Result of FASTA (omim) for
pFN21AE4082
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4082, 429 aa
1>>>pF1KE4082 429 - 429 aa - 429 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1948+/-0.000336; mu= 10.8055+/- 0.021
mean_var=185.3387+/-38.069, 0's: 0 Z-trim(121.4): 117 B-trim: 457 in 2/52
Lambda= 0.094209
statistics sampled from 37907 (38068) to 37907 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.446), width: 16
Scan time: 9.930
The best scores are: opt bits E(85289)
NP_859061 (OMIM: 612063) E3 ubiquitin-protein liga ( 429) 2998 419.6 7.9e-117
XP_016861144 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 753 114.4 5.2e-25
XP_011510676 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 753 114.4 5.2e-25
NP_899237 (OMIM: 609247) E3 ubiquitin-protein liga ( 381) 753 114.4 5.2e-25
XP_016861143 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 753 114.4 5.2e-25
NP_009213 (OMIM: 609247) E3 ubiquitin-protein liga ( 381) 753 114.4 5.2e-25
XP_011510675 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 753 114.4 5.2e-25
NP_001307288 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 735 111.9 2.7e-24
NP_056343 (OMIM: 610431) E3 ubiquitin-protein liga ( 350) 735 111.9 2.7e-24
NP_001307286 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 735 111.9 2.7e-24
NP_001307290 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 735 111.9 2.7e-24
NP_001307285 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 735 111.9 2.7e-24
XP_016879916 (OMIM: 610431) PREDICTED: E3 ubiquiti ( 350) 735 111.9 2.7e-24
NP_001307289 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 735 111.9 2.7e-24
NP_001307287 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 735 111.9 2.7e-24
NP_001307291 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 704 107.6 4.6e-23
NP_001307292 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 704 107.6 4.6e-23
NP_001307293 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 704 107.6 4.6e-23
NP_001307294 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 704 107.6 4.6e-23
XP_016861149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 250) 396 65.7 1.6e-10
XP_005247149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 396 65.7 1.6e-10
XP_016861145 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 396 65.7 1.6e-10
XP_011510678 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 396 65.7 1.6e-10
XP_016861146 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 396 65.7 1.6e-10
XP_016861148 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 396 65.7 1.6e-10
XP_016861147 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 396 65.7 1.6e-10
XP_016861150 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 193) 346 58.7 1.5e-08
XP_016879917 (OMIM: 610431) PREDICTED: E3 ubiquiti ( 227) 311 54.1 4.4e-07
NP_057204 (OMIM: 300379,300978) E3 ubiquitin-prote ( 624) 222 42.4 0.0038
NP_899196 (OMIM: 300379,300978) E3 ubiquitin-prote ( 624) 222 42.4 0.0038
NP_115549 (OMIM: 612062) E3 ubiquitin-protein liga ( 836) 221 42.4 0.0051
XP_011528739 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 221 42.4 0.0052
XP_011528740 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 221 42.4 0.0052
XP_011528737 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 221 42.4 0.0052
XP_011528738 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 221 42.4 0.0052
XP_016884479 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 221 42.4 0.0052
NP_001193927 (OMIM: 612062) E3 ubiquitin-protein l ( 936) 221 42.5 0.0055
NP_001292474 (OMIM: 612482,617108) E3 ubiquitin-pr ( 656) 217 41.8 0.0064
XP_011523258 (OMIM: 612482,617108) PREDICTED: E3 u ( 742) 217 41.8 0.0069
NP_001292473 (OMIM: 612482,617108) E3 ubiquitin-pr ( 783) 217 41.9 0.0072
NP_060233 (OMIM: 612482,617108) E3 ubiquitin-prote ( 783) 217 41.9 0.0072
XP_011523257 (OMIM: 612482,617108) PREDICTED: E3 u ( 869) 217 41.9 0.0077
XP_016880289 (OMIM: 612482,617108) PREDICTED: E3 u ( 869) 217 41.9 0.0077
>>NP_859061 (OMIM: 612063) E3 ubiquitin-protein ligase Z (429 aa)
initn: 2998 init1: 2998 opt: 2998 Z-score: 2218.5 bits: 419.6 E(85289): 7.9e-117
Smith-Waterman score: 2998; 99.5% identity (100.0% similar) in 429 aa overlap (1-429:1-429)
10 20 30 40 50 60
