Result of FASTA (ccds) for
pFN21AE4029
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4029, 236 aa
1>>>pF1KE4029 236 - 236 aa - 236 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3930+/-0.000665; mu= 11.4182+/- 0.041
mean_var=115.9796+/-22.568, 0's: 0 Z-trim(115.5): 166 B-trim: 482 in 1/51
Lambda= 0.119092
statistics sampled from 15895 (16067) to 15895 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.817), E-opt: 0.2 (0.494), width: 16
Scan time: 2.700
The best scores are: opt bits E(32554)
CCDS10068.1 RHOV gene_id:171177|Hs108|chr15 ( 236) 1622 288.3 2.9e-78
CCDS1575.1 RHOU gene_id:58480|Hs108|chr1 ( 258) 889 162.4 2.5e-40
CCDS221.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 697 129.3 1.7e-30
CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 ( 192) 696 129.2 1.9e-30
CCDS222.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 695 129.0 2.2e-30
CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 ( 192) 695 129.0 2.2e-30
CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 ( 205) 695 129.0 2.3e-30
CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 ( 192) 690 128.1 4e-30
CCDS7748.1 RHOG gene_id:391|Hs108|chr11 ( 191) 627 117.3 7.1e-27
CCDS9757.1 RHOJ gene_id:57381|Hs108|chr14 ( 214) 618 115.8 2.3e-26
CCDS2795.1 RHOA gene_id:387|Hs108|chr3 ( 193) 552 104.4 5.4e-23
CCDS1699.1 RHOB gene_id:388|Hs108|chr2 ( 196) 552 104.4 5.5e-23
CCDS854.1 RHOC gene_id:389|Hs108|chr1 ( 193) 544 103.1 1.4e-22
CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 ( 210) 534 101.4 5e-22
CCDS3458.1 RHOH gene_id:399|Hs108|chr4 ( 191) 480 92.1 2.9e-19
CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 ( 211) 473 90.9 7.1e-19
CCDS82775.1 RHOA gene_id:387|Hs108|chr3 ( 187) 455 87.7 5.5e-18
CCDS2190.1 RND3 gene_id:390|Hs108|chr2 ( 244) 454 87.7 7.6e-18
CCDS8771.1 RND1 gene_id:27289|Hs108|chr12 ( 232) 414 80.8 8.6e-16
CCDS11452.1 RND2 gene_id:8153|Hs108|chr17 ( 227) 411 80.3 1.2e-15
CCDS5349.1 RAC1 gene_id:5879|Hs108|chr7 ( 211) 335 67.2 9.7e-12
>>CCDS10068.1 RHOV gene_id:171177|Hs108|chr15 (236 aa)
initn: 1622 init1: 1622 opt: 1622 Z-score: 1518.6 bits: 288.3 E(32554): 2.9e-78
Smith-Waterman score: 1622; 100.0% identity (100.0% similar) in 236 aa overlap (1-236:1-236)
10 20 30 40 50 60
pF1KE4 MPPRELSEAEPPPLRAPTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MPPRELSEAEPPPLRAPTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 RPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 RPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 ITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRA
130 140 150 160 170 180
190 200 210 220 230
pF1KE4 CCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 CCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV
190 200 210 220 230
>>CCDS1575.1 RHOU gene_id:58480|Hs108|chr1 (258 aa)
initn: 935 init1: 655 opt: 889 Z-score: 837.4 bits: 162.4 E(32554): 2.5e-40
Smith-Waterman score: 905; 54.4% identity (76.1% similar) in 259 aa overlap (1-236:1-258)
10 20 30 40
pF1KE4 MPPRELSEAEPPPLRAPTPPPRRRSA------PPE------------LGIKCVLVGDGAV
:::.. . : : .:: ::::. . : : :.::::::::::
CCDS15 MPPQQGDPAFPDRCEAPPVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 GKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPD
::.::.:::: ::::..: :::.:.::. : ::: :::..: :::::..::.:: ::: .
CCDS15 GKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTN
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 TDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGR
::.:: :::::.::::::..:::.:::: : :.::..:::::.:::.::.:::.::. .
CCDS15 TDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKC-K
130 140 150 160 170
170 180 190 200 210 220
pF1KE4 EGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKG--
: :::. :. ::.:.: :.:::::::::::::::.::...:... .. ..:.
