Result of FASTA (ccds) for
pFN21AE4053
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4053, 300 aa
1>>>pF1KE4053 300 - 300 aa - 300 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8556+/-0.000676; mu= 18.4143+/- 0.041
mean_var=71.8923+/-14.443, 0's: 0 Z-trim(110.5): 41 B-trim: 2 in 1/51
Lambda= 0.151263
statistics sampled from 11635 (11676) to 11635 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.359), width: 16
Scan time: 2.820
The best scores are: opt bits E(32554)
CCDS31273.1 FBXL15 gene_id:79176|Hs108|chr10 ( 300) 2026 450.8 5.7e-127
CCDS64129.1 FBXL7 gene_id:23194|Hs108|chr5 ( 444) 287 71.5 1.3e-12
CCDS54833.1 FBXL7 gene_id:23194|Hs108|chr5 ( 491) 287 71.5 1.4e-12
CCDS54886.1 FBXL17 gene_id:64839|Hs108|chr5 ( 701) 272 68.4 1.8e-11
CCDS8509.1 FBXL14 gene_id:144699|Hs108|chr12 ( 418) 269 67.5 1.9e-11
CCDS54116.1 FBXL20 gene_id:84961|Hs108|chr17 ( 404) 264 66.4 4e-11
CCDS32640.1 FBXL20 gene_id:84961|Hs108|chr17 ( 436) 264 66.5 4.2e-11
CCDS54560.1 FBXL2 gene_id:25827|Hs108|chr3 ( 355) 259 65.3 7.7e-11
>>CCDS31273.1 FBXL15 gene_id:79176|Hs108|chr10 (300 aa)
initn: 2026 init1: 2026 opt: 2026 Z-score: 2393.1 bits: 450.8 E(32554): 5.7e-127
Smith-Waterman score: 2026; 100.0% identity (100.0% similar) in 300 aa overlap (1-300:1-300)
10 20 30 40 50 60
pF1KE4 MEPPMEPSGGEQEPGAVRFLDLPWEDVLLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MEPPMEPSGGEQEPGAVRFLDLPWEDVLLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 GLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 DEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 DEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE4 AEYCPVLRSLRVRHCHHVAESSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 AEYCPVLRSLRVRHCHHVAESSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV
250 260 270 280 290 300
>>CCDS64129.1 FBXL7 gene_id:23194|Hs108|chr5 (444 aa)
initn: 396 init1: 163 opt: 287 Z-score: 339.9 bits: 71.5 E(32554): 1.3e-12
Smith-Waterman score: 287; 30.6% identity (65.6% similar) in 160 aa overlap (116-268:141-300)
90 100 110 120 130 140
pF1KE4 AEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRL
:..:...:: .:. :.: ..:. ::.:.::
CCDS64 RLTGETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRL
120 130 140 150 160 170
150 160 170 180 190
pF1KE4 SLAHCDWVDGLALRGLADRCPALEELDLTACRQ-----LKDEAIVYLAQRRGA--GLRSL
.. : ... :. ... :: ::.::...: . : :: . :. .: ..: :
CCDS64 EVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYL
180 190 200 210 220 230
200 210 220 230 240 250
pF1KE4 SLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHV
... . : ... .: .: .: :: : :.:. ..:.: :. :: .. : : :. :
CCDS64 DMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFV
240 250 260 270 280 290
260 270 280 290 300
pF1KE4 AESSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV
.. .: .. :
CCDS64 SDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYL
300 310 320 330 340 350
>>CCDS54833.1 FBXL7 gene_id:23194|Hs108|chr5 (491 aa)
initn: 396 init1: 163 opt: 287 Z-score: 339.3 bits: 71.5 E(32554): 1.4e-12
Smith-Waterman score: 287; 30.6% identity (65.6% similar) in 160 aa overlap (116-268:188-347)
90 100 110 120 130 140
pF1KE4 AEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRL
:..:...:: .:. :.: ..:. ::.:.::
CCDS54 RLTGETINVDRALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRL
160 170 180 190 200 210
150 160 170 180 190
pF1KE4 SLAHCDWVDGLALRGLADRCPALEELDLTACRQ-----LKDEAIVYLAQRRGA--GLRSL
.. : ... :. ... :: ::.::...: . : :: . :. .: ..: :
CCDS54 EVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYL
220 230 240 250 260 270
200 210 220 230 240 250
pF1KE4 SLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHV
... . : ... .: .: .: :: : :.:. ..:.: :. :: .. : : :. :
CCDS54 DMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFV
280 290 300 310 320 330
260 270 280 290 300
pF1KE4 AESSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV
.. .: .. :
CCDS54 SDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYL
340 350 360 370 380 390
>>CCDS54886.1 FBXL17 gene_id:64839|Hs108|chr5 (701 aa)
initn: 356 init1: 147 opt: 272 Z-score: 319.5 bits: 68.4 E(32554): 1.8e-11
Smith-Waterman score: 272; 25.0% identity (57.7% similar) in 272 aa overlap (2-269:302-564)
10 20
pF1KE4 MEPPMEPSGGEQEPGAVR--FLDLPWEDVLL
: : .: ..:: . .:: ..::
CCDS54 TEAGGDAVRAGGTAPLSAQQQHECGDADCRESPENPCDCHREPPPETPDINQLP-PSILL
280 290 300 310 320 330
30 40 50 60 70 80
pF1KE4 PHVLNRVPL-RQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAEG
.... . : .. : . : . .:.: : . ...: .. :. : .. ...
