Result of FASTA (ccds) for
pFN21AE4019
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4019, 201 aa
1>>>pF1KE4019 201 - 201 aa - 201 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4158+/-0.00103; mu= 12.7371+/- 0.062
mean_var=58.2559+/-11.409, 0's: 0 Z-trim(102.2): 26 B-trim: 7 in 1/50
Lambda= 0.168037
statistics sampled from 6809 (6827) to 6809 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.576), E-opt: 0.2 (0.21), width: 16
Scan time: 1.680
The best scores are: opt bits E(32554)
CCDS9250.1 TMED2 gene_id:10959|Hs108|chr12 ( 201) 1291 321.3 2.5e-88
CCDS4120.1 TMED7 gene_id:51014|Hs108|chr5 ( 224) 407 107.0 8.9e-24
CCDS10310.1 TMED3 gene_id:23423|Hs108|chr15 ( 217) 350 93.2 1.3e-19
CCDS54887.1 TICAM2 gene_id:100302736|Hs108|chr5 ( 404) 323 86.7 2.1e-17
CCDS54888.1 TICAM2 gene_id:100302736|Hs108|chr5 ( 188) 309 83.2 1.1e-16
CCDS4428.1 TMED9 gene_id:54732|Hs108|chr5 ( 235) 272 74.3 6.6e-14
CCDS5493.1 TMED4 gene_id:222068|Hs108|chr7 ( 227) 253 69.7 1.6e-12
CCDS73768.1 TMED3 gene_id:23423|Hs108|chr15 ( 155) 242 67.0 7e-12
CCDS81914.1 TMED3 gene_id:23423|Hs108|chr15 ( 173) 242 67.0 7.7e-12
CCDS9840.1 TMED10 gene_id:10972|Hs108|chr14 ( 219) 232 64.6 5.2e-11
>>CCDS9250.1 TMED2 gene_id:10959|Hs108|chr12 (201 aa)
initn: 1291 init1: 1291 opt: 1291 Z-score: 1699.3 bits: 321.3 E(32554): 2.5e-88
Smith-Waterman score: 1291; 100.0% identity (100.0% similar) in 201 aa overlap (1-201:1-201)
10 20 30 40 50 60
pF1KE4 MVTLAELLVLLAALLATVSGYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 MVTLAELLVLLAALLATVSGYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 ITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 ITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 METEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 METEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVL
130 140 150 160 170 180
190 200
pF1KE4 VAMTLGQIYYLKRFFEVRRVV
:::::::::::::::::::::
CCDS92 VAMTLGQIYYLKRFFEVRRVV
190 200
>>CCDS4120.1 TMED7 gene_id:51014|Hs108|chr5 (224 aa)
initn: 400 init1: 279 opt: 407 Z-score: 540.3 bits: 107.0 E(32554): 8.9e-24
Smith-Waterman score: 407; 35.2% identity (65.8% similar) in 193 aa overlap (8-199:24-216)
10 20 30 40
pF1KE4 MVTLAELLVLLAALLATVSGYFVSIDAHAEECFFERVTSGTKMG
:.::. . .: . .:..::.: ...:::
CCDS41 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCT
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 LIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPK
: :.: :: :.: .. ::.: .:: ... ..::.: .:::::::::..::.: :
CCDS41 LEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 IVMFTIDIGEAPKGQDMETEAHQ-NKLEEMINELAVAMTAVKHEQEYMEVRERIHRAIND
:.: ...:: : :... ...: . :. .: : ....:: :. .
CCDS41 TVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAE
130 140 150 160 170 180
170 180 190 200
pF1KE4 NTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV
. :.::. :: :::.:.....::.. :: :: .:
CCDS41 DLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTTRVGS
190 200 210 220
>>CCDS10310.1 TMED3 gene_id:23423|Hs108|chr15 (217 aa)
initn: 330 init1: 233 opt: 350 Z-score: 465.9 bits: 93.2 E(32554): 1.3e-19
Smith-Waterman score: 350; 32.4% identity (66.5% similar) in 176 aa overlap (28-201:36-211)
10 20 30 40 50
pF1KE4 MVTLAELLVLLAALLATVSGYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDI
.:..:: :.: .:.:..: ..: :: :.
