Result of FASTA (ccds) for
pFN21AE4079
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4079, 419 aa
1>>>pF1KE4079 419 - 419 aa - 419 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6593+/-0.000836; mu= 15.1259+/- 0.050
mean_var=70.0325+/-14.188, 0's: 0 Z-trim(106.7): 27 B-trim: 0 in 0/54
Lambda= 0.153258
statistics sampled from 9119 (9140) to 9119 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.281), width: 16
Scan time: 2.900
The best scores are: opt bits E(32554)
CCDS4821.1 KCTD20 gene_id:222658|Hs108|chr6 ( 419) 2865 642.7 2e-184
CCDS69097.1 KCTD20 gene_id:222658|Hs108|chr6 ( 274) 1887 426.3 1.7e-119
CCDS76388.1 BTBD10 gene_id:84280|Hs108|chr11 ( 427) 1605 364.1 1.5e-100
CCDS7811.1 BTBD10 gene_id:84280|Hs108|chr11 ( 475) 1605 364.1 1.6e-100
CCDS73261.1 BTBD10 gene_id:84280|Hs108|chr11 ( 483) 1605 364.1 1.6e-100
CCDS69096.1 KCTD20 gene_id:222658|Hs108|chr6 ( 253) 1360 309.8 1.9e-84
>>CCDS4821.1 KCTD20 gene_id:222658|Hs108|chr6 (419 aa)
initn: 2865 init1: 2865 opt: 2865 Z-score: 3424.5 bits: 642.7 E(32554): 2e-184
Smith-Waterman score: 2865; 100.0% identity (100.0% similar) in 419 aa overlap (1-419:1-419)
10 20 30 40 50 60
pF1KE4 MNVHRGSDSDRLLRQEASCLVDDTLAVAQEKEANSLASSGPHNLTYPLGPRNEDLSLDYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 MNVHRGSDSDRLLRQEASCLVDDTLAVAQEKEANSLASSGPHNLTYPLGPRNEDLSLDYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SQPANLQFPHIMPLAEDIKGSCFQSGNKRNHEPFIAPERFGNSSVGFGSNSHSQAPEKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 SQPANLQFPHIMPLAEDIKGSCFQSGNKRNHEPFIAPERFGNSSVGFGSNSHSQAPEKVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISATVFRTVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 LLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISATVFRTVLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 YYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFDHYLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 YYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFDHYLE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 ELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE4 NRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 NRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEG
310 320 330 340 350 360
370 380 390 400 410
pF1KE4 KSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMHHPPQVDELDRLNAPLSQMASNDFQD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 KSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMHHPPQVDELDRLNAPLSQMASNDFQD
370 380 390 400 410
>>CCDS69097.1 KCTD20 gene_id:222658|Hs108|chr6 (274 aa)
initn: 1887 init1: 1887 opt: 1887 Z-score: 2258.7 bits: 426.3 E(32554): 1.7e-119
Smith-Waterman score: 1887; 100.0% identity (100.0% similar) in 274 aa overlap (146-419:1-274)
120 130 140 150 160 170
pF1KE4 PEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISATVF
::::::::::::::::::::::::::::::
CCDS69 MFGPGREYNFTRPNEKGEYEIAEGISATVF
10 20 30
180 190 200 210 220 230
pF1KE4 RTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 RTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQF
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE4 DHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 DHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRF
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE4 FKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 FKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSW
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE4 EKEEGKSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMHHPPQVDELDRLNAPLSQMASN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 EKEEGKSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMHHPPQVDELDRLNAPLSQMASN
220 230 240 250 260 270
pF1KE4 DFQD
::::
CCDS69 DFQD
>>CCDS76388.1 BTBD10 gene_id:84280|Hs108|chr11 (427 aa)
initn: 1616 init1: 1594 opt: 1605 Z-score: 1918.8 bits: 364.1 E(32554): 1.5e-100
Smith-Waterman score: 1618; 60.0% identity (80.0% similar) in 415 aa overlap (5-419:24-419)
10 20 30 40
pF1KE4 MNVHRGSDSDRLLRQEASCLVDDTLAVAQEKEANSLASSGP
: :. .: : . :. . : . :.. .
