Result of FASTA (ccds) for
pFN21AE4035
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4035, 246 aa
1>>>pF1KE4035 246 - 246 aa - 246 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1974+/-0.000637; mu= 15.8152+/- 0.038
mean_var=80.2784+/-15.909, 0's: 0 Z-trim(112.7): 24 B-trim: 4 in 1/50
Lambda= 0.143145
statistics sampled from 13378 (13400) to 13378 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.776), E-opt: 0.2 (0.412), width: 16
Scan time: 2.500
The best scores are: opt bits E(32554)
CCDS12202.1 MARCH2 gene_id:51257|Hs108|chr19 ( 246) 1726 365.3 2.2e-101
CCDS4141.1 MARCH3 gene_id:115123|Hs108|chr5 ( 253) 1085 232.9 1.6e-61
CCDS32894.1 MARCH2 gene_id:51257|Hs108|chr19 ( 176) 886 191.7 2.8e-49
CCDS7213.1 MARCH8 gene_id:220972|Hs108|chr10 ( 291) 327 76.4 2.3e-14
CCDS54814.1 MARCH1 gene_id:55016|Hs108|chr4 ( 289) 306 72.1 4.6e-13
CCDS60519.1 MARCH8 gene_id:220972|Hs108|chr10 ( 573) 309 72.9 5e-13
CCDS3806.1 MARCH1 gene_id:55016|Hs108|chr4 ( 272) 300 70.8 1e-12
>>CCDS12202.1 MARCH2 gene_id:51257|Hs108|chr19 (246 aa)
initn: 1726 init1: 1726 opt: 1726 Z-score: 1933.7 bits: 365.3 E(32554): 2.2e-101
Smith-Waterman score: 1726; 99.6% identity (100.0% similar) in 246 aa overlap (1-246:1-246)
10 20 30 40 50 60
pF1KE4 MTTGDCCHLPGSLCDCSGSPAFSKVVEATGLGPPQYVAQVTSRDGRLLSTVIRTLDTPSD
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
CCDS12 MTTGDCCHLPGSLCDCSGSPAFSKVVEATGLGPPQYVAQVTSRDGRLLSTVIRALDTPSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GPFCRICHEGANGECLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEFAVEKRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 GPFCRICHEGANGECLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEFAVEKRPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PLTEWLKDPGPRTEKRTLCCDMVCFLFITPLAAISGWLCLRGAQDHLRLHSQLEAVGLIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 PLTEWLKDPGPRTEKRTLCCDMVCFLFITPLAAISGWLCLRGAQDHLRLHSQLEAVGLIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 LTIALFTIYVLWTLVSFRYHCQLYSEWRKTNQKVRLKIREADSPEGPQHSPLAAGLLKKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LTIALFTIYVLWTLVSFRYHCQLYSEWRKTNQKVRLKIREADSPEGPQHSPLAAGLLKKV
190 200 210 220 230 240
pF1KE4 AEETPV
::::::
CCDS12 AEETPV
>>CCDS4141.1 MARCH3 gene_id:115123|Hs108|chr5 (253 aa)
initn: 1123 init1: 893 opt: 1085 Z-score: 1218.1 bits: 232.9 E(32554): 1.6e-61
Smith-Waterman score: 1085; 65.1% identity (82.0% similar) in 255 aa overlap (1-246:1-253)
10 20 30 40 50
pF1KE4 MTTGDCCHLPGSLCDCSGSPA-FSKVVEATGL---GPPQYVAQVTSRDGRLLSTVIRTLD
:::. : ::: : ::..: : :.:: : : :::: ::...::.:::::.:::
CCDS41 MTTSRCSHLPEVLPDCTSSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 TPS---DGPFCRICHEGANGECLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEF
: : : :.:::::::.. : ::::: ::::::..:.::::.:::::::::::::: .:
CCDS41 TQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCHFRF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 AVEKRPRPLTEWLKDPGPRTEKRTLCCDMVCFLFITPLAAISGWLCLRGAQDHLRLHSQL
:::..::::.:::..:::. ::::: ::::::::::::.:::::::::: :::.. :.:
CCDS41 AVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPLATISGWLCLRGAVDHLHFSSRL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE4 EAVGLIALTIALFTIYVLWTLVSFRYHCQLYSEWRKTNQKVRLKIREADSPEGPQHSPLA
:::::::::.::::::..::::::::::.::.:::.:::.: : : . : . :...:
