Result of FASTA (omim) for
pFN21AE4075
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4075, 358 aa
1>>>pF1KE4075 358 - 358 aa - 358 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0744+/-0.000396; mu= 16.3066+/- 0.025
mean_var=171.8642+/-35.274, 0's: 0 Z-trim(118.0): 178 B-trim: 1551 in 2/53
Lambda= 0.097832
statistics sampled from 30409 (30605) to 30409 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.359), width: 16
Scan time: 8.490
The best scores are: opt bits E(85289)
NP_912730 (OMIM: 606474) tripartite motif-containi ( 358) 2413 352.5 8.4e-97
NP_908974 (OMIM: 606469) tripartite motif-containi ( 452) 1539 229.3 1.3e-59
XP_011515918 (OMIM: 606469) PREDICTED: tripartite ( 452) 1539 229.3 1.3e-59
XP_011515917 (OMIM: 606469) PREDICTED: tripartite ( 540) 1539 229.4 1.5e-59
NP_149047 (OMIM: 606469) tripartite motif-containi ( 540) 1539 229.4 1.5e-59
XP_011515916 (OMIM: 606469) PREDICTED: tripartite ( 548) 1539 229.4 1.5e-59
XP_011515915 (OMIM: 606469) PREDICTED: tripartite ( 548) 1539 229.4 1.5e-59
NP_908973 (OMIM: 606469) tripartite motif-containi ( 548) 1539 229.4 1.5e-59
XP_005251373 (OMIM: 606469) PREDICTED: tripartite ( 547) 1532 228.4 2.9e-59
NP_115977 (OMIM: 606131) E3 ubiquitin-protein liga ( 353) 1437 214.7 2.4e-55
XP_016858048 (OMIM: 606131) PREDICTED: E3 ubiquiti ( 379) 1437 214.8 2.5e-55
NP_115935 (OMIM: 606474) tripartite motif-containi ( 400) 1218 183.9 5.3e-46
XP_016869397 (OMIM: 606469) PREDICTED: tripartite ( 479) 1187 179.6 1.2e-44
NP_908975 (OMIM: 606469) tripartite motif-containi ( 241) 1107 167.9 2e-41
XP_016869398 (OMIM: 606469) PREDICTED: tripartite ( 426) 891 137.8 4.3e-32
XP_011515919 (OMIM: 606469) PREDICTED: tripartite ( 426) 891 137.8 4.3e-32
NP_150594 (OMIM: 605493) tripartite motif-containi ( 744) 374 65.2 5.5e-10
XP_016872587 (OMIM: 605493) PREDICTED: tripartite ( 744) 374 65.2 5.5e-10
XP_011518146 (OMIM: 605493) PREDICTED: tripartite ( 744) 374 65.2 5.5e-10
NP_006449 (OMIM: 605493) tripartite motif-containi ( 744) 374 65.2 5.5e-10
NP_001234935 (OMIM: 605493) tripartite motif-conta ( 744) 374 65.2 5.5e-10
XP_016865112 (OMIM: 609317) PREDICTED: E3 ubiquiti ( 529) 367 64.0 9e-10
NP_001287681 (OMIM: 609317) E3 ubiquitin-protein l ( 573) 367 64.0 9.4e-10
NP_001287688 (OMIM: 609317) E3 ubiquitin-protein l ( 716) 367 64.1 1.1e-09
NP_061170 (OMIM: 609317) E3 ubiquitin-protein liga ( 728) 367 64.2 1.1e-09
XP_016865111 (OMIM: 609317) PREDICTED: E3 ubiquiti ( 733) 367 64.2 1.1e-09
XP_016865110 (OMIM: 609317) PREDICTED: E3 ubiquiti ( 745) 367 64.2 1.1e-09
NP_001269308 (OMIM: 600986) tripartite motif-conta ( 551) 356 62.4 2.7e-09
NP_001269307 (OMIM: 600986) tripartite motif-conta ( 633) 356 62.5 2.9e-09
NP_001243528 (OMIM: 600986) tripartite motif-conta ( 736) 356 62.6 3.2e-09
NP_001243530 (OMIM: 600986) tripartite motif-conta ( 746) 356 62.6 3.2e-09
XP_016857882 (OMIM: 600986) PREDICTED: tripartite ( 746) 356 62.6 3.2e-09
NP_079334 (OMIM: 600986) tripartite motif-containi ( 759) 356 62.6 3.3e-09
XP_011508304 (OMIM: 600986) PREDICTED: tripartite ( 788) 356 62.6 3.3e-09
NP_001180208 (OMIM: 189960,300000,300552) E3 ubiqu ( 489) 348 61.2 5.5e-09
