Result of FASTA (ccds) for
pFN21AE4065
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4065, 346 aa
1>>>pF1KE4065 346 - 346 aa - 346 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4661+/-0.000889; mu= 7.9809+/- 0.054
mean_var=173.5470+/-35.054, 0's: 0 Z-trim(112.7): 69 B-trim: 51 in 1/51
Lambda= 0.097357
statistics sampled from 13319 (13388) to 13319 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.768), E-opt: 0.2 (0.411), width: 16
Scan time: 3.010
The best scores are: opt bits E(32554)
CCDS32823.1 RNF165 gene_id:494470|Hs108|chr18 ( 346) 2438 354.2 9.5e-98
CCDS58621.1 RNF165 gene_id:494470|Hs108|chr18 ( 154) 1073 162.1 2.7e-40
CCDS10169.1 RNF111 gene_id:54778|Hs108|chr15 ( 986) 865 133.6 6.5e-31
CCDS58366.1 RNF111 gene_id:54778|Hs108|chr15 ( 994) 850 131.5 2.8e-30
CCDS58365.1 RNF111 gene_id:54778|Hs108|chr15 ( 995) 810 125.9 1.4e-28
CCDS81888.1 RNF111 gene_id:54778|Hs108|chr15 (1003) 777 121.3 3.5e-27
>>CCDS32823.1 RNF165 gene_id:494470|Hs108|chr18 (346 aa)
initn: 2438 init1: 2438 opt: 2438 Z-score: 1868.4 bits: 354.2 E(32554): 9.5e-98
Smith-Waterman score: 2438; 100.0% identity (100.0% similar) in 346 aa overlap (1-346:1-346)
10 20 30 40 50 60
pF1KE4 MVLVHVGYLVLPVFGSVRNRGAPFQRSQHPHATSCRHFHLGPPQPQQLAPDFPLAHPVQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 MVLVHVGYLVLPVFGSVRNRGAPFQRSQHPHATSCRHFHLGPPQPQQLAPDFPLAHPVQS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 QPGLSAHMAPAHQHSGALHQSLTPLPTLQFQDVTGPSFLPQALHQQYLLQQQLLEAQHRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 QPGLSAHMAPAHQHSGALHQSLTPLPTLQFQDVTGPSFLPQALHQQYLLQQQLLEAQHRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LVSHPRRSQERVSVHPHRLHPSFDFGQLQTPQPRYLAEGTDWDLSVDAGLSPAQFQVRPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 LVSHPRRSQERVSVHPHRLHPSFDFGQLQTPQPRYLAEGTDWDLSVDAGLSPAQFQVRPI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 PQHYQHYLATPRMHHFPRNSSSTQMVVHEIRNYPYPQLHFLALQGLNPSRHTSAVRESYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 PQHYQHYLATPRMHHFPRNSSSTQMVVHEIRNYPYPQLHFLALQGLNPSRHTSAVRESYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 ELLQLEDRLGNVTRGAVQNTIERFTFPHKYKKRRPQDGKGKKDEGEESDTDEKCTICLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 ELLQLEDRLGNVTRGAVQNTIERFTFPHKYKKRRPQDGKGKKDEGEESDTDEKCTICLSM
250 260 270 280 290 300
310 320 330 340
pF1KE4 LEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQLGADS
::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 LEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQLGADS
310 320 330 340
>>CCDS58621.1 RNF165 gene_id:494470|Hs108|chr18 (154 aa)
initn: 1073 init1: 1073 opt: 1073 Z-score: 836.8 bits: 162.1 E(32554): 2.7e-40
Smith-Waterman score: 1073; 100.0% identity (100.0% similar) in 154 aa overlap (193-346:1-154)
170 180 190 200 210 220