CCDS10 PRSASVLLLLLLLRRAEQPCGAELTFELPDNAKQCFHEEVEQGVKFSLDYQVITGGHYDV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 DVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIG-EAP
: . :... ::. ... ..:. :.. :.:.:::::..::.. : :.: ...: : :
CCDS10 DCYVEDPQGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFSHKTVYFDFQVGDEPP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 KGQDMETEAHQ-NKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFF
:: ... ...: . :. .: : ....:: :: .. :::: ::
CCDS10 ILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVG
130 140 150 160 170 180
180 190 200
pF1KE4 EALVLVAMTLGQIYYLKRFFEVRRVV
:...: .....:. :: :: .: .
CCDS10 ETIALFVVSFSQVLLLKSFFTEKRPISRAVHS
190 200 210
>>CCDS54887.1 TICAM2 gene_id:100302736|Hs108|chr5 (404 aa)
initn: 279 init1: 279 opt: 323 Z-score: 426.1 bits: 86.7 E(32554): 2.1e-17
Smith-Waterman score: 323; 33.7% identity (63.9% similar) in 166 aa overlap (8-172:24-189)
10 20 30 40
pF1KE4 MVTLAELLVLLAALLATVSGYFVSIDAHAEECFFERVTSGTKMG
:.::. . .: . .:..::.: ...:::
CCDS54 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCT
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 LIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPK
: :.: :: :.: .. ::.: .:: ... ..::.: .:::::::::..::.: :
CCDS54 LEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 IVMFTIDIGEAPKGQDMETEAHQ-NKLEEMINELAVAMTAVKHEQEYMEVRERIHRAIND
:.: ...:: : :... ...: . :. .: : ....:: :. .
CCDS54 TVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAE
130 140 150 160 170 180
170 180 190 200
pF1KE4 NTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV
. :.::. :
CCDS54 DLNTRVAYWHSVDTSPGYHESDSKKSEDLSLCNVAEHSNTTEGPTGKQEGAQSVEEMFEE
190 200 210 220 230 240
>>CCDS54888.1 TICAM2 gene_id:100302736|Hs108|chr5 (188 aa)
initn: 307 init1: 279 opt: 309 Z-score: 413.2 bits: 83.2 E(32554): 1.1e-16
Smith-Waterman score: 309; 33.7% identity (63.8% similar) in 163 aa overlap (8-169:24-186)
10 20 30 40
pF1KE4 MVTLAELLVLLAALLATVSGYFVSIDAHAEECFFERVTSGTKMG
:.::. . .: . .:..::.: ...:::
CCDS54 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCT
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE4 LIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPK
: :.: :: :.: .. ::.: .:: ... ..::.: .:::::::::..::.: :
CCDS54 LEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE4 IVMFTIDIGEAPKGQDMETEAHQ-NKLEEMINELAVAMTAVKHEQEYMEVRERIHRAIND
:.: ...:: : :... ...: . :. .: : ....:: :. .
CCDS54 TVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAE
130 140 150 160 170 180
170 180 190 200
pF1KE4 NTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV
. :.::
CCDS54 DLNTRVAY
>>CCDS4428.1 TMED9 gene_id:54732|Hs108|chr5 (235 aa)
initn: 175 init1: 157 opt: 272 Z-score: 363.1 bits: 74.3 E(32554): 6.6e-14
Smith-Waterman score: 281; 28.3% identity (61.8% similar) in 212 aa overlap (9-201:25-235)
10 20 30 40
pF1KE4 MVTLAELLVLLAALLATV-SGYFVSIDAHAEECFFERVTSGT--
.::. ::: :. . : ..::.:.. . :
CCDS44 MAVELGVLLVRPRPGTGLGRVMRTLLLVLWLATRGSALYFHIGETEKKCFIEEIPDETMV
10 20 30 40 50 60
50 60 70 80 90
pF1KE4 ----------KMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYK
:. .. : : : . ::. :..: : . : :..::..: : ..
CCDS44 IGNYRTQLYDKQREEYQPATPG-LGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQ
70 80 90 100 110
100 110 120 130 140
pF1KE4 FCF---SNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEM---INELAVAMTAVK
.:. :...: .. .. .:: . ...:. : ..:: :. . .:. . ..
CCDS44 ICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQ
120 130 140 150 160 170
150 160 170 180 190 200
pF1KE4 HEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV
.::.:.. ::. : ...::.::. ::....:.:::. . :. .:: :::....:
CCDS44 KEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKLV
180 190 200 210 220 230
>>CCDS5493.1 TMED4 gene_id:222068|Hs108|chr7 (227 aa)
initn: 283 init1: 142 opt: 253 Z-score: 338.5 bits: 69.7 E(32554): 1.6e-12
Smith-Waterman score: 276; 27.4% identity (59.9% similar) in 212 aa overlap (9-201:17-227)
10 20 30 40
pF1KE4 MVTLAELLVLLAALLAT-VSGYFVSIDAHAEECFFERVTSGT----------
.:: :: :: ..: . : ..::.:.. . :
CCDS54 MAGVGAGPLRAMGRQALLLLALCATGAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQM
10 20 30 40 50 60
50 60 70 80 90
pF1KE4 --KMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCF---SN
:. .: . : : . ::. ::.: . . . : :..::..: : ...:. :.