CCDS15 EKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRT
180 190 200 210 220 230
230
pF1KE4 ---VRTLSRCRWKKFFCFV
...::. :::. :::
CCDS15 PDKMKNLSKSWWKKYCCFV
240 250
>>CCDS221.1 CDC42 gene_id:998|Hs108|chr1 (191 aa)
initn: 695 init1: 555 opt: 697 Z-score: 660.9 bits: 129.3 E(32554): 1.7e-30
Smith-Waterman score: 697; 57.4% identity (81.8% similar) in 176 aa overlap (32-207:4-178)
10 20 30 40 50 60
pF1KE4 PPRELSEAEPPPLRAPTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYR
::::.::::::::. :..::: : .:..:
CCDS22 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYV
10 20 30
70 80 90 100 110 120
pF1KE4 PTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNI
::..:...: :.. : : . :.:::::::.:::: : ::.:::::.:::::.::::.:.
CCDS22 PTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE4 TEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRAC
:::.::: : :..: :::::: ::::: ... .: .. .. :. :. ::. ..:
CCDS22 KEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKN-KQKPITPETAEKLARDLKAV
100 110 120 130 140 150
190 200 210 220 230
pF1KE4 CYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV
:.::::::::.::.::: :::.:.:
CCDS22 KYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
160 170 180 190
>>CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 (192 aa)
initn: 698 init1: 570 opt: 696 Z-score: 660.0 bits: 129.2 E(32554): 1.9e-30
Smith-Waterman score: 696; 57.3% identity (82.5% similar) in 171 aa overlap (32-202:4-173)
10 20 30 40 50 60
pF1KE4 PPRELSEAEPPPLRAPTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYR
::::.::::::::. :..::: :..:..:
CCDS53 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYI
10 20 30
70 80 90 100 110 120
pF1KE4 PTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNI
::..:..:..:.::: :: . :::::::::.:::: : ::.::::: :::.:.:.::.:.
CCDS53 PTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE4 TEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRAC
:: ::.: : :..:..::::. ::::: ... .: . . :. ::. ..:..: :
CCDS53 RAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEK-KLTPITYPQGLAMAKEIGAV
100 110 120 130 140 150
190 200 210 220 230
pF1KE4 CYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV
:::::::::..:: ::: ::
CCDS53 KYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
160 170 180 190
>>CCDS222.1 CDC42 gene_id:998|Hs108|chr1 (191 aa)
initn: 692 init1: 555 opt: 695 Z-score: 659.1 bits: 129.0 E(32554): 2.2e-30
Smith-Waterman score: 695; 54.9% identity (79.3% similar) in 184 aa overlap (32-215:4-186)
10 20 30 40 50 60
pF1KE4 PPRELSEAEPPPLRAPTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYR
::::.::::::::. :..::: : .:..:
CCDS22 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYV
10 20 30
70 80 90 100 110 120
pF1KE4 PTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNI
::..:...: :.. : : . :.:::::::.:::: : ::.:::::.:::::.::::.:.
CCDS22 PTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE4 TEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRAC
:::.::: : :..: :::::: ::::: ... .: .. .. :. :. ::. ..:
CCDS22 KEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKN-KQKPITPETAEKLARDLKAV
100 110 120 130 140 150
190 200 210 220 230
pF1KE4 CYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV
:.:::::::..::.::: :::.:.: :.
CCDS22 KYVECSALTQRGLKNVFDEAILAALEPPETQPKRKCCIF
160 170 180 190
>>CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 (192 aa)
initn: 695 init1: 572 opt: 695 Z-score: 659.0 bits: 129.0 E(32554): 2.2e-30
Smith-Waterman score: 695; 57.3% identity (83.0% similar) in 171 aa overlap (32-202:4-173)
10 20 30 40 50 60
pF1KE4 PPRELSEAEPPPLRAPTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYR
::::.::::::::. :..::: :..:..:
CCDS11 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYI
10 20 30
70 80 90 100 110 120
pF1KE4 PTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNI
::..:..:..:.::: :: . :::::::::.:::: : ::.::::: :::.:.:.::.:.
CCDS11 PTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE4 TEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRAC
:: ::.: : :..:.:::::. ::::: ... .: . . .:. ::. ..:..: .