pF1KE4 MPLCRPEHLMPRASRVPVAASLPLSHAVIPTQLPSRPGHRPPGRPRRCPKASCLPPPVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 MPLCRPEHLMPRASRVPVAASLPLSHAVIPTQLPSRPGHRPPGRPRRCPKASCLPPPVGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SSTQTAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSSSVDFADLPALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 SSTQTAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSSSVDFADLPALF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GVPLAPEGIRGYLMEVKPANACHPIEAPRLGNRSLGSIALIRRYDCTFDLKVLNAQRAGF
::::::::::::::::::::::::::::::::::::.:.:::::::::::::::::::::
NP_859 GVPLAPEGIRGYLMEVKPANACHPIEAPRLGNRSLGAIVLIRRYDCTFDLKVLNAQRAGF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 EAAIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGCNKSAHALLLPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 EAAIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGCNKSAHALLLPDD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 PPCHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRPVKTSTCQKAQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 PPCHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRPVKTSTCQKAQVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 TFTWHNDLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQSVAATED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 TFTWHNDLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQSVAATED
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 SFDSTTYSFRDEDPSLPGHRPPIWAIQVQLRSRRLELLGRASPHCHCSTTSLEAEYTTVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 SFDSTTYSFRDEDPSLPGHRPPIWAIQVQLRSRRLELLGRASPHCHCSTTSLEAEYTTVS
370 380 390 400 410 420
pF1KE4 SAPPEAPGQ
:::::::::
NP_859 SAPPEAPGQ
>>XP_016861144 (OMIM: 609247) PREDICTED: E3 ubiquitin-pr (381 aa)
initn: 615 init1: 276 opt: 753 Z-score: 570.1 bits: 114.4 E(85289): 5.2e-25
Smith-Waterman score: 753; 40.8% identity (69.0% similar) in 316 aa overlap (80-389:18-321)
50 60 70 80 90 100
pF1KE4 KASCLPPPVGPSSTQTAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSS
...:. . :.:: :..: . : .:.:
XP_016 MLLSIGMLMLSATQVYTILTVQLFAFLNLL--PVEADILAYNFENAS
10 20 30 40
110 120 130 140 150 160
pF1KE4 SVDFADLPALFGVPLAPEGIRGYLMEVKPANACHPIEAPRLGNRSLGS-IALIRRYDCTF
.. : :::: :: : ::..:.:.. :: :::.:: : . . : :. :.:::: ::.:
XP_016 QT-FDDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNF
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 DLKVLNAQRAGFEAAIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGC
:.:::::::::..::::::: ::::.:: .. .: :::::..:.....:. .
XP_016 DIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTY
110 120 130 140 150 160
230 240 250 260 270 280
pF1KE4 NKSAHALLLPDDPPCHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRP
.:..: .:.:. . : : . .: : :.: :.. . . .: .:
XP_016 EKGGHLILVPEFSLPLEYYLIPFLII---VGICLILIV-IFMITKFVQDRHRA---RRNR
170 180 190 200 210
290 300 310 320 330 340
pF1KE4 VKTSTCQKAQVRTFTWHN--DLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRR
.. . .: :. : . :.:::::::::.::.:.::::::.:::::.:::.... ..
XP_016 LRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKT-KK
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 SCPVCKQSVAATEDSFDSTTYSFRDEDPSLPGHRP---PIWAIQVQLRSRRLELLGRASP
.::::::.:. .. . :: : : ..:. . : : :. ....:
XP_016 TCPVCKQKVVPSQGDSDSDTDSSQEENE-VTEHTPLLRPLASVSAQSFGALSESRSHQNM
280 290 300 310 320 330
410 420
pF1KE4 HCHCSTTSLEAEYTTVSSAPPEAPGQ
XP_016 TESSDYEEDDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV
340 350 360 370 380
>>XP_011510676 (OMIM: 609247) PREDICTED: E3 ubiquitin-pr (381 aa)
initn: 615 init1: 276 opt: 753 Z-score: 570.1 bits: 114.4 E(85289): 5.2e-25
Smith-Waterman score: 753; 40.8% identity (69.0% similar) in 316 aa overlap (80-389:18-321)
50 60 70 80 90 100
pF1KE4 KASCLPPPVGPSSTQTAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSS
...:. . :.:: :..: . : .:.:
XP_011 MLLSIGMLMLSATQVYTILTVQLFAFLNLL--PVEADILAYNFENAS
10 20 30 40
110 120 130 140 150 160
pF1KE4 SVDFADLPALFGVPLAPEGIRGYLMEVKPANACHPIEAPRLGNRSLGS-IALIRRYDCTF
.. : :::: :: : ::..:.:.. :: :::.:: : . . : :. :.:::: ::.:
XP_011 QT-FDDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNF
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 DLKVLNAQRAGFEAAIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGC
:.:::::::::..::::::: ::::.:: .. .: :::::..:.....:. .