XP_016885031 (OMIM: 189960,300000,300552) PREDICTE ( 489) 348 61.2 5.5e-09
XP_016885029 (OMIM: 189960,300000,300552) PREDICTE ( 552) 348 61.3 5.9e-09
XP_016885025 (OMIM: 189960,300000,300552) PREDICTE ( 667) 348 61.4 6.6e-09
NP_000372 (OMIM: 189960,300000,300552) E3 ubiquiti ( 667) 348 61.4 6.6e-09
NP_001180206 (OMIM: 189960,300000,300552) E3 ubiqu ( 667) 348 61.4 6.6e-09
NP_001092094 (OMIM: 189960,300000,300552) E3 ubiqu ( 667) 348 61.4 6.6e-09
NP_150632 (OMIM: 189960,300000,300552) E3 ubiquiti ( 667) 348 61.4 6.6e-09
NP_001287818 (OMIM: 610584) tripartite motif-conta ( 721) 326 58.4 6e-08
XP_011542494 (OMIM: 610584) PREDICTED: tripartite ( 781) 326 58.4 6.3e-08
NP_001004342 (OMIM: 610584) tripartite motif-conta ( 783) 326 58.4 6.3e-08
XP_016856812 (OMIM: 610584) PREDICTED: tripartite ( 854) 326 58.5 6.6e-08
XP_016884728 (OMIM: 300204,300928) PREDICTED: prob ( 685) 320 57.5 1e-07
NP_438112 (OMIM: 300204,300928) probable E3 ubiqui ( 705) 320 57.5 1.1e-07
XP_005262119 (OMIM: 300204,300928) PREDICTED: prob ( 715) 320 57.5 1.1e-07
NP_036348 (OMIM: 300204,300928) probable E3 ubiqui ( 735) 320 57.5 1.1e-07
>>NP_912730 (OMIM: 606474) tripartite motif-containing p (358 aa)
initn: 2413 init1: 2413 opt: 2413 Z-score: 1858.9 bits: 352.5 E(85289): 8.4e-97
Smith-Waterman score: 2413; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KE4 MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_912 MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_912 LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_912 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_912 LVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 EKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_912 EKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAG
250 260 270 280 290 300
310 320 330 340 350
pF1KE4 RPEPGYESMEQFTVRVEHVAEMLRTIDFQPGASGEEEEVAPDGEEGSAGPEEERPDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_912 RPEPGYESMEQFTVRVEHVAEMLRTIDFQPGASGEEEEVAPDGEEGSAGPEEERPDGP
310 320 330 340 350
>>NP_908974 (OMIM: 606469) tripartite motif-containing p (452 aa)
initn: 1519 init1: 887 opt: 1539 Z-score: 1191.2 bits: 229.3 E(85289): 1.3e-59
Smith-Waterman score: 1539; 63.8% identity (85.9% similar) in 354 aa overlap (1-351:1-352)
10 20 30 40 50 60
pF1KE4 MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP
:. ....: . . ..:::::::::::::::::.:::::::::::::::::.:.::::::
NP_908 MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA
.::.::..:::::::::::::::::::::::::::::::::::::::::.:: ..:.
NP_908 YLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRP-EKKS
70 80 90 100 110
130 140 150 160 170 180
pF1KE4 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAM
.: ::::::::.::::::.::::::::::::::::::.:::: ...:::::::::::.
NP_908 DQP-MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 LVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQE
::..:::::.::.:.:..:.:::. :.::: : ..:. : ..:::::.:. :...: ::
NP_908 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 EKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAG
:::..::.::..:.:::: ::::::.:: :.::.::..::.:: :..:.. ::.
