Result of FASTA (ccds) for
pFN21AE4034
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4034, 244 aa
1>>>pF1KE4034 244 - 244 aa - 244 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5305+/-0.000703; mu= 14.2024+/- 0.043
mean_var=86.2096+/-17.635, 0's: 0 Z-trim(112.8): 53 B-trim: 818 in 2/48
Lambda= 0.138133
statistics sampled from 13412 (13477) to 13412 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.778), E-opt: 0.2 (0.414), width: 16
Scan time: 2.460
The best scores are: opt bits E(32554)
CCDS4400.1 ARL10 gene_id:285598|Hs108|chr5 ( 244) 1655 338.9 1.9e-93
CCDS7538.1 ARL3 gene_id:403|Hs108|chr10 ( 182) 320 72.7 1.8e-13
CCDS9695.1 ARF6 gene_id:382|Hs108|chr14 ( 175) 313 71.3 4.7e-13
CCDS44958.1 ARL1 gene_id:400|Hs108|chr12 ( 181) 313 71.4 4.8e-13
CCDS2566.1 ARL8B gene_id:55207|Hs108|chr3 ( 186) 307 70.2 1.1e-12
CCDS59474.1 ARL9 gene_id:132946|Hs108|chr4 ( 123) 304 69.4 1.2e-12
CCDS1421.1 ARL8A gene_id:127829|Hs108|chr1 ( 186) 302 69.2 2.2e-12
CCDS8088.1 ARL2 gene_id:402|Hs108|chr11 ( 184) 298 68.4 3.8e-12
CCDS2884.1 ARF4 gene_id:378|Hs108|chr3 ( 180) 297 68.2 4.3e-12
CCDS8774.1 ARF3 gene_id:377|Hs108|chr12 ( 181) 295 67.8 5.7e-12
CCDS1565.1 ARF1 gene_id:375|Hs108|chr1 ( 181) 295 67.8 5.7e-12
CCDS34745.1 ARF5 gene_id:381|Hs108|chr7 ( 180) 291 67.0 9.9e-12
CCDS5359.1 ARL4A gene_id:10124|Hs108|chr7 ( 200) 289 66.6 1.4e-11
CCDS11463.1 ARL4D gene_id:379|Hs108|chr17 ( 201) 287 66.2 1.9e-11
CCDS9419.1 ARL11 gene_id:115761|Hs108|chr13 ( 196) 284 65.6 2.8e-11
>>CCDS4400.1 ARL10 gene_id:285598|Hs108|chr5 (244 aa)
initn: 1655 init1: 1655 opt: 1655 Z-score: 1791.3 bits: 338.9 E(32554): 1.9e-93
Smith-Waterman score: 1655; 100.0% identity (100.0% similar) in 244 aa overlap (1-244:1-244)
10 20 30 40 50 60
pF1KE4 MAPRPLGPLVLALGGAAAVLGSVLFILWKTYFGRGRERRWDRGEAWWGAEAARLPEWDEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MAPRPLGPLVLALGGAAAVLGSVLFILWKTYFGRGRERRWDRGEAWWGAEAARLPEWDEW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 DPEDEEDEEPALEELEQREVLVLGLDGAGKSTFLRVLSGKPPLEGHIPTWGFNSVRLPTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DPEDEEDEEPALEELEQREVLVLGLDGAGKSTFLRVLSGKPPLEGHIPTWGFNSVRLPTK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 DFEVDLLEIGGSQNLRFYWKEFVSEVDVLVFVVDSADRLRLPWARQELHKLLDKDPDLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DFEVDLLEIGGSQNLRFYWKEFVSEVDVLVFVVDSADRLRLPWARQELHKLLDKDPDLPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VVVANKQDLSEAMSMGELQRELGLQAIDNQREVFLLAASIAPAGPTFEEPGTVHIWKLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VVVANKQDLSEAMSMGELQRELGLQAIDNQREVFLLAASIAPAGPTFEEPGTVHIWKLLL
190 200 210 220 230 240
pF1KE4 ELLS
::::
CCDS44 ELLS
>>CCDS7538.1 ARL3 gene_id:403|Hs108|chr10 (182 aa)
initn: 314 init1: 201 opt: 320 Z-score: 355.2 bits: 72.7 E(32554): 1.8e-13
Smith-Waterman score: 320; 38.4% identity (74.6% similar) in 138 aa overlap (76-210:16-151)
50 60 70 80 90 100
pF1KE4 WWGAEAARLPEWDEWDPEDEEDEEPALEELEQREVLVLGLDGAGKSTFLRVLSGKPPLEG
.. ..:.::::.:::.:.:. :... .