XP_011 DIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTY
110 120 130 140 150 160
230 240 250 260 270 280
pF1KE4 NKSAHALLLPDDPPCHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRP
.:..: .:.:. . : : . .: : :.: :.. . . .: .:
XP_011 EKGGHLILVPEFSLPLEYYLIPFLII---VGICLILIV-IFMITKFVQDRHRA---RRNR
170 180 190 200 210
290 300 310 320 330 340
pF1KE4 VKTSTCQKAQVRTFTWHN--DLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRR
.. . .: :. : . :.:::::::::.::.:.::::::.:::::.:::.... ..
XP_011 LRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKT-KK
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 SCPVCKQSVAATEDSFDSTTYSFRDEDPSLPGHRP---PIWAIQVQLRSRRLELLGRASP
.::::::.:. .. . :: : : ..:. . : : :. ....:
XP_011 TCPVCKQKVVPSQGDSDSDTDSSQEENE-VTEHTPLLRPLASVSAQSFGALSESRSHQNM
280 290 300 310 320 330
410 420
pF1KE4 HCHCSTTSLEAEYTTVSSAPPEAPGQ
XP_011 TESSDYEEDDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV
340 350 360 370 380
>>NP_899237 (OMIM: 609247) E3 ubiquitin-protein ligase R (381 aa)
initn: 615 init1: 276 opt: 753 Z-score: 570.1 bits: 114.4 E(85289): 5.2e-25
Smith-Waterman score: 753; 40.8% identity (69.0% similar) in 316 aa overlap (80-389:18-321)
50 60 70 80 90 100
pF1KE4 KASCLPPPVGPSSTQTAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSS
...:. . :.:: :..: . : .:.:
NP_899 MLLSIGMLMLSATQVYTILTVQLFAFLNLL--PVEADILAYNFENAS
10 20 30 40
110 120 130 140 150 160
pF1KE4 SVDFADLPALFGVPLAPEGIRGYLMEVKPANACHPIEAPRLGNRSLGS-IALIRRYDCTF
.. : :::: :: : ::..:.:.. :: :::.:: : . . : :. :.:::: ::.:
NP_899 QT-FDDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNF
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 DLKVLNAQRAGFEAAIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGC
:.:::::::::..::::::: ::::.:: .. .: :::::..:.....:. .
NP_899 DIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTY
110 120 130 140 150 160
230 240 250 260 270 280
pF1KE4 NKSAHALLLPDDPPCHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRP
.:..: .:.:. . : : . .: : :.: :.. . . .: .:
NP_899 EKGGHLILVPEFSLPLEYYLIPFLII---VGICLILIV-IFMITKFVQDRHRA---RRNR
170 180 190 200 210
290 300 310 320 330 340
pF1KE4 VKTSTCQKAQVRTFTWHN--DLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRR
.. . .: :. : . :.:::::::::.::.:.::::::.:::::.:::.... ..
NP_899 LRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKT-KK
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 SCPVCKQSVAATEDSFDSTTYSFRDEDPSLPGHRP---PIWAIQVQLRSRRLELLGRASP
.::::::.:. .. . :: : : ..:. . : : :. ....:
NP_899 TCPVCKQKVVPSQGDSDSDTDSSQEENE-VTEHTPLLRPLASVSAQSFGALSESRSHQNM
280 290 300 310 320 330
410 420
pF1KE4 HCHCSTTSLEAEYTTVSSAPPEAPGQ
NP_899 TESSDYEEDDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV
340 350 360 370 380
>>XP_016861143 (OMIM: 609247) PREDICTED: E3 ubiquitin-pr (381 aa)
initn: 615 init1: 276 opt: 753 Z-score: 570.1 bits: 114.4 E(85289): 5.2e-25
Smith-Waterman score: 753; 40.8% identity (69.0% similar) in 316 aa overlap (80-389:18-321)
50 60 70 80 90 100
pF1KE4 KASCLPPPVGPSSTQTAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSS
...:. . :.:: :..: . : .:.:
XP_016 MLLSIGMLMLSATQVYTILTVQLFAFLNLL--PVEADILAYNFENAS
10 20 30 40
110 120 130 140 150 160
pF1KE4 SVDFADLPALFGVPLAPEGIRGYLMEVKPANACHPIEAPRLGNRSLGS-IALIRRYDCTF
.. : :::: :: : ::..:.:.. :: :::.:: : . . : :. :.:::: ::.:
XP_016 QT-FDDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNF
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 DLKVLNAQRAGFEAAIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGC
:.:::::::::..::::::: ::::.:: .. .: :::::..:.....:. .
