Result of FASTA (omim) for
pFN21AE3992
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3992, 385 aa
1>>>pF1KE3992 385 - 385 aa - 385 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3565+/-0.000356; mu= 17.1981+/- 0.022
mean_var=79.2040+/-16.091, 0's: 0 Z-trim(115.5): 29 B-trim: 663 in 1/50
Lambda= 0.144112
statistics sampled from 25943 (25960) to 25943 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.684), E-opt: 0.2 (0.304), width: 16
Scan time: 8.180
The best scores are: opt bits E(85289)
NP_001229306 (OMIM: 609844) m7GpppN-mRNA hydrolase ( 385) 2690 568.8 7.5e-162
NP_689837 (OMIM: 609844) m7GpppN-mRNA hydrolase is ( 420) 2204 467.8 2.1e-131
XP_016864652 (OMIM: 609844) PREDICTED: m7GpppN-mRN ( 405) 2090 444.1 2.8e-124
NP_950241 (OMIM: 609229) diphosphoinositol polypho ( 181) 144 39.2 0.0093
>>NP_001229306 (OMIM: 609844) m7GpppN-mRNA hydrolase iso (385 aa)
initn: 2690 init1: 2690 opt: 2690 Z-score: 3026.7 bits: 568.8 E(85289): 7.5e-162
Smith-Waterman score: 2690; 100.0% identity (100.0% similar) in 385 aa overlap (1-385:1-385)
10 20 30 40 50 60
pF1KE3 METKRVEIPGSVLDDLCSRFILHIPSEERDNAIRVCFQIELAHWFYLDFYMQNTPGLPQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 METKRVEIPGSVLDDLCSRFILHIPSEERDNAIRVCFQIELAHWFYLDFYMQNTPGLPQC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GIRDFAKAVFSHCPFLLPQGEDVEKVLDEWKEYKMGVPTYGAIILDETLENVLLVQGYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIRDFAKAVFSHCPFLLPQGEDVEKVLDEWKEYKMGVPTYGAIILDETLENVLLVQGYLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 KSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 PKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 RRFGDSSDSDNGFSSTGSTPAKPTVEKLSRTKFRHSQQLFPDGSPGDQWVKHRQPLQQKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRFGDSSDSDNGFSSTGSTPAKPTVEKLSRTKFRHSQQLFPDGSPGDQWVKHRQPLQQKP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 YNNHSEMSDLLKGKKCEKKLHPRKLQDNFETDAVYDLPSSSEDQLLEHAEGQPVACNGHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNNHSEMSDLLKGKKCEKKLHPRKLQDNFETDAVYDLPSSSEDQLLEHAEGQPVACNGHC
310 320 330 340 350 360
370 380
pF1KE3 KFPFSSRAFLSFKFDHNAIMKILDL
:::::::::::::::::::::::::
NP_001 KFPFSSRAFLSFKFDHNAIMKILDL
370 380
>>NP_689837 (OMIM: 609844) m7GpppN-mRNA hydrolase isofor (420 aa)
initn: 2201 init1: 2201 opt: 2204 Z-score: 2480.1 bits: 467.8 E(85289): 2.1e-131
Smith-Waterman score: 2592; 91.6% identity (91.6% similar) in 417 aa overlap (1-382:1-417)
10 20 30 40 50 60
pF1KE3 METKRVEIPGSVLDDLCSRFILHIPSEERDNAIRVCFQIELAHWFYLDFYMQNTPGLPQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 METKRVEIPGSVLDDLCSRFILHIPSEERDNAIRVCFQIELAHWFYLDFYMQNTPGLPQC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GIRDFAKAVFSHCPFLLPQGEDVEKVLDEWKEYKMGVPTYGAIILDETLENVLLVQGYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 GIRDFAKAVFSHCPFLLPQGEDVEKVLDEWKEYKMGVPTYGAIILDETLENVLLVQGYLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 KSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 KSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 PKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 PKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 RRFGDSSDSDNGFSSTGSTPAKPTVEKLSRTKFRHSQQLFPDGSPGDQWVKHRQPLQQKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 RRFGDSSDSDNGFSSTGSTPAKPTVEKLSRTKFRHSQQLFPDGSPGDQWVKHRQPLQQKP
