Result of FASTA (omim) for
pFN21AE3993
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3993, 274 aa
1>>>pF1KE3993 274 - 274 aa - 274 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8033+/-0.000519; mu= 12.1114+/- 0.031
mean_var=195.5813+/-41.677, 0's: 0 Z-trim(112.0): 639 B-trim: 879 in 1/52
Lambda= 0.091709
statistics sampled from 19943 (20783) to 19943 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.61), E-opt: 0.2 (0.244), width: 16
Scan time: 6.200
The best scores are: opt bits E(85289)
NP_078984 (OMIM: 615052) ankyrin repeat and SOCS b ( 274) 1835 255.9 5.8e-68
NP_937886 (OMIM: 615052) ankyrin repeat and SOCS b ( 318) 1823 254.5 1.9e-67
NP_065690 (OMIM: 263650,605706) receptor-interacti ( 784) 377 63.7 1.2e-09
XP_016863601 (OMIM: 106410,600919) PREDICTED: anky (1689) 363 62.4 6.4e-09
XP_016863600 (OMIM: 106410,600919) PREDICTED: anky (1755) 362 62.3 7.2e-09
XP_016863598 (OMIM: 106410,600919) PREDICTED: anky (1770) 362 62.3 7.2e-09
XP_016863594 (OMIM: 106410,600919) PREDICTED: anky (1810) 362 62.3 7.3e-09
XP_016863591 (OMIM: 106410,600919) PREDICTED: anky (1838) 362 62.3 7.4e-09
XP_016863584 (OMIM: 106410,600919) PREDICTED: anky (1871) 362 62.3 7.5e-09
XP_016863569 (OMIM: 106410,600919) PREDICTED: anky (1970) 362 62.4 7.7e-09
XP_016863568 (OMIM: 106410,600919) PREDICTED: anky (2006) 362 62.4 7.7e-09
XP_016863566 (OMIM: 106410,600919) PREDICTED: anky (4074) 362 62.9 1.1e-08
XP_016863561 (OMIM: 106410,600919) PREDICTED: anky (4137) 362 62.9 1.1e-08
XP_016863558 (OMIM: 106410,600919) PREDICTED: anky (4175) 362 62.9 1.1e-08
XP_016863597 (OMIM: 106410,600919) PREDICTED: anky (1772) 347 60.3 2.9e-08
XP_016863599 (OMIM: 106410,600919) PREDICTED: anky (1763) 346 60.2 3.1e-08
XP_016863596 (OMIM: 106410,600919) PREDICTED: anky (1797) 346 60.2 3.2e-08
XP_016863595 (OMIM: 106410,600919) PREDICTED: anky (1806) 346 60.2 3.2e-08
XP_016863592 (OMIM: 106410,600919) PREDICTED: anky (1816) 346 60.2 3.2e-08
XP_016863593 (OMIM: 106410,600919) PREDICTED: anky (1818) 346 60.2 3.2e-08
XP_016863590 (OMIM: 106410,600919) PREDICTED: anky (1839) 346 60.2 3.2e-08
XP_016863589 (OMIM: 106410,600919) PREDICTED: anky (1846) 346 60.2 3.2e-08
XP_016863588 (OMIM: 106410,600919) PREDICTED: anky (1850) 346 60.2 3.2e-08
XP_016863587 (OMIM: 106410,600919) PREDICTED: anky (1851) 346 60.2 3.2e-08
XP_016863586 (OMIM: 106410,600919) PREDICTED: anky (1858) 346 60.2 3.2e-08
XP_016863585 (OMIM: 106410,600919) PREDICTED: anky (1862) 346 60.2 3.2e-08
NP_001120965 (OMIM: 106410,600919) ankyrin-2 isofo (1863) 346 60.2 3.2e-08
XP_016863583 (OMIM: 106410,600919) PREDICTED: anky (1871) 346 60.2 3.2e-08
NP_066187 (OMIM: 106410,600919) ankyrin-2 isoform (1872) 346 60.2 3.2e-08
XP_016863580 (OMIM: 106410,600919) PREDICTED: anky (1879) 346 60.2 3.2e-08
XP_016863582 (OMIM: 106410,600919) PREDICTED: anky (1881) 346 60.2 3.2e-08
XP_016863581 (OMIM: 106410,600919) PREDICTED: anky (1882) 346 60.2 3.2e-08
XP_016863579 (OMIM: 106410,600919) PREDICTED: anky (1886) 346 60.2 3.3e-08
XP_016863578 (OMIM: 106410,600919) PREDICTED: anky (1887) 346 60.2 3.3e-08
XP_016863577 (OMIM: 106410,600919) PREDICTED: anky (1893) 346 60.2 3.3e-08
XP_016863576 (OMIM: 106410,600919) PREDICTED: anky (1898) 346 60.2 3.3e-08
XP_016863575 (OMIM: 106410,600919) PREDICTED: anky (1899) 346 60.2 3.3e-08