pF1KE4 DLSVDAGLSPAQFQVRPIPQHYQHYLATPRMHHFPRNSSSTQMVVHEIRNYPYPQLHFLA
::::::::::::::::::::::::::::::
CCDS58 MHHFPRNSSSTQMVVHEIRNYPYPQLHFLA
10 20 30
230 240 250 260 270 280
pF1KE4 LQGLNPSRHTSAVRESYEELLQLEDRLGNVTRGAVQNTIERFTFPHKYKKRRPQDGKGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LQGLNPSRHTSAVRESYEELLQLEDRLGNVTRGAVQNTIERFTFPHKYKKRRPQDGKGKK
40 50 60 70 80 90
290 300 310 320 330 340
pF1KE4 DEGEESDTDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 DEGEESDTDEKCTICLSMLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQL
100 110 120 130 140 150
pF1KE4 GADS
::::
CCDS58 GADS
>>CCDS10169.1 RNF111 gene_id:54778|Hs108|chr15 (986 aa)
initn: 690 init1: 389 opt: 865 Z-score: 668.4 bits: 133.6 E(32554): 6.5e-31
Smith-Waterman score: 923; 42.3% identity (66.2% similar) in 364 aa overlap (12-346:637-986)
10 20 30
pF1KE4 MVLVHVGYLVLPVFGSVRNRGAP----FQRSQHPHATSCRH
: ..: :. : . : : .:..: :
CCDS10 AAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQASACPH
610 620 630 640 650 660
40 50 60 70 80
pF1KE4 FHLGPPQPQQLAP---DFPLAHPVQS-QPGLSAHMA--------PAHQHSGA--LHQSLT
: .:: :: : :. . :::.. . .:.: . :.: : : . : :
CCDS10 SHGNPP-PQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPIPQHLP
670 680 690 700 710 720
90 100 110 120 130 140
pF1KE4 PL--PTLQFQDVTGPSFLPQALHQQYLLQQQLLEAQHRRLVSHPRRSQERVSVHPHRLHP
: : . .:.: : :: . ..:. .:.:.::...:: :..:: ::::.::
CCDS10 PTHQPISHHIPATAPP--AQRLHPHEVMQR--MEVQRRRMMQHPTRAHERPPPHPHRMHP
730 740 750 760 770 780
150 160 170 180 190
pF1KE4 SFDFGQ-LQTPQ-----PRYLAEGTDWDLSVDAGLSPAQFQVRPIPQHYQHYLATPRMHH
.. :. ...:: :: : . :.:...::.. : . . : :: : ::.::
CCDS10 NYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHH
790 800 810 820 830 840
200 210 220 230 240 250
pF1KE4 FPRNSSSTQMVVHEIRNYPYPQLHFLALQGLNPSRHTSAVRESYEELLQLEDRLGNVTRG
. . .. ..: .. .::. ..... .::. . . : ..:::..::.:::::.::
CCDS10 L--QLGALPLMVPDMAGYPH--IRYIS-SGLDGTSFRGPFRGNFEELIHLEERLGNVNRG
850 860 870 880 890
260 270 280 290 300 310
pF1KE4 AVQNTIERFTFPHKYKKRR---PQDGKGKKDEGEESDTDEKCTICLSMLEDGEDVRRLPC
: :.:::: :.:::::::. ::: .:: : ::.::::::::.::.:::::::::
CCDS10 ASQGTIERCTYPHKYKKRKLHCKQDG----EEGTEEDTEEKCTICLSILEEGEDVRRLPC
900 910 920 930 940 950
320 330 340
pF1KE4 MHLFHQLCVDQWLAMSKKCPICRVDIETQLGADS
::::::.:::::: .:::::::::::.:: ..:
CCDS10 MHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES
960 970 980
>>CCDS58366.1 RNF111 gene_id:54778|Hs108|chr15 (994 aa)
initn: 798 init1: 377 opt: 850 Z-score: 657.0 bits: 131.5 E(32554): 2.8e-30
Smith-Waterman score: 903; 41.3% identity (64.9% similar) in 368 aa overlap (12-346:637-994)
10 20 30
pF1KE4 MVLVHVGYLVLPVFGSVRNRGAP----FQRSQHPHATSCRH
: ..: :. : . : : .:..: :
CCDS58 AAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQASACPH
610 620 630 640 650 660
40 50 60 70 80
pF1KE4 FHLGPPQPQQLAP---DFPLAHPVQS-QPGLSAHMA--------PAHQHSGA--LHQSLT
