Result of FASTA (ccds) for
pFN21AE4023
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4023, 211 aa
1>>>pF1KE4023 211 - 211 aa - 211 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9784+/-0.000719; mu= 15.6155+/- 0.044
mean_var=71.9276+/-14.598, 0's: 0 Z-trim(111.0): 172 B-trim: 334 in 1/50
Lambda= 0.151226
statistics sampled from 11815 (12016) to 11815 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.753), E-opt: 0.2 (0.369), width: 16
Scan time: 2.230
The best scores are: opt bits E(32554)
CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 ( 211) 1398 313.5 6.1e-86
CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 ( 210) 756 173.4 8.9e-44
CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 ( 192) 650 150.3 7.7e-37
CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 ( 192) 645 149.2 1.6e-36
CCDS2795.1 RHOA gene_id:387|Hs108|chr3 ( 193) 645 149.2 1.6e-36
CCDS854.1 RHOC gene_id:389|Hs108|chr1 ( 193) 644 149.0 1.9e-36
CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 ( 192) 612 142.0 2.4e-34
CCDS1699.1 RHOB gene_id:388|Hs108|chr2 ( 196) 604 140.2 8.2e-34
CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 ( 205) 601 139.6 1.3e-33
CCDS7748.1 RHOG gene_id:391|Hs108|chr11 ( 191) 595 138.3 3.1e-33
CCDS222.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 584 135.9 1.6e-32
CCDS9757.1 RHOJ gene_id:57381|Hs108|chr14 ( 214) 584 135.9 1.8e-32
CCDS221.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 581 135.2 2.6e-32
CCDS2190.1 RND3 gene_id:390|Hs108|chr2 ( 244) 568 132.5 2.2e-31
CCDS11452.1 RND2 gene_id:8153|Hs108|chr17 ( 227) 545 127.4 6.8e-30
CCDS82775.1 RHOA gene_id:387|Hs108|chr3 ( 187) 532 124.5 4.2e-29
CCDS1575.1 RHOU gene_id:58480|Hs108|chr1 ( 258) 522 122.5 2.4e-28
CCDS8771.1 RND1 gene_id:27289|Hs108|chr12 ( 232) 501 117.8 5.4e-27
CCDS10068.1 RHOV gene_id:171177|Hs108|chr15 ( 236) 473 111.7 3.8e-25
CCDS3458.1 RHOH gene_id:399|Hs108|chr4 ( 191) 391 93.8 7.8e-20
CCDS5349.1 RAC1 gene_id:5879|Hs108|chr7 ( 211) 355 85.9 1.9e-17
CCDS73330.1 RHOD gene_id:29984|Hs108|chr11 ( 144) 343 83.2 9e-17
CCDS41846.1 RAB35 gene_id:11021|Hs108|chr12 ( 201) 272 67.8 5.3e-12
CCDS11703.1 RAB37 gene_id:326624|Hs108|chr17 ( 216) 271 67.6 6.5e-12
CCDS3170.1 RAP2B gene_id:5912|Hs108|chr3 ( 183) 259 64.9 3.5e-11
CCDS1123.1 RIT1 gene_id:6016|Hs108|chr1 ( 219) 255 64.1 7.4e-11
CCDS58037.1 RIT1 gene_id:6016|Hs108|chr1 ( 236) 255 64.2 7.8e-11
CCDS9271.1 RAN gene_id:5901|Hs108|chr12 ( 216) 254 63.9 8.5e-11
CCDS11921.1 RIT2 gene_id:6014|Hs108|chr18 ( 217) 254 63.9 8.5e-11
>>CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 (211 aa)
initn: 1398 init1: 1398 opt: 1398 Z-score: 1656.3 bits: 313.5 E(32554): 6.1e-86
Smith-Waterman score: 1398; 100.0% identity (100.0% similar) in 211 aa overlap (1-211:1-211)
10 20 30 40 50 60
pF1KE4 MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN
130 140 150 160 170 180
190 200 210
pF1KE4 VEDVFREAAKVALSALKKAQRQKKRRLCLLL
:::::::::::::::::::::::::::::::
CCDS92 VEDVFREAAKVALSALKKAQRQKKRRLCLLL
190 200 210
>>CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 (210 aa)
initn: 749 init1: 749 opt: 756 Z-score: 899.4 bits: 173.4 E(32554): 8.9e-44
Smith-Waterman score: 756; 50.7% identity (79.1% similar) in 211 aa overlap (1-210:1-209)
10 20 30 40 50 60
pF1KE4 MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV
: : : : :: :: . .:.:.::::::::::::::...:.::: :.:.:::.: ...