XP_016863574 (OMIM: 106410,600919) PREDICTED: anky (1902) 346 60.2 3.3e-08
XP_016863573 (OMIM: 106410,600919) PREDICTED: anky (1915) 346 60.2 3.3e-08
XP_016863572 (OMIM: 106410,600919) PREDICTED: anky (1917) 346 60.2 3.3e-08
XP_016863571 (OMIM: 106410,600919) PREDICTED: anky (1926) 346 60.2 3.3e-08
XP_016863570 (OMIM: 106410,600919) PREDICTED: anky (1931) 346 60.2 3.3e-08
XP_016863567 (OMIM: 106410,600919) PREDICTED: anky (2020) 346 60.3 3.4e-08
XP_011541040 (OMIM: 608774) PREDICTED: ankyrin rep ( 702) 337 58.4 4.4e-08
NP_848605 (OMIM: 608774) ankyrin repeat and protei ( 765) 337 58.4 4.6e-08
XP_011541039 (OMIM: 608774) PREDICTED: ankyrin rep ( 766) 337 58.4 4.6e-08
XP_016872964 (OMIM: 608774) PREDICTED: ankyrin rep ( 775) 337 58.4 4.6e-08
XP_011541038 (OMIM: 608774) PREDICTED: ankyrin rep ( 776) 337 58.4 4.6e-08
NP_001139 (OMIM: 106410,600919) ankyrin-2 isoform (3957) 346 60.7 4.8e-08
XP_005263002 (OMIM: 106410,600919) PREDICTED: anky (4072) 346 60.8 4.9e-08
>>NP_078984 (OMIM: 615052) ankyrin repeat and SOCS box p (274 aa)
initn: 1835 init1: 1835 opt: 1835 Z-score: 1341.2 bits: 255.9 E(85289): 5.8e-68
Smith-Waterman score: 1835; 100.0% identity (100.0% similar) in 274 aa overlap (1-274:1-274)
10 20 30 40 50 60
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 RCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANIDIQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 LHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANIDIQN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 GFLLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 GFLLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADT
190 200 210 220 230 240
250 260 270
pF1KE3 NTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
::::::::::::::::::::::::::::::::::
NP_078 NTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
250 260 270
>>NP_937886 (OMIM: 615052) ankyrin repeat and SOCS box p (318 aa)
initn: 1823 init1: 1823 opt: 1823 Z-score: 1332.0 bits: 254.5 E(85289): 1.9e-67
Smith-Waterman score: 1823; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272)
10 20 30 40 50 60
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 RCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANIDIQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 LHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANIDIQN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 GFLLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 GFLLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADT
190 200 210 220 230 240
250 260 270
pF1KE3 NTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
::::::::::::::::::::::::::::::::
NP_937 NTRNYEGQTPLAVSISISGSSRPCLDFLQEVTRQPRNLQDLCRIKIRQCIGLQNLKLLDE
250 260 270 280 290 300
NP_937 LPIAKVMKDYLKHKFDDI
310
>>NP_065690 (OMIM: 263650,605706) receptor-interacting s (784 aa)
initn: 332 init1: 166 opt: 377 Z-score: 294.3 bits: 63.7 E(85289): 1.2e-09
Smith-Waterman score: 377; 33.3% identity (68.3% similar) in 246 aa overlap (21-261:413-651)
10 20 30 40 50
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTL
:...::. . :.:. . :. : .:
NP_065 SRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLMKILQPQDVDLALDS-GASL
390 400 410 420 430 440
60 70 80 90 100
pF1KE3 LHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRAR-IARLMLESEYRSDI
::... :.:.:.. .: ..:.:.... :. : ::.:. . :.: ...:.: :.
