Result of FASTA (omim) for
pFN21AE4068
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4068, 355 aa
1>>>pF1KE4068 355 - 355 aa - 355 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4541+/-0.000281; mu= 16.3136+/- 0.018
mean_var=74.5571+/-14.772, 0's: 0 Z-trim(118.7): 42 B-trim: 0 in 0/54
Lambda= 0.148535
statistics sampled from 31839 (31882) to 31839 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.741), E-opt: 0.2 (0.374), width: 16
Scan time: 8.800
The best scores are: opt bits E(85289)
NP_543137 (OMIM: 611659) SPRY domain-containing SO ( 355) 2496 543.7 2.3e-154
NP_001311010 (OMIM: 611659) SPRY domain-containing ( 355) 2496 543.7 2.3e-154
XP_005255730 (OMIM: 611659) PREDICTED: SPRY domain ( 410) 2223 485.2 1e-136
NP_079382 (OMIM: 611657) SPRY domain-containing SO ( 273) 206 52.9 9.8e-07
NP_543138 (OMIM: 611660) SPRY domain-containing SO ( 273) 190 49.5 1.1e-05
NP_001099043 (OMIM: 609112) F-box/SPRY domain-cont ( 286) 170 45.2 0.00021
XP_016862998 (OMIM: 611660) PREDICTED: SPRY domain ( 233) 167 44.5 0.00028
XP_016856812 (OMIM: 610584) PREDICTED: tripartite ( 854) 165 44.4 0.0011
NP_116030 (OMIM: 611658) SPRY domain-containing SO ( 263) 156 42.2 0.0016
NP_001139788 (OMIM: 611658) SPRY domain-containing ( 263) 156 42.2 0.0016
NP_001306599 (OMIM: 611658) SPRY domain-containing ( 263) 156 42.2 0.0016
NP_065901 (OMIM: 614031) ran-binding protein 10 is ( 620) 159 43.1 0.002
XP_005256127 (OMIM: 614031) PREDICTED: ran-binding ( 650) 159 43.1 0.0021
XP_016876438 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 611) 155 42.2 0.0037
XP_016876435 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 706) 155 42.2 0.0041
NP_055978 (OMIM: 606555) E3 ubiquitin-protein liga ( 710) 155 42.2 0.0041
XP_016876434 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 710) 155 42.2 0.0041
XP_016876433 (OMIM: 606555) PREDICTED: E3 ubiquiti ( 732) 155 42.3 0.0042
NP_001287818 (OMIM: 610584) tripartite motif-conta ( 721) 150 41.2 0.0088
XP_011542494 (OMIM: 610584) PREDICTED: tripartite ( 781) 150 41.2 0.0094
NP_001004342 (OMIM: 610584) tripartite motif-conta ( 783) 150 41.2 0.0094
>>NP_543137 (OMIM: 611659) SPRY domain-containing SOCS b (355 aa)
initn: 2496 init1: 2496 opt: 2496 Z-score: 2892.4 bits: 543.7 E(85289): 2.3e-154
Smith-Waterman score: 2496; 100.0% identity (100.0% similar) in 355 aa overlap (1-355:1-355)
10 20 30 40 50 60
pF1KE4 MARRPRNSRAWHFVLSAARRDADARAVALAGSTNWGYDSDGQHSDSDSDPEYSTLPPSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 MARRPRNSRAWHFVLSAARRDADARAVALAGSTNWGYDSDGQHSDSDSDPEYSTLPPSIP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SAVPVTGESFCDCAGQSEASFCSSLHSAHRGRDCRCGEEDEYFDWVWDDLNKSSATLLSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 SAVPVTGESFCDCAGQSEASFCSSLHSAHRGRDCRCGEEDEYFDWVWDDLNKSSATLLSC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 DNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 TFCSLLGRDEDSWGLSYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 TFCSLLGRDEDSWGLSYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GVAATKLQNKRFYPMVCSTAARSSMKVTRSCASATSLQYLCCHRLRQLRPDSGDTLEGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 GVAATKLQNKRFYPMVCSTAARSSMKVTRSCASATSLQYLCCHRLRQLRPDSGDTLEGLP