NP_908 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
310 320 330 340 350
pF1KE4 RPEPGYESMEQFTVRVEHVAEMLRTIDFQPGASGEEEEVAPDGE---EGSAGPEEERPDG
. : :::.:..::: ... ...: ::: :::: . .:: :: .: :
NP_908 KIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEEEEGGEGEKEGEGEVGGEAVEVEE
300 310 320 330 340 350
pF1KE4 P
NP_908 VENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQIGFEAP
360 370 380 390 400 410
>>XP_011515918 (OMIM: 606469) PREDICTED: tripartite moti (452 aa)
initn: 1519 init1: 887 opt: 1539 Z-score: 1191.2 bits: 229.3 E(85289): 1.3e-59
Smith-Waterman score: 1539; 63.8% identity (85.9% similar) in 354 aa overlap (1-351:1-352)
10 20 30 40 50 60
pF1KE4 MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP
:. ....: . . ..:::::::::::::::::.:::::::::::::::::.:.::::::
XP_011 MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA
.::.::..:::::::::::::::::::::::::::::::::::::::::.:: ..:.
XP_011 YLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRP-EKKS
70 80 90 100 110
130 140 150 160 170 180
pF1KE4 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAM
.: ::::::::.::::::.::::::::::::::::::.:::: ...:::::::::::.
XP_011 DQP-MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 LVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQE
::..:::::.::.:.:..:.:::. :.::: : ..:. : ..:::::.:. :...: ::
XP_011 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 EKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAG
:::..::.::..:.:::: ::::::.:: :.::.::..::.:: :..:.. ::.
XP_011 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
310 320 330 340 350
pF1KE4 RPEPGYESMEQFTVRVEHVAEMLRTIDFQPGASGEEEEVAPDGE---EGSAGPEEERPDG
. : :::.:..::: ... ...: ::: :::: . .:: :: .: :
XP_011 KIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEEEEGGEGEKEGEGEVGGEAVEVEE
300 310 320 330 340 350
pF1KE4 P
XP_011 VENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQIGFEAP
360 370 380 390 400 410
>>XP_011515917 (OMIM: 606469) PREDICTED: tripartite moti (540 aa)
initn: 1519 init1: 887 opt: 1539 Z-score: 1190.3 bits: 229.4 E(85289): 1.5e-59
Smith-Waterman score: 1539; 63.8% identity (85.9% similar) in 354 aa overlap (1-351:1-352)
10 20 30 40 50 60
pF1KE4 MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP
:. ....: . . ..:::::::::::::::::.:::::::::::::::::.:.::::::
XP_011 MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA
.::.::..:::::::::::::::::::::::::::::::::::::::::.:: ..:.
XP_011 YLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRP-EKKS
70 80 90 100 110
130 140 150 160 170 180
pF1KE4 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAM
.: ::::::::.::::::.::::::::::::::::::.:::: ...:::::::::::.
XP_011 DQP-MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 LVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQE
::..:::::.::.:.:..:.:::. :.::: : ..:. : ..:::::.:. :...: ::
XP_011 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 EKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAG
:::..::.::..:.:::: ::::::.:: :.::.::..::.:: :..:.. ::.
XP_011 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
310 320 330 340 350
pF1KE4 RPEPGYESMEQFTVRVEHVAEMLRTIDFQPGASGEEEEVAPDGE---EGSAGPEEERPDG
. : :::.:..::: ... ...: ::: :::: . .:: :: .: :
XP_011 KIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEEEEGGEGEKEGEGEVGGEAVEVEE
300 310 320 330 340 350
pF1KE4 P
XP_011 VENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQGEVVPT
360 370 380 390 400 410
>>NP_149047 (OMIM: 606469) tripartite motif-containing p (540 aa)
initn: 1519 init1: 887 opt: 1539 Z-score: 1190.3 bits: 229.4 E(85289): 1.5e-59
Smith-Waterman score: 1539; 63.8% identity (85.9% similar) in 354 aa overlap (1-351:1-352)
10 20 30 40 50 60
pF1KE4 MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP
:. ....: . . ..:::::::::::::::::.:::::::::::::::::.:.::::::
NP_149 MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA
.::.::..:::::::::::::::::::::::::::::::::::::::::.:: ..:.
NP_149 YLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRP-EKKS
70 80 90 100 110
130 140 150 160 170 180
pF1KE4 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAM
.: ::::::::.::::::.::::::::::::::::::.:::: ...:::::::::::.
NP_149 DQP-MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 LVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQE
::..:::::.::.:.:..:.:::. :.::: : ..:. : ..:::::.:. :...: ::
NP_149 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 EKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAG
:::..::.::..:.:::: ::::::.:: :.::.::..::.:: :..:.. ::.
