Result of FASTA (omim) for
pFN21AE4039
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4039, 258 aa
1>>>pF1KE4039 258 - 258 aa - 258 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9971+/-0.000419; mu= 18.5736+/- 0.026
mean_var=141.9051+/-31.383, 0's: 0 Z-trim(114.0): 189 B-trim: 37 in 1/49
Lambda= 0.107665
statistics sampled from 23443 (23658) to 23443 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.277), width: 16
Scan time: 6.640
The best scores are: opt bits E(85289)
NP_001153695 (OMIM: 608984,614649) E3 ubiquitin-pr ( 258) 1742 282.1 6.9e-76
XP_006716467 (OMIM: 608984,614649) PREDICTED: E3 u ( 258) 1742 282.1 6.9e-76
XP_011542968 (OMIM: 608984,614649) PREDICTED: E3 u ( 258) 1742 282.1 6.9e-76
NP_112216 (OMIM: 608984,614649) E3 ubiquitin-prote ( 258) 1742 282.1 6.9e-76
XP_016869370 (OMIM: 608984,614649) PREDICTED: E3 u ( 258) 1742 282.1 6.9e-76
NP_001153697 (OMIM: 608984,614649) E3 ubiquitin-pr ( 174) 1216 200.1 2.2e-51
XP_016869371 (OMIM: 608984,614649) PREDICTED: E3 u ( 174) 1216 200.1 2.2e-51
NP_001153696 (OMIM: 608984,614649) E3 ubiquitin-pr ( 200) 907 152.2 6.6e-37
XP_006716468 (OMIM: 608984,614649) PREDICTED: E3 u ( 208) 835 141.1 1.6e-33
>>NP_001153695 (OMIM: 608984,614649) E3 ubiquitin-protei (258 aa)
initn: 1742 init1: 1742 opt: 1742 Z-score: 1483.5 bits: 282.1 E(85289): 6.9e-76
Smith-Waterman score: 1742; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258)
10 20 30 40 50 60
pF1KE4 MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFRNVHQNIHPENQELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFRNVHQNIHPENQELV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAYWRYGSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAYWRYGSW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERIMDLPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERIMDLPTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDFFVIFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDFFVIFLL
190 200 210 220 230 240
250
pF1KE4 LIYISIMYREVITQRLTR
::::::::::::::::::
NP_001 LIYISIMYREVITQRLTR
250
>>XP_006716467 (OMIM: 608984,614649) PREDICTED: E3 ubiqu (258 aa)
initn: 1742 init1: 1742 opt: 1742 Z-score: 1483.5 bits: 282.1 E(85289): 6.9e-76
Smith-Waterman score: 1742; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258)
10 20 30 40 50 60
pF1KE4 MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFRNVHQNIHPENQELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFRNVHQNIHPENQELV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAYWRYGSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAYWRYGSW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERIMDLPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERIMDLPTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDFFVIFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDFFVIFLL
190 200 210 220 230 240
250
pF1KE4 LIYISIMYREVITQRLTR
::::::::::::::::::
XP_006 LIYISIMYREVITQRLTR
250
>>XP_011542968 (OMIM: 608984,614649) PREDICTED: E3 ubiqu (258 aa)
initn: 1742 init1: 1742 opt: 1742 Z-score: 1483.5 bits: 282.1 E(85289): 6.9e-76
Smith-Waterman score: 1742; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258)
10 20 30 40 50 60
pF1KE4 MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFRNVHQNIHPENQELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFRNVHQNIHPENQELV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAYWRYGSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAYWRYGSW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERIMDLPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERIMDLPTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDFFVIFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDFFVIFLL
190 200 210 220 230 240
250
pF1KE4 LIYISIMYREVITQRLTR
::::::::::::::::::
XP_011 LIYISIMYREVITQRLTR
250
>>NP_112216 (OMIM: 608984,614649) E3 ubiquitin-protein l (258 aa)
initn: 1742 init1: 1742 opt: 1742 Z-score: 1483.5 bits: 282.1 E(85289): 6.9e-76
Smith-Waterman score: 1742; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258)
10 20 30 40 50 60
pF1KE4 MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFRNVHQNIHPENQELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFRNVHQNIHPENQELV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAYWRYGSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 RVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAYWRYGSW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERIMDLPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 LGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERIMDLPTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDFFVIFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 LRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDFFVIFLL
190 200 210 220 230 240
250