250 260 270 280 290 300
310 320 330 340 350
pF1KE4 LPPGLKQVLHNKLGWVLSMSCSRRKAPVSDPQAATSAHPSSREPRPCQRKRCRRT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 LPPGLKQVLHNKLGWVLSMSCSRRKAPVSDPQAATSAHPSSREPRPCQRKRCRRT
310 320 330 340 350
>>NP_001311010 (OMIM: 611659) SPRY domain-containing SOC (355 aa)
initn: 2496 init1: 2496 opt: 2496 Z-score: 2892.4 bits: 543.7 E(85289): 2.3e-154
Smith-Waterman score: 2496; 100.0% identity (100.0% similar) in 355 aa overlap (1-355:1-355)
10 20 30 40 50 60
pF1KE4 MARRPRNSRAWHFVLSAARRDADARAVALAGSTNWGYDSDGQHSDSDSDPEYSTLPPSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MARRPRNSRAWHFVLSAARRDADARAVALAGSTNWGYDSDGQHSDSDSDPEYSTLPPSIP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SAVPVTGESFCDCAGQSEASFCSSLHSAHRGRDCRCGEEDEYFDWVWDDLNKSSATLLSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAVPVTGESFCDCAGQSEASFCSSLHSAHRGRDCRCGEEDEYFDWVWDDLNKSSATLLSC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 TFCSLLGRDEDSWGLSYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFCSLLGRDEDSWGLSYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 GVAATKLQNKRFYPMVCSTAARSSMKVTRSCASATSLQYLCCHRLRQLRPDSGDTLEGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVAATKLQNKRFYPMVCSTAARSSMKVTRSCASATSLQYLCCHRLRQLRPDSGDTLEGLP
250 260 270 280 290 300
310 320 330 340 350
pF1KE4 LPPGLKQVLHNKLGWVLSMSCSRRKAPVSDPQAATSAHPSSREPRPCQRKRCRRT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPGLKQVLHNKLGWVLSMSCSRRKAPVSDPQAATSAHPSSREPRPCQRKRCRRT
310 320 330 340 350
>>XP_005255730 (OMIM: 611659) PREDICTED: SPRY domain-con (410 aa)
initn: 2213 init1: 2213 opt: 2223 Z-score: 2575.3 bits: 485.2 E(85289): 1e-136
Smith-Waterman score: 2223; 90.7% identity (94.4% similar) in 355 aa overlap (3-355:58-410)
10 20 30
pF1KE4 MARRPRNSRAWHFVLSAARRDADARAVALAGS
: ::.. . :.. . . . :: : .
XP_005 ALAGSTNWGYDSDGQVGSSGRGGRGWPKVWRCPRQA-GRHYLNTESVGEKDASE-ARGPV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE4 TNWG--YDSDGQHSDSDSDPEYSTLPPSIPSAVPVTGESFCDCAGQSEASFCSSLHSAHR
.:. :. .::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTWACLLDAPHSHSDSDSDPEYSTLPPSIPSAVPVTGESFCDCAGQSEASFCSSLHSAHR
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE4 GRDCRCGEEDEYFDWVWDDLNKSSATLLSCDNRKVSFHMEYSCGTAAIRGTKELGEGQHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRDCRCGEEDEYFDWVWDDLNKSSATLLSCDNRKVSFHMEYSCGTAAIRGTKELGEGQHF
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE4 WEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWGLSYTGLLHHKGDKTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWGLSYTGLLHHKGDKTSF
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE4 SSRFGQGSIIGVHLDTWHGTLTFFKNRKCIGVAATKLQNKRFYPMVCSTAARSSMKVTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSRFGQGSIIGVHLDTWHGTLTFFKNRKCIGVAATKLQNKRFYPMVCSTAARSSMKVTRS
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE4 CASATSLQYLCCHRLRQLRPDSGDTLEGLPLPPGLKQVLHNKLGWVLSMSCSRRKAPVSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CASATSLQYLCCHRLRQLRPDSGDTLEGLPLPPGLKQVLHNKLGWVLSMSCSRRKAPVSD
330 340 350 360 370 380
340 350
pF1KE4 PQAATSAHPSSREPRPCQRKRCRRT
:::::::::::::::::::::::::
XP_005 PQAATSAHPSSREPRPCQRKRCRRT