CCDS41 EAVGLIALTVALFTIYLFWTLVSFRYHCRLYNEWRRTNQRVILLIPK--SVNVPSNQPSL
190 200 210 220 230
240
pF1KE4 AGL--LKKVAEETPV
:: .:. ..:: :
CCDS41 LGLHSVKRNSKETVV
240 250
>>CCDS32894.1 MARCH2 gene_id:51257|Hs108|chr19 (176 aa)
initn: 886 init1: 886 opt: 886 Z-score: 998.1 bits: 191.7 E(32554): 2.8e-49
Smith-Waterman score: 1088; 71.1% identity (71.5% similar) in 246 aa overlap (1-246:1-176)
10 20 30 40 50 60
pF1KE4 MTTGDCCHLPGSLCDCSGSPAFSKVVEATGLGPPQYVAQVTSRDGRLLSTVIRTLDTPSD
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
CCDS32 MTTGDCCHLPGSLCDCSGSPAFSKVVEATGLGPPQYVAQVTSRDGRLLSTVIRALDTPSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 GPFCRICHEGANGECLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEFAVEKRPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 GPFCRICHEGANGECLLSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEFAVEKRPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 PLTEWLKDPGPRTEKRTLCCDMVCFLFITPLAAISGWLCLRGAQDHLRLHSQLEAVGLIA
::::
CCDS32 PLTE--------------------------------------------------------
190 200 210 220 230 240
pF1KE4 LTIALFTIYVLWTLVSFRYHCQLYSEWRKTNQKVRLKIREADSPEGPQHSPLAAGLLKKV
::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 --------------VSFRYHCQLYSEWRKTNQKVRLKIREADSPEGPQHSPLAAGLLKKV
130 140 150 160 170
pF1KE4 AEETPV
::::::
CCDS32 AEETPV
>>CCDS7213.1 MARCH8 gene_id:220972|Hs108|chr10 (291 aa)
initn: 283 init1: 223 opt: 327 Z-score: 371.3 bits: 76.4 E(32554): 2.3e-14
Smith-Waterman score: 327; 30.4% identity (62.0% similar) in 184 aa overlap (48-225:64-243)
20 30 40 50 60 70
pF1KE4 GSPAFSKVVEATGLGPPQYVAQVTSRDGRLLSTVIRTLDTPSDGPFCRICH-EGANGECL
.:. :: :::. .::::: :: . :
CCDS72 QNEKTLGHFMSHSSNISKAGSPPSASAPAPVSSFSRTSITPSSQDICRICHCEGDDESPL
40 50 60 70 80 90
80 90 100 110 120 130
pF1KE4 LSPCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEFAVEKRPRPLTEWLKDPGPRTEKR
..:: :::.: ::..::..:..::.: ::::. :: .: . .:: .: : .:.:
CCDS72 ITPCHCTGSLHFVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSSERR
100 110 120 130 140 150
140 150 160 170 180 190
pF1KE4 TLCCDMVCFLFITPLAAISGWLCLRGAQDHLRLHSQLEAVGLIALTI--ALFTIYVLWT-
. :... .. .. : .. . . .... : .:.:.. . : .. . .:
CCDS72 KIMCSVTFHVIAITCVVWSLYVLIDRTAEEIK---QGQATGILEWPFWTKLVVVAIGFTG
160 170 180 190 200 210
200 210 220 230 240
pF1KE4 -LVSFRYHCQLYSE-WRKTNQKVRLKIREADSPEGPQHSPLAAGLLKKVAEETPV
:. . .:..: . :.. . :. : . ::
CCDS72 GLLFMYVQCKVYVQLWKRLKAYNRV-IYVQNCPETSKKNIFEKSPLTEPNFENKHGYGIC
220 230 240 250 260
CCDS72 HSDTNSSCCTEPEDTGAEIIHV
270 280 290
>>CCDS54814.1 MARCH1 gene_id:55016|Hs108|chr4 (289 aa)
initn: 265 init1: 220 opt: 306 Z-score: 347.9 bits: 72.1 E(32554): 4.6e-13
Smith-Waterman score: 306; 26.8% identity (59.2% similar) in 213 aa overlap (9-216:24-235)
10 20 30 40
pF1KE4 MTTGDCCHLPGSLCDCSGSPAFSKVVEATGLGPPQYVAQVTS-RD
. :.: : : . .... . . . . .....:
CCDS54 MLGWCEAIARNPHRIPNNTRTPEISGDLADASQTSTLNEKSPGRSASRSSNISKASSPTT
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 GRLLSTVIRTLDTPSDGPFCRICH-EGANGECLLSPCGCTGTLGAVHKSCLEKWLSSSNT
: . : :: .::::: :: . :..:: ::::: ::.:::..:..::.:
CCDS54 GTAPRSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDT
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 SYCELCHTEFAVEKRPRPLTEWLKDPGPRTEKRTLCCDMVCFLFITPLAAISGWLCLRGA
::::. .: .: . .:: .: : .:.: . :... .. .. : .. . .