CCDS54 WDKQKEVFLPSTPG-LGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNST
70 80 90 100 110
100 110 120 130 140 150
pF1KE4 RMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEM---INELAVAMTAVKHEQEYMEV
::. .. . .:: . ..... : ..:: :. .: . ...::.:..
CCDS54 RMALFAGGKLRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRY
120 130 140 150 160 170
160 170 180 190 200
pF1KE4 RERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV
::. : ...::.::. ::. ....:. . :. .:: :::....:
CCDS54 REERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV
180 190 200 210 220
>>CCDS73768.1 TMED3 gene_id:23423|Hs108|chr15 (155 aa)
initn: 233 init1: 233 opt: 242 Z-score: 326.8 bits: 67.0 E(32554): 7e-12
Smith-Waterman score: 242; 36.0% identity (75.3% similar) in 89 aa overlap (28-116:36-124)
10 20 30 40 50
pF1KE4 MVTLAELLVLLAALLATVSGYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDI
.:..:: :.: .:.:..: ..: :: :.
CCDS73 PRSASVLLLLLLLRRAEQPCGAELTFELPDNAKQCFHEEVEQGVKFSLDYQVITGGHYDV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 DVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPK
: . :... ::. ... ..:. :.. :.:.:::::..::.. : :.: ...:. :
CCDS73 DCYVEDPQGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFSHKTVYFDFQVGDEPP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 GQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEA
CCDS73 ILPDMGNRVTALTQGPSASPTPTPPLRVPV
130 140 150
>>CCDS81914.1 TMED3 gene_id:23423|Hs108|chr15 (173 aa)
initn: 233 init1: 233 opt: 242 Z-score: 326.0 bits: 67.0 E(32554): 7.7e-12
Smith-Waterman score: 242; 36.0% identity (75.3% similar) in 89 aa overlap (28-116:36-124)
10 20 30 40 50
pF1KE4 MVTLAELLVLLAALLATVSGYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDI
.:..:: :.: .:.:..: ..: :: :.
CCDS81 PRSASVLLLLLLLRRAEQPCGAELTFELPDNAKQCFHEEVEQGVKFSLDYQVITGGHYDV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE4 DVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPK
: . :... ::. ... ..:. :.. :.:.:::::..::.. : :.: ...:. :
CCDS81 DCYVEDPQGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFSHKTVYFDFQVGDEPP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE4 GQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEA
CCDS81 ILPDMGNRVTALTQRFRGAYWKEVDKMVDYMQPGGTPATEGLGRLAPS
130 140 150 160 170
>>CCDS9840.1 TMED10 gene_id:10972|Hs108|chr14 (219 aa)
initn: 195 init1: 153 opt: 232 Z-score: 311.2 bits: 64.6 E(32554): 5.2e-11
Smith-Waterman score: 232; 22.9% identity (61.2% similar) in 201 aa overlap (7-201:20-218)
10 20 30 40
pF1KE4 MVTLAELLVLLAALLATVSGYFVSIDAHAEECFFERVTSGTKMGLIF
:: ::. :. . .. . :... .:. :.. . . .
CCDS98 MSGLSGPPARRGPFPLALLLLFLLGPRLVLAISFHLPINSR--KCLREEIHKDLLVTGAY
10 20 30 40 50
50 60 70 80 90 100
pF1KE4 EVAE--GGFLDIDVEITGPDNKG--IYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTP
:... :: . .. :. : .:. . ..::..:... .. :: .. . :
CCDS98 EISDQSGGAGGLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE4 -KIVMFTIDIG-EAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAI
..:.. . : :: . ... . . :: . .: .. .. ::. ::. :
CCDS98 DQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDT
120 130 140 150 160 170
170 180 190 200
pF1KE4 NDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV
:..::.::. .:.: . :.... :..::.:::......
CCDS98 NESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE
180 190 200 210
201 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:21:51 2016 done: Sun Nov 6 04:21:52 2016
Total Scan time: 1.680 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]