390 400 410
>--
initn: 333 init1: 290 opt: 290 Z-score: 336.6 bits: 71.0 E(85289): 5.2e-12
Smith-Waterman score: 290; 93.5% identity (97.8% similar) in 46 aa overlap (1-46:1-46)
10 20 30 40 50 60
pF1KE4 MARRPRNSRAWHFVLSAARRDADARAVALAGSTNWGYDSDGQHSDSDSDPEYSTLPPSIP
:::::::::::::::::::::::::::::::::::::::::: ..:
XP_005 MARRPRNSRAWHFVLSAARRDADARAVALAGSTNWGYDSDGQVGSSGRGGRGWPKVWRCP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 SAVPVTGESFCDCAGQSEASFCSSLHSAHRGRDCRCGEEDEYFDWVWDDLNKSSATLLSC
XP_005 RQAGRHYLNTESVGEKDASEARGPVQTWACLLDAPHSHSDSDSDPEYSTLPPSIPSAVPV
70 80 90 100 110 120
>>NP_079382 (OMIM: 611657) SPRY domain-containing SOCS b (273 aa)
initn: 223 init1: 88 opt: 206 Z-score: 241.9 bits: 52.9 E(85289): 9.8e-07
Smith-Waterman score: 227; 28.0% identity (56.0% similar) in 218 aa overlap (107-309:56-270)
80 90 100 110 120 130
pF1KE4 SEASFCSSLHSAHRGRDCRCGEEDEYFDWVWDDLNKSSATLLSCDNRKVSFHMEYSCGTA
:.. ..: .... :.. . . . .:
NP_079 LQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNNDRSLNVFVKEDDKLIFHRHPVAQSTD
30 40 50 60 70 80
140 150 160 170 180 190
pF1KE4 AIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWGLS
:::: .: : :.: . :: .::..:.:. : . .: .:.: ...::: .
NP_079 AIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATADAPLHSVGYT--TLVGNNHESWGWD
90 100 110 120 130 140
200 210 220 230 240
pF1KE4 Y-TGLLHHKG----DKT--SF---SSRFGQGSIIGVHLDTWHGTLTFFKNRKCIGVAATK
. :.: : .:: .: . : . . : :: :::.:. . . .:::
NP_079 LGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVALDMDDGTLSFIVDGQYMGVAFRG
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE4 LQNKRFYPMVCSTAARSSMKVTRSCA---SATSLQYLCCH--RLRQLRPDSGDTLEGLPL
:..:..::.: .. .. ... . :. :: . :: : :. .. :::
NP_079 LKGKKLYPVVSAVWGHCEIRMRYLNGLDPEPLPLMDLCRRSVRLALGRERLGE-IHTLPL
210 220 230 240 250 260
310 320 330 340 350
pF1KE4 PPGLKQVLHNKLGWVLSMSCSRRKAPVSDPQAATSAHPSSREPRPCQRKRCRRT
: .:: :
NP_079 PASLKAYLLYQ
270
>>NP_543138 (OMIM: 611660) SPRY domain-containing SOCS b (273 aa)
initn: 216 init1: 85 opt: 190 Z-score: 223.4 bits: 49.5 E(85289): 1.1e-05
Smith-Waterman score: 224; 26.9% identity (58.4% similar) in 219 aa overlap (107-310:56-271)
80 90 100 110 120 130
pF1KE4 SEASFCSSLHSAHRGRDCRCGEEDEYFDWVWDDLNKSSATLLSCDNRKVSFHME-YSCGT
:. ..: .... :.: ..:: . . .:
NP_543 LRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDR-LTFHRHPVAQST
30 40 50 60 70 80
140 150 160 170 180 190
pF1KE4 AAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWGL
.::: ..: : :.:. . :: .::..:. . : . .: .:.: : .:::
NP_543 DGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATARAPLHSVGYT--ALVGSDAESWGW
90 100 110 120 130 140
200 210 220 230 240
pF1KE4 SY-TGLLHHKGDK---TSFSSRFGQGSIIG------VHLDTWHGTLTFFKNRKCIGVAAT
. . :.: : . ... . .: .. : :: .:::.:. . . .:::
NP_543 DLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIVDGQYLGVAFR
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE4 KLQNKRFYPMVCSTAARS--SMKVTRSC-ASATSLQYLCCHRLRQ-LRPDSGDTLEGLPL
:..:..::.: .. .. .:. . :. :: . .:. : . . . .:::
NP_543 GLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDLCRRSIRSALGRQRLQDISSLPL
210 220 230 240 250 260
310 320 330 340 350
pF1KE4 PPGLKQVLHNKLGWVLSMSCSRRKAPVSDPQAATSAHPSSREPRPCQRKRCRRT
: .::. :.