NP_065 LHLAVEAGQEECAKWLLLNNANPNLSNRRGS-TPLHMAVER-RVRGVVELLLA---RKIS
450 460 470 480 490
110 120 130 140 150 160
pF1KE3 INAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKIL
.:::..: :: :: ::. : .: .::::: .: :. .. .: ::...: . . . :.::
NP_065 VNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRIL
500 510 520 530 540 550
170 180 190 200 210 220
pF1KE3 LDHNANIDIQ--NGFL-LRYAVIKSNHSYCRMFL-QRGADTNLGRLEDGQTPLHLSALRD
: .......: ...: :.::. ... ... : :...: : ::.:::::.: :
NP_065 LRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTL-DGRTPLHLAAQRG
560 570 580 590 600 610
230 240 250 260 270
pF1KE3 DVLCARMLYNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
::.: . .:.:. . .:::: :. . .:
NP_065 HYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALH
620 630 640 650 660 670
NP_065 LAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADVIDLFDEQG
680 690 700 710 720 730
>>XP_016863601 (OMIM: 106410,600919) PREDICTED: ankyrin- (1689 aa)
initn: 630 init1: 177 opt: 363 Z-score: 281.1 bits: 62.4 E(85289): 6.4e-09
Smith-Waterman score: 369; 31.6% identity (64.5% similar) in 231 aa overlap (27-254:122-343)
10 20 30 40 50
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAA
. .:. .::.: . . .:.: : .
XP_016 VKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQ
100 110 120 130 140 150
60 70 80 90 100 110
pF1KE3 RGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSND
.:... : ..::. . :. . ::: :: . .. : :.:.... .:. .:..
XP_016 QGHNQAVAILLENDTKGKVR-----LPALHIAARKDDTKSAALLLQNDHNADV---QSKS
160 170 180 190 200
120 130 140 150 160 170
pF1KE3 GWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANI
:.::::.::::: . . :::. : :: . .: :::..: : .. ::.:::....:
XP_016 GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQI
210 220 230 240 250 260
180 190 200 210 220 230
pF1KE3 DIQ--NGFLLRYAVIKSNHSYC-RMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARML
: . .:. . . .:.:. ...:.::: :.: ..: .:::..: : : :.. :
XP_016 DAKTRDGLTPLHCAARSGHDQVVELLLERGAPL-LARTKNGLSPLHMAAQGDHVECVKHL
270 280 290 300 310 320
240 250 260 270
pF1KE3 YNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
.. : .. . . : : :.
XP_016 LQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALRGETALHMAARAGQV
330 340 350 360 370 380
>--
initn: 445 init1: 135 opt: 312 Z-score: 244.6 bits: 55.7 E(85289): 6.9e-07
Smith-Waterman score: 381; 32.7% identity (63.3% similar) in 245 aa overlap (13-254:401-640)
10 20 30 40
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNG
.:. .. : : .. :. .:.. :..
XP_016 TALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDA
380 390 400 410 420 430
50 60 70 80 90 100
pF1KE3 RDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLE
.::.: ::.:: .:. . :.:: :: .. ::: :: :: .: .:.:.:.
XP_016 ATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATK-KGFTPLHVAAKYGSLDVAKLLLQ
440 450 460 470 480
110 120 130 140 150 160
pF1KE3 SEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRER
: .. ...: ::::::::: .. . :::: : . .: :::..: ...
XP_016 ---RRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQ
490 500 510 520 530 540
170 180 190 200 210
pF1KE3 SSCVKILLDHNA--NIDIQNGFL-LRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLH
. .. ::...: :: ..: :. : ... .. ..:..::. ... ..: : ::
XP_016 MQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST-KSGLTSLH
550 560 570 580 590 600
220 230 240 250 260 270
pF1KE3 LSALRDDVLCARMLYNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
:.: .: : : .: ..::: .... : ::: :.
XP_016 LAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKN
610 620 630 640 650 660
XP_016 GYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEV
670 680 690 700 710 720
>>XP_016863600 (OMIM: 106410,600919) PREDICTED: ankyrin- (1755 aa)
initn: 522 init1: 177 opt: 362 Z-score: 280.2 bits: 62.3 E(85289): 7.2e-09
Smith-Waterman score: 369; 31.6% identity (64.5% similar) in 231 aa overlap (27-254:122-343)
10 20 30 40 50
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAA
. .:. .::.: . . .:.: : .