CCDS11 RAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERL-RDKKLAPITYPQGLAMAREIGSV
100 110 120 130 140 150
190 200 210 220 230
pF1KE4 CYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV
:::::::::..:: ::: ::
CCDS11 KYLECSALTQRGLKTVFDEAIRAVLCPPPVKKPGKKCTVF
160 170 180 190
>>CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 (205 aa)
initn: 667 init1: 509 opt: 695 Z-score: 658.7 bits: 129.0 E(32554): 2.3e-30
Smith-Waterman score: 695; 52.7% identity (75.1% similar) in 201 aa overlap (27-227:5-198)
10 20 30 40 50 60
pF1KE4 MPPRELSEAEPPPLRAPTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARY
: : .:::.::::::::. :..::. ...: .:
CCDS33 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEY
10 20 30
70 80 90 100 110 120
pF1KE4 RPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQN
::..: ..:.: : : . :.:::::::.:::: : :: ::::: :::::.:.::::
CCDS33 VPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQN
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE4 ITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRA
. :.:.::.. . :..: ::.::: ::::: ..: .:.. .: :. :.: ::..: :
CCDS33 VKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDM-KEKPICVEQGQKLAKEIGA
100 110 120 130 140 150
190 200 210 220 230
pF1KE4 CCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV
:::.::::::::.:: ::: ::.. . : . :: : :::
CCDS33 CCYVECSALTQKGLKTVFDEAIIAILTPKKHTVKK------RIGSRCINCCLIT
160 170 180 190 200
>>CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 (192 aa)
initn: 687 init1: 560 opt: 690 Z-score: 654.4 bits: 128.1 E(32554): 4e-30
Smith-Waterman score: 690; 53.0% identity (82.2% similar) in 185 aa overlap (32-215:4-187)
10 20 30 40 50 60
pF1KE4 PPRELSEAEPPPLRAPTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYR
::::.::::::::. :..::: :..:..:
CCDS13 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYI
10 20 30
70 80 90 100 110 120
pF1KE4 PTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNI
::..:..:..:.::. :: . :::::::::.:::: : ::.::::: :::.:.:.:..:.
CCDS13 PTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE4 TEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRAC
::.::.: : :..:..::::. ::::: ... .: . . .:. ::. .::..: .
CCDS13 RAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEK-KLAPITYPQGLALAKEIDSV
100 110 120 130 140 150
190 200 210 220 230
pF1KE4 CYLECSALTQKNLKEVFDSAILSAI-EHKARLEKKLNAKGVRTLSRCRWKKFFCFV
:::::::::..:: ::: :: ... . .: .:.
CCDS13 KYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRACSLL
160 170 180 190
>>CCDS7748.1 RHOG gene_id:391|Hs108|chr11 (191 aa)
initn: 610 init1: 522 opt: 627 Z-score: 595.9 bits: 117.3 E(32554): 7.1e-27
Smith-Waterman score: 627; 52.0% identity (80.1% similar) in 171 aa overlap (32-202:4-173)
10 20 30 40 50 60
pF1KE4 PPRELSEAEPPPLRAPTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYR
::::.::::::::. :.. :: :..: .:
CCDS77 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYI
10 20 30
70 80 90 100 110 120
pF1KE4 PTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNI
::..:..:.: ::: : ..::::::::..::::.: ::.:.::. :::...: :..:.
CCDS77 PTVFDNYSAQSAVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE4 TEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRAC
.:: ::. : :..:.:::::. ::: . ..: .: . : ..:. :.:.::..:.:
CCDS77 RHKWHPEVCHHCPDVPILLVGTKKDLRAQPDTLRRLKEQG-QAPITPQQGQALAKQIHAV
100 110 120 130 140 150
190 200 210 220 230
pF1KE4 CYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV
::::::: : ..:::: :.
CCDS77 RYLECSALQQDGVKEVFAEAVRAVLNPTPIKRGRSCILL
160 170 180 190
>>CCDS9757.1 RHOJ gene_id:57381|Hs108|chr14 (214 aa)
initn: 609 init1: 478 opt: 618 Z-score: 586.9 bits: 115.8 E(32554): 2.3e-26
Smith-Waterman score: 618; 51.1% identity (76.1% similar) in 184 aa overlap (32-215:22-203)
10 20 30 40 50 60
pF1KE4 PPRELSEAEPPPLRAPTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYR
.:::.::::::::. :..::. ...: .:
CCDS97 MNCKEGTDSSCGCRGNDEKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYV
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 PTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNI
::..: ..: : : : . :.:::::::...:: : ::.::::: :::::.:.:..:.
CCDS97 PTVFDHYAVTVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 TEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRAC
:.:.::.. :..: .:.::: ::::: ..: .: .: :. .. ::. : :
CCDS97 QEEWVPELKDCMPHVPYVLIGTQIDLRDDPKTLARLLYM-KEKPLTYEHGVKLAKAIGAQ
120 130 140 150 160 170
190 200 210 220 230
pF1KE4 CYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV
:::::::::::.:: ::: :::. : : . .:.
CCDS97 CYLECSALTQKGLKAVFDEAILT-IFHPKKKKKRCSEGHSCCSII
180 190 200 210
236 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:19:17 2016 done: Sun Nov 6 04:19:18 2016
Total Scan time: 2.700 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]