NP_543 PQSLKNYLQYQ
270
>>NP_001099043 (OMIM: 609112) F-box/SPRY domain-containi (286 aa)
initn: 134 init1: 59 opt: 170 Z-score: 199.9 bits: 45.2 E(85289): 0.00021
Smith-Waterman score: 170; 31.8% identity (59.8% similar) in 132 aa overlap (144-268:150-276)
120 130 140 150 160 170
pF1KE4 SATLLSCDNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDV
..::.: ::. .:. :: ..::.:. .
NP_001 SRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPL-GTVAVIGIATKRA
120 130 140 150 160 170
180 190 200 210 220
pF1KE4 DLDKYRHTFCSLLGRDEDSWG--LSYTGLLHHKGDKTSF-----SSRFGQGSIIGVHLDT
.. . . .::: :..::: : ..:::. . :: . .. : : : ::
NP_001 PMQC--QGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDM
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE4 WHGTLTFFKNRKCIGVAATKLQNKRFYPMVCSTAARSSMKVTRSCASATSLQYLCCHRLR
::.: .. . .::: : . .:: : .:. .. .::
NP_001 EDKTLAFERGYEFLGVAFRGLPKVCLYPAV--SAVYGNTEVTLVYLGKPLDG
240 250 260 270 280
290 300 310 320 330 340
pF1KE4 QLRPDSGDTLEGLPLPPGLKQVLHNKLGWVLSMSCSRRKAPVSDPQAATSAHPSSREPRP
>>XP_016862998 (OMIM: 611660) PREDICTED: SPRY domain-con (233 aa)
initn: 185 init1: 85 opt: 167 Z-score: 197.8 bits: 44.5 E(85289): 0.00028
Smith-Waterman score: 201; 28.6% identity (60.2% similar) in 161 aa overlap (107-256:56-213)
80 90 100 110 120 130
pF1KE4 SEASFCSSLHSAHRGRDCRCGEEDEYFDWVWDDLNKSSATLLSCDNRKVSFHME-YSCGT
:. ..: .... :.: ..:: . . .:
XP_016 LRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPEDRSLNVFVKDDDR-LTFHRHPVAQST
30 40 50 60 70 80
140 150 160 170 180 190
pF1KE4 AAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWGL
.::: ..: : :.:. . :: .::..:. . : . .: .:.: : .:::
XP_016 DGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATARAPLHSVGYT--ALVGSDAESWGW
90 100 110 120 130 140
200 210 220 230 240
pF1KE4 SY-TGLLHHKGDK---TSFSSRFGQGSIIG------VHLDTWHGTLTFFKNRKCIGVAAT
. . :.: : . ... . .: .. : :: .:::.:. . . .:::
XP_016 DLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSFIVDGQYLGVAFR
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE4 KLQNKRFYPMVCSTAARSSMKVTRSCASATSLQYLCCHRLRQLRPDSGDTLEGLPLPPGL
:..:..::.:
XP_016 GLKGKKLYPVVSAVWGHCEVTMRYINGLDQN
210 220 230
>>XP_016856812 (OMIM: 610584) PREDICTED: tripartite moti (854 aa)
initn: 93 init1: 56 opt: 165 Z-score: 187.2 bits: 44.4 E(85289): 0.0011
Smith-Waterman score: 165; 22.8% identity (50.8% similar) in 250 aa overlap (104-342:606-840)
80 90 100 110 120 130
pF1KE4 AGQSEASFCSSLHSAHRGRDCRCGEEDEYFDWVWDDLNKSSA---TLLSCDNRKVSFHME
: .: .. .:. .:: ::. ..
XP_016 HFNSTYNARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSGHRDIILSNDNQTATCS--
580 590 600 610 620 630
140 150 160 170 180 190
pF1KE4 YSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIGTSDVDLDKYRHTFCSLLGRDE
: .. :: ...: :.::... : :.. ..: : .::.:.
XP_016 -SYDDRVVLGTAAFSKGVHYWELHVDRYDNHPDPAFGVARASVVKDM-------MLGKDD
640 650 660 670 680
200 210 220 230 240
pF1KE4 DSWGL----SYTGLLHHKGDKTSFSSRFGQGSIIGVHLDTWHGTLTFFKNRKCIGVAATK
.:.. . . ..: .. . . .:. .:: :: . ::::: : . : .: .