XP_016 VKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQ
100 110 120 130 140 150
60 70 80 90 100 110
pF1KE3 RGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSND
.:... : ..::. . :. . ::: :: . .. : :.:.... .:. .:..
XP_016 QGHNQAVAILLENDTKGKVR-----LPALHIAARKDDTKSAALLLQNDHNADV---QSKS
160 170 180 190 200
120 130 140 150 160 170
pF1KE3 GWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANI
:.::::.::::: . . :::. : :: . .: :::..: : .. ::.:::....:
XP_016 GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQI
210 220 230 240 250 260
180 190 200 210 220 230
pF1KE3 DIQ--NGFLLRYAVIKSNHSYC-RMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARML
: . .:. . . .:.:. ...:.::: :.: ..: .:::..: : : :.. :
XP_016 DAKTRDGLTPLHCAARSGHDQVVELLLERGAPL-LARTKNGLSPLHMAAQGDHVECVKHL
270 280 290 300 310 320
240 250 260 270
pF1KE3 YNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
.. : .. . . : : :.
XP_016 LQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRI
330 340 350 360 370 380
>--
initn: 426 init1: 135 opt: 312 Z-score: 244.4 bits: 55.7 E(85289): 7.1e-07
Smith-Waterman score: 381; 32.7% identity (63.3% similar) in 245 aa overlap (13-254:467-706)
10 20 30 40
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNG
.:. .. : : .. :. .:.. :..
XP_016 TALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDA
440 450 460 470 480 490
50 60 70 80 90 100
pF1KE3 RDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLE
.::.: ::.:: .:. . :.:: :: .. ::: :: :: .: .:.:.:.
XP_016 ATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATK-KGFTPLHVAAKYGSLDVAKLLLQ
500 510 520 530 540 550
110 120 130 140 150 160
pF1KE3 SEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRER
: .. ...: ::::::::: .. . :::: : . .: :::..: ...
XP_016 ---RRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQ
560 570 580 590 600 610
170 180 190 200 210
pF1KE3 SSCVKILLDHNA--NIDIQNGFL-LRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLH
. .. ::...: :: ..: :. : ... .. ..:..::. ... ..: : ::
XP_016 MQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST-KSGLTSLH
620 630 640 650 660 670
220 230 240 250 260 270
pF1KE3 LSALRDDVLCARMLYNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
:.: .: : : .: ..::: .... : ::: :.
XP_016 LAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKN
680 690 700 710 720 730
XP_016 GYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEV
740 750 760 770 780 790
>>XP_016863598 (OMIM: 106410,600919) PREDICTED: ankyrin- (1770 aa)
initn: 522 init1: 177 opt: 362 Z-score: 280.2 bits: 62.3 E(85289): 7.2e-09
Smith-Waterman score: 369; 31.6% identity (64.5% similar) in 231 aa overlap (27-254:122-343)
10 20 30 40 50
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAA
. .:. .::.: . . .:.: : .
XP_016 VKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQ
100 110 120 130 140 150
60 70 80 90 100 110
pF1KE3 RGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSND
.:... : ..::. . :. . ::: :: . .. : :.:.... .:. .:..
XP_016 QGHNQAVAILLENDTKGKVR-----LPALHIAARKDDTKSAALLLQNDHNADV---QSKS
160 170 180 190 200
120 130 140 150 160 170
pF1KE3 GWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANI
:.::::.::::: . . :::. : :: . .: :::..: : .. ::.:::....:
XP_016 GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQI
210 220 230 240 250 260
180 190 200 210 220 230
pF1KE3 DIQ--NGFLLRYAVIKSNHSYC-RMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARML
: . .:. . . .:.:. ...:.::: :.: ..: .:::..: : : :.. :
XP_016 DAKTRDGLTPLHCAARSGHDQVVELLLERGAPL-LARTKNGLSPLHMAAQGDHVECVKHL
270 280 290 300 310 320
240 250 260 270
pF1KE3 YNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
.. : .. . . : : :.
XP_016 LQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRI
330 340 350 360 370 380
>--
initn: 426 init1: 135 opt: 312 Z-score: 244.4 bits: 55.7 E(85289): 7.1e-07
Smith-Waterman score: 381; 32.7% identity (63.3% similar) in 245 aa overlap (13-254:467-706)
10 20 30 40
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNG
.:. .. : : .. :. .:.. :..