CCDS75 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDI--S
10 20 30 40
110 120 130 140 150 160
pF1KE4 HI-PTWGFNSVRLPTKDFEVDLLEIGGSQNLRFYWKEFVSEVDVLVFVVDSADRLRLPWA
:: :: ::: . .. :.... .:::....: :::.. ..:.:..:.::::: :. .
CCDS75 HITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEET
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 RQELHKLLDKDPD--LPVVVVANKQDLSEAMSMGELQRELGLQAIDNQREVFLLAASIAP
::: .::... .::.. :::::: : .:. . :.:..: ..
CCDS75 GQELAELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTG
110 120 130 140 150 160
230 240
pF1KE4 AGPTFEEPGTVHIWKLLLELLS
CCDS75 EGVQDGMNWVCKNVNAKKK
170 180
>>CCDS9695.1 ARF6 gene_id:382|Hs108|chr14 (175 aa)
initn: 310 init1: 186 opt: 313 Z-score: 347.9 bits: 71.3 E(32554): 4.7e-13
Smith-Waterman score: 313; 37.8% identity (67.3% similar) in 156 aa overlap (76-229:13-164)
50 60 70 80 90 100
pF1KE4 WWGAEAARLPEWDEWDPEDEEDEEPALEELEQREVLVLGLDGAGKSTFLRVLSGKPPLEG
:.: .:.::::.:::.:.: :. .
CCDS96 MGKVLSKIFGNKEMR-ILMLGLDAAGKTTILYKLKLGQSVTT
10 20 30 40
110 120 130 140 150 160
pF1KE4 HIPTWGFNSVRLPTKDFEVDLLEIGGSQNLRFYWKEFVSEVDVLVFVVDSADRLRLPWAR
::: ::: . :. . .. ..::....: :... . .. :.:::: ::: :. ::
CCDS96 -IPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEAR
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 QELHKLL-DKDP-DLPVVVVANKQDLSEAMSMGELQRELGLQAIDNQREVFLLAASIAPA
::::... :.. : ... :::::: .::. :.:..::: : .. . . : : .
CCDS96 QELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRN--WYVQPSCATS
110 120 130 140 150
230 240
pF1KE4 GPTFEEPGTVHIWKLLLELLS
: . :
CCDS96 GDGLYEGLTWLTSNYKS
160 170
>>CCDS44958.1 ARL1 gene_id:400|Hs108|chr12 (181 aa)
initn: 310 init1: 165 opt: 313 Z-score: 347.7 bits: 71.4 E(32554): 4.8e-13
Smith-Waterman score: 313; 37.8% identity (69.6% similar) in 148 aa overlap (76-219:17-161)
50 60 70 80 90 100
pF1KE4 WWGAEAARLPEWDEWDPEDEEDEEPALEELEQREVLVLGLDGAGKSTFL-RVLSGKPPLE
:.: .:.::::::::.:.: :. :. .
CCDS44 MGGFFSSIFSSLFGTREMR-ILILGLDGAGKTTILYRLQVGE--VV
10 20 30 40
110 120 130 140 150 160
pF1KE4 GHIPTWGFNSVRLPTKDFEVDLLEIGGSQNLRFYWKEFVSEVDVLVFVVDSADRLRLPWA
::: ::: . :... .. ..::. ..: ::. . :..:....:::: :: :. .
CCDS44 TTIPTIGFNVETVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGIS
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 RQELHKLLDKDP--DLPVVVVANKQDLSEAMSMGELQRELGLQAI-DNQREVFLLAASIA
..:: .:... .:: :::::. .::. .:. ::: :. : . ..: .:.