CCDS81 MTAAQA-AGEEAP-PGVRSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNL
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF
: .: : :...:::::.:::::::: : .. ..:.:.:: .:.:.::.. .:.:::.::
CCDS81 QVKGKPVHLHIWDTAGQDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVNHF
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN
:. .:....:::::::::: . ::: :::.:: .: ... :. ::::::....:
CCDS81 CKKVPIIVVGCKTDLRKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLHDN
120 130 140 150 160 170
190 200 210
pF1KE4 VEDVFREAAKVALSALKKA-QRQKKRRLCLLL
:. ::.:::.::::. . :. . .:..
CCDS81 VHAVFQEAAEVALSSRGRNFWRRITQGFCVVT
180 190 200 210
>>CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 (192 aa)
initn: 658 init1: 615 opt: 650 Z-score: 774.9 bits: 150.3 E(32554): 7.7e-37
Smith-Waterman score: 650; 50.5% identity (76.3% similar) in 194 aa overlap (18-211:2-192)
10 20 30 40 50 60
pF1KE4 MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV
. .: :.::::. ::: ::. :. ..:: .: :.::..:.:.:
CCDS13 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANV
10 20 30 40
70 80 90 100 110 120
pF1KE4 TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF
: :: :.:.:.:::::::::::::::: .: . :::.....:.::.:: :::::: :
CCDS13 MVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHH
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN
: . :..:.: : ::: ::. ..::. .: :::: :::. ..: .. :::::: ...
CCDS13 CPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRG
110 120 130 140 150 160
190 200 210
pF1KE4 VEDVFREAAKVALSALKKAQRQKKRRLCLLL
.. :: :: ...: . ::.:: : ::
CCDS13 LKTVFDEAIRAVLCP--QPTRQQKRA-CSLL
170 180 190
>>CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 (192 aa)
initn: 661 init1: 606 opt: 645 Z-score: 769.0 bits: 149.2 E(32554): 1.6e-36
Smith-Waterman score: 645; 49.0% identity (76.3% similar) in 194 aa overlap (18-211:2-192)
10 20 30 40 50 60
pF1KE4 MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV
. .: :.::::. ::: ::. :. ..:: .: :.::..:.:.:
CCDS53 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANV
10 20 30 40
70 80 90 100 110 120
pF1KE4 TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF
: .: :.:.:.:::::::::::::::: .: . :::.....:.:..:: ::.::: :
CCDS53 MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHH
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN
: . :..:.: : ::: ::. ..::. .: :::: :::. ..: :. :::::: ...
CCDS53 CPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRG
110 120 130 140 150 160
190 200 210
pF1KE4 VEDVFREAAKVALSALKKAQRQKKRRLCLLL
.. :: :: ...: .:..: ::::
CCDS53 LKTVFDEAIRAVLCP---PPVKKRKRKCLLL
170 180 190
>>CCDS2795.1 RHOA gene_id:387|Hs108|chr3 (193 aa)
initn: 687 init1: 615 opt: 645 Z-score: 769.0 bits: 149.2 E(32554): 1.6e-36
Smith-Waterman score: 645; 49.2% identity (77.5% similar) in 191 aa overlap (21-211:7-193)
10 20 30 40 50 60
pF1KE4 MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV
:.::::::.:::: ::.:.:. .::: :.:.:::.:.:..
CCDS27 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADI
10 20 30 40
70 80 90 100 110 120
pF1KE4 TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF
: .:.: : :.:::::::::::::::: .: ..:.:... .: : .:. :: ::: ::
CCDS27 EVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHF
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN
: ..:..:.: : :::.:.. :.: . ::. .: . ..: : :.::::: ...
CCDS27 CPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDG
110 120 130 140 150 160
190 200 210
pF1KE4 VEDVFREAAKVALSALKKAQRQKKRRLCLLL
:..::. :...:: .:.: ::. ::.:
CCDS27 VREVFEMATRAAL----QARRGKKKSGCLVL
170 180 190
>>CCDS854.1 RHOC gene_id:389|Hs108|chr1 (193 aa)
initn: 648 init1: 624 opt: 644 Z-score: 767.8 bits: 149.0 E(32554): 1.9e-36
Smith-Waterman score: 644; 48.7% identity (77.5% similar) in 191 aa overlap (21-211:7-193)
10 20 30 40 50 60
pF1KE4 MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV
:.::::::.:::: ::.:.:. .::: :.:.:::.: :..
CCDS85 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADI
10 20 30 40
70 80 90 100 110 120
pF1KE4 TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF
: .:.: : :.:::::::::::::::: .: ..:.:... .: : .:. :: ::: ::
CCDS85 EVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHF
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN
: ..:..:.: : :::.:.. :.: . ::. .: . ..: : ::::::: .:.