XP_016 DIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTY
110 120 130 140 150 160
230 240 250 260 270 280
pF1KE4 NKSAHALLLPDDPPCHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRP
.:..: .:.:. . : : . .: : :.: :.. . . .: .:
XP_016 EKGGHLILVPEFSLPLEYYLIPFLII---VGICLILIV-IFMITKFVQDRHRA---RRNR
170 180 190 200 210
290 300 310 320 330 340
pF1KE4 VKTSTCQKAQVRTFTWHN--DLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRR
.. . .: :. : . :.:::::::::.::.:.::::::.:::::.:::.... ..
XP_016 LRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKT-KK
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 SCPVCKQSVAATEDSFDSTTYSFRDEDPSLPGHRP---PIWAIQVQLRSRRLELLGRASP
.::::::.:. .. . :: : : ..:. . : : :. ....:
XP_016 TCPVCKQKVVPSQGDSDSDTDSSQEENE-VTEHTPLLRPLASVSAQSFGALSESRSHQNM
280 290 300 310 320 330
410 420
pF1KE4 HCHCSTTSLEAEYTTVSSAPPEAPGQ
XP_016 TESSDYEEDDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV
340 350 360 370 380
>>NP_009213 (OMIM: 609247) E3 ubiquitin-protein ligase R (381 aa)
initn: 615 init1: 276 opt: 753 Z-score: 570.1 bits: 114.4 E(85289): 5.2e-25
Smith-Waterman score: 753; 40.8% identity (69.0% similar) in 316 aa overlap (80-389:18-321)
50 60 70 80 90 100
pF1KE4 KASCLPPPVGPSSTQTAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSS
...:. . :.:: :..: . : .:.:
NP_009 MLLSIGMLMLSATQVYTILTVQLFAFLNLL--PVEADILAYNFENAS
10 20 30 40
110 120 130 140 150 160
pF1KE4 SVDFADLPALFGVPLAPEGIRGYLMEVKPANACHPIEAPRLGNRSLGS-IALIRRYDCTF
.. : :::: :: : ::..:.:.. :: :::.:: : . . : :. :.:::: ::.:
NP_009 QT-FDDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNF
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 DLKVLNAQRAGFEAAIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGC
:.:::::::::..::::::: ::::.:: .. .: :::::..:.....:. .
NP_009 DIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTY
110 120 130 140 150 160
230 240 250 260 270 280
pF1KE4 NKSAHALLLPDDPPCHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRP
.:..: .:.:. . : : . .: : :.: :.. . . .: .:
NP_009 EKGGHLILVPEFSLPLEYYLIPFLII---VGICLILIV-IFMITKFVQDRHRA---RRNR
170 180 190 200 210
290 300 310 320 330 340
pF1KE4 VKTSTCQKAQVRTFTWHN--DLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRR
.. . .: :. : . :.:::::::::.::.:.::::::.:::::.:::.... ..
NP_009 LRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKT-KK
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 SCPVCKQSVAATEDSFDSTTYSFRDEDPSLPGHRP---PIWAIQVQLRSRRLELLGRASP
.::::::.:. .. . :: : : ..:. . : : :. ....:
NP_009 TCPVCKQKVVPSQGDSDSDTDSSQEENE-VTEHTPLLRPLASVSAQSFGALSESRSHQNM
280 290 300 310 320 330
410 420
pF1KE4 HCHCSTTSLEAEYTTVSSAPPEAPGQ
NP_009 TESSDYEEDDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV
340 350 360 370 380
>>XP_011510675 (OMIM: 609247) PREDICTED: E3 ubiquitin-pr (381 aa)
initn: 615 init1: 276 opt: 753 Z-score: 570.1 bits: 114.4 E(85289): 5.2e-25
Smith-Waterman score: 753; 40.8% identity (69.0% similar) in 316 aa overlap (80-389:18-321)
50 60 70 80 90 100
pF1KE4 KASCLPPPVGPSSTQTAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSS
...:. . :.:: :..: . : .:.:
XP_011 MLLSIGMLMLSATQVYTILTVQLFAFLNLL--PVEADILAYNFENAS
10 20 30 40
110 120 130 140 150 160
pF1KE4 SVDFADLPALFGVPLAPEGIRGYLMEVKPANACHPIEAPRLGNRSLGS-IALIRRYDCTF
.. : :::: :: : ::..:.:.. :: :::.:: : . . : :. :.:::: ::.:
XP_011 QT-FDDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNF
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 DLKVLNAQRAGFEAAIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGC
:.:::::::::..::::::: ::::.:: .. .: :::::..:.....:. .