XP_016 TALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDA
440 450 460 470 480 490
50 60 70 80 90 100
pF1KE3 RDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLE
.::.: ::.:: .:. . :.:: :: .. ::: :: :: .: .:.:.:.
XP_016 ATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATK-KGFTPLHVAAKYGSLDVAKLLLQ
500 510 520 530 540 550
110 120 130 140 150 160
pF1KE3 SEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRER
: .. ...: ::::::::: .. . :::: : . .: :::..: ...
XP_016 ---RRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQ
560 570 580 590 600 610
170 180 190 200 210
pF1KE3 SSCVKILLDHNA--NIDIQNGFL-LRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLH
. .. ::...: :: ..: :. : ... .. ..:..::. ... ..: : ::
XP_016 MQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST-KSGLTSLH
620 630 640 650 660 670
220 230 240 250 260 270
pF1KE3 LSALRDDVLCARMLYNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
:.: .: : : .: ..::: .... : ::: :.
XP_016 LAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKN
680 690 700 710 720 730
XP_016 GYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEV
740 750 760 770 780 790
>>XP_016863594 (OMIM: 106410,600919) PREDICTED: ankyrin- (1810 aa)
initn: 522 init1: 177 opt: 362 Z-score: 280.1 bits: 62.3 E(85289): 7.3e-09
Smith-Waterman score: 369; 31.6% identity (64.5% similar) in 231 aa overlap (27-254:122-343)
10 20 30 40 50
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAA
. .:. .::.: . . .:.: : .
XP_016 VKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQ
100 110 120 130 140 150
60 70 80 90 100 110
pF1KE3 RGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSND
.:... : ..::. . :. . ::: :: . .. : :.:.... .:. .:..
XP_016 QGHNQAVAILLENDTKGKVR-----LPALHIAARKDDTKSAALLLQNDHNADV---QSKS
160 170 180 190 200
120 130 140 150 160 170
pF1KE3 GWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANI
:.::::.::::: . . :::. : :: . .: :::..: : .. ::.:::....:
XP_016 GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQI
210 220 230 240 250 260
180 190 200 210 220 230
pF1KE3 DIQ--NGFLLRYAVIKSNHSYC-RMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARML
: . .:. . . .:.:. ...:.::: :.: ..: .:::..: : : :.. :
XP_016 DAKTRDGLTPLHCAARSGHDQVVELLLERGAPL-LARTKNGLSPLHMAAQGDHVECVKHL
270 280 290 300 310 320
240 250 260 270
pF1KE3 YNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
.. : .. . . : : :.
XP_016 LQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRI
330 340 350 360 370 380
>--
initn: 426 init1: 135 opt: 312 Z-score: 244.3 bits: 55.7 E(85289): 7.2e-07
Smith-Waterman score: 381; 32.7% identity (63.3% similar) in 245 aa overlap (13-254:467-706)
10 20 30 40
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNG
.:. .. : : .. :. .:.. :..
XP_016 TALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDA
440 450 460 470 480 490
50 60 70 80 90 100
pF1KE3 RDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLE
.::.: ::.:: .:. . :.:: :: .. ::: :: :: .: .:.:.:.
XP_016 ATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATK-KGFTPLHVAAKYGSLDVAKLLLQ
500 510 520 530 540 550
110 120 130 140 150 160
pF1KE3 SEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRER
: .. ...: ::::::::: .. . :::: : . .: :::..: ...
XP_016 ---RRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQ
560 570 580 590 600 610
170 180 190 200 210
pF1KE3 SSCVKILLDHNA--NIDIQNGFL-LRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLH
. .. ::...: :: ..: :. : ... .. ..:..::. ... ..: : ::
XP_016 MQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST-KSGLTSLH
620 630 640 650 660 670
220 230 240 250 260 270
pF1KE3 LSALRDDVLCARMLYNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
:.: .: : : .: ..::: .... : ::: :.
XP_016 LAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKN
680 690 700 710 720 730
XP_016 GYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEV
740 750 760 770 780 790
>>XP_016863591 (OMIM: 106410,600919) PREDICTED: ankyrin- (1838 aa)
initn: 421 init1: 177 opt: 362 Z-score: 280.0 bits: 62.3 E(85289): 7.4e-09
Smith-Waterman score: 385; 32.5% identity (66.7% similar) in 243 aa overlap (15-254:436-673)
10 20 30 40
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRD
: .. :. ::.:..:: .:..: ..:
XP_016 IHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARA
410 420 430 440 450 460
50 60 70 80 90 100
pF1KE3 ANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESE
. : ::... :: . :...:.: : : . .:.: :: .: .:.. .: ..::.