CCDS54 -KIFSNLSLDERCLSASLVCKYWRDLC-LDFQFWKQLDLSSR-QQVTDELLEKIASRSQN
340 350 360 370 380
90 100 110 120 130 140
pF1KE4 LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLA
. :. .. :. .::. . . . : : . : ::: .. :.: :: ::.. ..
CCDS54 IIEINISDCRS-MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVG
390 400 410 420 430 440
150 160 170 180 190 200
pF1KE4 HCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGA-GLRSLSLAVNANVG
. : . .:. :...: :... . : ...::... .: .: :. . . : :
CCDS54 NQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIA--KGCLKLQRIYMQENKLVT
450 460 470 480 490 500
210 220 230 240 250 260
pF1KE4 DAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRLR
: .:. .:..::::... . :: : : :: :.. : :: .:: .. . .. ..
CCDS54 DQSVKAFAEHCPELQYVGFMGC-SVTSKGVIHLTKLRN-LSSLDLRHITELDNETVMEIV
510 520 530 540 550 560
270 280 290 300
pF1KE4 KRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV
::
CCDS54 KRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSMTIETV
570 580 590 600 610 620
>>CCDS8509.1 FBXL14 gene_id:144699|Hs108|chr12 (418 aa)
initn: 221 init1: 117 opt: 269 Z-score: 319.0 bits: 67.5 E(32554): 1.9e-11
Smith-Waterman score: 269; 26.8% identity (64.7% similar) in 224 aa overlap (53-269:111-328)
30 40 50 60 70 80
pF1KE4 PWEDVLLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARL
..:: ....:: .. . . :: ..:.:.
CCDS85 SLSYVIQGMANIESLNLSGCYNLTDNGLGHAFVQ-EIGSLRALNLS-LCKQITDSSLGRI
90 100 110 120 130
90 100 110 120 130
pF1KE4 LRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALA------
. .::. : :. : . ... :. . .:.:. : .: .:: ..: ::
CCDS85 AQYLKGLEVLELGGCSN-ITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSA
140 150 160 170 180 190
140 150 160 170 180 190
pF1KE4 -EGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGL
::: :..:.: :. . :.:. .. .:. :.:. : ..: ....:.. ..:
CCDS85 AEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHM--GSL
200 210 220 230 240 250
200 210 220 230 240 250
pF1KE4 RSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHC
:::.: :..:.....:: . .: ::.. : .::.... .:. :.:: . :
CCDS85 RSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSLSLCSC
260 270 280 290 300 310
260 270 280 290 300
pF1KE4 HHVAESSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV
: .......:. ..
CCDS85 H-ISDDGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGL
320 330 340 350 360 370
>>CCDS54116.1 FBXL20 gene_id:84961|Hs108|chr17 (404 aa)
initn: 476 init1: 193 opt: 264 Z-score: 313.3 bits: 66.4 E(32554): 4e-11
Smith-Waterman score: 305; 29.3% identity (62.6% similar) in 198 aa overlap (73-267:149-344)
50 60 70 80 90 100
pF1KE4 RLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLS
:. . .. :.: ::. : : : . :
CCDS54 IEVLNLNGCTKTTDAEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQ-LE
120 130 140 150 160 170
110 120 130 140 150 160
pF1KE4 DEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLA
:: : . :. :.: .. : : :.. ..: .. .:: .:: : . :. . : .:.