pF1KE4 LIYISIMYREVITQRLTR
::::::::::::::::::
NP_112 LIYISIMYREVITQRLTR
250
>>XP_016869370 (OMIM: 608984,614649) PREDICTED: E3 ubiqu (258 aa)
initn: 1742 init1: 1742 opt: 1742 Z-score: 1483.5 bits: 282.1 E(85289): 6.9e-76
Smith-Waterman score: 1742; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258)
10 20 30 40 50 60
pF1KE4 MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFRNVHQNIHPENQELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFRNVHQNIHPENQELV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAYWRYGSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAYWRYGSW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERIMDLPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERIMDLPTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDFFVIFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDFFVIFLL
190 200 210 220 230 240
250
pF1KE4 LIYISIMYREVITQRLTR
::::::::::::::::::
XP_016 LIYISIMYREVITQRLTR
250
>>NP_001153697 (OMIM: 608984,614649) E3 ubiquitin-protei (174 aa)
initn: 1216 init1: 1216 opt: 1216 Z-score: 1043.6 bits: 200.1 E(85289): 2.2e-51
Smith-Waterman score: 1216; 100.0% identity (100.0% similar) in 174 aa overlap (85-258:1-174)
60 70 80 90 100 110
pF1KE4 ENQELVRVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAY
::::::::::::::::::::::::::::::
NP_001 MYCPICLHQASFPVETNCGHLFCGACIIAY
10 20 30
120 130 140 150 160 170
pF1KE4 WRYGSWLGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRYGSWLGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERI
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE4 MDLPTLLRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDLPTLLRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDF
100 110 120 130 140 150
240 250
pF1KE4 FVIFLLLIYISIMYREVITQRLTR
::::::::::::::::::::::::
NP_001 FVIFLLLIYISIMYREVITQRLTR
160 170
>>XP_016869371 (OMIM: 608984,614649) PREDICTED: E3 ubiqu (174 aa)
initn: 1216 init1: 1216 opt: 1216 Z-score: 1043.6 bits: 200.1 E(85289): 2.2e-51
Smith-Waterman score: 1216; 100.0% identity (100.0% similar) in 174 aa overlap (85-258:1-174)
60 70 80 90 100 110
pF1KE4 ENQELVRVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAY
::::::::::::::::::::::::::::::
XP_016 MYCPICLHQASFPVETNCGHLFCGACIIAY
10 20 30
120 130 140 150 160 170
pF1KE4 WRYGSWLGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WRYGSWLGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERI
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE4 MDLPTLLRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDLPTLLRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDF
100 110 120 130 140 150
240 250
pF1KE4 FVIFLLLIYISIMYREVITQRLTR
::::::::::::::::::::::::
XP_016 FVIFLLLIYISIMYREVITQRLTR
160 170
>>NP_001153696 (OMIM: 608984,614649) E3 ubiquitin-protei (200 aa)
initn: 907 init1: 907 opt: 907 Z-score: 783.6 bits: 152.2 E(85289): 6.6e-37
Smith-Waterman score: 907; 100.0% identity (100.0% similar) in 132 aa overlap (1-132:1-132)
10 20 30 40 50 60
pF1KE4 MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFRNVHQNIHPENQELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFRNVHQNIHPENQELV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAYWRYGSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAYWRYGSW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERIMDLPTL
::::::::::::
NP_001 LGAISCPICRQTGSSEKSSRASEQTHQEAVACLDTQNSPACTVGCRSGPQHIPHDRMLPS
130 140 150 160 170 180
>>XP_006716468 (OMIM: 608984,614649) PREDICTED: E3 ubiqu (208 aa)
initn: 1095 init1: 835 opt: 835 Z-score: 723.0 bits: 141.1 E(85289): 1.6e-33
Smith-Waterman score: 1006; 69.8% identity (74.8% similar) in 258 aa overlap (1-258:1-208)
10 20 30 40 50 60
pF1KE4 MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFRNVHQNIHPENQELV
:::::::::::::::::::::::::::::::::::::::::::::: .: . : ..
XP_006 MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFR-MH--LLPLDSS--
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 RVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAYWRYGSW
. . : . : .:: : :
XP_006 ----------------------STLTCTV-------P----------SACTKPPSR---W
60 70
130 140 150 160 170 180
pF1KE4 LGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERIMDLPTL
... . .::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RPTVDIFF---VVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERIMDLPTL
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE4 LRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDFFVIFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDFFVIFLL
140 150 160 170 180 190
250
pF1KE4 LIYISIMYREVITQRLTR
::::::::::::::::::
XP_006 LIYISIMYREVITQRLTR
200
258 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:41:34 2016 done: Sun Nov 6 03:41:35 2016
Total Scan time: 6.640 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]