XP_016 REEQTPLHIASRLGKTEIVQLLLQHMAHPDAATT-NGYTPLHISAREGQVDVASVLLEAG
470 480 490 500 510 520
110 120 130 140 150 160
pF1KE3 YRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSS
.. . : :.:::::::.:: . ..:::. .: .: . .: :::..: ... .
XP_016 AAHSLATKK---GFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGYTPLHIAAKKNQMQ
530 540 550 560 570 580
170 180 190 200 210 220
pF1KE3 CVKILLDHNA--NIDIQNGFL-LRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLS
.. ::...: :: ..: :. : ... .. ..:..::. ... ..: : :::.
XP_016 IASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST-KSGLTSLHLA
590 600 610 620 630 640
230 240 250 260 270
pF1KE3 ALRDDVLCARMLYNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
: .: : : .: ..::: .... : ::: :.
XP_016 AQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGY
650 660 670 680 690 700
XP_016 TPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTT
710 720 730 740 750 760
>--
initn: 421 init1: 177 opt: 362 Z-score: 280.0 bits: 62.3 E(85289): 7.4e-09
Smith-Waterman score: 369; 31.6% identity (64.5% similar) in 231 aa overlap (27-254:122-343)
10 20 30 40 50
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAA
. .:. .::.: . . .:.: : .
XP_016 VKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQ
100 110 120 130 140 150
60 70 80 90 100 110
pF1KE3 RGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSND
.:... : ..::. . :. . ::: :: . .. : :.:.... .:. .:..
XP_016 QGHNQAVAILLENDTKGKVR-----LPALHIAARKDDTKSAALLLQNDHNADV---QSKS
160 170 180 190 200
120 130 140 150 160 170
pF1KE3 GWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANI
:.::::.::::: . . :::. : :: . .: :::..: : .. ::.:::....:
XP_016 GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQI
210 220 230 240 250 260
180 190 200 210 220 230
pF1KE3 DIQ--NGFLLRYAVIKSNHSYC-RMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARML
: . .:. . . .:.:. ...:.::: :.: ..: .:::..: : : :.. :
XP_016 DAKTRDGLTPLHCAARSGHDQVVELLLERGAPL-LARTKNGLSPLHMAAQGDHVECVKHL
270 280 290 300 310 320
240 250 260 270
pF1KE3 YNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
.. : .. . . : : :.
XP_016 LQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRI
330 340 350 360 370 380
>>XP_016863584 (OMIM: 106410,600919) PREDICTED: ankyrin- (1871 aa)
initn: 522 init1: 177 opt: 362 Z-score: 279.9 bits: 62.3 E(85289): 7.5e-09
Smith-Waterman score: 369; 31.6% identity (64.5% similar) in 231 aa overlap (27-254:122-343)
10 20 30 40 50
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAA
. .:. .::.: . . .:.: : .
XP_016 VKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQ
100 110 120 130 140 150
60 70 80 90 100 110
pF1KE3 RGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSND
.:... : ..::. . :. . ::: :: . .. : :.:.... .:. .:..
XP_016 QGHNQAVAILLENDTKGKVR-----LPALHIAARKDDTKSAALLLQNDHNADV---QSKS
160 170 180 190 200
120 130 140 150 160 170
pF1KE3 GWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANI
:.::::.::::: . . :::. : :: . .: :::..: : .. ::.:::....:
XP_016 GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQI
210 220 230 240 250 260
180 190 200 210 220 230
pF1KE3 DIQ--NGFLLRYAVIKSNHSYC-RMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARML
: . .:. . . .:.:. ...:.::: :.: ..: .:::..: : : :.. :
XP_016 DAKTRDGLTPLHCAARSGHDQVVELLLERGAPL-LARTKNGLSPLHMAAQGDHVECVKHL
270 280 290 300 310 320
240 250 260 270
pF1KE3 YNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
.. : .. . . : : :.
XP_016 LQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRI
330 340 350 360 370 380
>--
initn: 426 init1: 135 opt: 312 Z-score: 244.2 bits: 55.7 E(85289): 7.3e-07
Smith-Waterman score: 381; 32.7% identity (63.3% similar) in 245 aa overlap (13-254:467-706)
10 20 30 40
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNG
.:. .. : : .. :. .:.. :..
