FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4083, 435 aa
  1>>>pF1KE4083 435 - 435 aa - 435 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.6885+/-0.000417; mu= 11.8821+/- 0.026
 mean_var=165.8710+/-36.503, 0's: 0 Z-trim(115.9): 141  B-trim: 1622 in 1/51
 Lambda= 0.099584
 statistics sampled from 26553 (26754) to 26553 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.314), width:  16
 Scan time:  8.060

The best scores are:                                      opt bits E(85289)
NP_057209 (OMIM: 615172) RING finger and transmemb ( 435) 2981 440.8 3.3e-123
NP_002608 (OMIM: 602859,614870,614871) peroxisome  ( 326)  195 40.4  0.0085


>>NP_057209 (OMIM: 615172) RING finger and transmembrane  (435 aa)
 initn: 2981 init1: 2981 opt: 2981  Z-score: 2332.9  bits: 440.8 E(85289): 3.3e-123
Smith-Waterman score: 2981; 100.0% identity (100.0% similar) in 435 aa overlap (1-435:1-435)

               10        20        30        40        50        60
pF1KE4 MPLFLLSLPTPPSASGHERRQRPEAKTSGSEKKYLRAMQANRSQLHSPPGTGSSEDASTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MPLFLLSLPTPPSASGHERRQRPEAKTSGSEKKYLRAMQANRSQLHSPPGTGSSEDASTP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 QCVHTRLTGEGSCPHSGDVHIQINSIPKECAENASSRNIRSGVHSCAHGCVHSRLRGHSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QCVHTRLTGEGSCPHSGDVHIQINSIPKECAENASSRNIRSGVHSCAHGCVHSRLRGHSH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 SEARLTDDTAAESGDHGSSSFSEFRYLFKWLQKSLPYILILSVKLVMQHITGISLGIGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SEARLTDDTAAESGDHGSSSFSEFRYLFKWLQKSLPYILILSVKLVMQHITGISLGIGLL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 TTFMYANKSIVNQVFLRERSSKIQCAWLLVFLAGSSVLLYYTFHSQSLYYSLIFLNPTLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TTFMYANKSIVNQVFLRERSSKIQCAWLLVFLAGSSVLLYYTFHSQSLYYSLIFLNPTLD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 HLSFWEVFWIVGITDFILKFFFMGLKCLILLVPSFIMPFKSKGYWYMLLEELCQYYRTFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 HLSFWEVFWIVGITDFILKFFFMGLKCLILLVPSFIMPFKSKGYWYMLLEELCQYYRTFV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE4 PIPVWFRYLISYGEFGNVTRWSLGILLALLYLILKLLEFFGHLRTFRQVLRIFFTQPSYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PIPVWFRYLISYGEFGNVTRWSLGILLALLYLILKLLEFFGHLRTFRQVLRIFFTQPSYG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE4 VAASKRQCSDVDDICSICQAEFQKPILLICQHIFCEECMTLWFNREKTCPLCRTVISDHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VAASKRQCSDVDDICSICQAEFQKPILLICQHIFCEECMTLWFNREKTCPLCRTVISDHI
              370       380       390       400       410       420

              430     
pF1KE4 NKWKDGATSSHLQIY
       :::::::::::::::
NP_057 NKWKDGATSSHLQIY
              430     

>>NP_002608 (OMIM: 602859,614870,614871) peroxisome biog  (326 aa)
 initn: 147 init1: 125 opt: 195  Z-score: 171.2  bits: 40.4 E(85289): 0.0085
Smith-Waterman score: 199; 28.7% identity (53.7% similar) in 164 aa overlap (256-413:165-311)

         230       240       250       260       270       280     
pF1KE4 QSLYYSLIFLNPTLDHLSFWEVFWIVGITDFILKFFFMGLKCLILLVPSFIMPFKSKGYW
                                     :.:.   .:: ::  :    .  :  .: .
NP_002 GRGCSGARRWMRHHTATLTEQQRRALLRAVFVLR---QGLACLQRL---HVAWFYIHGVF
          140       150       160          170          180        

         290       300       310       320       330        340    
pF1KE4 YMLLEELCQYYRTFVPIPVWFRYLISYGEFGNVTRWSLGILLALLYLILKL-LEFFGHLR
       : : ..:     :.. .    : : .    . :.   ::.. .::.:.:.. :...:   
NP_002 YHLAKRLTGI--TYLRV----RSLPGEDLRARVSYRLLGVI-SLLHLVLSMGLQLYG---
      190         200           210       220        230           

          350            360       370       380       390         
pF1KE4 TFRQVLRI-----FFTQPSYGVAASKRQCSDVDDICSICQAEFQKPILLICQHIFCEECM
        :::  :      .    :.  :. ...  . . .:..:  : ..:    : :.:: ::.
NP_002 -FRQRQRARKEWRLHRGLSHRRASLEERAVSRNPLCTLCLEERRHPTATPCGHLFCWECI
       240       250       260       270       280       290       

     400       410       420       430     
pF1KE4 TLWFNREKTCPLCRTVISDHINKWKDGATSSHLQIY
       : : . .  :::::                      
NP_002 TAWCSSKAECPLCREKFPPQKLIYLRHYR       
       300       310       320             




435 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 03:58:16 2016 done: Sun Nov  6 03:58:17 2016
 Total Scan time:  8.060 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]