FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4070, 373 aa
  1>>>pF1KE4070 373 - 373 aa - 373 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.8331+/-0.00092; mu= 6.7843+/- 0.056
 mean_var=188.5480+/-39.104, 0's: 0 Z-trim(112.6): 34  B-trim: 42 in 1/50
 Lambda= 0.093404
 statistics sampled from 13328 (13361) to 13328 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.747), E-opt: 0.2 (0.41), width:  16
 Scan time:  2.820

The best scores are:                                      opt bits E(32554)
CCDS9221.1 RNF34 gene_id:80196|Hs108|chr12         ( 373) 2562 357.3 1.3e-98
CCDS31915.1 RNF34 gene_id:80196|Hs108|chr12        ( 372) 2548 355.4 4.7e-98
CCDS73538.1 RNF34 gene_id:80196|Hs108|chr12        ( 180) 1215 175.5 3.3e-44
CCDS11286.1 RFFL gene_id:117584|Hs108|chr17        ( 363)  981 144.2 1.7e-34


>>CCDS9221.1 RNF34 gene_id:80196|Hs108|chr12              (373 aa)
 initn: 2562 init1: 2562 opt: 2562  Z-score: 1884.0  bits: 357.3 E(32554): 1.3e-98
Smith-Waterman score: 2562; 100.0% identity (100.0% similar) in 373 aa overlap (1-373:1-373)

               10        20        30        40        50        60
pF1KE4 MRKAGATSMWASCCGLLNEVMGTGAVRGQQSAFAGATGPFRFTPNPEFSTYPPAATEGPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 MRKAGATSMWASCCGLLNEVMGTGAVRGQQSAFAGATGPFRFTPNPEFSTYPPAATEGPN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 IVCKACGLSFSVFRKKHVCCDCKKDFCSVCSVLQENLRRCSTCHLLQETAFQRPQLMRLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 IVCKACGLSFSVFRKKHVCCDCKKDFCSVCSVLQENLRRCSTCHLLQETAFQRPQLMRLK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 VKDLRQYLILRNIPIDTCREKEDLVDLVLCHHGLGSEDDMDTSSLNSSRSQTSSFFTRSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 VKDLRQYLILRNIPIDTCREKEDLVDLVLCHHGLGSEDDMDTSSLNSSRSQTSSFFTRSF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 FSNYTAPSATMSSFQGELMDGDQTSRSGVPAQVQSEITSANTEDDDDDDDEDDDDEEENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 FSNYTAPSATMSSFQGELMDGDQTSRSGVPAQVQSEITSANTEDDDDDDDEDDDDEEENA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 EDRNPGLSKERVRASLSDLSSLDDVEGMSVRQLKEILARNFVNYSGCCEKWELVEKVNRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 EDRNPGLSKERVRASLSDLSSLDDVEGMSVRQLKEILARNFVNYSGCCEKWELVEKVNRL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE4 YKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPIC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 YKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPIC
              310       320       330       340       350       360

              370   
pF1KE4 RQYVVRAVHVFKS
       :::::::::::::
CCDS92 RQYVVRAVHVFKS
              370   

>>CCDS31915.1 RNF34 gene_id:80196|Hs108|chr12             (372 aa)
 initn: 2548 init1: 2548 opt: 2548  Z-score: 1873.9  bits: 355.4 E(32554): 4.7e-98
Smith-Waterman score: 2548; 100.0% identity (100.0% similar) in 371 aa overlap (3-373:2-372)

               10        20        30        40        50        60
pF1KE4 MRKAGATSMWASCCGLLNEVMGTGAVRGQQSAFAGATGPFRFTPNPEFSTYPPAATEGPN
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31  MKAGATSMWASCCGLLNEVMGTGAVRGQQSAFAGATGPFRFTPNPEFSTYPPAATEGPN
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KE4 IVCKACGLSFSVFRKKHVCCDCKKDFCSVCSVLQENLRRCSTCHLLQETAFQRPQLMRLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 IVCKACGLSFSVFRKKHVCCDCKKDFCSVCSVLQENLRRCSTCHLLQETAFQRPQLMRLK
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KE4 VKDLRQYLILRNIPIDTCREKEDLVDLVLCHHGLGSEDDMDTSSLNSSRSQTSSFFTRSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 VKDLRQYLILRNIPIDTCREKEDLVDLVLCHHGLGSEDDMDTSSLNSSRSQTSSFFTRSF
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KE4 FSNYTAPSATMSSFQGELMDGDQTSRSGVPAQVQSEITSANTEDDDDDDDEDDDDEEENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 FSNYTAPSATMSSFQGELMDGDQTSRSGVPAQVQSEITSANTEDDDDDDDEDDDDEEENA
     180       190       200       210       220       230         

              250       260       270       280       290       300
pF1KE4 EDRNPGLSKERVRASLSDLSSLDDVEGMSVRQLKEILARNFVNYSGCCEKWELVEKVNRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 EDRNPGLSKERVRASLSDLSSLDDVEGMSVRQLKEILARNFVNYSGCCEKWELVEKVNRL
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KE4 YKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPIC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 YKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPIC
     300       310       320       330       340       350         