250 260 270 280 290 300
310 320
pF1KE3 YNNHSEMSDLLKGK-----------------------------------KCEKKLHPRKL
:::::::::::::: :::::::::::
NP_689 YNNHSEMSDLLKGKNQSMRGNGRKQYQDSPNQKKRTNGLQPAKQQNSLMKCEKKLHPRKL
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE3 QDNFETDAVYDLPSSSEDQLLEHAEGQPVACNGHCKFPFSSRAFLSFKFDHNAIMKILDL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 QDNFETDAVYDLPSSSEDQLLEHAEGQPVACNGHCKFPFSSRAFLSFKFDHNAIMKILDL
370 380 390 400 410 420
>>XP_016864652 (OMIM: 609844) PREDICTED: m7GpppN-mRNA hy (405 aa)
initn: 2087 init1: 2087 opt: 2090 Z-score: 2352.2 bits: 444.1 E(85289): 2.8e-124
Smith-Waterman score: 2478; 91.2% identity (91.2% similar) in 400 aa overlap (18-382:3-402)
10 20 30 40 50 60
pF1KE3 METKRVEIPGSVLDDLCSRFILHIPSEERDNAIRVCFQIELAHWFYLDFYMQNTPGLPQC
:::::::::::::::::::::::::::::::::::::::::::
XP_016 MPSRFILHIPSEERDNAIRVCFQIELAHWFYLDFYMQNTPGLPQC
10 20 30 40
70 80 90 100 110 120
pF1KE3 GIRDFAKAVFSHCPFLLPQGEDVEKVLDEWKEYKMGVPTYGAIILDETLENVLLVQGYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIRDFAKAVFSHCPFLLPQGEDVEKVLDEWKEYKMGVPTYGAIILDETLENVLLVQGYLA
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 KSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSGWGFPKGKVNKEEAPHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGI
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE3 PKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKDTKFNPKTRREIRNIEWFSIEKLPCHRNDMTPKSKLGLAPNKFFMAIPFIRPLRDWLS
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 RRFGDSSDSDNGFSSTGSTPAKPTVEKLSRTKFRHSQQLFPDGSPGDQWVKHRQPLQQKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRFGDSSDSDNGFSSTGSTPAKPTVEKLSRTKFRHSQQLFPDGSPGDQWVKHRQPLQQKP
230 240 250 260 270 280
310 320
pF1KE3 YNNHSEMSDLLKGK-----------------------------------KCEKKLHPRKL
:::::::::::::: :::::::::::
XP_016 YNNHSEMSDLLKGKNQSMRGNGRKQYQDSPNQKKRTNGLQPAKQQNSLMKCEKKLHPRKL
290 300 310 320 330 340
330 340 350 360 370 380
pF1KE3 QDNFETDAVYDLPSSSEDQLLEHAEGQPVACNGHCKFPFSSRAFLSFKFDHNAIMKILDL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDNFETDAVYDLPSSSEDQLLEHAEGQPVACNGHCKFPFSSRAFLSFKFDHNAIMKILDL
350 360 370 380 390 400
>>NP_950241 (OMIM: 609229) diphosphoinositol polyphospha (181 aa)
initn: 123 init1: 98 opt: 144 Z-score: 170.5 bits: 39.2 E(85289): 0.0093
Smith-Waterman score: 144; 28.8% identity (52.3% similar) in 132 aa overlap (107-230:29-158)
80 90 100 110 120 130
pF1KE3 LPQGEDVEKVLDEWKEYKMGVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGKVNKEEA
: ..::::.. . : : : .. ::
NP_950 MMKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEE
10 20 30 40 50
140 150 160 170 180 190
pF1KE3 PHDCAAREVFEETGFDIKDYICKDDYIELRINDQLARLYIIPGIPKDTKFNPKTRREI-R
: :.:::.::.: .: . . : . .:. : :. . . . .: :
NP_950 PGGAAVREVYEEAG--VKGKLGRLLGIFEQNQDRKHRTYVYVLTVTEILEDWEDSVNIGR
60 70 80 90 100 110
200 210 220 230 240
pF1KE3 NIEWFSIEK----LPCHR---NDMTPKSKLGLAPNKFFMAIPFIRPLRDWLSRRFGDSSD
. :::..: : ::. .. : ::: .: . ..:
NP_950 KREWFKVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGL
120 130 140 150 160 170
250 260 270 280 290 300
pF1KE3 SDNGFSSTGSTPAKPTVEKLSRTKFRHSQQLFPDGSPGDQWVKHRQPLQQKPYNNHSEMS
NP_950 PSSVR
180
385 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 22:42:47 2016 done: Sat Nov 5 22:42:49 2016
Total Scan time: 8.180 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]