XP_011 DIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTY
110 120 130 140 150 160
230 240 250 260 270 280
pF1KE4 NKSAHALLLPDDPPCHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRP
.:..: .:.:. . : : . .: : :.: :.. . . .: .:
XP_011 EKGGHLILVPEFSLPLEYYLIPFLII---VGICLILIV-IFMITKFVQDRHRA---RRNR
170 180 190 200 210
290 300 310 320 330 340
pF1KE4 VKTSTCQKAQVRTFTWHN--DLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRR
.. . .: :. : . :.:::::::::.::.:.::::::.:::::.:::.... ..
XP_011 LRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKT-KK
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 SCPVCKQSVAATEDSFDSTTYSFRDEDPSLPGHRP---PIWAIQVQLRSRRLELLGRASP
.::::::.:. .. . :: : : ..:. . : : :. ....:
XP_011 TCPVCKQKVVPSQGDSDSDTDSSQEENE-VTEHTPLLRPLASVSAQSFGALSESRSHQNM
280 290 300 310 320 330
410 420
pF1KE4 HCHCSTTSLEAEYTTVSSAPPEAPGQ
XP_011 TESSDYEEDDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV
340 350 360 370 380
>>NP_001307288 (OMIM: 610431) E3 ubiquitin-protein ligas (350 aa)
initn: 747 init1: 300 opt: 735 Z-score: 557.3 bits: 111.9 E(85289): 2.7e-24
Smith-Waterman score: 785; 39.7% identity (67.5% similar) in 348 aa overlap (95-427:21-342)
70 80 90 100 110 120
pF1KE4 TAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSSSVDFADLPALFGVPL
:.....::. :...:.::::::::::. :
NP_001 MHPAAFPLPVVVAAVLWGAAPTRGLIRAT-SDHNASMDFADLPALFGATL
10 20 30 40
130 140 150 160 170 180
pF1KE4 APEGIRGYLMEVKPANACHPIEAPRLGNRSLGS--IALIRRYDCTFDLKVLNAQRAGFEA
. ::..:.:.:..: ::: :: : . . :: :::.::.::.:::::::::.::. :
NP_001 SQEGLQGFLVEAHPDNACSPIAPPPPAPVN-GSVFIALLRRFDCNFDLKVLNAQKAGYGA
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE4 AIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGCNKSAHALLLPDDPP
:.::::.:..:..:. :... :: :::::..: .:. ::... .:.:..::.::.
NP_001 AVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNT-
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE4 CHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRPVKTSTCQKAQVRTF
:: . .. . ..: :.:...: .. : .::. .. . : :.. .
NP_001 -FPLGYY-LIPFTGIVG-LLVLAMGAVMI--------ARCIQHRKRLQRNRLTKEQLKQI
170 180 190 200 210
310 320 330 340 350
pF1KE4 TWHN-------DLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQSV
:. :.:::::::::.::.:..:::.:.:: .:.:::..:. :..::.::: :
NP_001 PTHDYQKGDQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQT-RKTCPICKQPV
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE4 ---AATEDSFDSTTYSFRDEDPSLPGHRPPIWAIQVQLRSRRLELLGRASPHCHCSTTSL
. ::. . : . .. : . : .: :.: ::: .:: : ::
NP_001 HRGPGDEDQ-EEETQGQEEGDEGEPRDHPA---------SERTPLLG-SSPTLPTSFGSL
280 290 300 310 320
420
pF1KE4 EAE---YTTVSSAPPEAPGQ
. :. :: .:
NP_001 APAPLVFPGPSTDPPLSPPSSPVILV
330 340 350
>>NP_056343 (OMIM: 610431) E3 ubiquitin-protein ligase R (350 aa)
initn: 747 init1: 300 opt: 735 Z-score: 557.3 bits: 111.9 E(85289): 2.7e-24
Smith-Waterman score: 785; 39.7% identity (67.5% similar) in 348 aa overlap (95-427:21-342)
70 80 90 100 110 120
pF1KE4 TAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSSSVDFADLPALFGVPL
:.....::. :...:.::::::::::. :
NP_056 MHPAAFPLPVVVAAVLWGAAPTRGLIRAT-SDHNASMDFADLPALFGATL
10 20 30 40
130 140 150 160 170 180
pF1KE4 APEGIRGYLMEVKPANACHPIEAPRLGNRSLGS--IALIRRYDCTFDLKVLNAQRAGFEA
. ::..:.:.:..: ::: :: : . . :: :::.::.::.:::::::::.::. :
NP_056 SQEGLQGFLVEAHPDNACSPIAPPPPAPVN-GSVFIALLRRFDCNFDLKVLNAQKAGYGA
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE4 AIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGCNKSAHALLLPDDPP
:.::::.:..:..:. :... :: :::::..: .:. ::... .:.:..::.::.