CCDS76 MSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHH----VEREKD
10 20 30 40 50
50 60 70 80 90 100
pF1KE4 HNLTYPLGPRNEDLSLDYASQPANLQFPHIMPLAEDIKGSCFQSGNKRNHEPFIAPERFG
:. . : .:: . : . . . :. . . . : ::: .:. :. .
CCDS76 HSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSD--GSCKTAGEMV----FV----YE
60 70 80 90 100
110 120 130 140 150 160
pF1KE4 NSSVGFGSNSHSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEK
:.. : . .. :.:::.::.:::::.:.::::.:.:::::::: :::.::::::::
CCDS76 NAKEG---ARNIRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEK
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE4 GEYEIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSA
::::.::::..::::..::::::::: ::::::::.::..::::::.:...::.:.::::
CCDS76 GEYEVAEGIGSTVFRAILDYYKTGIIRCPDGISIPELREACDYLCISFEYSTIKCRDLSA
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE4 LLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGE
:.::::::::..::. ::::.:::.::. :..::::::::::::.: :::::..:: :::
CCDS76 LMHELSNDGARRQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGE
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE4 EYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEV
:::::.::.::::::::::::::::.::::::::.::.::::::: :::.:.::::: ::
CCDS76 EYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEV
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE4 IYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMHHPPQVDE
::::::::::.::::::::::::::::::.:::.:::.::. :. .:: ..:: :::::
CCDS76 IYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDE
350 360 370 380 390 400
410
pF1KE4 LDRLNAPLSQMASNDFQD
:: : :. ..:. :
CCDS76 LDIL--PIHPPSGNSDLDPDAQNPML
410 420
>>CCDS7811.1 BTBD10 gene_id:84280|Hs108|chr11 (475 aa)
initn: 1616 init1: 1594 opt: 1605 Z-score: 1918.0 bits: 364.1 E(32554): 1.6e-100
Smith-Waterman score: 1618; 60.0% identity (80.0% similar) in 415 aa overlap (5-419:72-467)
10 20 30
pF1KE4 MNVHRGSDSDRLLRQEASCLVDDTLAVAQEKEAN
: :. .: : . :. . : . :..
CCDS78 GGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHH---
50 60 70 80 90
40 50 60 70 80 90
pF1KE4 SLASSGPHNLTYPLGPRNEDLSLDYASQPANLQFPHIMPLAEDIKGSCFQSGNKRNHEPF
. :. . : .:: . : . . . :. . . . : ::: .:. :
CCDS78 -VEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSD--GSCKTAGEMV----F
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE4 IAPERFGNSSVGFGSNSHSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYN
. . :.. : . .. :.:::.::.:::::.:.::::.:.:::::::: :::.:
CCDS78 V----YENAKEG---ARNIRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHN
160 170 180 190 200
160 170 180 190 200 210
pF1KE4 FTRPNEKGEYEIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTI
:::::::::::.::::..::::..::::::::: ::::::::.::..::::::.:...::
CCDS78 FTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCPDGISIPELREACDYLCISFEYSTI
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE4 RCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDED
.:.:::::.::::::::..::. ::::.:::.::. :..::::::::::::.: :::::.