XP_016 TALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDA
440 450 460 470 480 490
50 60 70 80 90 100
pF1KE3 RDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLE
.::.: ::.:: .:. . :.:: :: .. ::: :: :: .: .:.:.:.
XP_016 ATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATK-KGFTPLHVAAKYGSLDVAKLLLQ
500 510 520 530 540 550
110 120 130 140 150 160
pF1KE3 SEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRER
: .. ...: ::::::::: .. . :::: : . .: :::..: ...
XP_016 ---RRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQ
560 570 580 590 600 610
170 180 190 200 210
pF1KE3 SSCVKILLDHNA--NIDIQNGFL-LRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLH
. .. ::...: :: ..: :. : ... .. ..:..::. ... ..: : ::
XP_016 MQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST-KSGLTSLH
620 630 640 650 660 670
220 230 240 250 260 270
pF1KE3 LSALRDDVLCARMLYNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
:.: .: : : .: ..::: .... : ::: :.
XP_016 LAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKN
680 690 700 710 720 730
XP_016 GYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEV
740 750 760 770 780 790
>>XP_016863569 (OMIM: 106410,600919) PREDICTED: ankyrin- (1970 aa)
initn: 522 init1: 177 opt: 362 Z-score: 279.7 bits: 62.4 E(85289): 7.7e-09
Smith-Waterman score: 369; 31.6% identity (64.5% similar) in 231 aa overlap (27-254:122-343)
10 20 30 40 50
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAA
. .:. .::.: . . .:.: : .
XP_016 VKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQ
100 110 120 130 140 150
60 70 80 90 100 110
pF1KE3 RGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSND
.:... : ..::. . :. . ::: :: . .. : :.:.... .:. .:..
XP_016 QGHNQAVAILLENDTKGKVR-----LPALHIAARKDDTKSAALLLQNDHNADV---QSKS
160 170 180 190 200
120 130 140 150 160 170
pF1KE3 GWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANI
:.::::.::::: . . :::. : :: . .: :::..: : .. ::.:::....:
XP_016 GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQI
210 220 230 240 250 260
180 190 200 210 220 230
pF1KE3 DIQ--NGFLLRYAVIKSNHSYC-RMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARML
: . .:. . . .:.:. ...:.::: :.: ..: .:::..: : : :.. :
XP_016 DAKTRDGLTPLHCAARSGHDQVVELLLERGAPL-LARTKNGLSPLHMAAQGDHVECVKHL
270 280 290 300 310 320
240 250 260 270
pF1KE3 YNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
.. : .. . . : : :.
XP_016 LQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRI
330 340 350 360 370 380
>--
initn: 426 init1: 135 opt: 312 Z-score: 244.0 bits: 55.8 E(85289): 7.5e-07
Smith-Waterman score: 381; 32.7% identity (63.3% similar) in 245 aa overlap (13-254:467-706)
10 20 30 40
pF1KE3 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNG
.:. .. : : .. :. .:.. :..
XP_016 TALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDA
440 450 460 470 480 490
50 60 70 80 90 100
pF1KE3 RDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLE
.::.: ::.:: .:. . :.:: :: .. ::: :: :: .: .:.:.:.
XP_016 ATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATK-KGFTPLHVAAKYGSLDVAKLLLQ
500 510 520 530 540 550
110 120 130 140 150 160
pF1KE3 SEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRER
: .. ...: ::::::::: .. . :::: : . .: :::..: ...
XP_016 ---RRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQ
560 570 580 590 600 610
170 180 190 200 210
pF1KE3 SSCVKILLDHNA--NIDIQNGFL-LRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLH
. .. ::...: :: ..: :. : ... .. ..:..::. ... ..: : ::
XP_016 MQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST-KSGLTSLH
620 630 640 650 660 670
220 230 240 250 260 270
pF1KE3 LSALRDDVLCARMLYNYGADTNTRNYEGQTPLAVSISISGSSRPCLDFLQEVTSM
:.: .: : : .: ..::: .... : ::: :.
XP_016 LAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKN
680 690 700 710 720 730
XP_016 GYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEV
740 750 760 770 780 790
274 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:10:48 2016 done: Sun Nov 6 08:10:49 2016
Total Scan time: 6.200 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]