CCDS85 CPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEG
110 120 130 140 150 160
190 200 210
pF1KE4 VEDVFREAAKVALSALKKAQRQKKRRLCLLL
:..::. :....: .....:.:: : .:
CCDS85 VREVFEMATRAGL----QVRKNKRRRGCPIL
170 180 190
>>CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 (192 aa)
initn: 612 init1: 612 opt: 612 Z-score: 730.1 bits: 142.0 E(32554): 2.4e-34
Smith-Waterman score: 612; 50.0% identity (78.4% similar) in 176 aa overlap (18-193:2-177)
10 20 30 40 50 60
pF1KE4 MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV
. .: :.::::. ::: ::. :. ..:: .: :.::..:.:.:
CCDS11 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANV
10 20 30 40
70 80 90 100 110 120
pF1KE4 TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF
: .: :.:.:.:::::::::::::::: .: . :::.....:.:..:: ::.::: :
CCDS11 MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHH
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN
: :..:.: : ::: ::. ...:: .: :::: :::. ..: .. :::::: ...
CCDS11 CPHTPILLVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRG
110 120 130 140 150 160
190 200 210
pF1KE4 VEDVFREAAKVALSALKKAQRQKKRRLCLLL
.. :: :: ...:
CCDS11 LKTVFDEAIRAVLCPPPVKKPGKKCTVF
170 180 190
>>CCDS1699.1 RHOB gene_id:388|Hs108|chr2 (196 aa)
initn: 604 init1: 604 opt: 604 Z-score: 720.6 bits: 140.2 E(32554): 8.2e-34
Smith-Waterman score: 604; 50.3% identity (78.0% similar) in 173 aa overlap (21-193:7-179)
10 20 30 40 50 60
pF1KE4 MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV
:.:.::::.:::: ::.:.:. ::: :.:.:::.:.:..
CCDS16 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADI
10 20 30 40
70 80 90 100 110 120
pF1KE4 TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF
: .:.: : :.:::::::::::::::: .: ..:.:..: .: : .:. :: ::: ::
CCDS16 EVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHF
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN
: ..:..:.. : :::.:.. .: . ::. .: . .:.: ::::::: .:.
CCDS16 CPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEG
110 120 130 140 150 160
190 200 210
pF1KE4 VEDVFREAAKVALSALKKAQRQKKRRLCLLL
:..::. :...::
CCDS16 VREVFETATRAALQKRYGSQNGCINCCKVL
170 180 190
>>CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 (205 aa)
initn: 587 init1: 587 opt: 601 Z-score: 716.8 bits: 139.6 E(32554): 1.3e-33
Smith-Waterman score: 601; 46.5% identity (72.7% similar) in 198 aa overlap (12-209:2-199)
10 20 30 40 50 60
pF1KE4 MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV
: ::: :: :.::::. ::: ::: :.. .:::.:.:.::..:..::
CCDS33 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSV
10 20 30 40 50
70 80 90 100 110 120
pF1KE4 TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF
:::.:. :.:::::::::::::::::: : . :::..:.::.:..:: .: ::. ..
CCDS33 TVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE4 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN
..:..::: . ::: : . : .: . .:: :: . ..: : :.:::: ...
CCDS33 APNVPFLLIGTQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKG
120 130 140 150 160 170
190 200 210
pF1KE4 VEDVFREAAKVALSALKKAQRQKKRRLCLLL
.. :: :: . :. :.. ... :.
CCDS33 LKTVFDEAIIAILTPKKHTVKKRIGSRCINCCLIT
180 190 200
>>CCDS7748.1 RHOG gene_id:391|Hs108|chr11 (191 aa)
initn: 620 init1: 568 opt: 595 Z-score: 710.1 bits: 138.3 E(32554): 3.1e-33
Smith-Waterman score: 595; 45.9% identity (74.2% similar) in 194 aa overlap (18-211:2-191)
10 20 30 40 50 60
pF1KE4 MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV
. .: :.::::. ::: ::. :. ..::..: :.::..:.:.
CCDS77 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQS
10 20 30 40
70 80 90 100 110 120
pF1KE4 TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF
.: .. :.:::.::::::.::::: ::: .:.. .::... .: ::.:: :: ::: :
CCDS77 AVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHH
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE4 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN
: .:..:.: : ::: . . ::.:. ::: .:: . .::.:. :::::: ...
CCDS77 CPDVPILLVGTKKDLRAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDG
110 120 130 140 150 160
190 200 210
pF1KE4 VEDVFREAAKVALSALKKAQRQKKRRLCLLL
:..:: ::....:. :. : :.::
CCDS77 VKEVFAEAVRAVLNPTPI----KRGRSCILL
170 180 190
211 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:20:41 2016 done: Sun Nov 6 04:20:41 2016
Total Scan time: 2.230 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]