CCDS44 KSELVAMLEEEELRKAILVVFANKQDMEQAMTSSEMANSLGLPALKDRKWQIFKTSATKG
110 120 130 140 150 160
230 240
pF1KE4 PAGPTFEEPGTVHIWKLLLELLS
CCDS44 TGLDEAMEWLVETLKSRQ
170 180
>>CCDS2566.1 ARL8B gene_id:55207|Hs108|chr3 (186 aa)
initn: 302 init1: 238 opt: 307 Z-score: 341.1 bits: 70.2 E(32554): 1.1e-12
Smith-Waterman score: 307; 36.2% identity (73.0% similar) in 141 aa overlap (76-213:19-157)
50 60 70 80 90 100
pF1KE4 WWGAEAARLPEWDEWDPEDEEDEEPALEELEQREVLVLGLDGAGKSTFLRVLSGKPPLEG
:. :. ..::. .::.::. :... :
CCDS25 MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSED
10 20 30 40
110 120 130 140 150 160
pF1KE4 HIPTWGFNSVRLPTKDFEVDLLEIGGSQNLRFYWKEFVSEVDVLVFVVDSADRLRLPWAR
::: ::: .. . . . .:::. .: .:... :...:...:.::: .. .:
CCDS25 MIPTVGFNMRKVTKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASR
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 QELHKLLDKDPDL---PVVVVANKQDLSEAMSMGELQRELGLQAIDNQREVFLLAASIAP
.:::.:::: :.: ::.:..::.:: .:.. .: ....:.::.. ::.
CCDS25 NELHNLLDK-PQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQD-REICCYSISCKE
110 120 130 140 150 160
230 240
pF1KE4 AGPTFEEPGTVHIWKLLLELLS
CCDS25 KDNIDITLQWLIQHSKSRRS
170 180
>>CCDS59474.1 ARL9 gene_id:132946|Hs108|chr4 (123 aa)
initn: 324 init1: 291 opt: 304 Z-score: 340.3 bits: 69.4 E(32554): 1.2e-12
Smith-Waterman score: 304; 41.3% identity (74.4% similar) in 121 aa overlap (124-244:1-119)
100 110 120 130 140 150
pF1KE4 LRVLSGKPPLEGHIPTWGFNSVRLPTKDFEVDLLEIGGSQNLRFYWKEFVSEVDVLVFVV
...::::::. .: ::. ..:. .:.:::
CCDS59 MEFLEIGGSKPFRSYWEMYLSKGLLLIFVV
10 20 30
160 170 180 190 200 210
pF1KE4 DSADRLRLPWARQELHKLLDKDPDLPVVVVANKQDLSEAMSMGELQRELGLQAIDNQREV
::::. ::: :.. ::.:. .: ::.:: :::::: :. . .... :.:. . :.:..
CCDS59 DSADHSRLPEAKKYLHQLIAANPVLPLVVFANKQDLEAAYHITDIHEALALSEVGNDRKM
40 50 60 70 80 90
220 230 240
pF1KE4 FLLAASIAPAGPTFEEPGTVHIWKLLLELLS
::... .. : : :.:.. : :. :.
CCDS59 FLFGTYLTKNGS--EIPSTMQDAKDLIAQLAADVQ
100 110 120
>>CCDS1421.1 ARL8A gene_id:127829|Hs108|chr1 (186 aa)
initn: 296 init1: 231 opt: 302 Z-score: 335.7 bits: 69.2 E(32554): 2.2e-12
Smith-Waterman score: 302; 36.7% identity (70.0% similar) in 150 aa overlap (67-213:10-157)
40 50 60 70 80 90
pF1KE4 ERRWDRGEAWWGAEAARLPEWDEWDPEDEEDEEPALEELEQREVLVLGLDGAGKSTFLRV
: :: :. :. ..::. .::.::. :
CCDS14 MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNV
10 20 30
100 110 120 130 140 150
pF1KE4 LSGKPPLEGHIPTWGFNSVRLPTKDFEVDLLEIGGSQNLRFYWKEFVSEVDVLVFVVDSA
... : ::: ::: .. . . : .:::. .: .:... :...:..::.:
CCDS14 IASGQFNEDMIPTVGFNMRKITKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAA
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE4 DRLRLPWARQELHKLLDKDPDL---PVVVVANKQDLSEAMSMGELQRELGLQAIDNQREV
:. .. ...:::.:::: :.: ::.:..::.:: :.. :: ....:.::.. ::.
CCDS14 DQEKIEASKNELHNLLDK-PQLQGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQD-REI
100 110 120 130 140 150
220 230 240
pF1KE4 FLLAASIAPAGPTFEEPGTVHIWKLLLELLS
CCDS14 CCYSISCKEKDNIDITLQWLIQHSKSRRS
160 170 180
>>CCDS8088.1 ARL2 gene_id:402|Hs108|chr11 (184 aa)
initn: 285 init1: 188 opt: 298 Z-score: 331.5 bits: 68.4 E(32554): 3.8e-12
Smith-Waterman score: 298; 36.6% identity (71.1% similar) in 142 aa overlap (72-207:7-147)
50 60 70 80 90
pF1KE4 RGEAWWGAEAARLPEWDEWDPEDEEDEEPALEELEQRE----VLVLGLDGAGKSTFLRVL
:....:.: .:.::::.:::.:.:. .