XP_016 KAWAMYVDNNRSWFMHCNSHTNRTEGGVCKGATVGVLLDLNKHTLTFFINGQQQGPTAFS
690 700 710 720 730 740
250 260 270 280 290 300
pF1KE4 LQNKRFYPMVCSTAARSSMKVTRSCASATSLQYLCCHRLRQLRPDSGDTLEGLPLPPGLK
. :.: . . :. . : . . : ::: : : . ... : :.
XP_016 HVDGVFMPAL--SLNRNVQVHTSPGPDLVWLLPTVCHRSLQC-PWAEWAIKKLTTEPSQT
750 760 770 780 790 800
310 320 330 340 350
pF1KE4 QVLHNK---LGWVLS-MSCSRRKAPVSDPQAATSAHPSSREPRPCQRKRCRRT
.... ..: : ..:: .: :..:.:. . :
XP_016 ELINWPALDISWRRSVLTCSL-GTP-RGPKVAASGDADLRTELSPWGVLVAQEA
810 820 830 840 850
>>NP_116030 (OMIM: 611658) SPRY domain-containing SOCS b (263 aa)
initn: 201 init1: 77 opt: 156 Z-score: 184.2 bits: 42.2 E(85289): 0.0016
Smith-Waterman score: 192; 29.1% identity (51.9% similar) in 189 aa overlap (135-309:75-260)
110 120 130 140 150 160
pF1KE4 WVWDDLNKSSATLLSCDNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDM
: . :: . ..: : :::. ::
NP_116 RHGWNPKDCSENIEVKEGGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHA
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 MVGIGTSDVDLDKYRHTFCSLLGRDEDSWGLSY-TGLLHH--KGDKTSFSSRFGQGSIIG
.::..:. . : . : . .::: . .::: . : :.: :: . :: .
NP_116 VVGVATALAPL-QTDH-YAALLGSNSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLE
110 120 130 140 150 160
230 240 250 260 270
pF1KE4 VH------LDTWHGTLTFFKNRKCIGVAATKLQNKRFYPMVCSTAARSSMKVTRSCASAT
: :: .::: . . .: : :... .:: : .. .. .... : .
NP_116 VPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRI-RYLGERR
170 180 190 200 210 220
280 290 300 310 320 330
pF1KE4 SLQYLCCHRLRQ-LRPDSGDTLEG----LPLPPGLKQVLHNKLGWVLSMSCSRRKAPVSD
. . : : .: . ::: : :::::..:. :
NP_116 AEPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYLLYQ
230 240 250 260
340 350
pF1KE4 PQAATSAHPSSREPRPCQRKRCRRT
>>NP_001139788 (OMIM: 611658) SPRY domain-containing SOC (263 aa)
initn: 201 init1: 77 opt: 156 Z-score: 184.2 bits: 42.2 E(85289): 0.0016
Smith-Waterman score: 192; 29.1% identity (51.9% similar) in 189 aa overlap (135-309:75-260)
110 120 130 140 150 160
pF1KE4 WVWDDLNKSSATLLSCDNRKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDM
: . :: . ..: : :::. ::
NP_001 RHGWNPKDCSENIEVKEGGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHA
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 MVGIGTSDVDLDKYRHTFCSLLGRDEDSWGLSY-TGLLHH--KGDKTSFSSRFGQGSIIG
.::..:. . : . : . .::: . .::: . : :.: :: . :: .
NP_001 VVGVATALAPL-QTDH-YAALLGSNSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLE
110 120 130 140 150 160
230 240 250 260 270
pF1KE4 VH------LDTWHGTLTFFKNRKCIGVAATKLQNKRFYPMVCSTAARSSMKVTRSCASAT
: :: .::: . . .: : :... .:: : .. .. .... : .
NP_001 VPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRI-RYLGERR
170 180 190 200 210 220
280 290 300 310 320 330
pF1KE4 SLQYLCCHRLRQ-LRPDSGDTLEG----LPLPPGLKQVLHNKLGWVLSMSCSRRKAPVSD
. . : : .: . ::: : :::::..:. :
NP_001 AEPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYLLYQ
230 240 250 260
340 350
pF1KE4 PQAATSAHPSSREPRPCQRKRCRRT
355 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:32:16 2016 done: Sun Nov 6 03:32:17 2016
Total Scan time: 8.800 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]