NP_056 AVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNT-
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE4 CHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRPVKTSTCQKAQVRTF
:: . .. . ..: :.:...: .. : .::. .. . : :.. .
NP_056 -FPLGYY-LIPFTGIVG-LLVLAMGAVMI--------ARCIQHRKRLQRNRLTKEQLKQI
170 180 190 200 210
310 320 330 340 350
pF1KE4 TWHN-------DLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQSV
:. :.:::::::::.::.:..:::.:.:: .:.:::..:. :..::.::: :
NP_056 PTHDYQKGDQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQT-RKTCPICKQPV
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE4 ---AATEDSFDSTTYSFRDEDPSLPGHRPPIWAIQVQLRSRRLELLGRASPHCHCSTTSL
. ::. . : . .. : . : .: :.: ::: .:: : ::
NP_056 HRGPGDEDQ-EEETQGQEEGDEGEPRDHPA---------SERTPLLG-SSPTLPTSFGSL
280 290 300 310 320
420
pF1KE4 EAE---YTTVSSAPPEAPGQ
. :. :: .:
NP_056 APAPLVFPGPSTDPPLSPPSSPVILV
330 340 350
>>NP_001307286 (OMIM: 610431) E3 ubiquitin-protein ligas (350 aa)
initn: 747 init1: 300 opt: 735 Z-score: 557.3 bits: 111.9 E(85289): 2.7e-24
Smith-Waterman score: 785; 39.7% identity (67.5% similar) in 348 aa overlap (95-427:21-342)
70 80 90 100 110 120
pF1KE4 TAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSSSVDFADLPALFGVPL
:.....::. :...:.::::::::::. :
NP_001 MHPAAFPLPVVVAAVLWGAAPTRGLIRAT-SDHNASMDFADLPALFGATL
10 20 30 40
130 140 150 160 170 180
pF1KE4 APEGIRGYLMEVKPANACHPIEAPRLGNRSLGS--IALIRRYDCTFDLKVLNAQRAGFEA
. ::..:.:.:..: ::: :: : . . :: :::.::.::.:::::::::.::. :
NP_001 SQEGLQGFLVEAHPDNACSPIAPPPPAPVN-GSVFIALLRRFDCNFDLKVLNAQKAGYGA
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE4 AIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGCNKSAHALLLPDDPP
:.::::.:..:..:. :... :: :::::..: .:. ::... .:.:..::.::.
NP_001 AVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNT-
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE4 CHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRPVKTSTCQKAQVRTF
:: . .. . ..: :.:...: .. : .::. .. . : :.. .
NP_001 -FPLGYY-LIPFTGIVG-LLVLAMGAVMI--------ARCIQHRKRLQRNRLTKEQLKQI
170 180 190 200 210
310 320 330 340 350
pF1KE4 TWHN-------DLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQSV
:. :.:::::::::.::.:..:::.:.:: .:.:::..:. :..::.::: :
NP_001 PTHDYQKGDQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQT-RKTCPICKQPV
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE4 ---AATEDSFDSTTYSFRDEDPSLPGHRPPIWAIQVQLRSRRLELLGRASPHCHCSTTSL
. ::. . : . .. : . : .: :.: ::: .:: : ::
NP_001 HRGPGDEDQ-EEETQGQEEGDEGEPRDHPA---------SERTPLLG-SSPTLPTSFGSL
280 290 300 310 320
420
pF1KE4 EAE---YTTVSSAPPEAPGQ
. :. :: .:
NP_001 APAPLVFPGPSTDPPLSPPSSPVILV
330 340 350
429 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 02:08:29 2016 done: Tue Nov 8 02:08:30 2016
Total Scan time: 9.930 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]