CCDS78 KCRDLSALMHELSNDGARRQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEE
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE4 HPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRR
.:: ::::::::.::.::::::::::::::::.::::::::.::.::::::: :::.:.:
CCDS78 YPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKR
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE4 PGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMH
:::: ::::::::::::.::::::::::::::::::.:::.:::.::. :. .:: ..::
CCDS78 PGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMH
390 400 410 420 430 440
400 410
pF1KE4 HPPQVDELDRLNAPLSQMASNDFQD
::::::: : :. ..:. :
CCDS78 PTPQVDELDIL--PIHPPSGNSDLDPDAQNPML
450 460 470
>>CCDS73261.1 BTBD10 gene_id:84280|Hs108|chr11 (483 aa)
initn: 1644 init1: 1594 opt: 1605 Z-score: 1917.9 bits: 364.1 E(32554): 1.6e-100
Smith-Waterman score: 1618; 60.0% identity (80.0% similar) in 415 aa overlap (5-419:80-475)
10 20 30
pF1KE4 MNVHRGSDSDRLLRQEASCLVDDTLAVAQEKEAN
: :. .: : . :. . : . :..
CCDS73 GGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHH---
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE4 SLASSGPHNLTYPLGPRNEDLSLDYASQPANLQFPHIMPLAEDIKGSCFQSGNKRNHEPF
. :. . : .:: . : . . . :. . . . : ::: .:. :
CCDS73 -VEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSD--GSCKTAGEMV----F
110 120 130 140 150
100 110 120 130 140 150
pF1KE4 IAPERFGNSSVGFGSNSHSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYN
. . :.. : . .. :.:::.::.:::::.:.::::.:.:::::::: :::.:
CCDS73 V----YENAKEG---ARNIRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHN
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE4 FTRPNEKGEYEIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTI
:::::::::::.::::..::::..::::::::: ::::::::.::..::::::.:...::
CCDS73 FTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCPDGISIPELREACDYLCISFEYSTI
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE4 RCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDED
.:.:::::.::::::::..::. ::::.:::.::. :..::::::::::::.: :::::.
CCDS73 KCRDLSALMHELSNDGARRQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEE
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE4 HPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRR
.:: ::::::::.::.::::::::::::::::.::::::::.::.::::::: :::.:.:
CCDS73 YPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKR
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE4 PGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMH
:::: ::::::::::::.::::::::::::::::::.:::.:::.::. :. .:: ..::
CCDS73 PGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMH
400 410 420 430 440 450
400 410
pF1KE4 HPPQVDELDRLNAPLSQMASNDFQD
::::::: : :. ..:. :
CCDS73 PTPQVDELDIL--PIHPPSGNSDLDPDAQNPML
460 470 480
>>CCDS69096.1 KCTD20 gene_id:222658|Hs108|chr6 (253 aa)
initn: 1695 init1: 1360 opt: 1360 Z-score: 1629.5 bits: 309.8 E(32554): 1.9e-84
Smith-Waterman score: 1367; 60.1% identity (60.4% similar) in 419 aa overlap (1-419:1-253)
10 20 30 40 50 60
pF1KE4 MNVHRGSDSDRLLRQEASCLVDDTLAVAQEKEANSLASSGPHNLTYPLGPRNEDLSLDYA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 MNVHRGSDSDRLLRQEASCLVDDTLAVAQEKEANSLASSGPHNLTYPLGPRNE-------
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 SQPANLQFPHIMPLAEDIKGSCFQSGNKRNHEPFIAPERFGNSSVGFGSNSHSQAPEKVT
CCDS69 ------------------------------------------------------------
130 140 150 160 170 180
pF1KE4 LLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISATVFRTVLD
CCDS69 ------------------------------------------------------------
190 200 210 220 230 240
pF1KE4 YYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFDHYLE
.::::::::::::::::::::
CCDS69 ---------------------------------------GALLHELSNDGAHKQFDHYLE
60 70
250 260 270 280 290 300
pF1KE4 ELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 ELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIE
80 90 100 110 120 130
310 320 330 340 350 360
pF1KE4 NRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 NRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEG
140 150 160 170 180 190
370 380 390 400 410
pF1KE4 KSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMHHPPQVDELDRLNAPLSQMASNDFQD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 KSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMHHPPQVDELDRLNAPLSQMASNDFQD
200 210 220 230 240 250
419 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:39:11 2016 done: Sun Nov 6 03:39:11 2016
Total Scan time: 2.900 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]