: .:: :: : :. . :::.. . .:.: . :.: : : . : :
CCDS58 SHGNPP-PQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPIPQHLP
670 680 690 700 710 720
90 100 110 120 130 140
pF1KE4 PL--PTLQFQDVTGPSFLPQALHQQYLLQQQLLEAQHRRLVSHPRRSQERVSVHPHRLHP
: : . .:.: : :: . ..:. .:.:.::...:: :..:: ::::.::
CCDS58 PTHQPISHHIPATAPP--AQRLHPHEVMQR--MEVQRRRMMQHPTRAHERPPPHPHRMHP
730 740 750 760 770 780
150 160 170 180 190
pF1KE4 SFDFGQ-LQTPQ-----PRYLAEGTDWDLSVDAGLSPAQFQVRPIPQHYQHYLATPRMHH
.. :. ...:: :: : . :.:...::.. : . . : :: : ::.::
CCDS58 NYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHH
790 800 810 820 830 840
200 210 220 230 240 250
pF1KE4 FPRNSSSTQMVVHEIRNYPYPQLHFLALQGLNPSRHTSAVRESYEELLQLEDRLGNVTRG
. . .. ..: .. .::. ..... .::. . . : ..:::..::.:::::.::
CCDS58 L--QLGALPLMVPDMAGYPH--IRYIS-SGLDGTSFRGPFRGNFEELIHLEERLGNVNRG
850 860 870 880 890
260 270 280 290 300
pF1KE4 AVQNTIERFTFPHKYKK-------RRPQDGKGKKDEGEESDTDEKCTICLSMLEDGEDVR
: :.:::: :.:::::: .: : .:: : ::.::::::::.::.:::::
CCDS58 ASQGTIERCTYPHKYKKVTTDWFSQRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVR
900 910 920 930 940 950
310 320 330 340
pF1KE4 RLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQLGADS
::::::::::.:::::: .:::::::::::.:: ..:
CCDS58 RLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES
960 970 980 990
>>CCDS58365.1 RNF111 gene_id:54778|Hs108|chr15 (995 aa)
initn: 682 init1: 389 opt: 810 Z-score: 626.6 bits: 125.9 E(32554): 1.4e-28
Smith-Waterman score: 903; 41.6% identity (64.9% similar) in 373 aa overlap (12-346:637-995)
10 20 30
pF1KE4 MVLVHVGYLVLPVFGSVRNRGAP----FQRSQHPHATSCRH
: ..: :. : . : : .:..: :
CCDS58 AAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQASACPH
610 620 630 640 650 660
40 50 60 70 80
pF1KE4 FHLGPPQPQQLAP---DFPLAHPVQS-QPGLSAHMA--------PAHQHSGA--LHQSLT
: .:: :: : :. . :::.. . .:.: . :.: : : . : :
CCDS58 SHGNPP-PQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPIPQHLP
670 680 690 700 710 720
90 100 110 120 130
pF1KE4 PL--PTLQFQDVTGPSFLPQALHQQYLLQQQLLEAQHRRLVSHP---------RRSQERV
: : . .:.: : :: . ..:. .:.:.::...:: ::..::
CCDS58 PTHQPISHHIPATAPP--AQRLHPHEVMQR--MEVQRRRMMQHPTGLFVFCVSRRAHERP
730 740 750 760 770 780
140 150 160 170 180
pF1KE4 SVHPHRLHPSFDFGQ-LQTPQ-----PRYLAEGTDWDLSVDAGLSPAQFQVRPIPQHYQH
::::.::.. :. ...:: :: : . :.:...::.. : . . : :
CCDS58 PPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAH
790 800 810 820 830 840
190 200 210 220 230 240
pF1KE4 YLATPRMHHFPRNSSSTQMVVHEIRNYPYPQLHFLALQGLNPSRHTSAVRESYEELLQLE
: : ::.::. . .. ..: .. .::. ..... .::. . . : ..:::..::
CCDS58 YHAPPRLHHL--QLGALPLMVPDMAGYPH--IRYIS-SGLDGTSFRGPFRGNFEELIHLE
850 860 870 880 890
250 260 270 280 290 300
pF1KE4 DRLGNVTRGAVQNTIERFTFPHKYKKRR---PQDGKGKKDEGEESDTDEKCTICLSMLED
.:::::.::: :.:::: :.:::::::. ::: .:: : ::.::::::::.::.
