Result of FASTA (ccds) for
pFN21AE4082
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4082, 429 aa
1>>>pF1KE4082 429 - 429 aa - 429 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2271+/-0.000822; mu= 10.5639+/- 0.050
mean_var=160.6200+/-32.343, 0's: 0 Z-trim(114.2): 65 B-trim: 87 in 2/50
Lambda= 0.101199
statistics sampled from 14674 (14740) to 14674 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.453), width: 16
Scan time: 3.140
The best scores are: opt bits E(32554)
CCDS42475.1 ZNRF4 gene_id:148066|Hs108|chr19 ( 429) 2998 449.2 3.5e-126
CCDS3146.1 RNF13 gene_id:11342|Hs108|chr3 ( 381) 753 121.4 1.5e-27
CCDS11060.1 RNF167 gene_id:26001|Hs108|chr17 ( 350) 735 118.8 8.7e-27
CCDS82040.1 RNF167 gene_id:26001|Hs108|chr17 ( 315) 704 114.2 1.9e-25
>>CCDS42475.1 ZNRF4 gene_id:148066|Hs108|chr19 (429 aa)
initn: 2998 init1: 2998 opt: 2998 Z-score: 2378.8 bits: 449.2 E(32554): 3.5e-126
Smith-Waterman score: 2998; 99.5% identity (100.0% similar) in 429 aa overlap (1-429:1-429)
10 20 30 40 50 60
pF1KE4 MPLCRPEHLMPRASRVPVAASLPLSHAVIPTQLPSRPGHRPPGRPRRCPKASCLPPPVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MPLCRPEHLMPRASRVPVAASLPLSHAVIPTQLPSRPGHRPPGRPRRCPKASCLPPPVGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SSTQTAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSSSVDFADLPALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SSTQTAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSSSVDFADLPALF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 GVPLAPEGIRGYLMEVKPANACHPIEAPRLGNRSLGSIALIRRYDCTFDLKVLNAQRAGF
::::::::::::::::::::::::::::::::::::.:.:::::::::::::::::::::
CCDS42 GVPLAPEGIRGYLMEVKPANACHPIEAPRLGNRSLGAIVLIRRYDCTFDLKVLNAQRAGF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 EAAIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGCNKSAHALLLPDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EAAIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGCNKSAHALLLPDD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 PPCHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRPVKTSTCQKAQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PPCHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRPVKTSTCQKAQVR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 TFTWHNDLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQSVAATED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 TFTWHNDLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQSVAATED
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE4 SFDSTTYSFRDEDPSLPGHRPPIWAIQVQLRSRRLELLGRASPHCHCSTTSLEAEYTTVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SFDSTTYSFRDEDPSLPGHRPPIWAIQVQLRSRRLELLGRASPHCHCSTTSLEAEYTTVS
370 380 390 400 410 420
pF1KE4 SAPPEAPGQ
:::::::::
CCDS42 SAPPEAPGQ
>>CCDS3146.1 RNF13 gene_id:11342|Hs108|chr3 (381 aa)
initn: 615 init1: 276 opt: 753 Z-score: 608.1 bits: 121.4 E(32554): 1.5e-27
Smith-Waterman score: 753; 40.8% identity (69.0% similar) in 316 aa overlap (80-389:18-321)
50 60 70 80 90 100
pF1KE4 KASCLPPPVGPSSTQTAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSS
...:. . :.:: :..: . : .:.:
CCDS31 MLLSIGMLMLSATQVYTILTVQLFAFLNLL--PVEADILAYNFENAS
10 20 30 40
110 120 130 140 150 160
pF1KE4 SVDFADLPALFGVPLAPEGIRGYLMEVKPANACHPIEAPRLGNRSLGS-IALIRRYDCTF
.. : :::: :: : ::..:.:.. :: :::.:: : . . : :. :.:::: ::.:
CCDS31 QT-FDDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNF
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 DLKVLNAQRAGFEAAIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGC
:.:::::::::..::::::: ::::.:: .. .: :::::..:.....:. .
CCDS31 DIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTY
110 120 130 140 150 160
230 240 250 260 270 280
pF1KE4 NKSAHALLLPDDPPCHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRP
.:..: .:.:. . : : . .: : :.: :.. . . .: .:
CCDS31 EKGGHLILVPEFSLPLEYYLIPFLII---VGICLILIV-IFMITKFVQDRHRA---RRNR
170 180 190 200 210
290 300 310 320 330 340
pF1KE4 VKTSTCQKAQVRTFTWHN--DLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRR
.. . .: :. : . :.:::::::::.::.:.::::::.:::::.:::.... ..