NP_149 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
310 320 330 340 350
pF1KE4 RPEPGYESMEQFTVRVEHVAEMLRTIDFQPGASGEEEEVAPDGE---EGSAGPEEERPDG
. : :::.:..::: ... ...: ::: :::: . .:: :: .: :
NP_149 KIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEEEEGGEGEKEGEGEVGGEAVEVEE
300 310 320 330 340 350
pF1KE4 P
NP_149 VENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQGEVVPT
360 370 380 390 400 410
>>XP_011515916 (OMIM: 606469) PREDICTED: tripartite moti (548 aa)
initn: 1519 init1: 887 opt: 1539 Z-score: 1190.3 bits: 229.4 E(85289): 1.5e-59
Smith-Waterman score: 1539; 63.8% identity (85.9% similar) in 354 aa overlap (1-351:1-352)
10 20 30 40 50 60
pF1KE4 MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP
:. ....: . . ..:::::::::::::::::.:::::::::::::::::.:.::::::
XP_011 MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA
.::.::..:::::::::::::::::::::::::::::::::::::::::.:: ..:.
XP_011 YLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRP-EKKS
70 80 90 100 110
130 140 150 160 170 180
pF1KE4 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAM
.: ::::::::.::::::.::::::::::::::::::.:::: ...:::::::::::.
XP_011 DQP-MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 LVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQE
::..:::::.::.:.:..:.:::. :.::: : ..:. : ..:::::.:. :...: ::
XP_011 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 EKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAG
:::..::.::..:.:::: ::::::.:: :.::.::..::.:: :..:.. ::.
XP_011 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
310 320 330 340 350
pF1KE4 RPEPGYESMEQFTVRVEHVAEMLRTIDFQPGASGEEEEVAPDGE---EGSAGPEEERPDG
. : :::.:..::: ... ...: ::: :::: . .:: :: .: :
XP_011 KIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEEEEGGEGEKEGEGEVGGEAVEVEE
300 310 320 330 340 350
pF1KE4 P
XP_011 VENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQGEVVPT
360 370 380 390 400 410
>>XP_011515915 (OMIM: 606469) PREDICTED: tripartite moti (548 aa)
initn: 1519 init1: 887 opt: 1539 Z-score: 1190.3 bits: 229.4 E(85289): 1.5e-59
Smith-Waterman score: 1539; 63.8% identity (85.9% similar) in 354 aa overlap (1-351:1-352)
10 20 30 40 50 60
pF1KE4 MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP
:. ....: . . ..:::::::::::::::::.:::::::::::::::::.:.::::::
XP_011 MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA
.::.::..:::::::::::::::::::::::::::::::::::::::::.:: ..:.
XP_011 YLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRP-EKKS
70 80 90 100 110
130 140 150 160 170 180
pF1KE4 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAM
.: ::::::::.::::::.::::::::::::::::::.:::: ...:::::::::::.
XP_011 DQP-MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 LVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQE
::..:::::.::.:.:..:.:::. :.::: : ..:. : ..:::::.:. :...: ::
XP_011 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 EKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAG
:::..::.::..:.:::: ::::::.:: :.::.::..::.:: :..:.. ::.
XP_011 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
310 320 330 340 350
pF1KE4 RPEPGYESMEQFTVRVEHVAEMLRTIDFQPGASGEEEEVAPDGE---EGSAGPEEERPDG
. : :::.:..::: ... ...: ::: :::: . .:: :: .: :
XP_011 KIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEEEEGGEGEKEGEGEVGGEAVEVEE
300 310 320 330 340 350
pF1KE4 P
XP_011 VENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQGEVVPT
360 370 380 390 400 410
>>NP_908973 (OMIM: 606469) tripartite motif-containing p (548 aa)
initn: 1519 init1: 887 opt: 1539 Z-score: 1190.3 bits: 229.4 E(85289): 1.5e-59
Smith-Waterman score: 1539; 63.8% identity (85.9% similar) in 354 aa overlap (1-351:1-352)
10 20 30 40 50 60
pF1KE4 MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP
:. ....: . . ..:::::::::::::::::.:::::::::::::::::.:.::::::
NP_908 MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA
.::.::..:::::::::::::::::::::::::::::::::::::::::.:: ..:.
NP_908 YLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRP-EKKS
70 80 90 100 110
130 140 150 160 170 180
pF1KE4 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAM
.: ::::::::.::::::.::::::::::::::::::.:::: ...:::::::::::.