CCDS58 ERLGNVNRGASQGTIERCTYPHKYKKRKLHCKQDG----EEGTEEDTEEKCTICLSILEE
900 910 920 930 940 950
310 320 330 340
pF1KE4 GEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQLGADS
:::::::::::::::.:::::: .:::::::::::.:: ..:
CCDS58 GEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES
960 970 980 990
>>CCDS81888.1 RNF111 gene_id:54778|Hs108|chr15 (1003 aa)
initn: 740 init1: 377 opt: 777 Z-score: 601.5 bits: 121.3 E(32554): 3.5e-27
Smith-Waterman score: 883; 40.6% identity (63.7% similar) in 377 aa overlap (12-346:637-1003)
10 20 30
pF1KE4 MVLVHVGYLVLPVFGSVRNRGAP----FQRSQHPHATSCRH
: ..: :. : . : : .:..: :
CCDS81 AAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQASACPH
610 620 630 640 650 660
40 50 60 70 80
pF1KE4 FHLGPPQPQQLAP---DFPLAHPVQS-QPGLSAHMA--------PAHQHSGA--LHQSLT
: .:: :: : :. . :::.. . .:.: . :.: : : . : :
CCDS81 SHGNPP-PQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPIPQHLP
670 680 690 700 710 720
90 100 110 120 130
pF1KE4 PL--PTLQFQDVTGPSFLPQALHQQYLLQQQLLEAQHRRLVSHP---------RRSQERV
: : . .:.: : :: . ..:. .:.:.::...:: ::..::
CCDS81 PTHQPISHHIPATAPP--AQRLHPHEVMQR--MEVQRRRMMQHPTGLFVFCVSRRAHERP
730 740 750 760 770 780
140 150 160 170 180
pF1KE4 SVHPHRLHPSFDFGQ-LQTPQ-----PRYLAEGTDWDLSVDAGLSPAQFQVRPIPQHYQH
::::.::.. :. ...:: :: : . :.:...::.. : . . : :
CCDS81 PPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAH
790 800 810 820 830 840
190 200 210 220 230 240
pF1KE4 YLATPRMHHFPRNSSSTQMVVHEIRNYPYPQLHFLALQGLNPSRHTSAVRESYEELLQLE
: : ::.::. . .. ..: .. .::. ..... .::. . . : ..:::..::
CCDS81 YHAPPRLHHL--QLGALPLMVPDMAGYPH--IRYIS-SGLDGTSFRGPFRGNFEELIHLE
850 860 870 880 890
250 260 270 280 290
pF1KE4 DRLGNVTRGAVQNTIERFTFPHKYKK-------RRPQDGKGKKDEGEESDTDEKCTICLS
.:::::.::: :.:::: :.:::::: .: : .:: : ::.::::::::
CCDS81 ERLGNVNRGASQGTIERCTYPHKYKKVTTDWFSQRKLHCKQDGEEGTEEDTEEKCTICLS
900 910 920 930 940 950
300 310 320 330 340
pF1KE4 MLEDGEDVRRLPCMHLFHQLCVDQWLAMSKKCPICRVDIETQLGADS
.::.:::::::::::::::.:::::: .:::::::::::.:: ..:
CCDS81 ILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES
960 970 980 990 1000
346 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:00:41 2016 done: Sun Nov 6 04:00:41 2016
Total Scan time: 3.010 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]