CCDS54 RCCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHVIAITCVVWSLYVLIDRT
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE4 QDHLRLHSQLEAVGLIALTIALFTIYVLWT--LVSFRYHCQLYSE-WRKTNQKVRLKIRE
.... ... ..: . : .. . .: :: . .:..: . ::. . :.
CCDS54 AEEIK-QGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQ
190 200 210 220 230
230 240
pF1KE4 ADSPEGPQHSPLAAGLLKKVAEETPV
CCDS54 NCPDTAKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGGPPEVVSV
240 250 260 270 280
>>CCDS60519.1 MARCH8 gene_id:220972|Hs108|chr10 (573 aa)
initn: 289 init1: 223 opt: 309 Z-score: 347.3 bits: 72.9 E(32554): 5e-13
Smith-Waterman score: 309; 29.5% identity (61.8% similar) in 173 aa overlap (59-225:357-525)
30 40 50 60 70 80
pF1KE4 TGLGPPQYVAQVTSRDGRLLSTVIRTLDTPSDGPFCRICH-EGANGECLLSPCGCTGTLG
..: ::::: :: . :..:: :::.:
CCDS60 RAPLCSTEKDSDLDCPSPFSEKLPPISPVSTSGDVCRICHCEGDDESPLITPCHCTGSLH
330 340 350 360 370 380
90 100 110 120 130 140
pF1KE4 AVHKSCLEKWLSSSNTSYCELCHTEFAVEKRPRPLTEWLKDPGPRTEKRTLCCDMVCFLF
::..::..:..::.: ::::. :: .: . .:: .: : .:.: . :... ..
CCDS60 FVHQACLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVI
390 400 410 420 430 440
150 160 170 180 190 200
pF1KE4 ITPLAAISGWLCLRGAQDHLRLHSQLEAVGLIALTI--ALFTIYVLWT--LVSFRYHCQL
.. : .. . . .... : .:.:.. . : .. . .: :. . .:..
CCDS60 AITCVVWSLYVLIDRTAEEIK---QGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKV
450 460 470 480 490 500
210 220 230 240
pF1KE4 YSE-WRKTNQKVRLKIREADSPEGPQHSPLAAGLLKKVAEETPV
: . :.. . :. : . ::
CCDS60 YVQLWKRLKAYNRV-IYVQNCPETSKKNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTE
510 520 530 540 550 560
>>CCDS3806.1 MARCH1 gene_id:55016|Hs108|chr4 (272 aa)
initn: 265 init1: 220 opt: 300 Z-score: 341.6 bits: 70.8 E(32554): 1e-12
Smith-Waterman score: 300; 30.7% identity (62.6% similar) in 163 aa overlap (58-216:57-218)
30 40 50 60 70 80
pF1KE4 ATGLGPPQYVAQVTSRDGRLLSTVIRTLDTPSDGPFCRICH-EGANGECLLSPCGCTGTL
:: .::::: :: . :..:: :::::
CCDS38 QDAKLSNLFLQASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTL
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE4 GAVHKSCLEKWLSSSNTSYCELCHTEFAVEKRPRPLTEWLKDPGPRTEKRTLCCDMVCFL
::.:::..:..::.: ::::. .: .: . .:: .: : .:.: . :... .
CCDS38 RFVHQSCLHQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIFCSVTFHV
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE4 FITPLAAISGWLCLRGAQDHLRLHSQLEAVGLIALTIALFTIYVLWT--LVSFRYHCQLY
. .. : .. . . .... ... ..: . : .. . .: :: . .:..:
CCDS38 IAITCVVWSLYVLIDRTAEEIK-QGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVY
150 160 170 180 190 200
210 220 230 240
pF1KE4 SE-WRKTNQKVRLKIREADSPEGPQHSPLAAGLLKKVAEETPV
. ::. . :.
CCDS38 VQLWRRLKAYNRVIFVQNCPDTAKKLEKNFSCNVNTDIKDAVVVPVPQTGANSLPSAEGG
210 220 230 240 250 260
246 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 01:45:53 2016 done: Sun Nov 6 01:45:53 2016
Total Scan time: 2.500 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]