CCDS31 LRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKT-KK
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE4 SCPVCKQSVAATEDSFDSTTYSFRDEDPSLPGHRP---PIWAIQVQLRSRRLELLGRASP
.::::::.:. .. . :: : : ..:. . : : :. ....:
CCDS31 TCPVCKQKVVPSQGDSDSDTDSSQEENE-VTEHTPLLRPLASVSAQSFGALSESRSHQNM
280 290 300 310 320 330
410 420
pF1KE4 HCHCSTTSLEAEYTTVSSAPPEAPGQ
CCDS31 TESSDYEEDDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV
340 350 360 370 380
>>CCDS11060.1 RNF167 gene_id:26001|Hs108|chr17 (350 aa)
initn: 747 init1: 300 opt: 735 Z-score: 594.4 bits: 118.8 E(32554): 8.7e-27
Smith-Waterman score: 785; 39.7% identity (67.5% similar) in 348 aa overlap (95-427:21-342)
70 80 90 100 110 120
pF1KE4 TAKRVTMGWPRPGRALVAVKALLVLSLLQVPAQAVVRAVLEDNSSSVDFADLPALFGVPL
:.....::. :...:.::::::::::. :
CCDS11 MHPAAFPLPVVVAAVLWGAAPTRGLIRAT-SDHNASMDFADLPALFGATL
10 20 30 40
130 140 150 160 170 180
pF1KE4 APEGIRGYLMEVKPANACHPIEAPRLGNRSLGS--IALIRRYDCTFDLKVLNAQRAGFEA
. ::..:.:.:..: ::: :: : . . :: :::.::.::.:::::::::.::. :
CCDS11 SQEGLQGFLVEAHPDNACSPIAPPPPAPVN-GSVFIALLRRFDCNFDLKVLNAQKAGYGA
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE4 AIVHNVHSDDLVSMTHVYEDLRGQIAIPSVFVSEAASQDLRVILGCNKSAHALLLPDDPP
:.::::.:..:..:. :... :: :::::..: .:. ::... .:.:..::.::.
CCDS11 AVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNT-
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE4 CHDLGCHPVLTVSWVLGCTLALVVSAFFVLNHLWLWAQACCSHRRPVKTSTCQKAQVRTF
:: . .. . ..: :.:...: .. : .::. .. . : :.. .
CCDS11 -FPLGYY-LIPFTGIVG-LLVLAMGAVMI--------ARCIQHRKRLQRNRLTKEQLKQI
170 180 190 200 210
310 320 330 340 350
pF1KE4 TWHN-------DLCAICLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQSV
:. :.:::::::::.::.:..:::.:.:: .:.:::..:. :..::.::: :
CCDS11 PTHDYQKGDQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQT-RKTCPICKQPV
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE4 ---AATEDSFDSTTYSFRDEDPSLPGHRPPIWAIQVQLRSRRLELLGRASPHCHCSTTSL
. ::. . : . .. : . : .: :.: ::: .:: : ::
CCDS11 HRGPGDEDQ-EEETQGQEEGDEGEPRDHPA---------SERTPLLG-SSPTLPTSFGSL
280 290 300 310 320
420
pF1KE4 EAE---YTTVSSAPPEAPGQ
. :. :: .:
CCDS11 APAPLVFPGPSTDPPLSPPSSPVILV
330 340 350
>>CCDS82040.1 RNF167 gene_id:26001|Hs108|chr17 (315 aa)
initn: 731 init1: 300 opt: 704 Z-score: 570.5 bits: 114.2 E(32554): 1.9e-25
Smith-Waterman score: 754; 40.1% identity (66.6% similar) in 332 aa overlap (111-427:1-307)
90 100 110 120 130 140
pF1KE4 VAVKALLVLSLLQVPAQAVVRAVLEDNSSSVDFADLPALFGVPLAPEGIRGYLMEVKPAN
.::::::::::. :. ::..:.:.:..: :
CCDS82 MDFADLPALFGATLSQEGLQGFLVEAHPDN
10 20 30
150 160 170 180 190
pF1KE4 ACHPIEAPRLGNRSLGS--IALIRRYDCTFDLKVLNAQRAGFEAAIVHNVHSDDLVSMTH
:: :: : . . :: :::.::.::.:::::::::.::. ::.::::.:..:..:.
CCDS82 ACSPIAPPPPAPVN-GSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVW
40 50 60 70 80
200 210 220 230 240 250
pF1KE4 VYEDLRGQIAIPSVFVSEAASQDLRVILGCNKSAHALLLPDDPPCHDLGCHPVLTVSWVL
:... :: :::::..: .:. ::... .:.:..::.::. :: . .. . ..
CCDS82 NSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNT--FPLG-YYLIPFTGIV
90 100 110 120 130 140
260 270 280 290 300 310
pF1KE4 GCTLALVVSAFFVLNHLWLWAQACCSHRRPVKTSTCQKAQVRTFTWHN-------DLCAI
: :.:...: .. : .::. .. . : :.. . :. :.:::
CCDS82 G-LLVLAMGAVMIAR--------CIQHRKRLQRNRLTKEQLKQIPTHDYQKGDQYDVCAI
150 160 170 180 190
320 330 340 350 360
pF1KE4 CLDEYEEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQSV---AATEDSFDSTTYS
::::::.::.:..:::.:.:: .:.:::..:. :..::.::: : . ::. . : .
CCDS82 CLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQT-RKTCPICKQPVHRGPGDEDQ-EEETQG
200 210 220 230 240 250
370 380 390 400 410 420
pF1KE4 FRDEDPSLPGHRPPIWAIQVQLRSRRLELLGRASPHCHCSTTSLEAE---YTTVSSAPPE
.. : . : .: :.: ::: .:: : :: . :. ::
CCDS82 QEEGDEGEPRDHPA---------SERTPLLG-SSPTLPTSFGSLAPAPLVFPGPSTDPPL
260 270 280 290 300
pF1KE4 APGQ
.:
CCDS82 SPPSSPVILV
310
429 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 02:08:28 2016 done: Tue Nov 8 02:08:28 2016
Total Scan time: 3.140 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]