CCDS54 DEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALG
180 190 200 210 220 230
170 180 190 200 210 220
pF1KE4 DRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELH
. :: :. :... : :: : ... :: : :....: ... :... .:. .::.:.
CCDS54 QNCPRLRILEVARCSQLTDVGFTTLA-RNCHELEKMDLEECVQITDSTLIQLSIHCPRLQ
240 250 260 270 280 290
230 240 250 260 270
pF1KE4 HLDLTGCLRVGSDGVRTLAE-YCP--VLRSLRVRHCHHVAESSLSRLRKRGVDIDVEPPL
:.:. : . .::.: :.. : :. ... .: ....:: .:.
CCDS54 VLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYD
300 310 320 330 340 350
280 290 300
pF1KE4 HQALVLLQDMAGFAPFVNLQV
CCDS54 CQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL
360 370 380 390 400
>>CCDS32640.1 FBXL20 gene_id:84961|Hs108|chr17 (436 aa)
initn: 515 init1: 193 opt: 264 Z-score: 312.8 bits: 66.5 E(32554): 4.2e-11
Smith-Waterman score: 305; 29.3% identity (62.6% similar) in 198 aa overlap (73-267:181-376)
50 60 70 80 90 100
pF1KE4 RLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLS
:. . .. :.: ::. : : : . :
CCDS32 ASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQ-LE
160 170 180 190 200
110 120 130 140 150 160
pF1KE4 DEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLA
:: : . :. :.: .. : : :.. ..: .. .:: .:: : . :. . : .:.
CCDS32 DEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALG
210 220 230 240 250 260
170 180 190 200 210 220
pF1KE4 DRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELH
. :: :. :... : :: : ... :: : :....: ... :... .:. .::.:.
CCDS32 QNCPRLRILEVARCSQLTDVGFTTLA-RNCHELEKMDLEECVQITDSTLIQLSIHCPRLQ
270 280 290 300 310 320
230 240 250 260 270
pF1KE4 HLDLTGCLRVGSDGVRTLAE-YCP--VLRSLRVRHCHHVAESSLSRLRKRGVDIDVEPPL
:.:. : . .::.: :.. : :. ... .: ....:: .:.
CCDS32 VLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYD
330 340 350 360 370 380
280 290 300
pF1KE4 HQALVLLQDMAGFAPFVNLQV
CCDS32 CQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL
390 400 410 420 430
>>CCDS54560.1 FBXL2 gene_id:25827|Hs108|chr3 (355 aa)
initn: 186 init1: 180 opt: 259 Z-score: 308.1 bits: 65.3 E(32554): 7.7e-11
Smith-Waterman score: 259; 26.8% identity (60.1% similar) in 228 aa overlap (44-267:96-320)
20 30 40 50 60 70
pF1KE4 PGAVRFLDLPWEDVLLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLAGLRRF-DAAQVGP
:. .. :.. .:.: : .. :.. .
CCDS54 GRVVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSL
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE4 QIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRAL
. . : .. . : : : : . ..:: .: . .:... :.::..:. .:
CCDS54 SRFCSKLKHIQNYCHELVSLNLQSCSR-ITDEGVVQICRGCHRLQALCLSGCSNLTDASL
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE4 GALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRG
::. .::::: : :.:. . .. :: : ::..:: : . : ... :. .
CCDS54 TALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIH-C
190 200 210 220 230 240
200 210 220 230 240
pF1KE4 AGLRSLSLAVNANVGDAAVQELARN-C--PELHHLDLTGCLRVGSDGVRTLAEYCPVLRS
:..:::. . : .. .:. . : .:. :.: .:: . . ... : : : :.
CCDS54 PKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHL-ENCRGLER
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE4 LRVRHCHHVAESSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV
:.. :..:......:.:
CCDS54 LELYDCQQVTRAGIKRMRAQLPHVKVHAYFAPVTPPTAVAGSGQRLCRCCVIL
310 320 330 340 350
300 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:32:44 2016 done: Sun Nov 6 03:32:45 2016
Total Scan time: 2.820 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]