              370   
pF1KE4 RQYVVRAVHVFKS
       :::::::::::::
CCDS31 RQYVVRAVHVFKS
     360       370  

>>CCDS73538.1 RNF34 gene_id:80196|Hs108|chr12             (180 aa)
 initn: 1215 init1: 1215 opt: 1215  Z-score: 907.2  bits: 175.5 E(32554): 3.3e-44
Smith-Waterman score: 1215; 99.4% identity (100.0% similar) in 179 aa overlap (195-373:2-180)

          170       180       190       200       210       220    
pF1KE4 LNSSRSQTSSFFTRSFFSNYTAPSATMSSFQGELMDGDQTSRSGVPAQVQSEITSANTED
                                     .:::::::::::::::::::::::::::::
CCDS73                              MKGELMDGDQTSRSGVPAQVQSEITSANTED
                                            10        20        30 

          230       240       250       260       270       280    
pF1KE4 DDDDDDEDDDDEEENAEDRNPGLSKERVRASLSDLSSLDDVEGMSVRQLKEILARNFVNY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 DDDDDDEDDDDEEENAEDRNPGLSKERVRASLSDLSSLDDVEGMSVRQLKEILARNFVNY
              40        50        60        70        80        90 

          290       300       310       320       330       340    
pF1KE4 SGCCEKWELVEKVNRLYKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SGCCEKWELVEKVNRLYKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHM
             100       110       120       130       140       150 

          350       360       370   
pF1KE4 VTCTKCGKRMSECPICRQYVVRAVHVFKS
       :::::::::::::::::::::::::::::
CCDS73 VTCTKCGKRMSECPICRQYVVRAVHVFKS
             160       170       180

>>CCDS11286.1 RFFL gene_id:117584|Hs108|chr17             (363 aa)
 initn: 939 init1: 432 opt: 981  Z-score: 732.8  bits: 144.2 E(32554): 1.7e-34
Smith-Waterman score: 981; 43.9% identity (70.0% similar) in 380 aa overlap (9-373:1-363)

               10        20        30         40        50         
pF1KE4 MRKAGATSMWASCCGLLNEVMGTGAVRGQQSAFAGATGP-FRFTPNPEFSTYP-PAATEG
               :::.::. .        . ::        :  ..   :: .:..: :.. : 
CCDS11         MWATCCNWF-------CLDGQPEEVPPPQGARMQAYSNPGYSSFPSPTGLE-
                              10        20        30        40     

       60        70        80        90        100       110       
pF1KE4 PNIVCKACGLSFSVFRKKHVCCDCKKDFCSVCSVLQENLRR-CSTCHLLQETAFQRPQLM
       :.  ::.::  :.   .:..: ::::.:: .::    :  : :  :. .. ::::: .::
CCDS11 PS--CKSCGAHFANTARKQTCLDCKKNFCMTCSSQVGNGPRLCLLCQRFRATAFQREELM
             50        60        70        80        90       100  

       120       130       140       150       160        170      
pF1KE4 RLKVKDLRQYLILRNIPIDTCREKEDLVDLVLCHHGLGSEDDMD-TSSLNSSRSQTSSFF
       ..::::::.:: :..:  . :::::.:: ::: .. . :..:   .:.:. .  . ..:.
CCDS11 KMKVKDLRDYLSLHDISTEMCREKEELVLLVLGQQPVISQEDRTRASTLSPDFPEQQAFL
            110       120       130       140       150       160  

        180       190       200       210        220       230     
pF1KE4 TRSFFSNYTAPSATMSSFQGELMDGDQTSRSGVPAQVQ-SEITSANTEDDDDDDDEDDDD
       :.   :... :..       .: ...  . :  ::::: .. ..... .:...    .. 
CCDS11 TQPH-SSMVPPTSP------NLPSSSAQATSVPPAQVQENQQANGHVSQDQEEPVYLESV
             170             180       190       200       210     

         240       250            260       270       280       290
pF1KE4 EEENAEDRNPGLSKERV-----RASLSDLSSLDDVEGMSVRQLKEILARNFVNYSGCCEK
        .  :::.. ....:       :::::::..:.:.::..:::::::::::::::.:::::
CCDS11 ARVPAEDETQSIDSEDSFVPGRRASLSDLTDLEDIEGLTVRQLKEILARNFVNYKGCCEK
         220       230       240       250       260       270     

              300       310            320       330       340     
pF1KE4 WELVEKVNRLYKENEENQKSY-GERLQ----LQDEEDDSLCRICMDAVIDCVLLECGHMV
       :::.:.:.::::...  :.   : . :    . .  ...::.::::. ::::::::::::
CCDS11 WELMERVTRLYKDQKGLQHLVSGAEDQNGGAVPSGLEENLCKICMDSPIDCVLLECGHMV
         280       290       300       310       320       330     

         350       360       370   
pF1KE4 TCTKCGKRMSECPICRQYVVRAVHVFKS
       :::::::::.:::::::::.::::::.:
CCDS11 TCTKCGKRMNECPICRQYVIRAVHVFRS
         340       350       360   




373 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 16:54:54 2016 done: Mon Nov  7 16:54:55 2016
 Total Scan time:  2.820 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]