CCDS80 MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKF
10 20 30
100 110 120 130 140 150
pF1KE4 SGKPPLEGHIPTWGFNSVRLPTKDFEVDLLEIGGSQNLRFYWKEFVSEVDVLVFVVDSAD
.:. .. :: ::: : . :.... ..::...:: ::... .: :..::::::
CCDS80 NGED-IDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSAD
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE4 RLRLPWARQELHKLL--DKDPDLPVVVVANKQDLSEAMSMGELQRELGLQAIDNQREVFL
: :. ..::..:: .. ... :::::: :.: . ... : :..:
CCDS80 RQRMQDCQRELQSLLVEERLAGATLLIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQ
100 110 120 130 140 150
220 230 240
pF1KE4 LAASIAPAGPTFEEPGTVHIWKLLLELLS
CCDS80 GCSAVTGENLLPGIDWLLDDISSRIFTAD
160 170 180
>>CCDS2884.1 ARF4 gene_id:378|Hs108|chr3 (180 aa)
initn: 277 init1: 159 opt: 297 Z-score: 330.5 bits: 68.2 E(32554): 4.3e-12
Smith-Waterman score: 297; 36.3% identity (68.2% similar) in 157 aa overlap (76-229:16-168)
50 60 70 80 90 100
pF1KE4 WWGAEAARLPEWDEWDPEDEEDEEPALEELEQREVLVLGLDGAGKSTFLRVLS-GKPPLE
.: ..:..:::.:::.:.: :. :. .
CCDS28 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGE--IV
10 20 30 40
110 120 130 140 150 160
pF1KE4 GHIPTWGFNSVRLPTKDFEVDLLEIGGSQNLRFYWKEFVSEVDVLVFVVDSADRLRLPWA
::: ::: . :.. . ..::.. .: ::.. .... :.::::: :: :. .
CCDS28 TTIPTIGFNVETVEYKNICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEV
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 RQELHKLL--DKDPDLPVVVVANKQDLSEAMSMGELQRELGLQAIDNQREVFLLAASIAP
.::.:.: :. : ... :::::: .::...:. .::::.. :. .. . :. :
CCDS28 ADELQKMLLVDELRDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNR--TWYVQATCAT
110 120 130 140 150 160
230 240
pF1KE4 AGPTFEEPGTVHIWKLLLELLS
: . :
CCDS28 QGTGLYEGLDWLSNELSKR
170 180
>>CCDS8774.1 ARF3 gene_id:377|Hs108|chr12 (181 aa)
initn: 277 init1: 175 opt: 295 Z-score: 328.3 bits: 67.8 E(32554): 5.7e-12
Smith-Waterman score: 295; 36.3% identity (68.2% similar) in 157 aa overlap (76-229:17-168)
50 60 70 80 90 100
pF1KE4 WWGAEAARLPEWDEWDPEDEEDEEPALEELEQREVLVLGLDGAGKSTFLRVLS-GKPPLE
:.: .:..:::.:::.:.: :. :. .
CCDS87 MGNIFGNLLKSLIGKKEMR-ILMVGLDAAGKTTILYKLKLGE--IV
10 20 30 40
110 120 130 140 150 160
pF1KE4 GHIPTWGFNSVRLPTKDFEVDLLEIGGSQNLRFYWKEFVSEVDVLVFVVDSADRLRLPWA
::: ::: . :.. . ..::....: :... .... :.::::: :: :. :
CCDS87 TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEA
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE4 RQELHKLLDKDP--DLPVVVVANKQDLSEAMSMGELQRELGLQAIDNQREVFLLAASIAP
:.:: ..: .: : ..: :::::: .::. .:. .:::... .. . . :. :
CCDS87 REELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRN--WYIQATCAT
110 120 130 140 150 160
230 240
pF1KE4 AGPTFEEPGTVHIWKLLLELLS
.: . :
CCDS87 SGDGLYEGLDWLANQLKNKK
170 180
244 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 15:14:46 2016 done: Mon Nov 7 15:14:47 2016
Total Scan time: 2.460 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]