NP_908 DQP-MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 LVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQE
::..:::::.::.:.:..:.:::. :.::: : ..:. : ..:::::.:. :...: ::
NP_908 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 EKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAG
:::..::.::..:.:::: ::::::.:: :.::.::..::.:: :..:.. ::.
NP_908 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
310 320 330 340 350
pF1KE4 RPEPGYESMEQFTVRVEHVAEMLRTIDFQPGASGEEEEVAPDGE---EGSAGPEEERPDG
. : :::.:..::: ... ...: ::: :::: . .:: :: .: :
NP_908 KIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEEEEGGEGEKEGEGEVGGEAVEVEE
300 310 320 330 340 350
pF1KE4 P
NP_908 VENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQGEVVPT
360 370 380 390 400 410
>>XP_005251373 (OMIM: 606469) PREDICTED: tripartite moti (547 aa)
initn: 905 init1: 879 opt: 1532 Z-score: 1184.9 bits: 228.4 E(85289): 2.9e-59
Smith-Waterman score: 1532; 63.8% identity (86.2% similar) in 354 aa overlap (1-351:1-351)
10 20 30 40 50 60
pF1KE4 MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP
:. ....: . . ..:::::::::::::::::.:::::::::::::::::.:.::::::
XP_005 MSASLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKA
.::.::..:::::::::::::::::::::::::::::::::::::::::.:: ..:.
XP_005 YLPTRGGTTMASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRP-EKKS
70 80 90 100 110
130 140 150 160 170 180
pF1KE4 EQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAM
.: ::::::::.::::::.::::::::::::::::::.:::: ...:::::::::::.
XP_005 DQP-MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE4 LVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQE
::..:::::.::.:.:..:.:::. :.::: : ..:. : ..:::::.:. :...: ::
XP_005 LVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE4 EKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAG
:::..::.::..:.:::: ::::::.:: :.::.::..::.:: :..:.. ::.
XP_005 EKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME
240 250 260 270 280 290
310 320 330 340 350
pF1KE4 RPEPGYESMEQFTVRVEHVAEMLRTIDFQPGASGEEEEVAPDGE---EGSAGPEEERPDG
. : :::.:..::: ... ...: ::: . :::: . .:: :: .: :
XP_005 KIEHGYENMNHFTVNLNREEKIIREIDFYRDED-EEEEEGGEGEKEGEGEVGGEAVEVEE
300 310 320 330 340 350
pF1KE4 P
XP_005 VENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQGEVVPT
360 370 380 390 400 410
>>NP_115977 (OMIM: 606131) E3 ubiquitin-protein ligase T (353 aa)
initn: 783 init1: 783 opt: 1437 Z-score: 1114.5 bits: 214.7 E(85289): 2.4e-55
Smith-Waterman score: 1437; 60.7% identity (83.5% similar) in 346 aa overlap (10-352:7-350)
10 20 30 40 50 60
pF1KE4 MNFTVGFKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNP
:. :.. :.:::::::::::::::.:::::::::::::::::::.:::.::
NP_115 MDYKSSLIQDGNPMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANP
10 20 30 40 50
70 80 90 100 110
pF1KE4 LWQSRGSTTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQE-SSRPLHSK
: ::::.. ::::::::.:::::..:::::::::::::::::::::::: :::::..
NP_115 YWTSRGSSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQKG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE4 AEQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIA
. : ::.:::.::::::::.:::::::.::::: :: :::::: .... ::.::.. :.
NP_115 S--HPMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCIS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE4 MLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQ
::::::::::..:::.:. .. ..::.. :. :.:.:..: :.:.:.:.:::: ...::
NP_115 MLVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE4 EEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELA
:.::. ...::.:: ..:. :.::::.::::..:: : .: ::.::... ::
NP_115 EKKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE4 GRPEPGYESMEQFTVRVEHVAEMLRTIDFQPGASGEE--EEVAPDGEEGSAGPEEERPDG
:. : :.:.:. ::. .::.:. ::.::: :: :: . ::.. : ::
NP_115 GKTEQGFENMDFFTLDLEHIADALRAIDFGTDEEEEEFIEEEDQEEEESTEGKEEGHQ
300 310 320 330 340 350
pF1KE4 P
358 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:59:28 2016 done: Sun Nov 6 03:59:29 2016
Total Scan time: 8.490 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]