAAFVNQ--YRDDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKH
       :.:::.:::::::.:.:: ::...    .::::.:::::.: :                 
CCDS94 DKLSESGFHMVACSSTGTCAFASSTDQSEDKIWTSYTEYVFCRE                
             290       300       310       320                     

      340       350       360       370       380       390        
pF1KE4 DKVTDKGSESGTSCNELSTSSCDSHSEASTPQDNPSSAQQATAHQPNTLTLDRPSKKAPV




473 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 01:44:07 2016 done: Sun Nov  6 01:44:07 2016
 Total Scan time:  2.860 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]